| | | |
| April 29, 2021 | Bridgeport Islanders 2 at Providence Bruins 1 | Final (SO) |
| April 29, 2021 | Stockton Heat 1 at Manitoba Moose 2 | Final (OT) |
| April 29, 2021 | Chicago Wolves 4 at Grand Rapids Griffins 2 | Final |
| April 29, 2021 | Cleveland Monsters 1 at Texas Stars 2 | Final (SO) |
| April 30, 2021 | Wilkes-Barre/Scranton Penguins 3 at Binghamton Devils 1 | Final |
| April 30, 2021 | Rochester Americans 1 at Utica Comets 7 | Final |
| April 30, 2021 | Iowa Wild 1 at Chicago Wolves 4 | Final |
| April 30, 2021 | Ontario Reign 4 at Colorado Eagles 1 | Final |
| April 30, 2021 | Henderson Silver Knights 5 at San Jose Barracuda 7 | Final |
| April 30, 2021 | Tucson Roadrunners 3 at San Diego Gulls 5 | Final |
| May 1, 2021 | Providence Bruins 2 at Hartford Wolf Pack 3 | Final (OT) |
| May 1, 2021 | Belleville Senators 5 at Toronto Marlies 3 | Final |
| May 1, 2021 | Hershey Bears 4 at Wilkes-Barre/Scranton Penguins 3 | Final (OT) |
| May 1, 2021 | Grand Rapids Griffins 2 at Rockford IceHogs 3 | Final |
| May 1, 2021 | Rochester Americans 3 at Syracuse Crunch 1 | Final |
| May 1, 2021 | Binghamton Devils 4 at Lehigh Valley Phantoms 2 | Final |
| May 1, 2021 | Iowa Wild 5 at Chicago Wolves 2 | Final |
| May 1, 2021 | Cleveland Monsters 2 at Texas Stars 5 | Final |
| May 1, 2021 | Henderson Silver Knights 4 at San Jose Barracuda 0 | Final |
| May 1, 2021 | Ontario Reign 5 at Colorado Eagles 4 | Final |
| May 1, 2021 | Tucson Roadrunners 9 at San Diego Gulls 2 | Final |
| May 2, 2021 | Lehigh Valley Phantoms 0 at Hershey Bears 2 | Final |
| May 2, 2021 | Utica Comets 2 at Syracuse Crunch 5 | Final |
| May 2, 2021 | Belleville Senators 4 at Toronto Marlies 1 | Final |
| May 2, 2021 | Cleveland Monsters 3 at Texas Stars 2 | Final (OT) |
| May 3, 2021 | Bakersfield Condors 5 at San Jose Barracuda 3 | Final |
| May 3, 2021 | Providence Bruins 3 at Bridgeport Islanders 4 | Final (SO) |
| May 3, 2021 | Rockford IceHogs 3 at Grand Rapids Griffins 2 | Final (SO) |
| May 3, 2021 | Utica Comets at Rochester Americans | Ppd. |
| May 4, 2021 | Bridgeport Islanders 3 at Hartford Wolf Pack 4 | Final |
| May 4, 2021 | Toronto Marlies 4 at Laval Rocket 3 | Final (OT) |
| May 5, 2021 | Binghamton Devils 3 at Wilkes-Barre/Scranton Penguins 6 | Final |
| May 5, 2021 | Cleveland Monsters 3 at Grand Rapids Griffins 2 | Final |
| May 5, 2021 | Syracuse Crunch 5 at Utica Comets 3 | Final |
| May 5, 2021 | Hershey Bears 3 at Lehigh Valley Phantoms 5 | Final |
| May 5, 2021 | Colorado Eagles 1 at Bakersfield Condors 2 | Final |
| May 5, 2021 | San Diego Gulls 4 at Ontario Reign 6 | Final |
| May 6, 2021 | Hartford Wolf Pack 3 at Providence Bruins 6 | Final |
| May 6, 2021 | Manitoba Moose 5 at Toronto Marlies 3 | Final |
| May 6, 2021 | Tucson Roadrunners 2 at Texas Stars 7 | Final |
| May 7, 2021 | Hershey Bears 2 at Binghamton Devils 1 | Final |
| May 7, 2021 | Chicago Wolves 4 at Grand Rapids Griffins 5 | Final |
| May 7, 2021 | Belleville Senators 4 at Laval Rocket 3 | Final |
| May 7, 2021 | Syracuse Crunch 4 at Utica Comets 5 | Final (OT) |
| May 7, 2021 | Rockford IceHogs 1 at Iowa Wild 6 | Final |
| May 7, 2021 | Colorado Eagles at Bakersfield Condors | Ppd. |
| May 7, 2021 | Ontario Reign 7 at San Diego Gulls 4 | Final |
| May 8, 2021 | Lehigh Valley Phantoms 0 at Hershey Bears 3 | Final |
| May 8, 2021 | Manitoba Moose 5 at Toronto Marlies 4 | Final (SO) |
| May 8, 2021 | San Jose Barracuda 3 at Henderson Silver Knights 5 | Final |
| May 8, 2021 | Binghamton Devils 1 at Wilkes-Barre/Scranton Penguins 4 | Final |
| May 8, 2021 | Rochester Americans 4 at Cleveland Monsters 3 | Final (SO) |
| May 8, 2021 | Utica Comets 2 at Syracuse Crunch 4 | Final |
| May 8, 2021 | Grand Rapids Griffins 3 at Chicago Wolves 1 | Final |
| May 8, 2021 | Tucson Roadrunners 5 at Texas Stars 2 | Final |
| May 8, 2021 | San Diego Gulls 4 at Bakersfield Condors 1 | Final |
| May 9, 2021 | Manitoba Moose 4 at Toronto Marlies 3 | Final |
| May 9, 2021 | Wilkes-Barre/Scranton Penguins 2 at Lehigh Valley Phantoms 6 | Final |
| May 9, 2021 | Colorado Eagles 7 at Ontario Reign 5 | Final |
| May 9, 2021 | Iowa Wild 2 at Rockford IceHogs 0 | Final |
| May 9, 2021 | Tucson Roadrunners 1 at Texas Stars 3 | Final |
| May 10, 2021 | Syracuse Crunch 0 at Utica Comets 3 | Final |
| May 10, 2021 | Rockford IceHogs 5 at Chicago Wolves 6 | Final |
| May 11, 2021 | Manitoba Moose 3 at Belleville Senators 4 | Final (SO) |
| May 11, 2021 | Grand Rapids Griffins 2 at Cleveland Monsters 0 | Final |
| May 11, 2021 | Laval Rocket 4 at Toronto Marlies 2 | Final |
| May 11, 2021 | San Jose Barracuda 1 at Henderson Silver Knights 3 | Final |
| May 12, 2021 | Laval Rocket 2 at Toronto Marlies 3 | Final |
| May 12, 2021 | Syracuse Crunch at Wilkes-Barre/Scranton Penguins | Cancelled |
| May 12, 2021 | Lehigh Valley Phantoms 2 at Binghamton Devils 1 | Final |
| May 12, 2021 | Chicago Wolves 7 at Grand Rapids Griffins 0 | Final |
| May 12, 2021 | Rochester Americans 1 at Utica Comets 3 | Final |
| May 12, 2021 | Texas Stars 1 at Iowa Wild 3 | Final |
| May 12, 2021 | San Diego Gulls 1 at Colorado Eagles 2 | Final |
| May 13, 2021 | Bakersfield Condors 0 at Henderson Silver Knights 5 | Final |
| May 14, 2021 | Manitoba Moose 2 at Belleville Senators 3 | Final (OT) |
| May 14, 2021 | Grand Rapids Griffins 4 at Cleveland Monsters 6 | Final |
| May 14, 2021 | Toronto Marlies 3 at Laval Rocket 2 | Final |
| May 14, 2021 | Chicago Wolves 1 at Rockford IceHogs 4 | Final |
| May 14, 2021 | Utica Comets 1 at Rochester Americans 0 | Final |
| May 14, 2021 | Texas Stars 4 at Iowa Wild 5 | Final |
| May 14, 2021 | Ontario Reign 3 at Tucson Roadrunners 2 | Final (OT) |
| May 14, 2021 | San Diego Gulls 4 at Colorado Eagles 1 | Final |
| May 15, 2021 | Binghamton Devils 2 at Hershey Bears 3 | Final |
| May 15, 2021 | Toronto Marlies 3 at Laval Rocket 2 | Final (OT) |
| May 15, 2021 | Bakersfield Condors 3 at Henderson Silver Knights 2 | Final |
| May 15, 2021 | Manitoba Moose 2 at Belleville Senators 3 | Final |
| May 15, 2021 | Cleveland Monsters 1 at Grand Rapids Griffins 4 | Final |
| May 15, 2021 | Texas Stars 3 at Iowa Wild 2 | Final |
| May 15, 2021 | Wilkes-Barre/Scranton Penguins 2 at Lehigh Valley Phantoms 1 | Final (OT) |
| May 15, 2021 | Syracuse Crunch 5 at Rochester Americans 3 | Final |
| May 15, 2021 | Rockford IceHogs 1 at Chicago Wolves 3 | Final |
| May 15, 2021 | San Diego Gulls 3 at Colorado Eagles 2 | Final (OT) |
| May 16, 2021 | Wilkes-Barre/Scranton Penguins 2 at Hershey Bears 5 | Final |
| May 16, 2021 | Binghamton Devils 4 at Lehigh Valley Phantoms 3 | Final (SO) |
| May 16, 2021 | Manitoba Moose 1 at Belleville Senators 6 | Final |
| May 16, 2021 | Bakersfield Condors 4 at Henderson Silver Knights 3 | Final (SO) |
| May 16, 2021 | Ontario Reign 9 at Tucson Roadrunners 4 | Final |
| May 16, 2021 | Utica Comets 1 at Rochester Americans 2 | Final |
| May 17, 2021 | Toronto Marlies 2 at Laval Rocket 0 | Final |
| May 18, 2021 | Tucson Roadrunners 1 at San Jose Barracuda 2 (Playoff) | Final |
| May 18, 2021 | Ontario Reign 4 at Colorado Eagles 5 (Playoff) | Final (OT) |
| May 19, 2021 | Toronto Marlies 4 at Belleville Senators 6 | Final |
| May 19, 2021 | Colorado Eagles 1 at San Jose Barracuda 5 (Playoff) | Final |
| May 20, 2021 | Toronto Marlies 6 at Belleville Senators 3 | Final |
| May 21, 2021 | San Jose Barracuda 1 at Henderson Silver Knights 4 (Playoff Gm. 1) | Final |
| May 21, 2021 | San Diego Gulls 5 at Bakersfield Condors 3 (Playoff Gm. 1) | Final |
| May 23, 2021 | Henderson Silver Knights 4 at San Jose Barracuda 2 (Playoff Gm. 2) | Final |
| May 23, 2021 | Bakersfield Condors 3 at San Diego Gulls 2 (Playoff Gm. 2) | Final (OT) |
| May 24, 2021 | San Diego Gulls 1 at Bakersfield Condors 2 (Playoff Gm. 3) | Final (OT) |
| May 26, 2021 | Bakersfield Condors 3 at Henderson Silver Knights 2 (Division Final Gm. 1) | Final (OT) |
| May 27, 2021 | Henderson Silver Knights 6 at Bakersfield Condors 3 (Division Final Gm. 2; Henderson) | Final |
| May 29, 2021 | Bakersfield Condors 3 at Henderson Silver Knights 2 (Division Final Gm. 3) | Final |
| October 15, 2021 | Syracuse Crunch 6 at Cleveland Monsters 4 | Final |
| October 15, 2021 | Rockford IceHogs 1 at Grand Rapids Griffins 6 | Final |
| October 15, 2021 | Bridgeport Islanders 1 at Hartford Wolf Pack 2 | Final |
| October 15, 2021 | Belleville Senators 2 at Laval Rocket 6 | Final |
| October 15, 2021 | Colorado Eagles 4 at Henderson Silver Knights 5 | Final (SO) |
| October 15, 2021 | Tucson Roadrunners 1 at Stockton Heat 0 | Final (OT) |
| October 16, 2021 | Manitoba Moose 1 at Toronto Marlies 5 | Final |
| October 16, 2021 | Lehigh Valley Phantoms 1 at Wilkes-Barre/Scranton Penguins 2 | Final |
| October 16, 2021 | Laval Rocket 2 at Belleville Senators 5 | Final |
| October 16, 2021 | Syracuse Crunch 4 at Cleveland Monsters 5 | Final (OT) |
| October 16, 2021 | Charlotte Checkers 2 at Hershey Bears 5 | Final |
| October 16, 2021 | Grand Rapids Griffins 3 at Milwaukee Admirals 7 | Final |
| October 16, 2021 | Bridgeport Islanders 1 at Providence Bruins 2 | Final (SO) |
| October 16, 2021 | Hartford Wolf Pack 1 at Springfield Thunderbirds 2 | Final |
| October 16, 2021 | Rockford IceHogs 5 at Chicago Wolves 3 | Final |
| October 16, 2021 | Iowa Wild 2 at Texas Stars 0 | Final |
| October 16, 2021 | San Diego Gulls 2 at Ontario Reign 5 | Final |
| October 16, 2021 | Tucson Roadrunners 2 at Stockton Heat 3 | Final |
| October 16, 2021 | Abbotsford Canucks 3 at Bakersfield Condors 5 | Final |
| October 17, 2021 | Providence Bruins 3 at Hartford Wolf Pack 4 | Final (SO) |
| October 17, 2021 | Lehigh Valley Phantoms 1 at Hershey Bears 2 | Final |
| October 17, 2021 | Rochester Americans 2 at Utica Comets 6 | Final |
| October 17, 2021 | Bridgeport Islanders 3 at Springfield Thunderbirds 4 | Final (SO) |
| October 17, 2021 | Charlotte Checkers 4 at Wilkes-Barre/Scranton Penguins 1 | Final |
| October 17, 2021 | Manitoba Moose 5 at Toronto Marlies 0 | Final |
| October 17, 2021 | Iowa Wild 1 at Texas Stars 3 | Final |
| October 17, 2021 | Colorado Eagles 3 at Henderson Silver Knights 6 | Final |
| October 17, 2021 | San Jose Barracuda 0 at Bakersfield Condors 1 | Final |
| October 17, 2021 | Abbotsford Canucks 3 at Ontario Reign 2 | Final (SO) |
| October 19, 2021 | Abbotsford Canucks 3 at Ontario Reign 4 | Final (OT) |
| October 20, 2021 | Manitoba Moose 4 at Laval Rocket 5 | Final |
| October 22, 2021 | Cleveland Monsters 4 at Belleville Senators 0 | Final |
| October 22, 2021 | Hershey Bears 3 at Charlotte Checkers 5 | Final |
| October 22, 2021 | Providence Bruins 1 at Utica Comets 2 | Final (OT) |
| October 22, 2021 | Syracuse Crunch 3 at Rochester Americans 5 | Final |
| October 22, 2021 | Bridgeport Islanders 1 at Springfield Thunderbirds 3 | Final |
| October 22, 2021 | Hartford Wolf Pack 1 at Wilkes-Barre/Scranton Penguins 2 | Final (OT) |
| October 22, 2021 | Rockford IceHogs 3 at Iowa Wild 6 | Final |
| October 22, 2021 | Grand Rapids Griffins 0 at Manitoba Moose 1 | Final |
| October 22, 2021 | Chicago Wolves 3 at Milwaukee Admirals 2 | Final |
| October 22, 2021 | San Jose Barracuda 5 at Colorado Eagles 4 | Final |
| October 22, 2021 | Henderson Silver Knights 2 at Abbotsford Canucks 3 | Final (OT) |
| October 22, 2021 | Bakersfield Condors 2 at Ontario Reign 3 | Final |
| October 22, 2021 | Stockton Heat 6 at San Diego Gulls 2 | Final |
| October 23, 2021 | Rochester Americans 7 at Toronto Marlies 3 | Final |
| October 23, 2021 | Hershey Bears 2 at Charlotte Checkers 1 | Final (OT) |
| October 23, 2021 | Cleveland Monsters 2 at Belleville Senators 1 | Final |
| October 23, 2021 | Springfield Thunderbirds 3 at Bridgeport Islanders 4 | Final (OT) |
| October 23, 2021 | Rockford IceHogs 2 at Iowa Wild 5 | Final |
| October 23, 2021 | Utica Comets 2 at Syracuse Crunch 1 | Final |
| October 23, 2021 | Hartford Wolf Pack 3 at Lehigh Valley Phantoms 1 | Final |
| October 23, 2021 | Laval Rocket 4 at Providence Bruins 0 | Final |
| October 23, 2021 | Milwaukee Admirals 1 at Chicago Wolves 6 | Final |
| October 23, 2021 | San Diego Gulls 1 at Ontario Reign 5 | Final |
| October 23, 2021 | Texas Stars 0 at Tucson Roadrunners 4 | Final |
| October 23, 2021 | San Jose Barracuda 3 at Colorado Eagles 2 | Final |
| October 23, 2021 | Stockton Heat 4 at Bakersfield Condors 2 | Final |
| October 24, 2021 | Laval Rocket 0 at Bridgeport Islanders 3 | Final |
| October 24, 2021 | Grand Rapids Griffins 2 at Manitoba Moose 3 | Final (SO) |
| October 24, 2021 | Wilkes-Barre/Scranton Penguins 2 at Lehigh Valley Phantoms 1 | Final (OT) |
| October 24, 2021 | Springfield Thunderbirds 4 at Providence Bruins 1 | Final |
| October 24, 2021 | Cleveland Monsters 2 at Toronto Marlies 3 | Final (SO) |
| October 24, 2021 | Texas Stars 6 at Tucson Roadrunners 2 | Final |
| October 24, 2021 | Henderson Silver Knights 0 at Abbotsford Canucks 3 | Final |
| October 27, 2021 | Rochester Americans 3 at Belleville Senators 7 | Final |
| October 27, 2021 | Chicago Wolves 3 at Grand Rapids Griffins 0 | Final |
| October 27, 2021 | Syracuse Crunch 3 at Hershey Bears 2 | Final (OT) |
| October 27, 2021 | Lehigh Valley Phantoms 2 at Wilkes-Barre/Scranton Penguins 4 | Final |
| October 27, 2021 | Toronto Marlies 0 at Laval Rocket 5 | Final |
| October 27, 2021 | Colorado Eagles 4 at Bakersfield Condors 5 | Final |
| October 28, 2021 | Rockford IceHogs 1 at Texas Stars 4 | Final |
| October 29, 2021 | Wilkes-Barre/Scranton Penguins 2 at Hartford Wolf Pack 3 | Final (SO) |
| October 29, 2021 | Bakersfield Condors 3 at Henderson Silver Knights 2 | Final |
| October 29, 2021 | Toronto Marlies 5 at Belleville Senators 2 | Final |
| October 29, 2021 | Rochester Americans 4 at Laval Rocket 3 | Final |
| October 29, 2021 | Cleveland Monsters 2 at Syracuse Crunch 3 | Final (SO) |
| October 29, 2021 | Lehigh Valley Phantoms 2 at Utica Comets 5 | Final |
| October 29, 2021 | Charlotte Checkers 3 at Providence Bruins 4 | Final |
| October 29, 2021 | Chicago Wolves 4 at Milwaukee Admirals 2 | Final |
| October 29, 2021 | San Diego Gulls 5 at Tucson Roadrunners 1 | Final |
| October 29, 2021 | Ontario Reign 5 at Abbotsford Canucks 2 | Final |
| October 29, 2021 | Colorado Eagles 5 at San Jose Barracuda 4 | Final (OT) |
| October 30, 2021 | Rochester Americans 6 at Laval Rocket 5 | Final (OT) |
| October 30, 2021 | Iowa Wild 3 at Manitoba Moose 5 | Final |
| October 30, 2021 | Belleville Senators 2 at Toronto Marlies 5 | Final |
| October 30, 2021 | Providence Bruins 4 at Bridgeport Islanders 6 | Final |
| October 30, 2021 | Milwaukee Admirals 1 at Grand Rapids Griffins 4 | Final |
| October 30, 2021 | Charlotte Checkers 3 at Hartford Wolf Pack 2 | Final |
| October 30, 2021 | Bakersfield Condors 2 at Henderson Silver Knights 4 | Final |
| October 30, 2021 | Cleveland Monsters 2 at Hershey Bears 1 | Final (SO) |
| October 30, 2021 | Syracuse Crunch 3 at Lehigh Valley Phantoms 2 | Final (OT) |
| October 30, 2021 | Wilkes-Barre/Scranton Penguins 4 at Springfield Thunderbirds 3 | Final (OT) |
| October 30, 2021 | Rockford IceHogs 4 at Texas Stars 3 | Final |
| October 30, 2021 | Colorado Eagles 3 at Stockton Heat 6 | Final |
| October 30, 2021 | San Diego Gulls 4 at Tucson Roadrunners 6 | Final |
| October 30, 2021 | Ontario Reign 3 at Abbotsford Canucks 2 | Final (OT) |
| October 31, 2021 | Charlotte Checkers 3 at Springfield Thunderbirds 5 | Final |
| October 31, 2021 | Hartford Wolf Pack 5 at Bridgeport Islanders 1 | Final |
| October 31, 2021 | Iowa Wild 4 at Manitoba Moose 1 | Final |
| October 31, 2021 | Chicago Wolves 6 at Grand Rapids Griffins 3 | Final |
| October 31, 2021 | Cleveland Monsters 3 at Hershey Bears 4 | Final (OT) |
| October 31, 2021 | San Jose Barracuda at Stockton Heat | Ppd. |
| November 2, 2021 | Texas Stars 1 at Colorado Eagles 2 | Final |
| November 3, 2021 | Wilkes-Barre/Scranton Penguins 0 at Lehigh Valley Phantoms 4 | Final |
| November 3, 2021 | Belleville Senators 3 at Rochester Americans 4 | Final |
| November 3, 2021 | Texas Stars 1 at Colorado Eagles 4 | Final |
| November 3, 2021 | Ontario Reign 5 at Henderson Silver Knights 2 | Final |
| November 3, 2021 | Stockton Heat 4 at San Jose Barracuda 1 | Final |
| November 5, 2021 | Belleville Senators 6 at Cleveland Monsters 2 | Final |
| November 5, 2021 | Bridgeport Islanders 4 at Hartford Wolf Pack 7 | Final |
| November 5, 2021 | Grand Rapids Griffins 6 at Iowa Wild 5 | Final (OT) |
| November 5, 2021 | Utica Comets 6 at Syracuse Crunch 3 | Final |
| November 5, 2021 | Toronto Marlies 4 at Rochester Americans 1 | Final |
| November 5, 2021 | Hershey Bears 2 at Springfield Thunderbirds 3 | Final (OT) |
| November 5, 2021 | Providence Bruins 6 at Wilkes-Barre/Scranton Penguins 2 | Final |
| November 5, 2021 | Manitoba Moose 1 at Milwaukee Admirals 2 | Final (OT) |
| November 5, 2021 | Tucson Roadrunners 0 at Henderson Silver Knights 3 | Final |
| November 5, 2021 | Bakersfield Condors 2 at San Diego Gulls 3 | Final (SO) |
| November 5, 2021 | Abbotsford Canucks 2 at Stockton Heat 3 | Final |
| November 6, 2021 | Providence Bruins 3 at Hershey Bears 0 | Final |
| November 6, 2021 | Toronto Marlies 2 at Utica Comets 5 | Final |
| November 6, 2021 | Texas Stars 7 at San Jose Barracuda 3 | Final |
| November 6, 2021 | Lehigh Valley Phantoms 3 at Charlotte Checkers 7 | Final |
| November 6, 2021 | Springfield Thunderbirds 4 at Bridgeport Islanders 1 | Final |
| November 6, 2021 | Belleville Senators 3 at Cleveland Monsters 2 | Final (SO) |
| November 6, 2021 | Wilkes-Barre/Scranton Penguins 3 at Hartford Wolf Pack 4 | Final |
| November 6, 2021 | Iowa Wild 2 at Milwaukee Admirals 5 | Final |
| November 6, 2021 | Grand Rapids Griffins 2 at Rockford IceHogs 1 | Final |
| November 6, 2021 | Laval Rocket 0 at Syracuse Crunch 4 | Final |
| November 6, 2021 | Manitoba Moose 5 at Chicago Wolves 1 | Final |
| November 6, 2021 | Abbotsford Canucks 1 at Stockton Heat 2 | Final |
| November 6, 2021 | Ontario Reign 6 at Bakersfield Condors 3 | Final |
| November 6, 2021 | Tucson Roadrunners 2 at Henderson Silver Knights 3 | Final (OT) |
| November 6, 2021 | Colorado Eagles 3 at San Diego Gulls 2 | Final |
| November 7, 2021 | Lehigh Valley Phantoms 5 at Charlotte Checkers 3 | Final |
| November 7, 2021 | Hartford Wolf Pack 2 at Bridgeport Islanders 3 | Final |
| November 7, 2021 | Springfield Thunderbirds 3 at Hershey Bears 5 | Final |
| November 7, 2021 | Milwaukee Admirals 2 at Chicago Wolves 4 | Final |
| November 7, 2021 | Manitoba Moose 3 at Rockford IceHogs 4 | Final |
| November 7, 2021 | Laval Rocket 2 at Utica Comets 4 | Final |
| November 7, 2021 | Colorado Eagles 3 at Ontario Reign 4 | Final |
| November 7, 2021 | Texas Stars 5 at San Jose Barracuda 7 | Final |
| November 10, 2021 | Lehigh Valley Phantoms 4 at Hershey Bears 1 | Final |
| November 10, 2021 | Bridgeport Islanders 3 at Syracuse Crunch 1 | Final |
| November 10, 2021 | Springfield Thunderbirds 4 at Providence Bruins 1 | Final |
| November 10, 2021 | Rochester Americans 5 at Wilkes-Barre/Scranton Penguins 1 | Final |
| November 10, 2021 | Belleville Senators 0 at Laval Rocket 3 | Final |
| November 10, 2021 | Manitoba Moose 4 at Milwaukee Admirals 3 | Final (OT) |
| November 10, 2021 | Iowa Wild 4 at Rockford IceHogs 3 | Final (OT) |
| November 10, 2021 | Stockton Heat 5 at Bakersfield Condors 4 | Final (OT) |
| November 10, 2021 | Henderson Silver Knights 3 at San Diego Gulls 6 | Final |
| November 11, 2021 | Syracuse Crunch 1 at Utica Comets 3 | Final |
| November 12, 2021 | Henderson Silver Knights 2 at Stockton Heat 3 | Final (SO) |
| November 12, 2021 | Manitoba Moose 0 at Grand Rapids Griffins 2 | Final |
| November 12, 2021 | Bridgeport Islanders 4 at Laval Rocket 5 | Final (OT) |
| November 12, 2021 | Lehigh Valley Phantoms 3 at Providence Bruins 6 | Final |
| November 12, 2021 | Cleveland Monsters 4 at Rochester Americans 3 | Final |
| November 12, 2021 | Hartford Wolf Pack 6 at Springfield Thunderbirds 4 | Final |
| November 12, 2021 | Charlotte Checkers 1 at Wilkes-Barre/Scranton Penguins 2 | Final |
| November 12, 2021 | Chicago Wolves 4 at Rockford IceHogs 1 | Final |
| November 12, 2021 | Colorado Eagles 2 at Texas Stars 1 | Final (SO) |
| November 12, 2021 | Ontario Reign 4 at Tucson Roadrunners 8 | Final |
| November 12, 2021 | San Jose Barracuda 1 at Abbotsford Canucks 7 | Final |
| November 12, 2021 | Bakersfield Condors 2 at San Diego Gulls 1 | Final (OT) |
| November 13, 2021 | Hartford Wolf Pack 2 at Providence Bruins 1 | Final (OT) |
| November 13, 2021 | Utica Comets 5 at Laval Rocket 3 | Final |
| November 13, 2021 | Cleveland Monsters 0 at Rochester Americans 4 | Final |
| November 13, 2021 | Charlotte Checkers 4 at Wilkes-Barre/Scranton Penguins 0 | Final |
| November 13, 2021 | Bridgeport Islanders 2 at Belleville Senators 3 | Final |
| November 13, 2021 | Manitoba Moose 6 at Grand Rapids Griffins 2 | Final |
| November 13, 2021 | Milwaukee Admirals 0 at Iowa Wild 5 | Final |
| November 13, 2021 | Hershey Bears 5 at Syracuse Crunch 4 | Final (SO) |
| November 13, 2021 | Springfield Thunderbirds 2 at Lehigh Valley Phantoms 1 | Final (OT) |
| November 13, 2021 | Toronto Marlies 5 at Chicago Wolves 1 | Final |
| November 13, 2021 | Colorado Eagles 3 at Texas Stars 4 | Final (SO) |
| November 13, 2021 | Henderson Silver Knights 4 at Stockton Heat 3 | Final (OT) |
| November 13, 2021 | Ontario Reign 6 at Tucson Roadrunners 3 | Final |
| November 13, 2021 | San Diego Gulls 2 at Bakersfield Condors 4 | Final |
| November 14, 2021 | Utica Comets 4 at Belleville Senators 1 | Final |
| November 14, 2021 | Toronto Marlies 2 at Chicago Wolves 1 | Final (OT) |
| November 14, 2021 | Milwaukee Admirals 3 at Iowa Wild 4 | Final |
| November 14, 2021 | Charlotte Checkers 5 at Hershey Bears 2 | Final |
| November 14, 2021 | San Jose Barracuda 3 at Abbotsford Canucks 2 | Final |
| November 17, 2021 | Chicago Wolves 2 at Grand Rapids Griffins 1 | Final (OT) |
| November 17, 2021 | Syracuse Crunch 1 at Cleveland Monsters 2 | Final (OT) |
| November 17, 2021 | Bridgeport Islanders 3 at Hartford Wolf Pack 4 | Final |
| November 17, 2021 | Laval Rocket 6 at Toronto Marlies 5 | Final (SO) |
| November 17, 2021 | Charlotte Checkers 4 at Lehigh Valley Phantoms 3 | Final |
| November 17, 2021 | Utica Comets 3 at Rochester Americans 2 | Final |
| November 17, 2021 | Bakersfield Condors 3 at San Jose Barracuda 4 | Final |
| November 18, 2021 | Milwaukee Admirals 2 at Manitoba Moose 6 | Final |
| November 19, 2021 | Syracuse Crunch 1 at Cleveland Monsters 5 | Final |
| November 19, 2021 | Charlotte Checkers 1 at Utica Comets 4 | Final |
| November 19, 2021 | Hartford Wolf Pack 1 at Providence Bruins 2 | Final (OT) |
| November 19, 2021 | Lehigh Valley Phantoms 4 at Rochester Americans 5 | Final (SO) |
| November 19, 2021 | Wilkes-Barre/Scranton Penguins 4 at Springfield Thunderbirds 5 | Final (SO) |
| November 19, 2021 | Tucson Roadrunners 0 at Iowa Wild 5 | Final |
| November 19, 2021 | Milwaukee Admirals 3 at Manitoba Moose 4 | Final |
| November 19, 2021 | Chicago Wolves 3 at Rockford IceHogs 6 | Final |
| November 19, 2021 | Grand Rapids Griffins 5 at Texas Stars 4 | Final (OT) |
| November 19, 2021 | Henderson Silver Knights 3 at Colorado Eagles 2 | Final |
| November 19, 2021 | San Diego Gulls 4 at San Jose Barracuda 3 | Final |
| November 20, 2021 | Lehigh Valley Phantoms 2 at Toronto Marlies 3 | Final (OT) |
| November 20, 2021 | San Diego Gulls 2 at San Jose Barracuda 1 | Final |
| November 20, 2021 | Laval Rocket 2 at Belleville Senators 5 | Final |
| November 20, 2021 | Rochester Americans 3 at Utica Comets 5 | Final |
| November 20, 2021 | Wilkes-Barre/Scranton Penguins 3 at Providence Bruins 1 | Final |
| November 20, 2021 | Bridgeport Islanders 1 at Springfield Thunderbirds 2 | Final |
| November 20, 2021 | Hershey Bears 3 at Hartford Wolf Pack 7 | Final |
| November 20, 2021 | Rockford IceHogs 3 at Chicago Wolves 2 | Final (SO) |
| November 20, 2021 | Grand Rapids Griffins 3 at Texas Stars 4 | Final (OT) |
| November 20, 2021 | Henderson Silver Knights 1 at Colorado Eagles 2 | Final |
| November 21, 2021 | Tucson Roadrunners 2 at Iowa Wild 1 | Final |
| November 21, 2021 | Springfield Thunderbirds 5 at Bridgeport Islanders 2 | Final |
| November 21, 2021 | Milwaukee Admirals 5 at Manitoba Moose 2 | Final |
| November 21, 2021 | Cleveland Monsters 6 at Toronto Marlies 5 | Final (OT) |
| November 21, 2021 | Charlotte Checkers 2 at Hershey Bears 4 | Final |
| November 21, 2021 | Stockton Heat 4 at Ontario Reign 2 | Final |
| November 22, 2021 | Stockton Heat 3 at Ontario Reign 5 | Final |
| November 23, 2021 | Wilkes-Barre/Scranton Penguins 3 at Charlotte Checkers 2 | Final (OT) |
| November 24, 2021 | Bridgeport Islanders 1 at Springfield Thunderbirds 4 | Final |
| November 24, 2021 | Wilkes-Barre/Scranton Penguins 3 at Charlotte Checkers 4 | Final |
| November 24, 2021 | Providence Bruins 3 at Hershey Bears 4 | Final (OT) |
| November 24, 2021 | Belleville Senators 3 at Syracuse Crunch 2 | Final |
| November 24, 2021 | Rochester Americans 4 at Utica Comets 2 | Final |
| November 24, 2021 | Grand Rapids Griffins 6 at Milwaukee Admirals 3 | Final |
| November 24, 2021 | San Jose Barracuda 1 at San Diego Gulls 5 | Final |
| November 26, 2021 | Providence Bruins 3 at Bridgeport Islanders 2 | Final |
| November 26, 2021 | Toronto Marlies 1 at Cleveland Monsters 5 | Final |
| November 26, 2021 | Chicago Wolves 5 at Grand Rapids Griffins 3 | Final |
| November 26, 2021 | Springfield Thunderbirds 3 at Hartford Wolf Pack 5 | Final |
| November 26, 2021 | Belleville Senators 6 at Laval Rocket 2 | Final |
| November 26, 2021 | Lehigh Valley Phantoms 1 at Syracuse Crunch 4 | Final |
| November 26, 2021 | Hershey Bears 3 at Rochester Americans 7 | Final |
| November 26, 2021 | Milwaukee Admirals 5 at Rockford IceHogs 2 | Final |
| November 26, 2021 | San Jose Barracuda 2 at San Diego Gulls 4 | Final |
| November 26, 2021 | Abbotsford Canucks 1 at Tucson Roadrunners 4 | Final |
| November 26, 2021 | Stockton Heat 3 at Colorado Eagles 2 | Final (OT) |
| November 26, 2021 | Bakersfield Condors at Ontario Reign | Ppd. |
| November 27, 2021 | Hartford Wolf Pack 2 at Springfield Thunderbirds 4 | Final |
| November 27, 2021 | Iowa Wild 2 at Henderson Silver Knights 1 | Final |
| November 27, 2021 | Texas Stars 1 at Manitoba Moose 4 | Final |
| November 27, 2021 | Cleveland Monsters 3 at Toronto Marlies 4 | Final (OT) |
| November 27, 2021 | Stockton Heat 1 at Colorado Eagles 5 | Final |
| November 27, 2021 | Utica Comets 1 at Charlotte Checkers 0 | Final |
| November 27, 2021 | Providence Bruins 5 at Wilkes-Barre/Scranton Penguins 1 | Final |
| November 27, 2021 | Laval Rocket 3 at Belleville Senators 7 | Final |
| November 27, 2021 | Rochester Americans 4 at Syracuse Crunch 2 | Final |
| November 27, 2021 | Bridgeport Islanders 4 at Lehigh Valley Phantoms 1 | Final |
| November 27, 2021 | Rockford IceHogs 2 at Chicago Wolves 3 | Final (SO) |
| November 27, 2021 | Abbotsford Canucks 4 at Tucson Roadrunners 5 | Final |
| November 27, 2021 | San Jose Barracuda at Ontario Reign | Ppd. |
| November 27, 2021 | San Diego Gulls 2 at Bakersfield Condors 1 | Final |
| November 28, 2021 | Utica Comets 5 at Charlotte Checkers 2 | Final |
| November 28, 2021 | Texas Stars 3 at Manitoba Moose 5 | Final |
| November 28, 2021 | Grand Rapids Griffins 0 at Chicago Wolves 3 | End of 2nd |
| November 28, 2021 | Iowa Wild 3 at Henderson Silver Knights 2 | End of 2nd |
| November 28, 2021 | Milwaukee Admirals 1 at Rockford IceHogs 1 | End of 1st |
| November 28, 2021 | Lehigh Valley Phantoms at Hershey Bears | Ppd. |
| November 30, 2021 | Ontario Reign at Abbotsford Canucks | 10:00 p.m. |
| December 1, 2021 | Springfield Thunderbirds at Hartford Wolf Pack | 7:00 p.m. |
| December 1, 2021 | Belleville Senators at Utica Comets | 7:00 p.m. |
| December 1, 2021 | Syracuse Crunch at Rochester Americans | 7:05 p.m. |
| December 1, 2021 | Hershey Bears at Lehigh Valley Phantoms | Ppd. |
| December 1, 2021 | Texas Stars at Laval Rocket | 7:30 p.m. |
| December 1, 2021 | Rockford IceHogs at Milwaukee Admirals | 8:00 p.m. |
| December 1, 2021 | Bakersfield Condors at Stockton Heat | 9:30 p.m. |
| December 1, 2021 | Ontario Reign at Abbotsford Canucks | 10:00 p.m. |
| December 2, 2021 | Iowa Wild at Chicago Wolves | 8:00 p.m. |
| December 3, 2021 | Milwaukee Admirals at Cleveland Monsters | 7:00 p.m. |
| December 3, 2021 | Rockford IceHogs at Grand Rapids Griffins | 7:00 p.m. |
| December 3, 2021 | Texas Stars at Laval Rocket | 7:00 p.m. |
| December 3, 2021 | Wilkes-Barre/Scranton Penguins at Syracuse Crunch | 7:00 p.m. |
| December 3, 2021 | Charlotte Checkers at Lehigh Valley Phantoms | 7:05 p.m. |
| December 3, 2021 | Hartford Wolf Pack at Providence Bruins | 7:05 p.m. |
| December 3, 2021 | Springfield Thunderbirds at Rochester Americans | 7:05 p.m. |
| December 3, 2021 | Tucson Roadrunners at Colorado Eagles | 9:05 p.m. |
| December 3, 2021 | Henderson Silver Knights at Bakersfield Condors | 10:00 p.m. |
| December 3, 2021 | San Diego Gulls at Stockton Heat | 10:00 p.m. |
| December 4, 2021 | Springfield Thunderbirds at Toronto Marlies | 4:00 p.m. |
| December 4, 2021 | Charlotte Checkers at Wilkes-Barre/Scranton Penguins | 6:05 p.m. |
| December 4, 2021 | Manitoba Moose at Belleville Senators | 7:00 p.m. |
| December 4, 2021 | Providence Bruins at Bridgeport Islanders | 7:00 p.m. |
| December 4, 2021 | Milwaukee Admirals at Cleveland Monsters | 7:00 p.m. |
| December 4, 2021 | Rockford IceHogs at Grand Rapids Griffins | 7:00 p.m. |
| December 4, 2021 | Chicago Wolves at Iowa Wild | 7:00 p.m. |
| December 4, 2021 | Rochester Americans at Syracuse Crunch | 7:00 p.m. |
| December 4, 2021 | Hershey Bears at Lehigh Valley Phantoms | 7:05 p.m. |
| December 4, 2021 | Utica Comets at Hartford Wolf Pack | 7:30 p.m. |
| December 4, 2021 | San Diego Gulls at Stockton Heat | 9:00 p.m. |
| December 4, 2021 | Tucson Roadrunners at Colorado Eagles | 9:05 p.m. |
| December 4, 2021 | San Jose Barracuda at Abbotsford Canucks | 10:00 p.m. |
| December 4, 2021 | Ontario Reign at Bakersfield Condors | 10:00 p.m. |
| December 5, 2021 | Manitoba Moose at Belleville Senators | 3:00 p.m. |
| December 5, 2021 | Charlotte Checkers at Bridgeport Islanders | 3:00 p.m. |
| December 5, 2021 | Wilkes-Barre/Scranton Penguins at Hershey Bears | 3:00 p.m. |
| December 5, 2021 | Utica Comets at Providence Bruins | 3:05 p.m. |
| December 5, 2021 | Chicago Wolves at Iowa Wild | 4:00 p.m. |
| December 5, 2021 | Laval Rocket at Toronto Marlies | 4:00 p.m. |
| December 5, 2021 | San Jose Barracuda at Abbotsford Canucks | 7:00 p.m. |
| December 6, 2021 | Grand Rapids Griffins at Cleveland Monsters | 7:00 p.m. |
| December 7, 2021 | Ontario Reign at Bakersfield Condors | 1:30 p.m. |
| December 7, 2021 | San Jose Barracuda at Stockton Heat | 9:30 p.m. |
| December 8, 2021 | Belleville Senators at Hartford Wolf Pack | 7:00 p.m. |
| December 8, 2021 | Cleveland Monsters at Syracuse Crunch | 7:00 p.m. |
| December 8, 2021 | Utica Comets at Rochester Americans | 7:05 p.m. |
| December 8, 2021 | Hershey Bears at Wilkes-Barre/Scranton Penguins | 7:05 p.m. |
| December 8, 2021 | Manitoba Moose at Laval Rocket | 7:30 p.m. |
| December 8, 2021 | Iowa Wild at Rockford IceHogs | 8:00 p.m. |
| December 9, 2021 | Chicago Wolves at Texas Stars | 8:00 p.m. |
| December 10, 2021 | Syracuse Crunch at Charlotte Checkers | 7:00 p.m. |
| December 10, 2021 | Lehigh Valley Phantoms at Hartford Wolf Pack | 7:00 p.m. |
| December 10, 2021 | Cleveland Monsters at Utica Comets | 7:00 p.m. |
| December 10, 2021 | Belleville Senators at Providence Bruins | 7:05 p.m. |
| December 10, 2021 | Laval Rocket at Rochester Americans | 7:05 p.m. |
| December 10, 2021 | Toronto Marlies at Springfield Thunderbirds | 7:05 p.m. |
| December 10, 2021 | Grand Rapids Griffins at Manitoba Moose | 8:00 p.m. |
| December 10, 2021 | Iowa Wild at Milwaukee Admirals | 8:00 p.m. |
| December 10, 2021 | Henderson Silver Knights at Rockford IceHogs | 8:00 p.m. |
| December 10, 2021 | Stockton Heat at Tucson Roadrunners | 9:00 p.m. |
| December 10, 2021 | Bakersfield Condors at Colorado Eagles | 9:05 p.m. |
| December 10, 2021 | San Diego Gulls at Ontario Reign | 10:00 p.m. |
| December 11, 2021 | Abbotsford Canucks at San Jose Barracuda | 4:15 p.m. |
| December 11, 2021 | Syracuse Crunch at Charlotte Checkers | 6:00 p.m. |
| December 11, 2021 | Hershey Bears at Wilkes-Barre/Scranton Penguins | 6:05 p.m. |
| December 11, 2021 | Toronto Marlies at Bridgeport Islanders | 7:00 p.m. |
| December 11, 2021 | Grand Rapids Griffins at Manitoba Moose | 7:00 p.m. |
| December 11, 2021 | Iowa Wild at Milwaukee Admirals | 7:00 p.m. |
| December 11, 2021 | Henderson Silver Knights at Rockford IceHogs | 7:00 p.m. |
| December 11, 2021 | Cleveland Monsters at Lehigh Valley Phantoms | 7:05 p.m. |
| December 11, 2021 | Providence Bruins at Springfield Thunderbirds | 7:05 p.m. |
| December 11, 2021 | Chicago Wolves at Texas Stars | 8:00 p.m. |
| December 11, 2021 | Stockton Heat at Tucson Roadrunners | 9:00 p.m. |
| December 11, 2021 | Bakersfield Condors at Colorado Eagles | 9:05 p.m. |
| December 11, 2021 | Ontario Reign at San Diego Gulls | 10:00 p.m. |
| December 12, 2021 | Belleville Senators at Bridgeport Islanders | 3:00 p.m. |
| December 12, 2021 | Hartford Wolf Pack at Lehigh Valley Phantoms | 3:05 p.m. |
| December 12, 2021 | Toronto Marlies at Providence Bruins | 3:05 p.m. |
| December 12, 2021 | Springfield Thunderbirds at Wilkes-Barre/Scranton Penguins | 3:05 p.m. |
| December 12, 2021 | Laval Rocket at Hershey Bears | 5:00 p.m. |
| December 12, 2021 | Abbotsford Canucks at San Jose Barracuda | 6:00 p.m. |
| December 12, 2021 | Chicago Wolves at Texas Stars | 6:00 p.m. |
| December 14, 2021 | Rochester Americans at Charlotte Checkers | 7:00 p.m. |
| December 14, 2021 | Milwaukee Admirals at Iowa Wild | 8:00 p.m. |
| December 14, 2021 | Henderson Silver Knights at Tucson Roadrunners | 8:30 p.m. |
| December 15, 2021 | Rochester Americans at Charlotte Checkers | 7:00 p.m. |
| December 15, 2021 | Syracuse Crunch at Toronto Marlies | 7:00 p.m. |
| December 15, 2021 | Belleville Senators at Lehigh Valley Phantoms | 7:05 p.m. |
| December 15, 2021 | Henderson Silver Knights at Tucson Roadrunners | 8:30 p.m. |
| December 15, 2021 | Bakersfield Condors at Stockton Heat | 9:30 p.m. |
| December 15, 2021 | Abbotsford Canucks at San Diego Gulls | 10:00 p.m. |
| December 15, 2021 | Colorado Eagles at San Jose Barracuda | 10:00 p.m. |
| December 16, 2021 | Manitoba Moose at Chicago Wolves | 12:00 p.m. |
| December 16, 2021 | Utica Comets at Cleveland Monsters | 7:00 p.m. |
| December 17, 2021 | Utica Comets at Cleveland Monsters | 7:00 p.m. |
| December 17, 2021 | Lehigh Valley Phantoms at Hartford Wolf Pack | 7:00 p.m. |
| December 17, 2021 | Providence Bruins at Laval Rocket | 7:00 p.m. |
| December 17, 2021 | Belleville Senators at Syracuse Crunch | 7:00 p.m. |
| December 17, 2021 | Hershey Bears at Springfield Thunderbirds | 7:05 p.m. |
| December 17, 2021 | Manitoba Moose at Iowa Wild | 8:00 p.m. |
| December 17, 2021 | Chicago Wolves at Milwaukee Admirals | 8:00 p.m. |
| December 17, 2021 | Rockford IceHogs at Texas Stars | 8:00 p.m. |
| December 17, 2021 | San Jose Barracuda at Ontario Reign | 10:00 p.m. |
| December 17, 2021 | Bakersfield Condors at San Diego Gulls | 10:00 p.m. |
| December 17, 2021 | Colorado Eagles at Stockton Heat | 10:00 p.m. |
| December 18, 2021 | Bridgeport Islanders at Charlotte Checkers | 6:00 p.m. |
| December 18, 2021 | Providence Bruins at Belleville Senators | 7:00 p.m. |
| December 18, 2021 | Toronto Marlies at Grand Rapids Griffins | 7:00 p.m. |
| December 18, 2021 | Abbotsford Canucks at Henderson Silver Knights | 7:00 p.m. |
| December 18, 2021 | Wilkes-Barre/Scranton Penguins at Hershey Bears | 7:00 p.m. |
| December 18, 2021 | Manitoba Moose at Iowa Wild | 7:00 p.m. |
| December 18, 2021 | Laval Rocket at Syracuse Crunch | 7:00 p.m. |
| December 18, 2021 | Rochester Americans at Lehigh Valley Phantoms | 7:05 p.m. |
| December 18, 2021 | Hartford Wolf Pack at Springfield Thunderbirds | 7:05 p.m. |
| December 18, 2021 | Milwaukee Admirals at Chicago Wolves | 8:00 p.m. |
| December 18, 2021 | Rockford IceHogs at Texas Stars | 8:00 p.m. |
| December 18, 2021 | Tucson Roadrunners at Ontario Reign | 9:00 p.m. |
| December 18, 2021 | Colorado Eagles at Stockton Heat | 9:00 p.m. |
| December 18, 2021 | San Jose Barracuda at San Diego Gulls | 10:00 p.m. |
| December 19, 2021 | Bridgeport Islanders at Charlotte Checkers | 1:00 p.m. |
| December 19, 2021 | Springfield Thunderbirds at Hartford Wolf Pack | 3:00 p.m. |
| December 19, 2021 | Toronto Marlies at Grand Rapids Griffins | 4:00 p.m. |
| December 19, 2021 | Rochester Americans at Hershey Bears | 5:00 p.m. |
| December 19, 2021 | Abbotsford Canucks at Henderson Silver Knights | 7:00 p.m. |
| December 21, 2021 | Utica Comets at Belleville Senators | 7:00 p.m. |
| December 21, 2021 | Wilkes-Barre/Scranton Penguins at Toronto Marlies | 7:00 p.m. |
| December 21, 2021 | Milwaukee Admirals at Rockford IceHogs | 8:00 p.m. |
| December 21, 2021 | Manitoba Moose at Texas Stars | 8:00 p.m. |
| December 21, 2021 | San Jose Barracuda at Colorado Eagles | 9:05 p.m. |
| December 22, 2021 | Manitoba Moose at Texas Stars | 6:00 p.m. |
| December 22, 2021 | Chicago Wolves at Cleveland Monsters | 7:00 p.m. |
| December 22, 2021 | Milwaukee Admirals at Grand Rapids Griffins | 7:00 p.m. |
| December 22, 2021 | Bridgeport Islanders at Hartford Wolf Pack | 7:00 p.m. |
| December 22, 2021 | Lehigh Valley Phantoms at Hershey Bears | 7:00 p.m. |
| December 22, 2021 | Providence Bruins at Syracuse Crunch | 7:00 p.m. |
| December 22, 2021 | Wilkes-Barre/Scranton Penguins at Rochester Americans | 7:05 p.m. |
| December 22, 2021 | San Jose Barracuda at Colorado Eagles | 9:05 p.m. |
| December 22, 2021 | Tucson Roadrunners at Abbotsford Canucks | 10:00 p.m. |
| December 22, 2021 | Ontario Reign at Henderson Silver Knights | 10:00 p.m. |
| December 22, 2021 | Stockton Heat at San Diego Gulls | 10:00 p.m. |
| December 23, 2021 | Chicago Wolves at Cleveland Monsters | 7:00 p.m. |
| December 23, 2021 | Tucson Roadrunners at Abbotsford Canucks | 10:00 p.m. |
| December 26, 2021 | Belleville Senators at Toronto Marlies | 3:00 p.m. |
| December 27, 2021 | Grand Rapids Griffins at Cleveland Monsters | 7:00 p.m. |
| December 27, 2021 | Rockford IceHogs at Iowa Wild | 7:00 p.m. |
| December 27, 2021 | Utica Comets at Rochester Americans | 7:05 p.m. |
| December 27, 2021 | Hershey Bears at Wilkes-Barre/Scranton Penguins | 7:05 p.m. |
| December 27, 2021 | Ontario Reign at San Diego Gulls | 10:00 p.m. |
| December 27, 2021 | Bakersfield Condors at San Jose Barracuda | 10:00 p.m. |
| December 28, 2021 | Syracuse Crunch at Belleville Senators | 7:00 p.m. |
| December 28, 2021 | Springfield Thunderbirds at Bridgeport Islanders | 7:00 p.m. |
| December 28, 2021 | Providence Bruins at Toronto Marlies | 7:00 p.m. |
| December 29, 2021 | Utica Comets at Springfield Thunderbirds | 6:05 p.m. |
| December 29, 2021 | Hartford Wolf Pack at Bridgeport Islanders | 7:00 p.m. |
| December 29, 2021 | Wilkes-Barre/Scranton Penguins at Hershey Bears | 7:00 p.m. |
| December 29, 2021 | Colorado Eagles at Iowa Wild | 7:00 p.m. |
| December 29, 2021 | Cleveland Monsters at Lehigh Valley Phantoms | 7:05 p.m. |
| December 29, 2021 | Providence Bruins at Rochester Americans | 7:05 p.m. |
| December 29, 2021 | Syracuse Crunch at Laval Rocket | 7:30 p.m. |
| December 29, 2021 | Stockton Heat at San Jose Barracuda | 8:00 p.m. |
| December 29, 2021 | Ontario Reign at Bakersfield Condors | 9:30 p.m. |
| December 29, 2021 | Henderson Silver Knights at San Diego Gulls | 10:00 p.m. |
| December 30, 2021 | Toronto Marlies at Belleville Senators | 7:00 p.m. |
| December 30, 2021 | Rockford IceHogs at Milwaukee Admirals | 7:00 p.m. |
| December 30, 2021 | Abbotsford Canucks at Manitoba Moose | 8:00 p.m. |
| December 31, 2021 | Providence Bruins at Hartford Wolf Pack | 3:00 p.m. |
| December 31, 2021 | Colorado Eagles at Iowa Wild | 3:00 p.m. |
| December 31, 2021 | San Jose Barracuda at Stockton Heat | 4:00 p.m. |
| December 31, 2021 | Abbotsford Canucks at Manitoba Moose | 5:00 p.m. |
| December 31, 2021 | Lehigh Valley Phantoms at Utica Comets | 5:00 p.m. |
| December 31, 2021 | Cleveland Monsters at Wilkes-Barre/Scranton Penguins | 5:05 p.m. |
| December 31, 2021 | Milwaukee Admirals at Grand Rapids Griffins | 6:00 p.m. |
| December 31, 2021 | Chicago Wolves at Rockford IceHogs | 7:00 p.m. |
| December 31, 2021 | Charlotte Checkers at Texas Stars | 8:00 p.m. |
| December 31, 2021 | San Diego Gulls at Tucson Roadrunners | 8:00 p.m. |
| December 31, 2021 | Henderson Silver Knights at Ontario Reign | 10:00 p.m. |
| January 1, 2022 | Rochester Americans at Springfield Thunderbirds | 2:05 p.m. |
| January 1, 2022 | Belleville Senators at Toronto Marlies | 3:00 p.m. |
| January 1, 2022 | Cleveland Monsters at Wilkes-Barre/Scranton Penguins | 6:05 p.m. |
| January 1, 2022 | Grand Rapids Griffins at Milwaukee Admirals | 7:00 p.m. |
| January 1, 2022 | Rockford IceHogs at Chicago Wolves | 8:00 p.m. |
| January 1, 2022 | Bakersfield Condors at Henderson Silver Knights | 8:00 p.m. |
| January 1, 2022 | Charlotte Checkers at Texas Stars | 8:00 p.m. |
| January 2, 2022 | Rochester Americans at Hartford Wolf Pack | 3:00 p.m. |
| January 2, 2022 | Bridgeport Islanders at Hershey Bears | 3:00 p.m. |
| January 2, 2022 | Iowa Wild at Manitoba Moose | 3:00 p.m. |
| January 2, 2022 | Springfield Thunderbirds at Providence Bruins | 3:05 p.m. |
| January 2, 2022 | Grand Rapids Griffins at Chicago Wolves | 4:00 p.m. |
| January 2, 2022 | Stockton Heat at San Jose Barracuda | 4:00 p.m. |
| January 2, 2022 | San Diego Gulls at Tucson Roadrunners | 4:00 p.m. |
| January 2, 2022 | Bakersfield Condors at Ontario Reign | 6:00 p.m. |
| January 4, 2022 | Iowa Wild at Manitoba Moose | 8:00 p.m. |
| January 4, 2022 | Stockton Heat at Tucson Roadrunners | 8:30 p.m. |
| January 5, 2022 | Providence Bruins at Bridgeport Islanders | 7:00 p.m. |
| January 5, 2022 | Milwaukee Admirals at Grand Rapids Griffins | 7:00 p.m. |
| January 5, 2022 | Utica Comets at Toronto Marlies | 7:00 p.m. |
| January 5, 2022 | Belleville Senators at Rochester Americans | 7:05 p.m. |
| January 5, 2022 | Springfield Thunderbirds at Laval Rocket | 7:30 p.m. |
| January 5, 2022 | Stockton Heat at Tucson Roadrunners | 8:30 p.m. |
| January 5, 2022 | Bakersfield Condors at Abbotsford Canucks | 10:00 p.m. |
| January 5, 2022 | San Diego Gulls at Henderson Silver Knights | 10:00 p.m. |
| January 7, 2022 | Springfield Thunderbirds at Belleville Senators | 7:00 p.m. |
| January 7, 2022 | Iowa Wild at Grand Rapids Griffins | 7:00 p.m. |
| January 7, 2022 | Toronto Marlies at Laval Rocket | 7:00 p.m. |
| January 7, 2022 | Hershey Bears at Syracuse Crunch | 7:00 p.m. |
| January 7, 2022 | Wilkes-Barre/Scranton Penguins at Utica Comets | 7:00 p.m. |
| January 7, 2022 | Lehigh Valley Phantoms at Providence Bruins | 7:05 p.m. |
| January 7, 2022 | Hartford Wolf Pack at Rochester Americans | 7:05 p.m. |
| January 7, 2022 | Cleveland Monsters at Milwaukee Admirals | 8:00 p.m. |
| January 7, 2022 | Chicago Wolves at Rockford IceHogs | 8:00 p.m. |
| January 7, 2022 | Manitoba Moose at Texas Stars | 8:00 p.m. |
| January 7, 2022 | Bakersfield Condors at Abbotsford Canucks | 10:00 p.m. |
| January 7, 2022 | Stockton Heat at San Diego Gulls | 10:00 p.m. |
| January 7, 2022 | Henderson Silver Knights at San Jose Barracuda | 10:00 p.m. |
| January 8, 2022 | Toronto Marlies at Laval Rocket | 3:00 p.m. |
| January 8, 2022 | Springfield Thunderbirds at Belleville Senators | 7:00 p.m. |
| January 8, 2022 | Charlotte Checkers at Bridgeport Islanders | 7:00 p.m. |
| January 8, 2022 | Cleveland Monsters at Grand Rapids Griffins | 7:00 p.m. |
| January 8, 2022 | Wilkes-Barre/Scranton Penguins at Hershey Bears | 7:00 p.m. |
| January 8, 2022 | Rockford IceHogs at Milwaukee Admirals | 7:00 p.m. |
| January 8, 2022 | Rochester Americans at Syracuse Crunch | 7:00 p.m. |
| January 8, 2022 | Hartford Wolf Pack at Utica Comets | 7:00 p.m. |
| January 8, 2022 | Iowa Wild at Chicago Wolves | 8:00 p.m. |
| January 8, 2022 | Manitoba Moose at Texas Stars | 8:00 p.m. |
| January 8, 2022 | San Diego Gulls at Ontario Reign | 9:00 p.m. |
| January 8, 2022 | Colorado Eagles at Tucson Roadrunners | 9:00 p.m. |
| January 8, 2022 | Henderson Silver Knights at San Jose Barracuda | 10:00 p.m. |
| January 9, 2022 | Charlotte Checkers at Bridgeport Islanders | 3:00 p.m. |
| January 9, 2022 | Lehigh Valley Phantoms at Providence Bruins | 3:05 p.m. |
| January 9, 2022 | Cleveland Monsters at Chicago Wolves | 4:00 p.m. |
| January 9, 2022 | Wilkes-Barre/Scranton Penguins at Hershey Bears | 5:00 p.m. |
| January 9, 2022 | Stockton Heat at Ontario Reign | 6:00 p.m. |
| January 9, 2022 | Colorado Eagles at Tucson Roadrunners | 6:00 p.m. |
| January 9, 2022 | Bakersfield Condors at Abbotsford Canucks | 7:00 p.m. |
| January 10, 2022 | Bakersfield Condors at Abbotsford Canucks | 10:00 p.m. |
| January 11, 2022 | Iowa Wild at Rockford IceHogs | 8:00 p.m. |
| January 12, 2022 | Charlotte Checkers at Hartford Wolf Pack | 7:00 p.m. |
| January 12, 2022 | Bridgeport Islanders at Hershey Bears | 7:00 p.m. |
| January 12, 2022 | Belleville Senators at Toronto Marlies | 7:00 p.m. |
| January 12, 2022 | Utica Comets at Rochester Americans | 7:05 p.m. |
| January 12, 2022 | Syracuse Crunch at Laval Rocket | 7:30 p.m. |
| January 12, 2022 | Grand Rapids Griffins at Chicago Wolves | 8:00 p.m. |
| January 12, 2022 | Manitoba Moose at Milwaukee Admirals | 8:00 p.m. |
| January 12, 2022 | Stockton Heat at Henderson Silver Knights | 10:00 p.m. |
| January 12, 2022 | Tucson Roadrunners at San Jose Barracuda | 10:00 p.m. |
| January 14, 2022 | Manitoba Moose at Grand Rapids Griffins | 7:00 p.m. |
| January 14, 2022 | Chicago Wolves at Iowa Wild | 7:00 p.m. |
| January 14, 2022 | Syracuse Crunch at Utica Comets | 7:00 p.m. |
| January 14, 2022 | Hartford Wolf Pack at Providence Bruins | 7:05 p.m. |
| January 14, 2022 | Belleville Senators at Rochester Americans | 7:05 p.m. |
| January 14, 2022 | Laval Rocket at Springfield Thunderbirds | 7:05 p.m. |
| January 14, 2022 | Lehigh Valley Phantoms at Wilkes-Barre/Scranton Penguins | 7:05 p.m. |
| January 14, 2022 | Cleveland Monsters at Rockford IceHogs | 8:00 p.m. |
| January 14, 2022 | Milwaukee Admirals at Colorado Eagles | 9:05 p.m. |
| January 14, 2022 | Stockton Heat at Bakersfield Condors | 10:00 p.m. |
| January 14, 2022 | Henderson Silver Knights at Ontario Reign | 10:00 p.m. |
| January 14, 2022 | Abbotsford Canucks at San Diego Gulls | 10:00 p.m. |
| January 14, 2022 | Tucson Roadrunners at San Jose Barracuda | 10:00 p.m. |
| January 15, 2022 | Texas Stars at Charlotte Checkers | 6:00 p.m. |
| January 15, 2022 | Belleville Senators at Rochester Americans | 6:05 p.m. |
| January 15, 2022 | Manitoba Moose at Grand Rapids Griffins | 7:00 p.m. |
| January 15, 2022 | Toronto Marlies at Hershey Bears | 7:00 p.m. |
| January 15, 2022 | Chicago Wolves at Iowa Wild | 7:00 p.m. |
| January 15, 2022 | Cleveland Monsters at Rockford IceHogs | 7:00 p.m. |
| January 15, 2022 | Utica Comets at Syracuse Crunch | 7:00 p.m. |
| January 15, 2022 | Wilkes-Barre/Scranton Penguins at Lehigh Valley Phantoms | 7:05 p.m. |
| January 15, 2022 | Providence Bruins at Springfield Thunderbirds | 7:05 p.m. |
| January 15, 2022 | Laval Rocket at Hartford Wolf Pack | 7:30 p.m. |
| January 15, 2022 | Milwaukee Admirals at Colorado Eagles | 9:05 p.m. |
| January 15, 2022 | San Jose Barracuda at Bakersfield Condors | 10:00 p.m. |
| January 15, 2022 | Ontario Reign at Henderson Silver Knights | 10:00 p.m. |
| January 15, 2022 | Abbotsford Canucks at San Diego Gulls | 10:00 p.m. |
| January 15, 2022 | Tucson Roadrunners at Stockton Heat | 10:00 p.m. |
| January 16, 2022 | Texas Stars at Charlotte Checkers | 1:00 p.m. |
| January 16, 2022 | Toronto Marlies at Lehigh Valley Phantoms | 3:05 p.m. |
| January 16, 2022 | Bridgeport Islanders at Providence Bruins | 3:05 p.m. |
| January 16, 2022 | Hershey Bears at Wilkes-Barre/Scranton Penguins | 3:05 p.m. |
| January 17, 2022 | Belleville Senators at Syracuse Crunch | 1:00 p.m. |
| January 17, 2022 | Chicago Wolves at Rockford IceHogs | 2:00 p.m. |
| January 17, 2022 | Milwaukee Admirals at Iowa Wild | 3:00 p.m. |
| January 17, 2022 | Abbotsford Canucks at Ontario Reign | 6:00 p.m. |
| January 18, 2022 | Springfield Thunderbirds at Charlotte Checkers | 7:00 p.m. |
| January 18, 2022 | Grand Rapids Griffins at Cleveland Monsters | 7:00 p.m. |
| January 18, 2022 | San Diego Gulls at San Jose Barracuda | 10:00 p.m. |
| January 19, 2022 | Toronto Marlies at Hartford Wolf Pack | 7:00 p.m. |
| January 19, 2022 | Syracuse Crunch at Rochester Americans | 7:05 p.m. |
| January 19, 2022 | Lehigh Valley Phantoms at Wilkes-Barre/Scranton Penguins | 7:05 p.m. |
| January 19, 2022 | Utica Comets at Laval Rocket | 7:30 p.m. |
| January 19, 2022 | Texas Stars at Milwaukee Admirals | 8:00 p.m. |
| January 19, 2022 | Tucson Roadrunners at Bakersfield Condors | 9:30 p.m. |
| January 19, 2022 | San Diego Gulls at Stockton Heat | 9:30 p.m. |
| January 20, 2022 | Springfield Thunderbirds at Charlotte Checkers | 7:00 p.m. |
| January 21, 2022 | Rochester Americans at Cleveland Monsters | 7:00 p.m. |
| January 21, 2022 | Belleville Senators at Laval Rocket | 7:00 p.m. |
| January 21, 2022 | Utica Comets at Syracuse Crunch | 7:00 p.m. |
| January 21, 2022 | Bridgeport Islanders at Providence Bruins | 7:05 p.m. |
| January 21, 2022 | Toronto Marlies at Wilkes-Barre/Scranton Penguins | 7:05 p.m. |
| January 21, 2022 | Texas Stars at Rockford IceHogs | 8:00 p.m. |
| January 21, 2022 | Iowa Wild at Colorado Eagles | 9:05 p.m. |
| January 21, 2022 | Henderson Silver Knights at Stockton Heat | 10:00 p.m. |
| January 22, 2022 | Rochester Americans at Cleveland Monsters | 1:00 p.m. |
| January 22, 2022 | Chicago Wolves at Manitoba Moose | 3:00 p.m. |
| January 22, 2022 | Lehigh Valley Phantoms at Charlotte Checkers | 4:00 p.m. |
| January 22, 2022 | Toronto Marlies at Wilkes-Barre/Scranton Penguins | 6:05 p.m. |
| January 22, 2022 | Laval Rocket at Belleville Senators | 7:00 p.m. |
| January 22, 2022 | Providence Bruins at Bridgeport Islanders | 7:00 p.m. |
| January 22, 2022 | Milwaukee Admirals at Grand Rapids Griffins | 7:00 p.m. |
| January 22, 2022 | Hartford Wolf Pack at Hershey Bears | 7:00 p.m. |
| January 22, 2022 | Texas Stars at Rockford IceHogs | 7:00 p.m. |
| January 22, 2022 | Syracuse Crunch at Utica Comets | 7:00 p.m. |
| January 22, 2022 | Tucson Roadrunners at Ontario Reign | 9:00 p.m. |
| January 22, 2022 | Henderson Silver Knights at Stockton Heat | 9:00 p.m. |
| January 22, 2022 | Iowa Wild at Colorado Eagles | 9:05 p.m. |
| January 22, 2022 | San Diego Gulls at Abbotsford Canucks | 10:00 p.m. |
| January 22, 2022 | San Jose Barracuda at Bakersfield Condors | 10:00 p.m. |
| January 23, 2022 | Lehigh Valley Phantoms at Charlotte Checkers | 1:00 p.m. |
| January 23, 2022 | Springfield Thunderbirds at Bridgeport Islanders | 3:00 p.m. |
| January 23, 2022 | Hartford Wolf Pack at Hershey Bears | 3:00 p.m. |
| January 23, 2022 | Chicago Wolves at Manitoba Moose | 3:00 p.m. |
| January 23, 2022 | Tucson Roadrunners at Ontario Reign | 6:00 p.m. |
| January 23, 2022 | San Diego Gulls at Abbotsford Canucks | 7:00 p.m. |
| January 23, 2022 | Bakersfield Condors at San Jose Barracuda | 8:00 p.m. |
| January 25, 2022 | Wilkes-Barre/Scranton Penguins at Hershey Bears | 7:00 p.m. |
| January 26, 2022 | Ontario Reign at San Jose Barracuda | 1:00 p.m. |
| January 26, 2022 | Milwaukee Admirals at Grand Rapids Griffins | 7:00 p.m. |
| January 26, 2022 | Cleveland Monsters at Syracuse Crunch | 7:00 p.m. |
| January 26, 2022 | Providence Bruins at Utica Comets | 7:00 p.m. |
| January 26, 2022 | Texas Stars at Chicago Wolves | 8:00 p.m. |
| January 26, 2022 | Iowa Wild at Rockford IceHogs | 8:00 p.m. |
| January 26, 2022 | Bakersfield Condors at Tucson Roadrunners | 8:30 p.m. |
| January 26, 2022 | Colorado Eagles at San Diego Gulls | 10:00 p.m. |
| January 27, 2022 | Ontario Reign at San Jose Barracuda | 10:00 p.m. |
| January 28, 2022 | Toronto Marlies at Belleville Senators | 7:00 p.m. |
| January 28, 2022 | Wilkes-Barre/Scranton Penguins at Cleveland Monsters | 7:00 p.m. |
| January 28, 2022 | Providence Bruins at Hartford Wolf Pack | 7:00 p.m. |
| January 28, 2022 | Charlotte Checkers at Utica Comets | 7:00 p.m. |
| January 28, 2022 | Syracuse Crunch at Rochester Americans | 7:05 p.m. |
| January 28, 2022 | Lehigh Valley Phantoms at Springfield Thunderbirds | 7:05 p.m. |
| January 28, 2022 | Grand Rapids Griffins at Chicago Wolves | 8:00 p.m. |
| January 28, 2022 | San Diego Gulls at Iowa Wild | 8:00 p.m. |
| January 28, 2022 | Rockford IceHogs at Milwaukee Admirals | 8:00 p.m. |
| January 28, 2022 | Laval Rocket at Texas Stars | 8:00 p.m. |
| January 28, 2022 | Bakersfield Condors at Tucson Roadrunners | 9:00 p.m. |
| January 28, 2022 | Colorado Eagles at Henderson Silver Knights | 10:00 p.m. |
| January 29, 2022 | Abbotsford Canucks at Manitoba Moose | 3:00 p.m. |
| January 29, 2022 | Utica Comets at Rochester Americans | 6:05 p.m. |
| January 29, 2022 | Toronto Marlies at Belleville Senators | 7:00 p.m. |
| January 29, 2022 | Wilkes-Barre/Scranton Penguins at Cleveland Monsters | 7:00 p.m. |
| January 29, 2022 | Lehigh Valley Phantoms at Hartford Wolf Pack | 7:00 p.m. |
| January 29, 2022 | Bridgeport Islanders at Hershey Bears | 7:00 p.m. |
| January 29, 2022 | San Diego Gulls at Iowa Wild | 7:00 p.m. |
| January 29, 2022 | Grand Rapids Griffins at Milwaukee Admirals | 7:00 p.m. |
| January 29, 2022 | Charlotte Checkers at Syracuse Crunch | 7:00 p.m. |
| January 29, 2022 | Providence Bruins at Springfield Thunderbirds | 7:05 p.m. |
| January 29, 2022 | Rockford IceHogs at Chicago Wolves | 8:00 p.m. |
| January 29, 2022 | Laval Rocket at Texas Stars | 8:00 p.m. |
| January 29, 2022 | Ontario Reign at Stockton Heat | 9:00 p.m. |
| January 29, 2022 | Bakersfield Condors at Tucson Roadrunners | 9:00 p.m. |
| January 29, 2022 | Colorado Eagles at Henderson Silver Knights | 10:00 p.m. |
| January 30, 2022 | Abbotsford Canucks at Manitoba Moose | 3:00 p.m. |
| January 30, 2022 | Hershey Bears at Lehigh Valley Phantoms | 5:05 p.m. |
| February 2, 2022 | Lehigh Valley Phantoms at Bridgeport Islanders | 10:30 a.m. |
| February 2, 2022 | Syracuse Crunch at Belleville Senators | 7:00 p.m. |
| February 2, 2022 | Hartford Wolf Pack at Hershey Bears | 7:00 p.m. |
| February 2, 2022 | Laval Rocket at Utica Comets | 7:00 p.m. |
| February 2, 2022 | Charlotte Checkers at Rochester Americans | 7:05 p.m. |
| February 2, 2022 | Springfield Thunderbirds at Wilkes-Barre/Scranton Penguins | 7:05 p.m. |
| February 2, 2022 | Milwaukee Admirals at Rockford IceHogs | 8:00 p.m. |
| February 2, 2022 | San Jose Barracuda at Henderson Silver Knights | 10:00 p.m. |
| February 2, 2022 | Colorado Eagles at San Diego Gulls | 10:00 p.m. |
| February 3, 2022 | Toronto Marlies at Cleveland Monsters | 7:00 p.m. |
| February 3, 2022 | Stockton Heat at Abbotsford Canucks | 10:00 p.m. |
| February 3, 2022 | San Jose Barracuda at Henderson Silver Knights | 10:00 p.m. |
| February 4, 2022 | Syracuse Crunch at Belleville Senators | 7:00 p.m. |
| February 4, 2022 | Hershey Bears at Cleveland Monsters | 7:00 p.m. |
| February 4, 2022 | Ontario Reign at Grand Rapids Griffins | 7:00 p.m. |
| February 4, 2022 | Laval Rocket at Utica Comets | 7:00 p.m. |
| February 4, 2022 | Providence Bruins at Lehigh Valley Phantoms | 7:05 p.m. |
| February 4, 2022 | Charlotte Checkers at Rochester Americans | 7:05 p.m. |
| February 4, 2022 | Hartford Wolf Pack at Springfield Thunderbirds | 7:05 p.m. |
| February 4, 2022 | Bridgeport Islanders at Wilkes-Barre/Scranton Penguins | 7:05 p.m. |
| February 4, 2022 | Rockford IceHogs at Iowa Wild | 8:00 p.m. |
| February 4, 2022 | Texas Stars at Manitoba Moose | 8:00 p.m. |
| February 4, 2022 | Chicago Wolves at Milwaukee Admirals | 8:00 p.m. |
| February 4, 2022 | Stockton Heat at Abbotsford Canucks | 10:00 p.m. |
| February 4, 2022 | Colorado Eagles at Bakersfield Condors | 10:00 p.m. |
| February 4, 2022 | Tucson Roadrunners at San Diego Gulls | 10:00 p.m. |
| February 5, 2022 | Hershey Bears at Cleveland Monsters | 3:00 p.m. |
| February 5, 2022 | Rochester Americans at Toronto Marlies | 4:00 p.m. |
| February 5, 2022 | Providence Bruins at Wilkes-Barre/Scranton Penguins | 6:05 p.m. |
| February 5, 2022 | Laval Rocket at Belleville Senators | 7:00 p.m. |
| February 5, 2022 | Ontario Reign at Grand Rapids Griffins | 7:00 p.m. |
| February 5, 2022 | Texas Stars at Manitoba Moose | 7:00 p.m. |
| February 5, 2022 | Chicago Wolves at Milwaukee Admirals | 7:00 p.m. |
| February 5, 2022 | Iowa Wild at Rockford IceHogs | 7:00 p.m. |
| February 5, 2022 | Charlotte Checkers at Syracuse Crunch | 7:00 p.m. |
| February 5, 2022 | Springfield Thunderbirds at Utica Comets | 7:00 p.m. |
| February 5, 2022 | Bridgeport Islanders at Lehigh Valley Phantoms | 7:05 p.m. |
| February 5, 2022 | Colorado Eagles at Bakersfield Condors | 10:00 p.m. |
| February 5, 2022 | Tucson Roadrunners at San Diego Gulls | 10:00 p.m. |
| February 10, 2022 | Grand Rapids Griffins at Iowa Wild | 8:00 p.m. |
| February 11, 2022 | Bridgeport Islanders at Charlotte Checkers | 7:00 p.m. |
| February 11, 2022 | Springfield Thunderbirds at Hartford Wolf Pack | 7:00 p.m. |
| February 11, 2022 | Syracuse Crunch at Laval Rocket | 7:00 p.m. |
| February 11, 2022 | Cleveland Monsters at Utica Comets | 7:00 p.m. |
| February 11, 2022 | Hershey Bears at Lehigh Valley Phantoms | 7:05 p.m. |
| February 11, 2022 | Rochester Americans at Providence Bruins | 7:05 p.m. |
| February 11, 2022 | Belleville Senators at Wilkes-Barre/Scranton Penguins | 7:05 p.m. |
| February 11, 2022 | Grand Rapids Griffins at Iowa Wild | 8:00 p.m. |
| February 11, 2022 | Chicago Wolves at Rockford IceHogs | 8:00 p.m. |
| February 11, 2022 | Milwaukee Admirals at Texas Stars | 8:00 p.m. |
| February 11, 2022 | Tucson Roadrunners at Colorado Eagles | 9:05 p.m. |
| February 11, 2022 | Manitoba Moose at Abbotsford Canucks | 10:00 p.m. |
| February 11, 2022 | Henderson Silver Knights at Bakersfield Condors | 10:00 p.m. |
| February 11, 2022 | San Jose Barracuda at San Diego Gulls | 10:00 p.m. |
| February 11, 2022 | Ontario Reign at Stockton Heat | 10:00 p.m. |
| February 12, 2022 | Syracuse Crunch at Laval Rocket | 3:00 p.m. |
| February 12, 2022 | Bridgeport Islanders at Charlotte Checkers | 6:00 p.m. |
| February 12, 2022 | Rochester Americans at Hartford Wolf Pack | 7:00 p.m. |
| February 12, 2022 | Belleville Senators at Hershey Bears | 7:00 p.m. |
| February 12, 2022 | Cleveland Monsters at Utica Comets | 7:00 p.m. |
| February 12, 2022 | Wilkes-Barre/Scranton Penguins at Lehigh Valley Phantoms | 7:05 p.m. |
| February 12, 2022 | Providence Bruins at Springfield Thunderbirds | 7:05 p.m. |
| February 12, 2022 | Rockford IceHogs at Chicago Wolves | 8:00 p.m. |
| February 12, 2022 | Milwaukee Admirals at Texas Stars | 8:00 p.m. |
| February 12, 2022 | Ontario Reign at Stockton Heat | 9:00 p.m. |
| February 12, 2022 | Tucson Roadrunners at Colorado Eagles | 9:05 p.m. |
| February 12, 2022 | Manitoba Moose at Abbotsford Canucks | 10:00 p.m. |
| February 12, 2022 | Henderson Silver Knights at Bakersfield Condors | 10:00 p.m. |
| February 15, 2022 | Milwaukee Admirals at Chicago Wolves | 12:00 p.m. |
| February 15, 2022 | Rochester Americans at Bridgeport Islanders | 7:00 p.m. |
| February 15, 2022 | Wilkes-Barre/Scranton Penguins at Charlotte Checkers | 7:00 p.m. |
| February 15, 2022 | Grand Rapids Griffins at Texas Stars | 8:00 p.m. |
| February 15, 2022 | Henderson Silver Knights at Colorado Eagles | 9:05 p.m. |
| February 16, 2022 | Utica Comets at Toronto Marlies | 11:00 a.m. |
| February 16, 2022 | Laval Rocket at Belleville Senators | 7:00 p.m. |
| February 16, 2022 | Wilkes-Barre/Scranton Penguins at Charlotte Checkers | 7:00 p.m. |
| February 16, 2022 | Springfield Thunderbirds at Lehigh Valley Phantoms | 7:05 p.m. |
| February 16, 2022 | Rockford IceHogs at Milwaukee Admirals | 8:00 p.m. |
| February 16, 2022 | Grand Rapids Griffins at Texas Stars | 8:00 p.m. |
| February 16, 2022 | Henderson Silver Knights at Colorado Eagles | 9:05 p.m. |
| February 16, 2022 | Abbotsford Canucks at Bakersfield Condors | 9:30 p.m. |
| February 16, 2022 | San Diego Gulls at San Jose Barracuda | 10:00 p.m. |
| February 18, 2022 | Toronto Marlies at Belleville Senators | 7:00 p.m. |
| February 18, 2022 | Laval Rocket at Syracuse Crunch | 7:00 p.m. |
| February 18, 2022 | Rochester Americans at Utica Comets | 7:00 p.m. |
| February 18, 2022 | Hershey Bears at Providence Bruins | 7:05 p.m. |
| February 19, 2022 | Belleville Senators at Toronto Marlies | 4:00 p.m. |
| February 19, 2022 | Cleveland Monsters at Charlotte Checkers | 6:00 p.m. |
| February 19, 2022 | Springfield Thunderbirds at Wilkes-Barre/Scranton Penguins | 6:05 p.m. |
| February 19, 2022 | Hershey Bears at Bridgeport Islanders | 7:00 p.m. |
| February 19, 2022 | Rockford IceHogs at Grand Rapids Griffins | 7:00 p.m. |
| February 19, 2022 | Providence Bruins at Hartford Wolf Pack | 7:00 p.m. |
| February 19, 2022 | Rochester Americans at Syracuse Crunch | 7:00 p.m. |
| February 19, 2022 | Utica Comets at Lehigh Valley Phantoms | 7:05 p.m. |
| February 19, 2022 | Iowa Wild at Chicago Wolves | 8:00 p.m. |
| February 19, 2022 | San Jose Barracuda at Texas Stars | 8:00 p.m. |
| February 19, 2022 | Henderson Silver Knights at Tucson Roadrunners | 9:00 p.m. |
| February 19, 2022 | Abbotsford Canucks at Colorado Eagles | 9:05 p.m. |
| February 19, 2022 | Stockton Heat at Bakersfield Condors | 10:00 p.m. |
| February 19, 2022 | Ontario Reign at San Diego Gulls | 10:00 p.m. |
| February 20, 2022 | Cleveland Monsters at Charlotte Checkers | 1:00 p.m. |
| February 20, 2022 | Hartford Wolf Pack at Bridgeport Islanders | 3:00 p.m. |
| February 20, 2022 | Milwaukee Admirals at Manitoba Moose | 3:00 p.m. |
| February 20, 2022 | Springfield Thunderbirds at Lehigh Valley Phantoms | 3:05 p.m. |
| February 20, 2022 | Hershey Bears at Providence Bruins | 3:05 p.m. |
| February 20, 2022 | Laval Rocket at Rochester Americans | 3:05 p.m. |
| February 20, 2022 | Iowa Wild at Chicago Wolves | 4:00 p.m. |
| February 20, 2022 | Grand Rapids Griffins at Rockford IceHogs | 5:00 p.m. |
| February 20, 2022 | Abbotsford Canucks at Colorado Eagles | 5:05 p.m. |
| February 20, 2022 | San Diego Gulls at Ontario Reign | 6:00 p.m. |
| February 20, 2022 | San Jose Barracuda at Texas Stars | 6:00 p.m. |
| February 20, 2022 | Henderson Silver Knights at Tucson Roadrunners | 6:00 p.m. |
| February 20, 2022 | Bakersfield Condors at Stockton Heat | 8:00 p.m. |
| February 21, 2022 | Syracuse Crunch at Belleville Senators | 3:00 p.m. |
| February 21, 2022 | Milwaukee Admirals at Manitoba Moose | 3:00 p.m. |
| February 21, 2022 | Laval Rocket at Toronto Marlies | 3:00 p.m. |
| February 22, 2022 | Texas Stars at Iowa Wild | 8:00 p.m. |
| February 23, 2022 | Grand Rapids Griffins at Cleveland Monsters | 7:00 p.m. |
| February 23, 2022 | Laval Rocket at Toronto Marlies | 7:00 p.m. |
| February 23, 2022 | Bridgeport Islanders at Springfield Thunderbirds | 7:05 p.m. |
| February 23, 2022 | Lehigh Valley Phantoms at Wilkes-Barre/Scranton Penguins | 7:05 p.m. |
| February 23, 2022 | Milwaukee Admirals at Manitoba Moose | 8:00 p.m. |
| February 23, 2022 | Ontario Reign at Henderson Silver Knights | 10:00 p.m. |
| February 23, 2022 | Bakersfield Condors at San Jose Barracuda | 10:00 p.m. |
| February 24, 2022 | Texas Stars at Iowa Wild | 8:00 p.m. |
| February 25, 2022 | Lehigh Valley Phantoms at Cleveland Monsters | 7:00 p.m. |
| February 25, 2022 | Bakersfield Condors at Grand Rapids Griffins | 7:00 p.m. |
| February 25, 2022 | Belleville Senators at Laval Rocket | 7:00 p.m. |
| February 25, 2022 | Rochester Americans at Syracuse Crunch | 7:00 p.m. |
| February 25, 2022 | Hershey Bears at Utica Comets | 7:00 p.m. |
| February 25, 2022 | Charlotte Checkers at Providence Bruins | 7:05 p.m. |
| February 25, 2022 | Hartford Wolf Pack at Springfield Thunderbirds | 7:05 p.m. |
| February 25, 2022 | Rockford IceHogs at Iowa Wild | 8:00 p.m. |
| February 25, 2022 | Stockton Heat at Abbotsford Canucks | 10:00 p.m. |
| February 25, 2022 | San Diego Gulls at Henderson Silver Knights | 10:00 p.m. |
| February 26, 2022 | Lehigh Valley Phantoms at Cleveland Monsters | 1:00 p.m. |
| February 26, 2022 | Belleville Senators at Laval Rocket | 3:00 p.m. |
| February 26, 2022 | Chicago Wolves at Manitoba Moose | 3:00 p.m. |
| February 26, 2022 | Toronto Marlies at Rochester Americans | 3:05 p.m. |
| February 26, 2022 | San Diego Gulls at Henderson Silver Knights | 6:00 p.m. |
| February 26, 2022 | Wilkes-Barre/Scranton Penguins at Bridgeport Islanders | 7:00 p.m. |
| February 26, 2022 | Bakersfield Condors at Grand Rapids Griffins | 7:00 p.m. |
| February 26, 2022 | Providence Bruins at Hartford Wolf Pack | 7:00 p.m. |
| February 26, 2022 | Colorado Eagles at Milwaukee Admirals | 7:00 p.m. |
| February 26, 2022 | Texas Stars at Rockford IceHogs | 7:00 p.m. |
| February 26, 2022 | Utica Comets at Syracuse Crunch | 7:00 p.m. |
| February 26, 2022 | Charlotte Checkers at Springfield Thunderbirds | 7:05 p.m. |
| February 26, 2022 | Ontario Reign at Tucson Roadrunners | 9:00 p.m. |
| February 27, 2022 | Charlotte Checkers at Bridgeport Islanders | 3:00 p.m. |
| February 27, 2022 | Chicago Wolves at Manitoba Moose | 3:00 p.m. |
| February 27, 2022 | Hartford Wolf Pack at Providence Bruins | 3:05 p.m. |
| February 27, 2022 | Syracuse Crunch at Wilkes-Barre/Scranton Penguins | 3:05 p.m. |
| February 27, 2022 | Colorado Eagles at Milwaukee Admirals | 4:00 p.m. |
| February 27, 2022 | Rochester Americans at Toronto Marlies | 4:00 p.m. |
| February 27, 2022 | Utica Comets at Hershey Bears | 5:00 p.m. |
| February 27, 2022 | Texas Stars at Rockford IceHogs | 5:00 p.m. |
| February 27, 2022 | Ontario Reign at Tucson Roadrunners | 6:00 p.m. |
| February 27, 2022 | Stockton Heat at Abbotsford Canucks | 7:00 p.m. |
| February 28, 2022 | Cleveland Monsters at Laval Rocket | 7:30 p.m. |
| March 2, 2022 | Charlotte Checkers at Hershey Bears | 7:00 p.m. |
| March 2, 2022 | Abbotsford Canucks at Toronto Marlies | 7:00 p.m. |
| March 2, 2022 | Providence Bruins at Lehigh Valley Phantoms | 7:05 p.m. |
| March 2, 2022 | Syracuse Crunch at Rochester Americans | 7:05 p.m. |
| March 2, 2022 | Cleveland Monsters at Laval Rocket | 7:30 p.m. |
| March 2, 2022 | Texas Stars at Chicago Wolves | 8:00 p.m. |
| March 2, 2022 | San Diego Gulls at Colorado Eagles | 9:05 p.m. |
| March 2, 2022 | Tucson Roadrunners at Ontario Reign | 10:00 p.m. |
| March 3, 2022 | Rockford IceHogs at Manitoba Moose | 8:00 p.m. |
| March 4, 2022 | Rochester Americans at Belleville Senators | 7:00 p.m. |
| March 4, 2022 | Wilkes-Barre/Scranton Penguins at Bridgeport Islanders | 7:00 p.m. |
| March 4, 2022 | Iowa Wild at Grand Rapids Griffins | 7:00 p.m. |
| March 4, 2022 | Abbotsford Canucks at Laval Rocket | 7:00 p.m. |
| March 4, 2022 | Utica Comets at Syracuse Crunch | 7:00 p.m. |
| March 4, 2022 | Charlotte Checkers at Lehigh Valley Phantoms | 7:05 p.m. |
| March 4, 2022 | Hershey Bears at Springfield Thunderbirds | 7:05 p.m. |
| March 4, 2022 | Texas Stars at Milwaukee Admirals | 8:00 p.m. |
| March 4, 2022 | San Diego Gulls at Colorado Eagles | 9:05 p.m. |
| March 4, 2022 | Henderson Silver Knights at Ontario Reign | 10:00 p.m. |
| March 4, 2022 | Bakersfield Condors at Stockton Heat | 10:00 p.m. |
| March 5, 2022 | Abbotsford Canucks at Laval Rocket | 3:00 p.m. |
| March 5, 2022 | Rockford IceHogs at Manitoba Moose | 3:00 p.m. |
| March 5, 2022 | Rochester Americans at Belleville Senators | 7:00 p.m. |
| March 5, 2022 | Wilkes-Barre/Scranton Penguins at Bridgeport Islanders | 7:00 p.m. |
| March 5, 2022 | Toronto Marlies at Cleveland Monsters | 7:00 p.m. |
| March 5, 2022 | Iowa Wild at Grand Rapids Griffins | 7:00 p.m. |
| March 5, 2022 | Utica Comets at Syracuse Crunch | 7:00 p.m. |
| March 5, 2022 | Charlotte Checkers at Lehigh Valley Phantoms | 7:05 p.m. |
| March 5, 2022 | Providence Bruins at Springfield Thunderbirds | 7:05 p.m. |
| March 5, 2022 | Hershey Bears at Hartford Wolf Pack | 7:30 p.m. |
| March 5, 2022 | Texas Stars at Chicago Wolves | 8:00 p.m. |
| March 5, 2022 | Henderson Silver Knights at Ontario Reign | 9:00 p.m. |
| March 5, 2022 | San Jose Barracuda at Stockton Heat | 9:00 p.m. |
| March 5, 2022 | San Diego Gulls at Colorado Eagles | 9:05 p.m. |
| March 5, 2022 | Tucson Roadrunners at Bakersfield Condors | 10:00 p.m. |
| March 6, 2022 | Bridgeport Islanders at Hartford Wolf Pack | 3:00 p.m. |
| March 6, 2022 | Wilkes-Barre/Scranton Penguins at Providence Bruins | 3:05 p.m. |
| March 6, 2022 | Iowa Wild at Chicago Wolves | 4:00 p.m. |
| March 6, 2022 | Grand Rapids Griffins at Milwaukee Admirals | 6:00 p.m. |
| March 6, 2022 | Tucson Roadrunners at San Jose Barracuda | 8:00 p.m. |
| March 9, 2022 | Abbotsford Canucks at Toronto Marlies | 11:00 a.m. |
| March 9, 2022 | Iowa Wild at Milwaukee Admirals | 11:30 a.m. |
| March 9, 2022 | Chicago Wolves at Grand Rapids Griffins | 7:00 p.m. |
| March 9, 2022 | Syracuse Crunch at Utica Comets | 7:00 p.m. |
| March 9, 2022 | Springfield Thunderbirds at Providence Bruins | 7:05 p.m. |
| March 9, 2022 | Laval Rocket at Rochester Americans | 7:05 p.m. |
| March 9, 2022 | Hershey Bears at Wilkes-Barre/Scranton Penguins | 7:05 p.m. |
| March 9, 2022 | San Diego Gulls at Stockton Heat | 9:30 p.m. |
| March 9, 2022 | San Jose Barracuda at Ontario Reign | 10:00 p.m. |
| March 11, 2022 | Hershey Bears at Bridgeport Islanders | 7:00 p.m. |
| March 11, 2022 | Springfield Thunderbirds at Charlotte Checkers | 7:00 p.m. |
| March 11, 2022 | Cleveland Monsters at Grand Rapids Griffins | 7:00 p.m. |
| March 11, 2022 | Toronto Marlies at Utica Comets | 7:00 p.m. |
| March 11, 2022 | Laval Rocket at Lehigh Valley Phantoms | 7:05 p.m. |
| March 11, 2022 | Syracuse Crunch at Rochester Americans | 7:05 p.m. |
| March 11, 2022 | Belleville Senators at Manitoba Moose | 8:00 p.m. |
| March 11, 2022 | Rockford IceHogs at Milwaukee Admirals | 8:00 p.m. |
| March 11, 2022 | Tucson Roadrunners at Texas Stars | 8:00 p.m. |
| March 11, 2022 | Colorado Eagles at Abbotsford Canucks | 10:00 p.m. |
| March 11, 2022 | San Diego Gulls at Bakersfield Condors | 10:00 p.m. |
| March 11, 2022 | Stockton Heat at San Jose Barracuda | 10:00 p.m. |
| March 12, 2022 | Springfield Thunderbirds at Charlotte Checkers | 6:00 p.m. |
| March 12, 2022 | Laval Rocket at Wilkes-Barre/Scranton Penguins | 6:05 p.m. |
| March 12, 2022 | Henderson Silver Knights at Iowa Wild | 7:00 p.m. |
| March 12, 2022 | Belleville Senators at Manitoba Moose | 7:00 p.m. |
| March 12, 2022 | Chicago Wolves at Milwaukee Admirals | 7:00 p.m. |
| March 12, 2022 | Toronto Marlies at Syracuse Crunch | 7:00 p.m. |
| March 12, 2022 | Rochester Americans at Utica Comets | 7:00 p.m. |
| March 12, 2022 | Hartford Wolf Pack at Lehigh Valley Phantoms | 7:05 p.m. |
| March 12, 2022 | Bridgeport Islanders at Providence Bruins | 7:05 p.m. |
| March 12, 2022 | Tucson Roadrunners at Texas Stars | 8:00 p.m. |
| March 12, 2022 | San Jose Barracuda at Stockton Heat | 9:00 p.m. |
| March 12, 2022 | Ontario Reign at San Diego Gulls | 10:00 p.m. |
| March 13, 2022 | Rockford IceHogs at Cleveland Monsters | 3:00 p.m. |
| March 13, 2022 | Bridgeport Islanders at Providence Bruins | 3:05 p.m. |
| March 13, 2022 | Hartford Wolf Pack at Wilkes-Barre/Scranton Penguins | 3:05 p.m. |
| March 13, 2022 | Grand Rapids Griffins at Chicago Wolves | 4:00 p.m. |
| March 13, 2022 | Henderson Silver Knights at Iowa Wild | 4:00 p.m. |
| March 13, 2022 | Lehigh Valley Phantoms at Hershey Bears | 5:00 p.m. |
| March 13, 2022 | Colorado Eagles at Abbotsford Canucks | 7:00 p.m. |
| March 15, 2022 | Rockford IceHogs at Cleveland Monsters | 7:00 p.m. |
| March 15, 2022 | Manitoba Moose at Abbotsford Canucks | 10:00 p.m. |
| March 16, 2022 | Bridgeport Islanders at Springfield Thunderbirds | 10:35 a.m. |
| March 16, 2022 | Texas Stars at Grand Rapids Griffins | 7:00 p.m. |
| March 16, 2022 | Hartford Wolf Pack at Syracuse Crunch | 7:00 p.m. |
| March 16, 2022 | Milwaukee Admirals at Chicago Wolves | 8:00 p.m. |
| March 16, 2022 | San Jose Barracuda at Tucson Roadrunners | 8:30 p.m. |
| March 16, 2022 | Bakersfield Condors at Stockton Heat | 9:30 p.m. |
| March 16, 2022 | Manitoba Moose at Abbotsford Canucks | 10:00 p.m. |
| March 16, 2022 | Henderson Silver Knights at San Diego Gulls | 10:00 p.m. |
| March 17, 2022 | Hershey Bears at Toronto Marlies | 1:30 p.m. |
| March 17, 2022 | Providence Bruins at Charlotte Checkers | 7:00 p.m. |
| March 18, 2022 | Hershey Bears at Belleville Senators | 7:00 p.m. |
| March 18, 2022 | Syracuse Crunch at Bridgeport Islanders | 7:00 p.m. |
| March 18, 2022 | Texas Stars at Grand Rapids Griffins | 7:00 p.m. |
| March 18, 2022 | Hartford Wolf Pack at Laval Rocket | 7:00 p.m. |
| March 18, 2022 | Cleveland Monsters at Rochester Americans | 7:05 p.m. |
| March 18, 2022 | Lehigh Valley Phantoms at Springfield Thunderbirds | 7:05 p.m. |
| March 18, 2022 | Utica Comets at Wilkes-Barre/Scranton Penguins | 7:05 p.m. |
| March 18, 2022 | San Jose Barracuda at Tucson Roadrunners | 9:00 p.m. |
| March 18, 2022 | Stockton Heat at Colorado Eagles | 9:05 p.m. |
| March 18, 2022 | Bakersfield Condors at Ontario Reign | 10:00 p.m. |
| March 18, 2022 | Henderson Silver Knights at San Diego Gulls | 10:00 p.m. |
| March 19, 2022 | Hershey Bears at Laval Rocket | 3:00 p.m. |
| March 19, 2022 | Chicago Wolves at Toronto Marlies | 4:00 p.m. |
| March 19, 2022 | Providence Bruins at Charlotte Checkers | 6:00 p.m. |
| March 19, 2022 | Cleveland Monsters at Rochester Americans | 6:05 p.m. |
| March 19, 2022 | Syracuse Crunch at Wilkes-Barre/Scranton Penguins | 6:05 p.m. |
| March 19, 2022 | Hartford Wolf Pack at Belleville Senators | 7:00 p.m. |
| March 19, 2022 | Utica Comets at Bridgeport Islanders | 7:00 p.m. |
| March 19, 2022 | Manitoba Moose at Iowa Wild | 7:00 p.m. |
| March 19, 2022 | Texas Stars at Milwaukee Admirals | 7:00 p.m. |
| March 19, 2022 | Grand Rapids Griffins at Rockford IceHogs | 7:00 p.m. |
| March 19, 2022 | Lehigh Valley Phantoms at Springfield Thunderbirds | 7:05 p.m. |
| March 19, 2022 | San Jose Barracuda at Tucson Roadrunners | 9:00 p.m. |
| March 19, 2022 | Stockton Heat at Colorado Eagles | 9:05 p.m. |
| March 19, 2022 | Abbotsford Canucks at Bakersfield Condors | 10:00 p.m. |
| March 19, 2022 | San Diego Gulls at Henderson Silver Knights | 10:00 p.m. |
| March 20, 2022 | Providence Bruins at Charlotte Checkers | 1:00 p.m. |
| March 20, 2022 | Chicago Wolves at Toronto Marlies | 4:00 p.m. |
| March 20, 2022 | Milwaukee Admirals at Rockford IceHogs | 5:00 p.m. |
| March 20, 2022 | Wilkes-Barre/Scranton Penguins at Lehigh Valley Phantoms | 5:05 p.m. |
| March 20, 2022 | Abbotsford Canucks at Ontario Reign | 8:00 p.m. |
| March 21, 2022 | Cleveland Monsters at Utica Comets | 7:00 p.m. |
| March 21, 2022 | Manitoba Moose at Iowa Wild | 8:00 p.m. |
| March 22, 2022 | Texas Stars at Chicago Wolves | 8:00 p.m. |
| March 22, 2022 | Grand Rapids Griffins at Ontario Reign | 10:00 p.m. |
| March 23, 2022 | Springfield Thunderbirds at Hartford Wolf Pack | 7:00 p.m. |
| March 23, 2022 | Lehigh Valley Phantoms at Hershey Bears | 7:00 p.m. |
| March 23, 2022 | Cleveland Monsters at Syracuse Crunch | 7:00 p.m. |
| March 23, 2022 | Wilkes-Barre/Scranton Penguins at Toronto Marlies | 7:00 p.m. |
| March 23, 2022 | Bridgeport Islanders at Utica Comets | 7:00 p.m. |
| March 23, 2022 | Manitoba Moose at Rockford IceHogs | 8:00 p.m. |
| March 23, 2022 | Colorado Eagles at Bakersfield Condors | 9:30 p.m. |
| March 23, 2022 | Tucson Roadrunners at San Diego Gulls | 10:00 p.m. |
| March 24, 2022 | Abbotsford Canucks at San Jose Barracuda | 10:00 p.m. |
| March 25, 2022 | Wilkes-Barre/Scranton Penguins at Belleville Senators | 7:00 p.m. |
| March 25, 2022 | Charlotte Checkers at Cleveland Monsters | 7:00 p.m. |
| March 25, 2022 | Springfield Thunderbirds at Hartford Wolf Pack | 7:00 p.m. |
| March 25, 2022 | Lehigh Valley Phantoms at Laval Rocket | 7:00 p.m. |
| March 25, 2022 | Syracuse Crunch at Utica Comets | 7:00 p.m. |
| March 25, 2022 | Hershey Bears at Providence Bruins | 7:05 p.m. |
| March 25, 2022 | Toronto Marlies at Rochester Americans | 7:05 p.m. |
| March 25, 2022 | Manitoba Moose at Chicago Wolves | 8:00 p.m. |
| March 25, 2022 | Rockford IceHogs at Iowa Wild | 8:00 p.m. |
| March 25, 2022 | Milwaukee Admirals at Texas Stars | 8:00 p.m. |
| March 25, 2022 | Grand Rapids Griffins at Bakersfield Condors | 10:00 p.m. |
| March 25, 2022 | Tucson Roadrunners at Henderson Silver Knights | 10:00 p.m. |
| March 25, 2022 | Abbotsford Canucks at Stockton Heat | 10:00 p.m. |
| March 26, 2022 | Wilkes-Barre/Scranton Penguins at Laval Rocket | 3:00 p.m. |
| March 26, 2022 | Bridgeport Islanders at Toronto Marlies | 4:00 p.m. |
| March 26, 2022 | Colorado Eagles at San Jose Barracuda | 4:15 p.m. |
| March 26, 2022 | Tucson Roadrunners at Henderson Silver Knights | 6:00 p.m. |
| March 26, 2022 | Lehigh Valley Phantoms at Belleville Senators | 7:00 p.m. |
| March 26, 2022 | Hershey Bears at Hartford Wolf Pack | 7:00 p.m. |
| March 26, 2022 | Manitoba Moose at Rockford IceHogs | 7:00 p.m. |
| March 26, 2022 | Rochester Americans at Syracuse Crunch | 7:00 p.m. |
| March 26, 2022 | Springfield Thunderbirds at Providence Bruins | 7:05 p.m. |
| March 26, 2022 | Milwaukee Admirals at Texas Stars | 8:00 p.m. |
| March 26, 2022 | Grand Rapids Griffins at Bakersfield Condors | 10:00 p.m. |
| March 26, 2022 | Ontario Reign at San Diego Gulls | 10:00 p.m. |
| March 27, 2022 | Charlotte Checkers at Cleveland Monsters | 3:00 p.m. |
| March 27, 2022 | Utica Comets at Providence Bruins | 3:05 p.m. |
| March 27, 2022 | Bridgeport Islanders at Rochester Americans | 3:05 p.m. |
| March 27, 2022 | Chicago Wolves at Iowa Wild | 4:00 p.m. |
| March 27, 2022 | Grand Rapids Griffins at Ontario Reign | 6:00 p.m. |
| March 27, 2022 | Stockton Heat at San Diego Gulls | 8:00 p.m. |
| March 28, 2022 | Colorado Eagles at San Jose Barracuda | 10:00 p.m. |
| March 29, 2022 | Laval Rocket at Manitoba Moose | 8:00 p.m. |
| March 29, 2022 | Milwaukee Admirals at Rockford IceHogs | 8:00 p.m. |
| March 29, 2022 | Toronto Marlies at Abbotsford Canucks | 10:00 p.m. |
| March 30, 2022 | Ontario Reign at San Jose Barracuda | 1:00 p.m. |
| March 30, 2022 | Utica Comets at Rochester Americans | 7:05 p.m. |
| March 30, 2022 | Hartford Wolf Pack at Wilkes-Barre/Scranton Penguins | 7:05 p.m. |
| March 30, 2022 | Laval Rocket at Manitoba Moose | 8:00 p.m. |
| March 30, 2022 | Colorado Eagles at Stockton Heat | 9:30 p.m. |
| March 30, 2022 | Toronto Marlies at Abbotsford Canucks | 10:00 p.m. |
| April 1, 2022 | Hershey Bears at Charlotte Checkers | 7:00 p.m. |
| April 1, 2022 | Rochester Americans at Cleveland Monsters | 7:00 p.m. |
| April 1, 2022 | Texas Stars at Grand Rapids Griffins | 7:00 p.m. |
| April 1, 2022 | Belleville Senators at Hartford Wolf Pack | 7:00 p.m. |
| April 1, 2022 | Syracuse Crunch at Utica Comets | 7:00 p.m. |
| April 1, 2022 | Wilkes-Barre/Scranton Penguins at Lehigh Valley Phantoms | 7:05 p.m. |
| April 1, 2022 | Springfield Thunderbirds at Providence Bruins | 7:05 p.m. |
| April 1, 2022 | Toronto Marlies at Manitoba Moose | 8:00 p.m. |
| April 1, 2022 | Chicago Wolves at Milwaukee Admirals | 8:00 p.m. |
| April 1, 2022 | Rockford IceHogs at Tucson Roadrunners | 9:00 p.m. |
| April 1, 2022 | Henderson Silver Knights at Bakersfield Condors | 10:00 p.m. |
| April 1, 2022 | Colorado Eagles at Ontario Reign | 10:00 p.m. |
| April 1, 2022 | Iowa Wild at San Diego Gulls | 10:00 p.m. |
| April 2, 2022 | Hershey Bears at Charlotte Checkers | 6:00 p.m. |
| April 2, 2022 | Belleville Senators at Springfield Thunderbirds | 6:05 p.m. |
| April 2, 2022 | Bridgeport Islanders at Wilkes-Barre/Scranton Penguins | 6:05 p.m. |
| April 2, 2022 | Rochester Americans at Cleveland Monsters | 7:00 p.m. |
| April 2, 2022 | Texas Stars at Grand Rapids Griffins | 7:00 p.m. |
| April 2, 2022 | Syracuse Crunch at Hartford Wolf Pack | 7:00 p.m. |
| April 2, 2022 | Utica Comets at Lehigh Valley Phantoms | 7:05 p.m. |
| April 2, 2022 | Milwaukee Admirals at Chicago Wolves | 8:00 p.m. |
| April 2, 2022 | Colorado Eagles at Ontario Reign | 9:00 p.m. |
| April 2, 2022 | San Jose Barracuda at Stockton Heat | 9:00 p.m. |
| April 2, 2022 | Rockford IceHogs at Tucson Roadrunners | 9:00 p.m. |
| April 2, 2022 | Laval Rocket at Abbotsford Canucks | 10:00 p.m. |
| April 2, 2022 | Bakersfield Condors at Henderson Silver Knights | 10:00 p.m. |
| April 2, 2022 | Iowa Wild at San Diego Gulls | 10:00 p.m. |
| April 3, 2022 | Belleville Senators at Springfield Thunderbirds | 2:05 p.m. |
| April 3, 2022 | Lehigh Valley Phantoms at Bridgeport Islanders | 3:00 p.m. |
| April 3, 2022 | Toronto Marlies at Manitoba Moose | 3:00 p.m. |
| April 3, 2022 | Texas Stars at Chicago Wolves | 4:00 p.m. |
| April 3, 2022 | Syracuse Crunch at Providence Bruins | 4:05 p.m. |
| April 3, 2022 | Grand Rapids Griffins at Milwaukee Admirals | 6:00 p.m. |
| April 3, 2022 | Stockton Heat at San Jose Barracuda | 6:00 p.m. |
| April 3, 2022 | Laval Rocket at Abbotsford Canucks | 7:00 p.m. |
| April 4, 2022 | Rockford IceHogs at Henderson Silver Knights | 10:00 p.m. |
| April 5, 2022 | Hershey Bears at Bridgeport Islanders | 10:30 a.m. |
| April 5, 2022 | Iowa Wild at Tucson Roadrunners | 8:30 p.m. |
| April 5, 2022 | Rockford IceHogs at Henderson Silver Knights | 10:00 p.m. |
| April 6, 2022 | Syracuse Crunch at Toronto Marlies | 11:00 a.m. |
| April 6, 2022 | Manitoba Moose at Milwaukee Admirals | 11:30 a.m. |
| April 6, 2022 | Texas Stars at Chicago Wolves | 12:00 p.m. |
| April 6, 2022 | Cleveland Monsters at Grand Rapids Griffins | 7:00 p.m. |
| April 6, 2022 | Belleville Senators at Utica Comets | 7:00 p.m. |
| April 6, 2022 | Lehigh Valley Phantoms at Wilkes-Barre/Scranton Penguins | 7:05 p.m. |
| April 6, 2022 | Rochester Americans at Laval Rocket | 7:30 p.m. |
| April 6, 2022 | Iowa Wild at Tucson Roadrunners | 8:30 p.m. |
| April 6, 2022 | San Jose Barracuda at Bakersfield Condors | 9:30 p.m. |
| April 7, 2022 | Hartford Wolf Pack at Charlotte Checkers | 7:00 p.m. |
| April 8, 2022 | Utica Comets at Belleville Senators | 7:00 p.m. |
| April 8, 2022 | Providence Bruins at Bridgeport Islanders | 7:00 p.m. |
| April 8, 2022 | Hartford Wolf Pack at Charlotte Checkers | 7:00 p.m. |
| April 8, 2022 | Rochester Americans at Laval Rocket | 7:00 p.m. |
| April 8, 2022 | Springfield Thunderbirds at Syracuse Crunch | 7:00 p.m. |
| April 8, 2022 | Hershey Bears at Lehigh Valley Phantoms | 7:05 p.m. |
| April 8, 2022 | Manitoba Moose at Milwaukee Admirals | 8:00 p.m. |
| April 8, 2022 | Bakersfield Condors at Colorado Eagles | 9:05 p.m. |
| April 8, 2022 | San Diego Gulls at Abbotsford Canucks | 10:00 p.m. |
| April 8, 2022 | Ontario Reign at Stockton Heat | 10:00 p.m. |
| April 9, 2022 | Utica Comets at Laval Rocket | 4:00 p.m. |
| April 9, 2022 | Grand Rapids Griffins at Toronto Marlies | 4:00 p.m. |
| April 9, 2022 | Rochester Americans at Belleville Senators | 7:00 p.m. |
| April 9, 2022 | Springfield Thunderbirds at Hershey Bears | 7:00 p.m. |
| April 9, 2022 | Cleveland Monsters at Milwaukee Admirals | 7:00 p.m. |
| April 9, 2022 | Tucson Roadrunners at Rockford IceHogs | 7:00 p.m. |
| April 9, 2022 | Wilkes-Barre/Scranton Penguins at Syracuse Crunch | 7:00 p.m. |
| April 9, 2022 | Bridgeport Islanders at Providence Bruins | 7:05 p.m. |
| April 9, 2022 | Manitoba Moose at Chicago Wolves | 8:00 p.m. |
| April 9, 2022 | Iowa Wild at Texas Stars | 8:00 p.m. |
| April 9, 2022 | Bakersfield Condors at Colorado Eagles | 9:05 p.m. |
| April 9, 2022 | San Diego Gulls at Abbotsford Canucks | 10:00 p.m. |
| April 9, 2022 | Henderson Silver Knights at San Jose Barracuda | 10:00 p.m. |
| April 10, 2022 | Hartford Wolf Pack at Charlotte Checkers | 1:00 p.m. |
| April 10, 2022 | Lehigh Valley Phantoms at Bridgeport Islanders | 3:00 p.m. |
| April 10, 2022 | Cleveland Monsters at Chicago Wolves | 4:00 p.m. |
| April 10, 2022 | Grand Rapids Griffins at Toronto Marlies | 4:00 p.m. |
| April 10, 2022 | Henderson Silver Knights at San Jose Barracuda | 4:15 p.m. |
| April 10, 2022 | Springfield Thunderbirds at Hershey Bears | 5:00 p.m. |
| April 10, 2022 | Tucson Roadrunners at Rockford IceHogs | 5:00 p.m. |
| April 10, 2022 | Stockton Heat at Ontario Reign | 6:00 p.m. |
| April 10, 2022 | Iowa Wild at Texas Stars | 6:00 p.m. |
| April 13, 2022 | Hartford Wolf Pack at Belleville Senators | 7:00 p.m. |
| April 13, 2022 | Cleveland Monsters at Grand Rapids Griffins | 7:00 p.m. |
| April 13, 2022 | Hershey Bears at Lehigh Valley Phantoms | 7:05 p.m. |
| April 13, 2022 | Laval Rocket at Rochester Americans | 7:05 p.m. |
| April 13, 2022 | Syracuse Crunch at Springfield Thunderbirds | 7:05 p.m. |
| April 13, 2022 | Milwaukee Admirals at Iowa Wild | 8:00 p.m. |
| April 13, 2022 | Chicago Wolves at Texas Stars | 8:00 p.m. |
| April 13, 2022 | Stockton Heat at Henderson Silver Knights | 10:00 p.m. |
| April 13, 2022 | Bakersfield Condors at San Jose Barracuda | 10:00 p.m. |
| April 15, 2022 | Rockford IceHogs at Manitoba Moose | 3:00 p.m. |
| April 15, 2022 | Laval Rocket at Cleveland Monsters | 7:00 p.m. |
| April 15, 2022 | Iowa Wild at Grand Rapids Griffins | 7:00 p.m. |
| April 15, 2022 | Hartford Wolf Pack at Toronto Marlies | 7:00 p.m. |
| April 15, 2022 | Syracuse Crunch at Utica Comets | 7:00 p.m. |
| April 15, 2022 | Bridgeport Islanders at Lehigh Valley Phantoms | 7:05 p.m. |
| April 15, 2022 | Charlotte Checkers at Springfield Thunderbirds | 7:05 p.m. |
| April 15, 2022 | Hershey Bears at Wilkes-Barre/Scranton Penguins | 7:05 p.m. |
| April 15, 2022 | Chicago Wolves at Texas Stars | 8:00 p.m. |
| April 15, 2022 | Colorado Eagles at Tucson Roadrunners | 9:00 p.m. |
| April 15, 2022 | Stockton Heat at Henderson Silver Knights | 10:00 p.m. |
| April 15, 2022 | San Diego Gulls at Ontario Reign | 10:00 p.m. |
| April 15, 2022 | Abbotsford Canucks at San Jose Barracuda | 10:00 p.m. |
| April 16, 2022 | Rockford IceHogs at Manitoba Moose | 3:00 p.m. |
| April 16, 2022 | Charlotte Checkers at Springfield Thunderbirds | 6:05 p.m. |
| April 16, 2022 | Bridgeport Islanders at Wilkes-Barre/Scranton Penguins | 6:05 p.m. |
| April 16, 2022 | Laval Rocket at Cleveland Monsters | 7:00 p.m. |
| April 16, 2022 | Stockton Heat at Henderson Silver Knights | 7:00 p.m. |
| April 16, 2022 | Iowa Wild at Milwaukee Admirals | 7:00 p.m. |
| April 16, 2022 | Toronto Marlies at Syracuse Crunch | 7:00 p.m. |
| April 16, 2022 | Belleville Senators at Utica Comets | 7:00 p.m. |
| April 16, 2022 | Providence Bruins at Lehigh Valley Phantoms | 7:05 p.m. |
| April 16, 2022 | Hartford Wolf Pack at Rochester Americans | 7:05 p.m. |
| April 16, 2022 | Chicago Wolves at Texas Stars | 8:00 p.m. |
| April 16, 2022 | Colorado Eagles at Tucson Roadrunners | 9:00 p.m. |
| April 16, 2022 | Abbotsford Canucks at Bakersfield Condors | 10:00 p.m. |
| April 16, 2022 | Ontario Reign at San Diego Gulls | 10:00 p.m. |
| April 17, 2022 | Providence Bruins at Hershey Bears | 5:00 p.m. |
| April 19, 2022 | Utica Comets at Cleveland Monsters | 7:00 p.m. |
| April 19, 2022 | Grand Rapids Griffins at Iowa Wild | 8:00 p.m. |
| April 20, 2022 | Toronto Marlies at Belleville Senators | 7:00 p.m. |
| April 20, 2022 | Utica Comets at Cleveland Monsters | 7:00 p.m. |
| April 20, 2022 | Texas Stars at Milwaukee Admirals | 8:00 p.m. |
| April 20, 2022 | Grand Rapids Griffins at Rockford IceHogs | 8:00 p.m. |
| April 20, 2022 | Ontario Reign at Colorado Eagles | 9:05 p.m. |
| April 20, 2022 | San Jose Barracuda at Bakersfield Condors | 9:30 p.m. |
| April 20, 2022 | Tucson Roadrunners at Stockton Heat | 9:30 p.m. |
| April 20, 2022 | Abbotsford Canucks at San Diego Gulls | 10:00 p.m. |
| April 22, 2022 | Springfield Thunderbirds at Bridgeport Islanders | 7:00 p.m. |
| April 22, 2022 | Chicago Wolves at Grand Rapids Griffins | 7:00 p.m. |
| April 22, 2022 | Charlotte Checkers at Hartford Wolf Pack | 7:00 p.m. |
| April 22, 2022 | Toronto Marlies at Laval Rocket | 7:00 p.m. |
| April 22, 2022 | Belleville Senators at Syracuse Crunch | 7:00 p.m. |
| April 22, 2022 | Rochester Americans at Utica Comets | 7:00 p.m. |
| April 22, 2022 | Hershey Bears at Lehigh Valley Phantoms | 7:05 p.m. |
| April 22, 2022 | Wilkes-Barre/Scranton Penguins at Providence Bruins | 7:05 p.m. |
| April 22, 2022 | Texas Stars at Iowa Wild | 8:00 p.m. |
| April 22, 2022 | Ontario Reign at Colorado Eagles | 9:05 p.m. |
| April 22, 2022 | Tucson Roadrunners at Bakersfield Condors | 10:00 p.m. |
| April 22, 2022 | San Jose Barracuda at Henderson Silver Knights | 10:00 p.m. |
| April 22, 2022 | Abbotsford Canucks at Stockton Heat | 10:00 p.m. |
| April 23, 2022 | Wilkes-Barre/Scranton Penguins at Springfield Thunderbirds | 6:05 p.m. |
| April 23, 2022 | Hartford Wolf Pack at Bridgeport Islanders | 7:00 p.m. |
| April 23, 2022 | San Jose Barracuda at Henderson Silver Knights | 7:00 p.m. |
| April 23, 2022 | Lehigh Valley Phantoms at Hershey Bears | 7:00 p.m. |
| April 23, 2022 | Texas Stars at Iowa Wild | 7:00 p.m. |
| April 23, 2022 | Manitoba Moose at Rockford IceHogs | 7:00 p.m. |
| April 23, 2022 | Laval Rocket at Syracuse Crunch | 7:00 p.m. |
| April 23, 2022 | Charlotte Checkers at Providence Bruins | 7:05 p.m. |
| April 23, 2022 | Cleveland Monsters at Rochester Americans | 7:05 p.m. |
| April 23, 2022 | Milwaukee Admirals at Chicago Wolves | 8:00 p.m. |
| April 23, 2022 | Ontario Reign at Colorado Eagles | 9:05 p.m. |
| April 23, 2022 | Stockton Heat at Bakersfield Condors | 10:00 p.m. |
| April 23, 2022 | Tucson Roadrunners at San Diego Gulls | 10:00 p.m. |
| April 24, 2022 | Providence Bruins at Springfield Thunderbirds | 2:05 p.m. |
| April 24, 2022 | Rochester Americans at Cleveland Monsters | 3:00 p.m. |
| April 24, 2022 | Wilkes-Barre/Scranton Penguins at Hartford Wolf Pack | 3:00 p.m. |
| April 24, 2022 | Grand Rapids Griffins at Chicago Wolves | 4:00 p.m. |
| April 24, 2022 | Manitoba Moose at Milwaukee Admirals | 4:00 p.m. |
| April 24, 2022 | Belleville Senators at Toronto Marlies | 4:00 p.m. |
| April 24, 2022 | Syracuse Crunch at Hershey Bears | 5:00 p.m. |
| April 24, 2022 | Iowa Wild at Rockford IceHogs | 6:00 p.m. |
American Hockey League Schedule
