| | | |
| February 22, 2025 | Minnesota United FC 0 at Los Angeles FC 1 | Final |
| February 22, 2025 | Club de Foot Montreal 2 at Atlanta United FC 3 | Final |
| February 22, 2025 | Chicago Fire FC 2 at Columbus Crew SC 4 | Final |
| February 22, 2025 | Toronto FC 2 at D.C. United 2 | Final |
| February 22, 2025 | New York Red Bulls 0 at FC Cincinnati 1 | Final |
| February 22, 2025 | New York City FC 2 at Inter Miami CF 2 | Final |
| February 22, 2025 | Philadelphia Union 4 at Orlando City SC 2 | Final |
| February 22, 2025 | Sporting Kansas City 0 at Austin FC 1 | Final |
| February 22, 2025 | FC Dallas 2 at Houston Dynamo FC 1 | Final |
| February 22, 2025 | New England Revolution 0 at Nashville SC 0 | Final |
| February 22, 2025 | Colorado Rapids 0 at St. Louis City SC 0 | Final |
| February 22, 2025 | Real Salt Lake 0 at San Jose Earthquakes 4 | Final |
| February 22, 2025 | Charlotte FC 2 at Seattle Sounders FC 2 | Final |
| February 23, 2025 | Vancouver Whitecaps FC 4 at Portland Timbers 1 | Final |
| February 23, 2025 | San Diego FC 2 at LA Galaxy 0 | Final |
| March 1, 2025 | Atlanta United FC 0 at Charlotte FC 2 | Final |
| March 1, 2025 | Seattle Sounders FC 0 at Real Salt Lake 2 | Final |
| March 1, 2025 | Columbus Crew SC 1 at New England Revolution 0 | Final |
| March 1, 2025 | Nashville SC 0 at New York Red Bulls 2 | Final |
| March 1, 2025 | Toronto FC 2 at Orlando City SC 4 | Final |
| March 1, 2025 | FC Cincinnati 1 at Philadelphia Union 4 | Final |
| March 1, 2025 | D.C. United 2 at Chicago Fire FC 2 | Final |
| March 1, 2025 | Club de Foot Montreal 0 at Minnesota United FC 1 | Final |
| March 1, 2025 | San Jose Earthquakes 2 at Sporting Kansas City 1 | Final |
| March 1, 2025 | FC Dallas 3 at Colorado Rapids 3 | Final |
| March 1, 2025 | New York City FC 0 at Los Angeles FC 1 | Final |
| March 1, 2025 | Austin FC 0 at Portland Timbers 1 | Final |
| March 1, 2025 | St. Louis City SC 0 at San Diego FC 0 | Final |
| March 2, 2025 | LA Galaxy 1 at Vancouver Whitecaps FC 2 | Final |
| March 2, 2025 | Inter Miami CF 4 at Houston Dynamo FC 1 | Final |
| March 8, 2025 | Houston Dynamo FC 0 at Columbus Crew SC 0 | Final |
| March 8, 2025 | Los Angeles FC 2 at Seattle Sounders FC 5 | Final |
| March 8, 2025 | New York Red Bulls 0 at Atlanta United FC 0 | Final |
| March 8, 2025 | Sporting Kansas City 1 at D.C. United 2 | Final |
| March 8, 2025 | Toronto FC 0 at FC Cincinnati 2 | Final |
| March 8, 2025 | Philadelphia Union 2 at New England Revolution 0 | Final |
| March 8, 2025 | Orlando City SC 1 at New York City FC 2 | Final |
| March 8, 2025 | Colorado Rapids 1 at Austin FC 0 | Final |
| March 8, 2025 | Chicago Fire FC 3 at FC Dallas 1 | Final |
| March 8, 2025 | Portland Timbers 0 at Nashville SC 2 | Final |
| March 8, 2025 | San Diego FC 3 at Real Salt Lake 1 | Final |
| March 8, 2025 | Club de Foot Montreal 0 at Vancouver Whitecaps FC 2 | Final |
| March 8, 2025 | Minnesota United FC 1 at San Jose Earthquakes 0 | Final |
| March 9, 2025 | Charlotte FC 0 at Inter Miami CF 1 | Final |
| March 9, 2025 | St. Louis City SC 3 at LA Galaxy 0 | Final |
| March 15, 2025 | Orlando City SC 2 at New York Red Bulls 2 | Final |
| March 15, 2025 | Chicago Fire FC 2 at Toronto FC 1 | Final |
| March 15, 2025 | Austin FC 1 at Los Angeles FC 0 | Final |
| March 15, 2025 | FC Cincinnati 0 at Charlotte FC 2 | Final |
| March 15, 2025 | Club de Foot Montreal 0 at D.C. United 0 | Final |
| March 15, 2025 | New England Revolution 1 at New York City FC 2 | Final |
| March 15, 2025 | Minnesota United FC 3 at Sporting Kansas City 3 | Final |
| March 15, 2025 | Vancouver Whitecaps FC 1 at FC Dallas 0 | Final |
| March 15, 2025 | Real Salt Lake 2 at Houston Dynamo FC 1 | Final |
| March 15, 2025 | Seattle Sounders FC 0 at St. Louis City SC 1 | Final |
| March 15, 2025 | Columbus Crew SC 1 at San Diego FC 1 | Final |
| March 15, 2025 | Colorado Rapids 2 at San Jose Earthquakes 1 | Final |
| March 16, 2025 | Nashville SC 3 at Philadelphia Union 1 | Final |
| March 16, 2025 | LA Galaxy 1 at Portland Timbers 1 | Final |
| March 16, 2025 | Inter Miami CF 2 at Atlanta United FC 1 | Final |
| March 22, 2025 | Atlanta United FC 2 at FC Cincinnati 2 | Final |
| March 22, 2025 | LA Galaxy 2 at Minnesota United FC 2 | Final |
| March 22, 2025 | San Jose Earthquakes 1 at Charlotte FC 4 | Final |
| March 22, 2025 | New York City FC 0 at Columbus Crew SC 0 | Final |
| March 22, 2025 | Toronto FC 1 at New York Red Bulls 2 | Final |
| March 22, 2025 | D.C. United 1 at Orlando City SC 4 | Final |
| March 22, 2025 | St. Louis City SC 0 at Philadelphia Union 1 | Final |
| March 22, 2025 | Club de Foot Montreal 0 at Nashville SC 3 | Final |
| March 22, 2025 | Los Angeles FC 2 at Sporting Kansas City 0 | Final |
| March 22, 2025 | Portland Timbers 3 at Colorado Rapids 0 | Final |
| March 22, 2025 | FC Dallas 1 at Real Salt Lake 0 | Final |
| March 22, 2025 | Houston Dynamo FC 0 at Seattle Sounders FC 0 | Final |
| March 22, 2025 | Chicago Fire FC 3 at Vancouver Whitecaps FC 1 | Final |
| March 23, 2025 | San Diego FC 1 at Austin FC 2 | Final |
| March 29, 2025 | New York Red Bulls 1 at New England Revolution 2 | Final |
| March 29, 2025 | Vancouver Whitecaps FC 0 at Toronto FC 0 | Final |
| March 29, 2025 | Charlotte FC 0 at Colorado Rapids 2 | Final |
| March 29, 2025 | New York City FC 3 at Atlanta United FC 4 | Final |
| March 29, 2025 | Columbus Crew SC 2 at D.C. United 1 | Final |
| March 29, 2025 | Philadelphia Union 1 at Inter Miami CF 2 | Final |
| March 29, 2025 | Club de Foot Montreal 1 at Chicago Fire FC 1 | Final |
| March 29, 2025 | Sporting Kansas City 1 at FC Dallas 2 | Final |
| March 29, 2025 | Real Salt Lake 0 at Minnesota United FC 2 | Final |
| March 29, 2025 | FC Cincinnati 2 at Nashville SC 1 | Final |
| March 29, 2025 | Orlando City SC 2 at LA Galaxy 1 | Final |
| March 29, 2025 | Los Angeles FC 2 at San Diego FC 3 | Final |
| March 29, 2025 | Seattle Sounders FC 1 at San Jose Earthquakes 1 | Final |
| March 30, 2025 | Austin FC 1 at St. Louis City SC 0 | Final |
| March 30, 2025 | Houston Dynamo FC 1 at Portland Timbers 3 | Final |
| April 5, 2025 | Nashville SC 1 at Charlotte FC 2 | Final |
| April 5, 2025 | LA Galaxy 0 at Real Salt Lake 2 | Final |
| April 5, 2025 | FC Dallas 1 at Atlanta United FC 1 | Final |
| April 5, 2025 | Portland Timbers 0 at Austin FC 0 | Final |
| April 5, 2025 | Club de Foot Montreal 1 at Columbus Crew SC 2 | Final |
| April 5, 2025 | New England Revolution 0 at FC Cincinnati 1 | Final |
| April 5, 2025 | Chicago Fire FC 1 at New York Red Bulls 2 | Final |
| April 5, 2025 | Orlando City SC 0 at Philadelphia Union 0 | Final |
| April 5, 2025 | Los Angeles FC 0 at Houston Dynamo FC 1 | Final |
| April 5, 2025 | St. Louis City SC 0 at Sporting Kansas City 2 | Final |
| April 5, 2025 | Colorado Rapids 0 at Vancouver Whitecaps FC 2 | Final |
| April 5, 2025 | Seattle Sounders FC 0 at San Diego FC 3 | Final |
| April 6, 2025 | Minnesota United FC 2 at New York City FC 1 | Final |
| April 6, 2025 | D.C. United 1 at San Jose Earthquakes 6 | Final |
| April 6, 2025 | Toronto FC 1 at Inter Miami CF 1 | Final |
| April 12, 2025 | New England Revolution 1 at Atlanta United FC 0 | Final |
| April 12, 2025 | Minnesota United FC 0 at Toronto FC 0 | Final |
| April 12, 2025 | New York Red Bulls 0 at Orlando City SC 0 | Final |
| April 12, 2025 | Charlotte FC 1 at Club de Foot Montreal 0 | Final |
| April 12, 2025 | FC Cincinnati 1 at D.C. United 0 | Final |
| April 12, 2025 | Philadelphia Union 0 at New York City FC 1 | Final |
| April 12, 2025 | Austin FC 1 at Vancouver Whitecaps FC 5 | Final |
| April 12, 2025 | Seattle Sounders FC 1 at FC Dallas 0 | Final |
| April 12, 2025 | Real Salt Lake 1 at Nashville SC 2 | Final |
| April 12, 2025 | San Diego FC 2 at Colorado Rapids 3 | Final |
| April 12, 2025 | Houston Dynamo FC 1 at LA Galaxy 1 | Final |
| April 12, 2025 | San Jose Earthquakes 1 at Los Angeles FC 2 | Final |
| April 13, 2025 | Portland Timbers 4 at Sporting Kansas City 2 | Final |
| April 13, 2025 | Inter Miami CF 0 at Chicago Fire FC 0 | Final |
| April 13, 2025 | Columbus Crew SC 2 at St. Louis City SC 1 | Final |
| April 19, 2025 | LA Galaxy 0 at Austin FC 1 | Final |
| April 19, 2025 | Inter Miami CF 1 at Columbus Crew SC 0 | Final |
| April 19, 2025 | San Diego FC 0 at Charlotte FC 3 | Final |
| April 19, 2025 | Orlando City SC 0 at Club de Foot Montreal 0 | Final |
| April 19, 2025 | New York City FC 0 at New England Revolution 2 | Final |
| April 19, 2025 | D.C. United 2 at New York Red Bulls 1 | Final |
| April 19, 2025 | Atlanta United FC 0 at Philadelphia Union 3 | Final |
| April 19, 2025 | Nashville SC 0 at Seattle Sounders FC 3 | Final |
| April 19, 2025 | FC Cincinnati 3 at Chicago Fire FC 2 | Final |
| April 19, 2025 | Colorado Rapids 2 at Houston Dynamo FC 2 | Final |
| April 19, 2025 | FC Dallas 0 at Minnesota United FC 0 | Final |
| April 19, 2025 | Vancouver Whitecaps FC 0 at St. Louis City SC 0 | Final |
| April 19, 2025 | Toronto FC 1 at Real Salt Lake 0 | Final |
| April 19, 2025 | Los Angeles FC 3 at Portland Timbers 3 | Final |
| April 19, 2025 | Sporting Kansas City 5 at San Jose Earthquakes 3 | Final |
| April 26, 2025 | Sporting Kansas City 1 at FC Cincinnati 2 | Final |
| April 26, 2025 | New York City FC 1 at Toronto FC 0 | Final |
| April 26, 2025 | Club de Foot Montreal 0 at New York Red Bulls 1 | Final |
| April 26, 2025 | D.C. United 0 at Philadelphia Union 3 | Final |
| April 26, 2025 | Atlanta United FC 0 at Orlando City SC 3 | Final |
| April 26, 2025 | New England Revolution 1 at Charlotte FC 0 | Final |
| April 26, 2025 | San Jose Earthquakes 1 at Columbus Crew SC 2 | Final |
| April 26, 2025 | Real Salt Lake 3 at San Diego FC 1 | Final |
| April 26, 2025 | Austin FC 0 at Houston Dynamo FC 2 | Final |
| April 26, 2025 | Chicago Fire FC 2 at Nashville SC 7 | Final |
| April 26, 2025 | Seattle Sounders FC 1 at Colorado Rapids 1 | Final |
| April 27, 2025 | Vancouver Whitecaps FC 3 at Minnesota United FC 1 | Final |
| April 27, 2025 | FC Dallas 4 at Inter Miami CF 3 | Final |
| April 27, 2025 | St. Louis City SC 2 at Los Angeles FC 2 | Final |
| April 27, 2025 | Portland Timbers 4 at LA Galaxy 2 | Final |
| May 3, 2025 | Nashville SC 1 at Atlanta United FC 1 | Final |
| May 3, 2025 | New England Revolution 2 at Toronto FC 0 | Final |
| May 3, 2025 | Philadelphia Union 2 at Club de Foot Montreal 1 | Final |
| May 3, 2025 | Charlotte FC 2 at Columbus Crew SC 4 | Final |
| May 3, 2025 | Colorado Rapids 1 at D.C. United 2 | Final |
| May 3, 2025 | New York Red Bulls 1 at Inter Miami CF 4 | Final |
| May 3, 2025 | Minnesota United FC 3 at Austin FC 0 | Final |
| May 3, 2025 | Orlando City SC 0 at Chicago Fire FC 0 | Final |
| May 3, 2025 | FC Dallas 0 at San Diego FC 5 | Final |
| May 3, 2025 | Real Salt Lake 1 at Vancouver Whitecaps FC 2 | Final |
| May 3, 2025 | Houston Dynamo FC 0 at Los Angeles FC 2 | Final |
| May 3, 2025 | Portland Timbers 1 at San Jose Earthquakes 4 | Final |
| May 3, 2025 | St. Louis City SC 1 at Seattle Sounders FC 4 | Final |
| May 4, 2025 | FC Cincinnati 0 at New York City FC 1 | Final |
| May 4, 2025 | LA Galaxy 0 at Sporting Kansas City 1 | Final |
| May 10, 2025 | Atlanta United FC 1 at Chicago Fire FC 2 | Final |
| May 10, 2025 | Inter Miami CF 1 at Minnesota United FC 4 | Final |
| May 10, 2025 | D.C. United 0 at Toronto FC 2 | Final |
| May 10, 2025 | Austin FC 1 at FC Cincinnati 2 | Final |
| May 10, 2025 | Club de Foot Montreal 1 at New York City FC 0 | Final |
| May 10, 2025 | LA Galaxy 0 at New York Red Bulls 7 | Final |
| May 10, 2025 | New England Revolution 3 at Orlando City SC 3 | Final |
| May 10, 2025 | Columbus Crew SC 2 at Philadelphia Union 2 | Final |
| May 10, 2025 | Real Salt Lake 1 at FC Dallas 1 | Final |
| May 10, 2025 | Seattle Sounders FC 3 at Houston Dynamo FC 1 | Final |
| May 10, 2025 | Charlotte FC 1 at Nashville SC 2 | Final |
| May 10, 2025 | San Diego FC 2 at St. Louis City SC 1 | Final |
| May 10, 2025 | San Jose Earthquakes 2 at Colorado Rapids 0 | Final |
| May 10, 2025 | Sporting Kansas City 0 at Portland Timbers 1 | Final |
| May 11, 2025 | Los Angeles FC 2 at Vancouver Whitecaps FC 2 | Final |
| May 14, 2025 | Columbus Crew SC 1 at Club de Foot Montreal 1 | Final |
| May 14, 2025 | New York City FC 0 at D.C. United 0 | Final |
| May 14, 2025 | Charlotte FC 1 at Orlando City SC 3 | Final |
| May 14, 2025 | LA Galaxy 2 at Philadelphia Union 3 | Final |
| May 14, 2025 | FC Cincinnati 1 at Toronto FC 0 | Final |
| May 14, 2025 | Minnesota United FC 0 at Houston Dynamo FC 2 | Final |
| May 14, 2025 | New York Red Bulls 1 at Nashville SC 2 | Final |
| May 14, 2025 | Sporting Kansas City 2 at St. Louis City SC 2 | Final |
| May 14, 2025 | Atlanta United FC 1 at Austin FC 1 | Final |
| May 14, 2025 | Portland Timbers 0 at Real Salt Lake 0 | Final |
| May 14, 2025 | Seattle Sounders FC 0 at Los Angeles FC 4 | Final |
| May 14, 2025 | Colorado Rapids 0 at San Diego FC 2 | Final |
| May 14, 2025 | Inter Miami CF 3 at San Jose Earthquakes 3 | Final |
| May 17, 2025 | Toronto FC 6 at Club de Foot Montreal 1 | Final |
| May 17, 2025 | New York Red Bulls 0 at New York City FC 2 | Final |
| May 17, 2025 | FC Cincinnati 1 at Columbus Crew SC 1 | Final |
| May 17, 2025 | Philadelphia Union 1 at Atlanta United FC 0 | Final |
| May 17, 2025 | Chicago Fire FC 4 at Charlotte FC 1 | Final |
| May 17, 2025 | San Jose Earthquakes 0 at New England Revolution 0 | Final |
| May 17, 2025 | Vancouver Whitecaps FC 0 at Austin FC 0 | Final |
| May 17, 2025 | Houston Dynamo FC 2 at FC Dallas 0 | Final |
| May 17, 2025 | St. Louis City SC 0 at Minnesota United FC 3 | Final |
| May 17, 2025 | D.C. United 0 at Nashville SC 0 | Final |
| May 17, 2025 | Real Salt Lake 0 at Colorado Rapids 1 | Final |
| May 17, 2025 | Seattle Sounders FC 1 at Portland Timbers 1 | Final |
| May 17, 2025 | Sporting Kansas City 0 at San Diego FC 0 | Final |
| May 18, 2025 | Orlando City SC 3 at Inter Miami CF 0 | Final |
| May 18, 2025 | Los Angeles FC 2 at LA Galaxy 2 | Final |
| May 24, 2025 | FC Dallas 0 at Seattle Sounders FC 1 | Final |
| May 24, 2025 | LA Galaxy 1 at San Diego FC 2 | Final |
| May 24, 2025 | Columbus Crew SC 2 at Charlotte FC 3 | Final |
| May 24, 2025 | Los Angeles FC 2 at Club de Foot Montreal 2 | Final |
| May 24, 2025 | New York Red Bulls 2 at D.C. United 0 | Final |
| May 24, 2025 | Portland Timbers 0 at Orlando City SC 1 | Final |
| May 24, 2025 | Inter Miami CF 3 at Philadelphia Union 3 | Final |
| May 24, 2025 | Nashville SC 2 at Toronto FC 1 | Final |
| May 24, 2025 | Austin FC 1 at Minnesota United FC 1 | Final |
| May 24, 2025 | New England Revolution 3 at Sporting Kansas City 3 | Final |
| May 24, 2025 | St. Louis City SC 0 at Colorado Rapids 1 | Final |
| May 24, 2025 | Vancouver Whitecaps FC 3 at Real Salt Lake 2 | Final |
| May 24, 2025 | Houston Dynamo FC 3 at San Jose Earthquakes 3 | Final |
| May 25, 2025 | Chicago Fire FC 1 at New York City FC 3 | Final |
| May 25, 2025 | FC Cincinnati 2 at Atlanta United FC 4 | Final |
| May 28, 2025 | Orlando City SC 2 at Atlanta United FC 3 | Final |
| May 28, 2025 | New England Revolution 1 at D.C. United 1 | Final |
| May 28, 2025 | FC Dallas 3 at FC Cincinnati 3 | Final |
| May 28, 2025 | Club de Foot Montreal 2 at Inter Miami CF 4 | Final |
| May 28, 2025 | Houston Dynamo FC 3 at New York City FC 0 | Final |
| May 28, 2025 | Charlotte FC 2 at New York Red Bulls 4 | Final |
| May 28, 2025 | Philadelphia Union 2 at Toronto FC 1 | Final |
| May 28, 2025 | Nashville SC 2 at Columbus Crew SC 2 | Final |
| May 28, 2025 | Real Salt Lake 1 at Austin FC 1 | Final |
| May 28, 2025 | San Diego FC 0 at Seattle Sounders FC 1 | Final |
| May 28, 2025 | San Jose Earthquakes 1 at LA Galaxy 0 | Final |
| May 28, 2025 | Colorado Rapids 1 at Portland Timbers 2 | Final |
| May 28, 2025 | Minnesota United FC 0 at Vancouver Whitecaps FC 0 | Final |
| May 31, 2025 | San Jose Earthquakes 1 at St. Louis City SC 2 | Final |
| May 31, 2025 | New York City FC 2 at Nashville SC 2 | Final |
| May 31, 2025 | New England Revolution 3 at Club de Foot Montreal 0 | Final |
| May 31, 2025 | D.C. United 2 at FC Cincinnati 1 | Final |
| May 31, 2025 | Columbus Crew SC 1 at Inter Miami CF 5 | Final |
| May 31, 2025 | Atlanta United FC 0 at New York Red Bulls 2 | Final |
| May 31, 2025 | Chicago Fire FC 3 at Orlando City SC 1 | Final |
| May 31, 2025 | Charlotte FC 2 at Toronto FC 0 | Final |
| May 31, 2025 | Philadelphia Union 0 at FC Dallas 0 | Final |
| May 31, 2025 | Sporting Kansas City 3 at Houston Dynamo FC 1 | Final |
| May 31, 2025 | Real Salt Lake 0 at LA Galaxy 2 | Final |
| May 31, 2025 | Austin FC 0 at San Diego FC 2 | Final |
| June 1, 2025 | Minnesota United FC 3 at Seattle Sounders FC 2 | Final |
| June 7, 2025 | Chicago Fire FC 7 at D.C. United 1 | Final |
| June 7, 2025 | Austin FC 2 at Colorado Rapids 0 | Final |
| June 8, 2025 | St. Louis City SC 1 at Portland Timbers 2 | Final |
| June 8, 2025 | Sporting Kansas City 1 at Los Angeles FC 3 | Final |
| June 8, 2025 | Seattle Sounders FC 0 at Vancouver Whitecaps FC 3 | Final |
| June 12, 2025 | Atlanta United FC 0 at New York City FC 4 | Final |
| June 13, 2025 | San Jose Earthquakes 1 at Portland Timbers 1 | Final |
| June 14, 2025 | LA Galaxy 3 at St. Louis City SC 3 | Final |
| June 14, 2025 | Vancouver Whitecaps FC 1 at Columbus Crew SC 2 | Final |
| June 14, 2025 | FC Cincinnati 1 at New England Revolution 0 | Final |
| June 14, 2025 | Charlotte FC 1 at Philadelphia Union 2 | Final |
| June 14, 2025 | New York Red Bulls 1 at Austin FC 2 | Final |
| June 14, 2025 | Nashville SC 2 at Chicago Fire FC 0 | Final |
| June 14, 2025 | Club de Foot Montreal 3 at Houston Dynamo FC 1 | Final |
| June 14, 2025 | San Diego FC 4 at Minnesota United FC 2 | Final |
| June 14, 2025 | FC Dallas 4 at Sporting Kansas City 2 | Final |
| June 14, 2025 | Orlando City SC 1 at Colorado Rapids 0 | Final |
| June 14, 2025 | D.C. United 0 at Real Salt Lake 2 | Final |
| June 25, 2025 | FC Cincinnati 3 at Club de Foot Montreal 1 | Final |
| June 25, 2025 | Atlanta United FC 1 at Columbus Crew SC 3 | Final |
| June 25, 2025 | Nashville SC 3 at New England Revolution 2 | Final |
| June 25, 2025 | New York Red Bulls 1 at Toronto FC 1 | Final |
| June 25, 2025 | Philadelphia Union 1 at Chicago Fire FC 0 | Final |
| June 25, 2025 | San Jose Earthquakes 4 at FC Dallas 2 | Final |
| June 25, 2025 | Houston Dynamo FC 1 at Minnesota United FC 3 | Final |
| June 25, 2025 | Charlotte FC 1 at Sporting Kansas City 2 | Final |
| June 25, 2025 | Orlando City SC 4 at St. Louis City SC 2 | Final |
| June 25, 2025 | LA Galaxy 0 at Colorado Rapids 2 | Final |
| June 25, 2025 | San Diego FC 5 at Vancouver Whitecaps FC 3 | Final |
| June 28, 2025 | New York City FC 0 at Club de Foot Montreal 1 | Final |
| June 28, 2025 | Nashville SC 1 at D.C. United 0 | Final |
| June 28, 2025 | Colorado Rapids 3 at New England Revolution 3 | Final |
| June 28, 2025 | Minnesota United FC 2 at New York Red Bulls 2 | Final |
| June 28, 2025 | FC Cincinnati 2 at Orlando City SC 1 | Final |
| June 28, 2025 | Portland Timbers 0 at Toronto FC 3 | Final |
| June 28, 2025 | Charlotte FC 2 at Chicago Fire FC 3 | Final |
| June 28, 2025 | San Diego FC 3 at FC Dallas 2 | Final |
| June 28, 2025 | St. Louis City SC 0 at Houston Dynamo FC 1 | Final |
| June 28, 2025 | Real Salt Lake 1 at Sporting Kansas City 1 | Final |
| June 28, 2025 | LA Galaxy 1 at San Jose Earthquakes 1 | Final |
| June 28, 2025 | Austin FC 0 at Seattle Sounders FC 2 | Final |
| June 29, 2025 | Philadelphia Union 0 at Columbus Crew SC 1 | Final |
| June 29, 2025 | Vancouver Whitecaps FC 1 at Los Angeles FC 0 | Final |
| July 3, 2025 | Toronto FC 1 at New York City FC 3 | Final |
| July 4, 2025 | Minnesota United FC 2 at FC Dallas 1 | Final |
| July 4, 2025 | Sporting Kansas City 2 at Colorado Rapids 1 | Final |
| July 4, 2025 | Vancouver Whitecaps FC 0 at LA Galaxy 3 | Final |
| July 5, 2025 | Orlando City SC 2 at Charlotte FC 2 | Final |
| July 5, 2025 | Inter Miami CF 4 at Club de Foot Montreal 1 | Final |
| July 5, 2025 | Atlanta United FC 0 at D.C. United 0 | Final |
| July 5, 2025 | Chicago Fire FC 1 at FC Cincinnati 2 | Final |
| July 5, 2025 | Philadelphia Union 0 at Nashville SC 1 | Final |
| July 5, 2025 | Los Angeles FC at Austin FC | Ppd. |
| July 5, 2025 | St. Louis City SC 2 at Real Salt Lake 3 | Final |
| July 5, 2025 | New England Revolution 1 at Portland Timbers 2 | Final |
| July 5, 2025 | Houston Dynamo FC 4 at San Diego FC 3 | Final |
| July 5, 2025 | New York Red Bulls 1 at San Jose Earthquakes 1 | Final |
| July 6, 2025 | Columbus Crew SC 1 at Seattle Sounders FC 1 | Final |
| July 9, 2025 | Inter Miami CF 2 at New England Revolution 1 | Final |
| July 9, 2025 | Colorado Rapids 0 at Los Angeles FC 3 | Final |
| July 12, 2025 | New York City FC 0 at Charlotte FC 2 | Final |
| July 12, 2025 | Columbus Crew SC 4 at FC Cincinnati 2 | Final |
| July 12, 2025 | Nashville SC 1 at Inter Miami CF 2 | Final |
| July 12, 2025 | Club de Foot Montreal 1 at Orlando City SC 1 | Final |
| July 12, 2025 | New York Red Bulls 0 at Philadelphia Union 2 | Final |
| July 12, 2025 | Atlanta United FC 1 at Toronto FC 1 | Final |
| July 12, 2025 | New England Revolution 0 at Austin FC 0 | Final |
| July 12, 2025 | San Diego FC 2 at Chicago Fire FC 1 | Final |
| July 12, 2025 | San Jose Earthquakes 1 at Minnesota United FC 4 | Final |
| July 12, 2025 | Seattle Sounders FC 3 at Sporting Kansas City 2 | Final |
| July 12, 2025 | Vancouver Whitecaps FC 0 at Colorado Rapids 3 | Final |
| July 12, 2025 | Houston Dynamo FC 0 at Real Salt Lake 1 | Final |
| July 12, 2025 | D.C. United 1 at LA Galaxy 2 | Final |
| July 12, 2025 | FC Dallas 0 at Los Angeles FC 2 | Final |
| July 13, 2025 | Portland Timbers 1 at St. Louis City SC 2 | Final |
| July 16, 2025 | Chicago Fire FC 2 at Atlanta United FC 2 | Final |
| July 16, 2025 | D.C. United 1 at Charlotte FC 2 | Final |
| July 16, 2025 | Inter Miami CF 0 at FC Cincinnati 3 | Final |
| July 16, 2025 | New England Revolution 3 at New York Red Bulls 5 | Final |
| July 16, 2025 | New York City FC 2 at Orlando City SC 1 | Final |
| July 16, 2025 | Club de Foot Montreal 1 at Philadelphia Union 2 | Final |
| July 16, 2025 | Vancouver Whitecaps FC 3 at Houston Dynamo FC 0 | Final |
| July 16, 2025 | Los Angeles FC 1 at Minnesota United FC 0 | Final |
| July 16, 2025 | Columbus Crew SC 0 at Nashville SC 3 | Final |
| July 16, 2025 | Colorado Rapids 3 at Seattle Sounders FC 3 | Final |
| July 16, 2025 | Austin FC 2 at LA Galaxy 1 | Final |
| July 16, 2025 | Real Salt Lake 1 at Portland Timbers 0 | Final |
| July 16, 2025 | Toronto FC 1 at San Diego FC 0 | Final |
| July 16, 2025 | FC Dallas 2 at San Jose Earthquakes 2 | Final |
| July 19, 2025 | Charlotte FC 3 at Atlanta United FC 2 | Final |
| July 19, 2025 | Chicago Fire FC 2 at Club de Foot Montreal 0 | Final |
| July 19, 2025 | D.C. United 1 at Columbus Crew SC 2 | Final |
| July 19, 2025 | Orlando City SC 2 at New England Revolution 1 | Final |
| July 19, 2025 | Inter Miami CF 5 at New York Red Bulls 1 | Final |
| July 19, 2025 | St. Louis City SC 0 at FC Dallas 3 | Final |
| July 19, 2025 | Philadelphia Union 1 at Houston Dynamo FC 1 | Final |
| July 19, 2025 | Toronto FC 0 at Nashville SC 1 | Final |
| July 19, 2025 | San Jose Earthquakes 2 at Seattle Sounders FC 3 | Final |
| July 19, 2025 | New York City FC 1 at Sporting Kansas City 1 | Final |
| July 19, 2025 | FC Cincinnati 1 at Real Salt Lake 0 | Final |
| July 19, 2025 | LA Galaxy 3 at Los Angeles FC 3 | Final |
| July 19, 2025 | Minnesota United FC 1 at Portland Timbers 1 | Final |
| July 19, 2025 | Vancouver Whitecaps FC 1 at San Diego FC 1 | Final |
| July 25, 2025 | Orlando City SC 3 at Columbus Crew SC 1 | Final |
| July 25, 2025 | Club de Foot Montreal 3 at New England Revolution 1 | Final |
| July 25, 2025 | New York City FC 4 at FC Dallas 3 | Final |
| July 25, 2025 | LA Galaxy at Houston Dynamo FC | Ppd. |
| July 25, 2025 | Portland Timbers 1 at Los Angeles FC 0 | Final |
| July 25, 2025 | Nashville SC 0 at San Diego FC 1 | Final |
| July 26, 2025 | FC Cincinnati 0 at Inter Miami CF 0 | Final |
| July 26, 2025 | Seattle Sounders FC 2 at Atlanta United FC 2 | Final |
| July 26, 2025 | Toronto FC 0 at Charlotte FC 2 | Final |
| July 26, 2025 | Austin FC 4 at D.C. United 2 | Final |
| July 26, 2025 | Colorado Rapids 1 at Philadelphia Union 3 | Final |
| July 26, 2025 | New York Red Bulls 0 at Chicago Fire FC 1 | Final |
| July 26, 2025 | Minnesota United FC 2 at St. Louis City SC 1 | Final |
| July 26, 2025 | San Jose Earthquakes 1 at Real Salt Lake 2 | Final |
| July 26, 2025 | Sporting Kansas City 0 at Vancouver Whitecaps FC 3 | Final |
| August 9, 2025 | Atlanta United FC 1 at Club de Foot Montreal 1 | Final |
| August 9, 2025 | D.C. United 0 at New England Revolution 2 | Final |
| August 9, 2025 | Toronto FC 1 at Philadelphia Union 1 | Final |
| August 9, 2025 | Houston Dynamo FC 2 at Austin FC 2 | Final |
| August 9, 2025 | Los Angeles FC 2 at Chicago Fire FC 2 | Final |
| August 9, 2025 | Portland Timbers 0 at FC Dallas 2 | Final |
| August 9, 2025 | San Diego FC 2 at Sporting Kansas City 0 | Final |
| August 9, 2025 | Nashville SC 1 at St. Louis City SC 3 | Final |
| August 9, 2025 | Vancouver Whitecaps FC 1 at San Jose Earthquakes 2 | Final |
| August 10, 2025 | Charlotte FC 1 at FC Cincinnati 0 | Final |
| August 10, 2025 | Colorado Rapids 2 at Minnesota United FC 1 | Final |
| August 10, 2025 | Real Salt Lake 1 at New York Red Bulls 2 | Final |
| August 10, 2025 | Inter Miami CF 1 at Orlando City SC 4 | Final |
| August 10, 2025 | Seattle Sounders FC 4 at LA Galaxy 0 | Final |
| August 16, 2025 | Real Salt Lake 0 at Charlotte FC 1 | Final |
| August 16, 2025 | D.C. United 1 at Club de Foot Montreal 1 | Final |
| August 16, 2025 | LA Galaxy 1 at Inter Miami CF 3 | Final |
| August 16, 2025 | Los Angeles FC 2 at New England Revolution 0 | Final |
| August 16, 2025 | Philadelphia Union 0 at New York Red Bulls 1 | Final |
| August 16, 2025 | Sporting Kansas City 1 at Orlando City SC 3 | Final |
| August 16, 2025 | Columbus Crew SC 1 at Toronto FC 1 | Final |
| August 16, 2025 | FC Dallas 1 at Austin FC 1 | Final |
| August 16, 2025 | St. Louis City SC 2 at Chicago Fire FC 3 | Final |
| August 16, 2025 | Seattle Sounders FC 0 at Minnesota United FC 1 | Final |
| August 16, 2025 | Atlanta United FC 1 at Colorado Rapids 3 | Final |
| August 16, 2025 | FC Cincinnati 3 at Portland Timbers 2 | Final |
| August 17, 2025 | Nashville SC 1 at New York City FC 2 | Final |
| August 17, 2025 | San Diego FC 2 at San Jose Earthquakes 1 | Final |
| August 17, 2025 | Houston Dynamo FC 1 at Vancouver Whitecaps FC 1 | Final |
| August 23, 2025 | Austin FC 2 at Club de Foot Montreal 3 | Final |
| August 23, 2025 | New England Revolution 2 at Columbus Crew SC 1 | Final |
| August 23, 2025 | Inter Miami CF 1 at D.C. United 1 | Final |
| August 23, 2025 | New York City FC 1 at FC Cincinnati 0 | Final |
| August 23, 2025 | Chicago Fire FC 0 at Philadelphia Union 4 | Final |
| August 23, 2025 | Los Angeles FC 1 at FC Dallas 1 | Final |
| August 23, 2025 | San Jose Earthquakes 2 at Houston Dynamo FC 1 | Final |
| August 23, 2025 | Orlando City SC 1 at Nashville SC 5 | Final |
| August 23, 2025 | Minnesota United FC 3 at Real Salt Lake 1 | Final |
| August 23, 2025 | St. Louis City SC 2 at Vancouver Whitecaps FC 3 | Final |
| August 23, 2025 | Colorado Rapids 0 at LA Galaxy 3 | Final |
| August 23, 2025 | Portland Timbers 0 at San Diego FC 0 | Final |
| August 24, 2025 | Toronto FC 0 at Atlanta United FC 0 | Final |
| August 24, 2025 | New York Red Bulls 0 at Charlotte FC 1 | Final |
| August 24, 2025 | Sporting Kansas City 2 at Seattle Sounders FC 5 | Final |
| August 30, 2025 | Philadelphia Union 1 at FC Cincinnati 0 | Final |
| August 30, 2025 | Charlotte FC 2 at New England Revolution 1 | Final |
| August 30, 2025 | D.C. United 2 at New York City FC 1 | Final |
| August 30, 2025 | Columbus Crew SC 0 at New York Red Bulls 0 | Final |
| August 30, 2025 | Club de Foot Montreal 1 at Toronto FC 1 | Final |
| August 30, 2025 | San Jose Earthquakes 1 at Austin FC 3 | Final |
| August 30, 2025 | Portland Timbers 1 at Minnesota United FC 1 | Final |
| August 30, 2025 | Atlanta United FC 1 at Nashville SC 0 | Final |
| August 30, 2025 | Colorado Rapids 2 at Sporting Kansas City 4 | Final |
| August 30, 2025 | Houston Dynamo FC 3 at St. Louis City SC 2 | Final |
| August 31, 2025 | San Diego FC 2 at Los Angeles FC 1 | Final |
| September 6, 2025 | New England Revolution 2 at Chicago Fire FC 3 | Final |
| September 6, 2025 | LA Galaxy 1 at Houston Dynamo FC 1 | Final |
| September 6, 2025 | FC Dallas 1 at St. Louis City SC 1 | Final |
| September 7, 2025 | Austin FC 2 at Sporting Kansas City 1 | Final |
| September 13, 2025 | Columbus Crew SC 5 at Atlanta United FC 4 | Final |
| September 13, 2025 | Inter Miami CF 0 at Charlotte FC 3 | Final |
| September 13, 2025 | St. Louis City SC 2 at Club de Foot Montreal 0 | Final |
| September 13, 2025 | Orlando City SC 1 at D.C. United 1 | Final |
| September 13, 2025 | Nashville SC 1 at FC Cincinnati 2 | Final |
| September 13, 2025 | Toronto FC 1 at New England Revolution 1 | Final |
| September 13, 2025 | New York City FC 3 at Chicago Fire FC 1 | Final |
| September 13, 2025 | Austin FC 0 at FC Dallas 2 | Final |
| September 13, 2025 | Los Angeles FC 4 at San Jose Earthquakes 2 | Final |
| September 13, 2025 | LA Galaxy 2 at Seattle Sounders FC 2 | Final |
| September 13, 2025 | Houston Dynamo FC 1 at Colorado Rapids 2 | Final |
| September 13, 2025 | Sporting Kansas City 1 at Real Salt Lake 2 | Final |
| September 13, 2025 | Philadelphia Union 0 at Vancouver Whitecaps FC 7 | Final |
| September 13, 2025 | New York Red Bulls 1 at Portland Timbers 2 | Final |
| September 13, 2025 | Minnesota United FC 3 at San Diego FC 1 | Final |
| September 16, 2025 | Seattle Sounders FC 1 at Inter Miami CF 3 | Final |
| September 17, 2025 | Columbus Crew SC 2 at New York City FC 3 | Final |
| September 17, 2025 | Los Angeles FC 4 at Real Salt Lake 1 | Final |
| September 20, 2025 | Charlotte FC 0 at New York City FC 2 | Final |
| September 20, 2025 | New England Revolution 0 at Philadelphia Union 1 | Final |
| September 20, 2025 | San Diego FC 1 at Atlanta United FC 1 | Final |
| September 20, 2025 | New York Red Bulls 2 at Club de Foot Montreal 0 | Final |
| September 20, 2025 | Toronto FC 1 at Columbus Crew SC 1 | Final |
| September 20, 2025 | D.C. United 2 at Inter Miami CF 3 | Final |
| September 20, 2025 | Nashville SC 2 at Orlando City SC 3 | Final |
| September 20, 2025 | Colorado Rapids 1 at FC Dallas 3 | Final |
| September 20, 2025 | Portland Timbers 0 at Houston Dynamo FC 1 | Final |
| September 20, 2025 | Chicago Fire FC 3 at Minnesota United FC 0 | Final |
| September 20, 2025 | Vancouver Whitecaps FC 2 at Sporting Kansas City 0 | Final |
| September 20, 2025 | FC Cincinnati 3 at LA Galaxy 2 | Final |
| September 20, 2025 | St. Louis City SC 3 at San Jose Earthquakes 1 | Final |
| September 21, 2025 | Seattle Sounders FC 1 at Austin FC 2 | Final |
| September 21, 2025 | Real Salt Lake 1 at Los Angeles FC 4 | Final |
| September 24, 2025 | Inter Miami CF 4 at New York City FC 0 | Final |
| September 24, 2025 | Portland Timbers 1 at Vancouver Whitecaps FC 1 | Final |
| September 27, 2025 | Inter Miami CF 1 at Toronto FC 1 | Final |
| September 27, 2025 | Club de Foot Montreal 4 at Charlotte FC 1 | Final |
| September 27, 2025 | Philadelphia Union 6 at D.C. United 0 | Final |
| September 27, 2025 | Atlanta United FC 0 at New England Revolution 2 | Final |
| September 27, 2025 | New York City FC 3 at New York Red Bulls 2 | Final |
| September 27, 2025 | Columbus Crew SC 0 at Chicago Fire FC 2 | Final |
| September 27, 2025 | Houston Dynamo FC 1 at Nashville SC 3 | Final |
| September 27, 2025 | Los Angeles FC 3 at St. Louis City SC 0 | Final |
| September 27, 2025 | Minnesota United FC 1 at Colorado Rapids 1 | Final |
| September 27, 2025 | Austin FC 1 at Real Salt Lake 3 | Final |
| September 27, 2025 | Sporting Kansas City 1 at LA Galaxy 4 | Final |
| September 27, 2025 | FC Dallas 2 at Portland Timbers 2 | Final |
| September 27, 2025 | San Jose Earthquakes 1 at San Diego FC 0 | Final |
| September 27, 2025 | Vancouver Whitecaps FC 2 at Seattle Sounders FC 2 | Final |
| September 28, 2025 | Orlando City SC 1 at FC Cincinnati 1 | Final |
| September 30, 2025 | Chicago Fire FC 5 at Inter Miami CF 3 | Final |
| October 4, 2025 | Nashville SC 1 at Club de Foot Montreal 1 | Final |
| October 4, 2025 | Charlotte FC 1 at D.C. United 0 | Final |
| October 4, 2025 | LA Galaxy 1 at FC Dallas 2 | Final |
| October 4, 2025 | New England Revolution 1 at Inter Miami CF 4 | Final |
| October 4, 2025 | FC Cincinnati 1 at New York Red Bulls 0 | Final |
| October 4, 2025 | Columbus Crew SC 1 at Orlando City SC 1 | Final |
| October 4, 2025 | New York City FC 0 at Philadelphia Union 1 | Final |
| October 4, 2025 | St. Louis City SC 3 at Austin FC 1 | Final |
| October 4, 2025 | Toronto FC 2 at Chicago Fire FC 2 | Final |
| October 4, 2025 | San Diego FC 4 at Houston Dynamo FC 2 | Final |
| October 4, 2025 | Sporting Kansas City 0 at Minnesota United FC 3 | Final |
| October 4, 2025 | Colorado Rapids 0 at Real Salt Lake 1 | Final |
| October 4, 2025 | Portland Timbers 0 at Seattle Sounders FC 1 | Final |
| October 5, 2025 | Atlanta United FC 0 at Los Angeles FC 1 | Final |
| October 5, 2025 | San Jose Earthquakes 1 at Vancouver Whitecaps FC 4 | Final |
| October 8, 2025 | Toronto FC 0 at Los Angeles FC 2 | Final |
| October 11, 2025 | Atlanta United FC 0 at Inter Miami CF 4 | Final |
| October 11, 2025 | Vancouver Whitecaps FC 2 at Orlando City SC 1 | Final |
| October 11, 2025 | Real Salt Lake 0 at Seattle Sounders FC 1 | Final |
| October 11, 2025 | FC Dallas 1 at LA Galaxy 2 | Final |
| October 12, 2025 | Los Angeles FC 0 at Austin FC 1 | Final |
| October 18, 2025 | D.C. United 1 at Atlanta United FC 1 | Final |
| October 18, 2025 | Philadelphia Union 0 at Charlotte FC 2 | Final |
| October 18, 2025 | New York Red Bulls 1 at Columbus Crew SC 3 | Final |
| October 18, 2025 | Club de Foot Montreal 0 at FC Cincinnati 3 | Final |
| October 18, 2025 | Inter Miami CF 5 at Nashville SC 2 | Final |
| October 18, 2025 | Chicago Fire FC 2 at New England Revolution 2 | Final |
| October 18, 2025 | Seattle Sounders FC 2 at New York City FC 1 | Final |
| October 18, 2025 | Orlando City SC 2 at Toronto FC 4 | Final |
| October 18, 2025 | Los Angeles FC 2 at Colorado Rapids 2 | Final |
| October 18, 2025 | Minnesota United FC 1 at LA Galaxy 2 | Final |
| October 18, 2025 | San Diego FC 4 at Portland Timbers 0 | Final |
| October 18, 2025 | Austin FC 1 at San Jose Earthquakes 2 | Final |
| October 18, 2025 | Houston Dynamo FC 0 at Sporting Kansas City 0 | Final |
| October 18, 2025 | Real Salt Lake 2 at St. Louis City SC 2 | Final |
| October 18, 2025 | FC Dallas 2 at Vancouver Whitecaps FC 1 | Final |
| October 22, 2025 | Orlando City SC 1 at Chicago Fire FC 3 (Playoff) | Final |
| October 22, 2025 | Real Salt Lake 1 at Portland Timbers 3 (Playoff) | Final |
| October 24, 2025 | Nashville SC 1 at Inter Miami CF 3 (Playoff Gm. 1) | Final |
| October 26, 2025 | Chicago Fire FC 2 at Philadelphia Union 2 (Playoff Gm. 1) | Final (PK 2-4) |
| October 26, 2025 | FC Dallas 0 at Vancouver Whitecaps FC 3 (Playoff Gm. 1) | Final |
| October 26, 2025 | Portland Timbers 1 at San Diego FC 2 (Playoff Gm. 1) | Final |
| October 27, 2025 | Columbus Crew SC 0 at FC Cincinnati 1 (Playoff Gm. 1) | Final |
| October 27, 2025 | Seattle Sounders FC 0 at Minnesota United FC 0 (Playoff Gm. 1) | Final (PK 2-3) |
| October 28, 2025 | New York City FC 1 at Charlotte FC 0 (Playoff Gm. 1) | Final |
| October 29, 2025 | Austin FC 1 at Los Angeles FC 2 (Playoff Gm. 1) | Final |
| November 1, 2025 | Charlotte FC 0 at New York City FC 0 (Playoff Gm. 2) | Final (PK 7-6) |
| November 1, 2025 | Philadelphia Union 3 at Chicago Fire FC 0 (Playoff Gm. 2) | Final |
| November 1, 2025 | Inter Miami CF 1 at Nashville SC 2 (Playoff Gm. 2) | Final |
| November 1, 2025 | Vancouver Whitecaps FC 1 at FC Dallas 1 (Playoff Gm. 2) | Final (PK 4-2) |
| November 1, 2025 | San Diego FC 2 at Portland Timbers 2 (Playoff Gm. 2) | Final (PK 2-3) |
| November 2, 2025 | FC Cincinnati at Columbus Crew SC (Playoff Gm. 2) | 7:30 p.m. |
| November 2, 2025 | Los Angeles FC at Austin FC (Playoff Gm. 2) | 9:30 p.m. |
| November 3, 2025 | Minnesota United FC at Seattle Sounders FC (Playoff Gm. 2) | 11:30 p.m. |
| November 7, 2025 | New York City FC at Charlotte FC (Playoff Gm. 3, if nec.) | 1:00 p.m. |
| November 8, 2025 | Columbus Crew SC at FC Cincinnati (Playoff Gm. 3, if nec.) | 1:00 p.m. |
| November 8, 2025 | Nashville SC at Inter Miami CF (Playoff Gm. 3) | 1:00 p.m. |
| November 8, 2025 | Austin FC at Los Angeles FC (Playoff Gm. 3, if nec.) | 1:00 p.m. |
| November 8, 2025 | Seattle Sounders FC at Minnesota United FC (Playoff Gm. 3, if nec.) | 1:00 p.m. |
| November 9, 2025 | Portland Timbers at San Diego FC (Playoff Gm. 3, if nec.) | |
Major League Soccer Schedule
