| | | |
| March 8, 2025 | Hartford Athletic 0 at Lexington Sporting Club 2 | Final |
| March 8, 2025 | Detroit City FC 2 at Miami FC 0 | Final |
| March 8, 2025 | Pittsburgh Riverhounds SC 1 at North Carolina FC 1 | Final |
| March 8, 2025 | Louisville City FC 2 at Charleston Battery 1 | Final |
| March 8, 2025 | Loudoun United FC 3 at Birmingham Legion FC 1 | Final |
| March 8, 2025 | Monterey Bay FC 0 at San Antonio FC 1 | Final |
| March 8, 2025 | Colorado Springs Switchbacks FC 2 at El Paso Locomotive FC 2 | Final |
| March 8, 2025 | FC Tulsa 1 at Phoenix Rising FC 0 | Final |
| March 8, 2025 | Oakland Roots 2 at Orange County SC 4 | Final |
| March 8, 2025 | New Mexico United 1 at Sacramento Republic FC 2 | Final |
| March 8, 2025 | Tampa Bay Rowdies 0 at Las Vegas Lights FC 1 | Final |
| March 15, 2025 | Detroit City FC 2 at Colorado Springs Switchbacks FC 1 | Final |
| March 15, 2025 | Indy Eleven 3 at Miami FC 1 | Final |
| March 15, 2025 | Loudoun United FC 2 at North Carolina FC 1 | Final |
| March 15, 2025 | Rhode Island FC 0 at Charleston Battery 2 | Final |
| March 15, 2025 | Tampa Bay Rowdies 0 at FC Tulsa 1 | Final |
| March 15, 2025 | Pittsburgh Riverhounds SC 0 at San Antonio FC 2 | Final |
| March 15, 2025 | Phoenix Rising FC 4 at El Paso Locomotive FC 4 | Final |
| March 15, 2025 | Oakland Roots 2 at Monterey Bay FC 3 | Final |
| March 15, 2025 | New Mexico United 3 at Las Vegas Lights FC 2 | Final |
| March 15, 2025 | Lexington Sporting Club 2 at Orange County SC 2 | Final |
| March 16, 2025 | Louisville City FC 1 at Birmingham Legion FC 1 | Final |
| March 22, 2025 | Birmingham Legion FC 2 at Detroit City FC 2 | Final |
| March 22, 2025 | Loudoun United FC 0 at Louisville City FC 2 | Final |
| March 22, 2025 | El Paso Locomotive FC 0 at New Mexico United 1 | Final |
| March 22, 2025 | Indy Eleven 1 at Lexington Sporting Club 1 | Final |
| March 22, 2025 | Tampa Bay Rowdies 2 at Miami FC 1 | Final |
| March 22, 2025 | Hartford Athletic 0 at Pittsburgh Riverhounds SC 1 | Final |
| March 22, 2025 | North Carolina FC 1 at FC Tulsa 0 | Final |
| March 22, 2025 | San Antonio FC 2 at Oakland Roots 1 | Final |
| March 22, 2025 | Monterey Bay FC 3 at Orange County SC 0 | Final |
| March 22, 2025 | Rhode Island FC 2 at Phoenix Rising FC 2 | Final |
| March 22, 2025 | Colorado Springs Switchbacks FC 2 at Sacramento Republic FC 2 | Final |
| March 28, 2025 | Sacramento Republic FC 0 at FC Tulsa 1 | Final |
| March 29, 2025 | El Paso Locomotive FC 2 at Hartford Athletic 1 | Final |
| March 29, 2025 | Rhode Island FC 0 at Loudoun United FC 2 | Final |
| March 29, 2025 | Detroit City FC 0 at Louisville City FC 2 | Final |
| March 29, 2025 | Colorado Springs Switchbacks FC 3 at Indy Eleven 2 | Final |
| March 29, 2025 | San Antonio FC 3 at Lexington Sporting Club 2 | Final |
| March 29, 2025 | New Mexico United 1 at Miami FC 0 | Final |
| March 29, 2025 | Charleston Battery 1 at North Carolina FC 2 | Final |
| March 29, 2025 | Birmingham Legion FC 0 at Pittsburgh Riverhounds SC 2 | Final |
| March 29, 2025 | Phoenix Rising FC 1 at Monterey Bay FC 3 | Final |
| March 29, 2025 | Las Vegas Lights FC 0 at Oakland Roots 0 | Final |
| April 5, 2025 | Monterey Bay FC 0 at Detroit City FC 0 | Final |
| April 5, 2025 | Rhode Island FC 3 at Oakland Roots 0 | Final |
| April 5, 2025 | Hartford Athletic 0 at Loudoun United FC 2 | Final |
| April 5, 2025 | Tampa Bay Rowdies 1 at Charleston Battery 2 | Final |
| April 5, 2025 | North Carolina FC 2 at Indy Eleven 2 | Final |
| April 5, 2025 | Lexington Sporting Club 1 at El Paso Locomotive FC 2 | Final |
| April 5, 2025 | Louisville City FC 1 at Sacramento Republic FC 1 | Final |
| April 5, 2025 | Orange County SC 0 at Las Vegas Lights FC 1 | Final |
| April 6, 2025 | Phoenix Rising FC 2 at San Antonio FC 1 | Final |
| April 12, 2025 | Indy Eleven at Hartford Athletic | Ppd. |
| April 12, 2025 | Las Vegas Lights FC 0 at Lexington Sporting Club 0 | Final |
| April 12, 2025 | Pittsburgh Riverhounds SC 1 at Charleston Battery 2 | Final |
| April 12, 2025 | Loudoun United FC 2 at Tampa Bay Rowdies 1 | Final |
| April 12, 2025 | Oakland Roots 2 at FC Tulsa 1 | Final |
| April 12, 2025 | Miami FC 2 at San Antonio FC 1 | Final |
| April 12, 2025 | North Carolina FC 0 at New Mexico United 1 | Final |
| April 12, 2025 | Colorado Springs Switchbacks FC 1 at Monterey Bay FC 2 | Final |
| April 12, 2025 | Sacramento Republic FC 1 at Orange County SC 2 | Final |
| April 12, 2025 | Detroit City FC 3 at Phoenix Rising FC 2 | Final |
| April 13, 2025 | El Paso Locomotive FC 1 at Birmingham Legion FC 3 | Final |
| April 19, 2025 | Rhode Island FC 0 at Detroit City FC 2 | Final |
| April 19, 2025 | Birmingham Legion FC 0 at Hartford Athletic 1 | Final |
| April 19, 2025 | Orange County SC 0 at Oakland Roots 2 | Final |
| April 19, 2025 | Sacramento Republic FC 2 at Phoenix Rising FC 2 | Final |
| April 19, 2025 | Pittsburgh Riverhounds SC 1 at Loudoun United FC 2 | Final |
| April 19, 2025 | Charleston Battery 3 at Indy Eleven 1 | Final |
| April 19, 2025 | Monterey Bay FC 0 at Lexington Sporting Club 0 | Final |
| April 19, 2025 | North Carolina FC 1 at Miami FC 2 | Final |
| April 19, 2025 | Louisville City FC 2 at Tampa Bay Rowdies 1 | Final |
| April 19, 2025 | El Paso Locomotive FC 1 at Colorado Springs Switchbacks FC 1 | Final |
| April 19, 2025 | FC Tulsa 4 at Las Vegas Lights FC 1 | Final |
| April 23, 2025 | Colorado Springs Switchbacks FC 2 at San Antonio FC 3 | Final |
| April 23, 2025 | Monterey Bay FC 0 at New Mexico United 1 | Final |
| April 25, 2025 | Charlotte Independence 2 at North Carolina FC 1 (Jagermeister Cup) | Final |
| April 26, 2025 | Pittsburgh Riverhounds SC 0 at Detroit City FC 1 (Jagermeister Cup) | Final |
| April 26, 2025 | Portland Hearts of Pine 0 at Hartford Athletic 2 (Jagermeister Cup) | Final |
| April 26, 2025 | Loudoun United FC 1 at Lexington Sporting Club 0 (Jagermeister Cup) | Final |
| April 26, 2025 | Charleston Battery 0 at FC Naples 1 (Jagermeister Cup) | Final |
| April 26, 2025 | Indy Eleven 4 at Forward Madison FC 0 (Jagermeister Cup) | Final |
| April 26, 2025 | FC Tulsa 2 at One Knoxville SC 2 (Jagermeister Cup) | Final |
| April 26, 2025 | Richmond Kickers 1 at Louisville City FC 4 (Jagermeister Cup) | Final |
| April 26, 2025 | Miami FC 3 at Tampa Bay Rowdies 3 (Jagermeister Cup) | Final |
| April 26, 2025 | El Paso Locomotive FC 0 at Texoma FC 0 (Jagermeister Cup) | Final |
| April 26, 2025 | Union Omaha 0 at New Mexico United 2 (Jagermeister Cup) | Final |
| April 26, 2025 | Las Vegas Lights FC 3 at Orange County SC 1 (Jagermeister Cup) | Final |
| April 26, 2025 | San Antonio FC 1 at Phoenix Rising FC 0 (Jagermeister Cup) | Final |
| April 26, 2025 | AV Alta FC 0 at Sacramento Republic FC 1 (Jagermeister Cup) | Final |
| April 27, 2025 | Rhode Island FC 4 at Westchester SC 1 (Jagermeister Cup) | Final |
| April 27, 2025 | Chattanooga Red Wolves SC 1 at Birmingham Legion FC 3 (Jagermeister Cup) | Final |
| April 27, 2025 | Oakland Roots 1 at Spokane Velocity FC 2 (Jagermeister Cup) | Final |
| April 30, 2025 | AV Alta FC 1 at Las Vegas Lights FC 2 (Jagermeister Cup) | Final |
| May 1, 2025 | Lexington Sporting Club 0 at Louisville City FC 2 | Final |
| May 3, 2025 | San Antonio FC 0 at Rhode Island FC 0 | Final |
| May 3, 2025 | Hartford Athletic 2 at Charleston Battery 4 | Final |
| May 3, 2025 | Detroit City FC 2 at Indy Eleven 2 | Final |
| May 3, 2025 | North Carolina FC 2 at Pittsburgh Riverhounds SC 0 | Final |
| May 3, 2025 | Birmingham Legion FC 2 at Tampa Bay Rowdies 2 | Final |
| May 3, 2025 | Phoenix Rising FC 1 at Colorado Springs Switchbacks FC 1 | Final |
| May 3, 2025 | New Mexico United 0 at El Paso Locomotive FC 3 | Final |
| May 3, 2025 | FC Tulsa 1 at Orange County SC 2 | Final |
| May 3, 2025 | Loudoun United FC 0 at Las Vegas Lights FC 1 | Final |
| May 4, 2025 | Miami FC 1 at Monterey Bay FC 1 | Final |
| May 4, 2025 | Sacramento Republic FC 1 at Oakland Roots 0 | Final |
| May 9, 2025 | Orange County SC at North Carolina FC | 7:00 p.m. |
| May 10, 2025 | Monterey Bay FC at Rhode Island FC | 4:00 p.m. |
| May 10, 2025 | Lexington Sporting Club at Loudoun United FC | 6:00 p.m. |
| May 10, 2025 | Detroit City FC at Hartford Athletic | 7:00 p.m. |
| May 10, 2025 | Pittsburgh Riverhounds SC at Louisville City FC | 7:30 p.m. |
| May 10, 2025 | Charleston Battery at Tampa Bay Rowdies | 7:30 p.m. |
| May 10, 2025 | El Paso Locomotive FC at FC Tulsa | 8:00 p.m. |
| May 10, 2025 | Oakland Roots at San Antonio FC | 8:30 p.m. |
| May 10, 2025 | Phoenix Rising FC at New Mexico United | 9:00 p.m. |
| May 10, 2025 | Indy Eleven at Sacramento Republic FC | 10:00 p.m. |
| May 10, 2025 | Colorado Springs Switchbacks FC at Las Vegas Lights FC | 10:30 p.m. |
| May 14, 2025 | Rhode Island FC at Birmingham Legion FC | 8:00 p.m. |
| May 16, 2025 | Oakland Roots at North Carolina FC | 7:00 p.m. |
| May 16, 2025 | Indy Eleven at El Paso Locomotive FC | 9:00 p.m. |
| May 17, 2025 | Louisville City FC at Hartford Athletic | 7:00 p.m. |
| May 17, 2025 | Loudoun United FC at Miami FC | 7:00 p.m. |
| May 17, 2025 | San Antonio FC at Charleston Battery | 7:30 p.m. |
| May 17, 2025 | Rhode Island FC at Tampa Bay Rowdies | 7:30 p.m. |
| May 17, 2025 | Pittsburgh Riverhounds SC at Colorado Springs Switchbacks FC | 9:00 p.m. |
| May 17, 2025 | New Mexico United at Orange County SC | 10:00 p.m. |
| May 17, 2025 | Monterey Bay FC at Phoenix Rising FC | 10:00 p.m. |
| May 17, 2025 | Las Vegas Lights FC at Sacramento Republic FC | 10:00 p.m. |
| May 18, 2025 | Detroit City FC at Birmingham Legion FC | 5:00 p.m. |
| May 18, 2025 | FC Tulsa at Lexington Sporting Club | 7:00 p.m. |
| May 24, 2025 | Charleston Battery at Detroit City FC | 4:00 p.m. |
| May 24, 2025 | Pittsburgh Riverhounds SC at Rhode Island FC | 4:00 p.m. |
| May 24, 2025 | Tampa Bay Rowdies at Lexington Sporting Club | 7:00 p.m. |
| May 24, 2025 | Birmingham Legion FC at Miami FC | 7:00 p.m. |
| May 24, 2025 | Indy Eleven at One Knoxville SC | 7:00 p.m. |
| May 24, 2025 | Louisville City FC at Monterey Bay FC | 10:00 p.m. |
| May 24, 2025 | New Mexico United at Oakland Roots | 10:00 p.m. |
| May 24, 2025 | Colorado Springs Switchbacks FC at Orange County SC | 10:00 p.m. |
| May 24, 2025 | El Paso Locomotive FC at Las Vegas Lights FC | 10:30 p.m. |
| May 28, 2025 | Hartford Athletic at Indy Eleven | 7:00 p.m. |
| May 28, 2025 | FC Tulsa at San Antonio FC | 8:30 p.m. |
| May 28, 2025 | Spokane Velocity FC at Monterey Bay FC | 10:00 p.m. |
| May 28, 2025 | Phoenix Rising FC at Las Vegas Lights FC | 10:30 p.m. |
| May 31, 2025 | Hartford Athletic at Westchester SC | 4:00 p.m. |
| May 31, 2025 | Greenville Triumph SC at Charleston Battery | 6:00 p.m. |
| May 31, 2025 | Louisville City FC at Loudoun United FC | 6:00 p.m. |
| May 31, 2025 | Detroit City FC at Portland Hearts of Pine | 6:00 p.m. |
| May 31, 2025 | FC Naples at Miami FC | 7:00 p.m. |
| May 31, 2025 | Rhode Island FC at Pittsburgh Riverhounds SC | 7:00 p.m. |
| May 31, 2025 | Lexington Sporting Club at Charlotte Independence | 7:00 p.m. |
| May 31, 2025 | North Carolina FC at Richmond Kickers | 7:00 p.m. |
| May 31, 2025 | South Georgia Tormenta FC at Tampa Bay Rowdies | 7:30 p.m. |
| May 31, 2025 | Birmingham Legion FC at FC Tulsa | 8:30 p.m. |
| May 31, 2025 | Colorado Springs Switchbacks FC at El Paso Locomotive FC | 9:00 p.m. |
| May 31, 2025 | Orange County SC at Monterey Bay FC | 10:00 p.m. |
| May 31, 2025 | New Mexico United at Phoenix Rising FC | 10:00 p.m. |
| May 31, 2025 | Las Vegas Lights FC at Sacramento Republic FC | 10:00 p.m. |
| May 31, 2025 | Oakland Roots at AV Alta FC | 10:30 p.m. |
| June 4, 2025 | Indy Eleven at Birmingham Legion FC | 8:00 p.m. |
| June 7, 2025 | Charleston Battery at Loudoun United FC | 6:00 p.m. |
| June 7, 2025 | North Carolina FC at Hartford Athletic | 7:00 p.m. |
| June 7, 2025 | Detroit City FC at Pittsburgh Riverhounds SC | 7:00 p.m. |
| June 7, 2025 | Miami FC at Rhode Island FC | 7:00 p.m. |
| June 7, 2025 | Tampa Bay Rowdies at Louisville City FC | 8:00 p.m. |
| June 7, 2025 | Colorado Springs Switchbacks FC at New Mexico United | 9:00 p.m. |
| June 7, 2025 | Las Vegas Lights FC at San Antonio FC | 9:00 p.m. |
| June 7, 2025 | Lexington Sporting Club at Monterey Bay FC | 10:00 p.m. |
| June 7, 2025 | El Paso Locomotive FC at Oakland Roots | 10:00 p.m. |
| June 7, 2025 | Orange County SC at Phoenix Rising FC | 10:30 p.m. |
| June 7, 2025 | FC Tulsa at Sacramento Republic FC | 11:00 p.m. |
| June 11, 2025 | Rhode Island FC at Louisville City FC | 8:00 p.m. |
| June 14, 2025 | Detroit City FC at Loudoun United FC | 6:00 p.m. |
| June 14, 2025 | Charleston Battery at Hartford Athletic | 7:00 p.m. |
| June 14, 2025 | Pittsburgh Riverhounds SC at Indy Eleven | 7:00 p.m. |
| June 14, 2025 | New Mexico United at Lexington Sporting Club | 7:00 p.m. |
| June 14, 2025 | North Carolina FC at Rhode Island FC | 7:00 p.m. |
| June 14, 2025 | Miami FC at Tampa Bay Rowdies | 7:30 p.m. |
| June 14, 2025 | Birmingham Legion FC at Louisville City FC | 8:00 p.m. |
| June 14, 2025 | Phoenix Rising FC at FC Tulsa | 8:30 p.m. |
| June 14, 2025 | Oakland Roots at Colorado Springs Switchbacks FC | 9:00 p.m. |
| June 14, 2025 | Orange County SC at El Paso Locomotive FC | 9:00 p.m. |
| June 14, 2025 | Monterey Bay FC at Las Vegas Lights FC | 10:30 p.m. |
| June 14, 2025 | San Antonio FC at Sacramento Republic FC | 11:00 p.m. |
| June 18, 2025 | Charleston Battery at Miami FC | 7:00 p.m. |
| June 18, 2025 | Sacramento Republic FC at Birmingham Legion FC | 8:00 p.m. |
| June 20, 2025 | Loudoun United FC at Hartford Athletic | 7:30 p.m. |
| June 20, 2025 | Louisville City FC at North Carolina FC | 7:30 p.m. |
| June 21, 2025 | Miami FC at Detroit City FC | 4:00 p.m. |
| June 21, 2025 | Las Vegas Lights FC at Indy Eleven | 7:00 p.m. |
| June 21, 2025 | Colorado Springs Switchbacks FC at Lexington Sporting Club | 7:00 p.m. |
| June 21, 2025 | Tampa Bay Rowdies at Pittsburgh Riverhounds SC | 7:00 p.m. |
| June 21, 2025 | Sacramento Republic FC at Rhode Island FC | 7:00 p.m. |
| June 21, 2025 | Phoenix Rising FC at Charleston Battery | 7:30 p.m. |
| June 21, 2025 | Oakland Roots at Birmingham Legion FC | 8:00 p.m. |
| June 21, 2025 | San Antonio FC at New Mexico United | 9:00 p.m. |
| June 21, 2025 | El Paso Locomotive FC at Monterey Bay FC | 10:00 p.m. |
| June 25, 2025 | Louisville City FC at Loudoun United FC | 6:00 p.m. |
| June 25, 2025 | Indy Eleven at Tampa Bay Rowdies | 7:30 p.m. |
| June 25, 2025 | San Antonio FC at Colorado Springs Switchbacks FC | 9:00 p.m. |
| June 28, 2025 | Charlotte Independence at Loudoun United FC | 6:00 p.m. |
| June 28, 2025 | Detroit City FC at Hartford Athletic | 7:00 p.m. |
| June 28, 2025 | Birmingham Legion FC at Indy Eleven | 7:00 p.m. |
| June 28, 2025 | Westchester SC at Pittsburgh Riverhounds SC | 7:00 p.m. |
| June 28, 2025 | Portland Hearts of Pine at Rhode Island FC | 7:00 p.m. |
| June 28, 2025 | Miami FC at Greenville Triumph SC | 7:00 p.m. |
| June 28, 2025 | Lexington Sporting Club at Richmond Kickers | 7:00 p.m. |
| June 28, 2025 | Charleston Battery at South Georgia Tormenta FC | 7:30 p.m. |
| June 28, 2025 | North Carolina FC at Louisville City FC | 8:00 p.m. |
| June 28, 2025 | Chattanooga Red Wolves SC at FC Tulsa | 8:30 p.m. |
| June 28, 2025 | Phoenix Rising FC at Texoma FC | 8:30 p.m. |
| June 28, 2025 | Colorado Springs Switchbacks FC at New Mexico United | 9:00 p.m. |
| June 28, 2025 | Union Omaha at San Antonio FC | 9:00 p.m. |
| June 28, 2025 | Monterey Bay FC at Oakland Roots | 10:00 p.m. |
| June 28, 2025 | Sacramento Republic FC at Orange County SC | 10:00 p.m. |
| June 28, 2025 | Spokane Velocity FC at Las Vegas Lights FC | 10:30 p.m. |
| July 2, 2025 | Charleston Battery at Birmingham Legion FC | 8:00 p.m. |
| July 3, 2025 | Orange County SC at Loudoun United FC | 7:00 p.m. |
| July 4, 2025 | New Mexico United at Pittsburgh Riverhounds SC | 7:00 p.m. |
| July 4, 2025 | Tampa Bay Rowdies at FC Naples | 8:00 p.m. |
| July 4, 2025 | Louisville City FC at Colorado Springs Switchbacks FC | 9:00 p.m. |
| July 4, 2025 | San Antonio FC at El Paso Locomotive FC | 9:00 p.m. |
| July 4, 2025 | Sacramento Republic FC at Las Vegas Lights FC | 10:30 p.m. |
| July 4, 2025 | Lexington Sporting Club at Phoenix Rising FC | 10:30 p.m. |
| July 5, 2025 | FC Tulsa at Miami FC | 7:00 p.m. |
| July 5, 2025 | Birmingham Legion FC at Rhode Island FC | 7:00 p.m. |
| July 5, 2025 | North Carolina FC at Charleston Battery | 7:30 p.m. |
| July 5, 2025 | Monterey Bay FC at Indy Eleven | 7:30 p.m. |
| July 5, 2025 | Detroit City FC at Oakland Roots | 10:00 p.m. |
| July 11, 2025 | Birmingham Legion FC at North Carolina FC | 7:30 p.m. |
| July 12, 2025 | Hartford Athletic at Detroit City FC | 7:00 p.m. |
| July 12, 2025 | Rhode Island FC at Indy Eleven | 7:00 p.m. |
| July 12, 2025 | Lexington Sporting Club at Miami FC | 7:00 p.m. |
| July 12, 2025 | Las Vegas Lights FC at FC Tulsa | 8:30 p.m. |
| July 12, 2025 | Charleston Battery at New Mexico United | 9:00 p.m. |
| July 12, 2025 | Tampa Bay Rowdies at San Antonio FC | 9:00 p.m. |
| July 12, 2025 | Orange County SC at Monterey Bay FC | 10:00 p.m. |
| July 12, 2025 | Phoenix Rising FC at Oakland Roots | 10:00 p.m. |
| July 12, 2025 | El Paso Locomotive FC at Sacramento Republic FC | 11:00 p.m. |
| July 13, 2025 | Loudoun United FC at Pittsburgh Riverhounds SC | 5:00 p.m. |
| July 16, 2025 | Tampa Bay Rowdies at Hartford Athletic | 7:30 p.m. |
| July 16, 2025 | Monterey Bay FC at FC Tulsa | 8:30 p.m. |
| July 18, 2025 | Indy Eleven at North Carolina FC | 7:30 p.m. |
| July 19, 2025 | Hartford Athletic at Rhode Island FC | 4:00 p.m. |
| July 19, 2025 | Pittsburgh Riverhounds SC at Detroit City FC | 7:00 p.m. |
| July 19, 2025 | Oakland Roots at Loudoun United FC | 7:00 p.m. |
| July 19, 2025 | Miami FC at Charleston Battery | 7:30 p.m. |
| July 19, 2025 | Colorado Springs Switchbacks FC at Birmingham Legion FC | 8:00 p.m. |
| July 19, 2025 | FC Tulsa at Louisville City FC | 8:00 p.m. |
| July 19, 2025 | Phoenix Rising FC at El Paso Locomotive FC | 9:00 p.m. |
| July 19, 2025 | Las Vegas Lights FC at Orange County SC | 10:00 p.m. |
| July 19, 2025 | Lexington Sporting Club at Sacramento Republic FC | 11:00 p.m. |
| July 25, 2025 | Pittsburgh Riverhounds SC at Portland Hearts of Pine | 6:30 p.m. |
| July 26, 2025 | Orange County SC at Oakland Roots | 4:00 p.m. |
| July 26, 2025 | Westchester SC at Detroit City FC | 7:00 p.m. |
| July 26, 2025 | FC Tulsa at Indy Eleven | 7:00 p.m. |
| July 26, 2025 | Louisville City FC at Lexington Sporting Club | 7:00 p.m. |
| July 26, 2025 | South Georgia Tormenta FC at Miami FC | 7:00 p.m. |
| July 26, 2025 | Hartford Athletic at Rhode Island FC | 7:00 p.m. |
| July 26, 2025 | Tampa Bay Rowdies at Charleston Battery | 7:30 p.m. |
| July 26, 2025 | Loudoun United FC at North Carolina FC | 7:30 p.m. |
| July 26, 2025 | Forward Madison FC at Birmingham Legion FC | 8:00 p.m. |
| July 26, 2025 | El Paso Locomotive FC at Union Omaha | 8:00 p.m. |
| July 26, 2025 | Texoma FC at Colorado Springs Switchbacks FC | 9:00 p.m. |
| July 26, 2025 | New Mexico United at San Antonio FC | 9:00 p.m. |
| July 26, 2025 | Sacramento Republic FC at Spokane Velocity FC | 10:00 p.m. |
| July 26, 2025 | Monterey Bay FC at AV Alta FC | 11:00 p.m. |
| July 29, 2025 | Miami FC at Pittsburgh Riverhounds SC | 7:00 p.m. |
| July 30, 2025 | New Mexico United at Hartford Athletic | 7:30 p.m. |
| July 30, 2025 | Phoenix Rising FC at Orange County SC | 10:00 p.m. |
| August 1, 2025 | Loudoun United FC at FC Tulsa | 8:30 p.m. |
| August 1, 2025 | Lexington Sporting Club at Colorado Springs Switchbacks FC | 9:00 p.m. |
| August 2, 2025 | Tampa Bay Rowdies at Indy Eleven | 7:00 p.m. |
| August 2, 2025 | Rhode Island FC at Pittsburgh Riverhounds SC | 7:00 p.m. |
| August 2, 2025 | North Carolina FC at Louisville City FC | 8:00 p.m. |
| August 2, 2025 | Las Vegas Lights FC at El Paso Locomotive FC | 9:00 p.m. |
| August 2, 2025 | Sacramento Republic FC at San Antonio FC | 9:00 p.m. |
| August 2, 2025 | Birmingham Legion FC at Phoenix Rising FC | 10:30 p.m. |
| August 6, 2025 | Detroit City FC at Rhode Island FC | 7:00 p.m. |
| August 6, 2025 | Miami FC at Hartford Athletic | 7:30 p.m. |
| August 6, 2025 | FC Tulsa at Monterey Bay FC | 10:00 p.m. |
| August 9, 2025 | Phoenix Rising FC at Lexington Sporting Club | 6:00 p.m. |
| August 9, 2025 | Indy Eleven at Detroit City FC | 7:00 p.m. |
| August 9, 2025 | El Paso Locomotive FC at Miami FC | 7:00 p.m. |
| August 9, 2025 | Orange County SC at Pittsburgh Riverhounds SC | 7:00 p.m. |
| August 9, 2025 | Loudoun United FC at Rhode Island FC | 7:00 p.m. |
| August 9, 2025 | Tampa Bay Rowdies at North Carolina FC | 7:30 p.m. |
| August 9, 2025 | Hartford Athletic at Birmingham Legion FC | 8:00 p.m. |
| August 9, 2025 | Charleston Battery at Louisville City FC | 8:00 p.m. |
| August 9, 2025 | New Mexico United at FC Tulsa | 8:30 p.m. |
| August 9, 2025 | Colorado Springs Switchbacks FC at Oakland Roots | 10:00 p.m. |
| August 9, 2025 | San Antonio FC at Las Vegas Lights FC | 10:30 p.m. |
| August 9, 2025 | Monterey Bay FC at Sacramento Republic FC | 11:00 p.m. |
| August 15, 2025 | Detroit City FC at North Carolina FC | 7:30 p.m. |
| August 16, 2025 | FC Tulsa at Hartford Athletic | 7:00 p.m. |
| August 16, 2025 | Indy Eleven at Loudoun United FC | 7:00 p.m. |
| August 16, 2025 | Louisville City FC at Miami FC | 7:00 p.m. |
| August 16, 2025 | Charleston Battery at Pittsburgh Riverhounds SC | 7:00 p.m. |
| August 16, 2025 | Phoenix Rising FC at Tampa Bay Rowdies | 7:30 p.m. |
| August 16, 2025 | Orange County SC at Colorado Springs Switchbacks FC | 9:00 p.m. |
| August 16, 2025 | Monterey Bay FC at El Paso Locomotive FC | 9:00 p.m. |
| August 16, 2025 | Las Vegas Lights FC at New Mexico United | 9:00 p.m. |
| August 16, 2025 | Lexington Sporting Club at San Antonio FC | 9:00 p.m. |
| August 16, 2025 | Oakland Roots at Sacramento Republic FC | 11:00 p.m. |
| August 20, 2025 | San Antonio FC at Orange County SC | 10:00 p.m. |
| August 23, 2025 | Tampa Bay Rowdies at Detroit City FC | 7:00 p.m. |
| August 23, 2025 | Rhode Island FC at Hartford Athletic | 7:00 p.m. |
| August 23, 2025 | Miami FC at Indy Eleven | 7:00 p.m. |
| August 23, 2025 | Oakland Roots at Lexington Sporting Club | 7:00 p.m. |
| August 23, 2025 | Loudoun United FC at Charleston Battery | 7:30 p.m. |
| August 23, 2025 | Pittsburgh Riverhounds SC at Birmingham Legion FC | 8:00 p.m. |
| August 23, 2025 | New Mexico United at Louisville City FC | 8:00 p.m. |
| August 23, 2025 | Orange County SC at FC Tulsa | 8:30 p.m. |
| August 23, 2025 | Sacramento Republic FC at El Paso Locomotive FC | 9:00 p.m. |
| August 23, 2025 | San Antonio FC at Monterey Bay FC | 10:00 p.m. |
| August 23, 2025 | North Carolina FC at Las Vegas Lights FC | 10:30 p.m. |
| August 23, 2025 | Colorado Springs Switchbacks FC at Phoenix Rising FC | 10:30 p.m. |
| August 30, 2025 | San Antonio FC at Detroit City FC | 7:00 p.m. |
| August 30, 2025 | Louisville City FC at Indy Eleven | 7:00 p.m. |
| August 30, 2025 | Miami FC at Loudoun United FC | 7:00 p.m. |
| August 30, 2025 | Charleston Battery at Rhode Island FC | 7:00 p.m. |
| August 30, 2025 | Hartford Athletic at North Carolina FC | 7:30 p.m. |
| August 30, 2025 | Pittsburgh Riverhounds SC at Tampa Bay Rowdies | 7:30 p.m. |
| August 30, 2025 | FC Tulsa at Colorado Springs Switchbacks FC | 9:00 p.m. |
| August 30, 2025 | Sacramento Republic FC at New Mexico United | 9:00 p.m. |
| August 30, 2025 | Monterey Bay FC at Oakland Roots | 10:00 p.m. |
| August 30, 2025 | Birmingham Legion FC at Orange County SC | 10:00 p.m. |
| August 30, 2025 | Lexington Sporting Club at Las Vegas Lights FC | 10:30 p.m. |
| August 30, 2025 | El Paso Locomotive FC at Phoenix Rising FC | 10:30 p.m. |
| September 3, 2025 | Indy Eleven at Hartford Athletic | 7:30 p.m. |
| September 5, 2025 | North Carolina FC at Lexington Sporting Club | 7:00 p.m. |
| September 5, 2025 | Las Vegas Lights FC at Phoenix Rising FC | 10:30 p.m. |
| September 6, 2025 | Louisville City FC at Rhode Island FC | 4:00 p.m. |
| September 6, 2025 | Orange County SC at Detroit City FC | 7:00 p.m. |
| September 6, 2025 | Hartford Athletic at Miami FC | 7:00 p.m. |
| September 6, 2025 | Indy Eleven at Charleston Battery | 7:30 p.m. |
| September 6, 2025 | Sacramento Republic FC at Tampa Bay Rowdies | 7:30 p.m. |
| September 6, 2025 | Birmingham Legion FC at FC Tulsa | 8:30 p.m. |
| September 6, 2025 | New Mexico United at San Antonio FC | 8:30 p.m. |
| September 6, 2025 | Monterey Bay FC at Colorado Springs Switchbacks FC | 9:00 p.m. |
| September 6, 2025 | Loudoun United FC at El Paso Locomotive FC | 9:00 p.m. |
| September 6, 2025 | Pittsburgh Riverhounds SC at Oakland Roots | 10:00 p.m. |
| September 10, 2025 | Detroit City FC at New Mexico United | 9:00 p.m. |
| September 12, 2025 | Orange County SC at Lexington Sporting Club | 7:00 p.m. |
| September 12, 2025 | El Paso Locomotive FC at North Carolina FC | 7:00 p.m. |
| September 13, 2025 | Indy Eleven at Rhode Island FC | 4:00 p.m. |
| September 13, 2025 | San Antonio FC at Loudoun United FC | 6:00 p.m. |
| September 13, 2025 | Louisville City FC at Pittsburgh Riverhounds SC | 7:00 p.m. |
| September 13, 2025 | Oakland Roots at Charleston Battery | 7:30 p.m. |
| September 13, 2025 | Colorado Springs Switchbacks FC at Tampa Bay Rowdies | 7:30 p.m. |
| September 13, 2025 | FC Tulsa at New Mexico United | 9:00 p.m. |
| September 13, 2025 | Hartford Athletic at Monterey Bay FC | 10:00 p.m. |
| September 13, 2025 | Phoenix Rising FC at Sacramento Republic FC | 10:00 p.m. |
| September 13, 2025 | Miami FC at Las Vegas Lights FC | 10:30 p.m. |
| September 17, 2025 | Tampa Bay Rowdies at Birmingham Legion FC | 8:00 p.m. |
| September 20, 2025 | Lexington Sporting Club at Detroit City FC | 7:00 p.m. |
| September 20, 2025 | Pittsburgh Riverhounds SC at Hartford Athletic | 7:00 p.m. |
| September 20, 2025 | Rhode Island FC at Miami FC | 7:00 p.m. |
| September 20, 2025 | Las Vegas Lights FC at Louisville City FC | 7:30 p.m. |
| September 20, 2025 | North Carolina FC at Tampa Bay Rowdies | 7:30 p.m. |
| September 20, 2025 | Sacramento Republic FC at Colorado Springs Switchbacks FC | 8:00 p.m. |
| September 20, 2025 | Orange County SC at San Antonio FC | 8:30 p.m. |
| September 20, 2025 | Charleston Battery at El Paso Locomotive FC | 9:00 p.m. |
| September 20, 2025 | New Mexico United at Monterey Bay FC | 10:00 p.m. |
| September 20, 2025 | FC Tulsa at Oakland Roots | 10:00 p.m. |
| September 20, 2025 | Loudoun United FC at Phoenix Rising FC | 10:00 p.m. |
| September 21, 2025 | Birmingham Legion FC at Indy Eleven | 5:00 p.m. |
| September 24, 2025 | New Mexico United at Colorado Springs Switchbacks FC | 9:00 p.m. |
| September 26, 2025 | Miami FC at North Carolina FC | 7:00 p.m. |
| September 27, 2025 | Louisville City FC at Detroit City FC | 7:00 p.m. |
| September 27, 2025 | FC Tulsa at Indy Eleven | 7:00 p.m. |
| September 27, 2025 | Las Vegas Lights FC at Pittsburgh Riverhounds SC | 7:00 p.m. |
| September 27, 2025 | Hartford Athletic at Colorado Springs Switchbacks FC | 8:00 p.m. |
| September 27, 2025 | Birmingham Legion FC at San Antonio FC | 8:30 p.m. |
| September 27, 2025 | Rhode Island FC at El Paso Locomotive FC | 9:00 p.m. |
| September 27, 2025 | Sacramento Republic FC at Monterey Bay FC | 10:00 p.m. |
| September 27, 2025 | Charleston Battery at Orange County SC | 10:00 p.m. |
| September 27, 2025 | Oakland Roots at Phoenix Rising FC | 10:00 p.m. |
| September 28, 2025 | Tampa Bay Rowdies at Loudoun United FC | 5:00 p.m. |
| September 28, 2025 | Lexington Sporting Club at New Mexico United | 6:00 p.m. |
| October 1, 2025 | Oakland Roots at El Paso Locomotive FC | 2:00 p.m. |
| October 1, 2025 | Orange County SC at Sacramento Republic FC | 10:00 p.m. |
| October 4, 2025 | North Carolina FC at Detroit City FC | 4:00 p.m. |
| October 4, 2025 | Birmingham Legion FC at Loudoun United FC | 5:00 p.m. |
| October 4, 2025 | Pittsburgh Riverhounds SC at Miami FC | 7:00 p.m. |
| October 4, 2025 | Indy Eleven at Louisville City FC | 7:30 p.m. |
| October 4, 2025 | Monterey Bay FC at Tampa Bay Rowdies | 7:30 p.m. |
| October 4, 2025 | San Antonio FC at Colorado Springs Switchbacks FC | 8:00 p.m. |
| October 4, 2025 | Lexington Sporting Club at FC Tulsa | 8:00 p.m. |
| October 4, 2025 | Hartford Athletic at Oakland Roots | 10:00 p.m. |
| October 4, 2025 | El Paso Locomotive FC at Orange County SC | 10:00 p.m. |
| October 4, 2025 | New Mexico United at Phoenix Rising FC | 10:00 p.m. |
| October 5, 2025 | Las Vegas Lights FC at Rhode Island FC | 4:00 p.m. |
| October 5, 2025 | Charleston Battery at Sacramento Republic FC | 7:00 p.m. |
| October 10, 2025 | Phoenix Rising FC at North Carolina FC | 7:00 p.m. |
| October 11, 2025 | Loudoun United FC at Detroit City FC | 4:00 p.m. |
| October 11, 2025 | Tampa Bay Rowdies at Rhode Island FC | 4:00 p.m. |
| October 11, 2025 | Sacramento Republic FC at Hartford Athletic | 7:00 p.m. |
| October 11, 2025 | El Paso Locomotive FC at Lexington Sporting Club | 7:00 p.m. |
| October 11, 2025 | Indy Eleven at Pittsburgh Riverhounds SC | 7:00 p.m. |
| October 11, 2025 | Colorado Springs Switchbacks FC at Charleston Battery | 7:30 p.m. |
| October 11, 2025 | Miami FC at Louisville City FC | 7:30 p.m. |
| October 11, 2025 | San Antonio FC at FC Tulsa | 8:00 p.m. |
| October 11, 2025 | Orange County SC at New Mexico United | 9:00 p.m. |
| October 11, 2025 | Oakland Roots at Las Vegas Lights FC | 10:30 p.m. |
| October 16, 2025 | North Carolina FC at Birmingham Legion FC | 8:00 p.m. |
| October 17, 2025 | Sacramento Republic FC at Lexington Sporting Club | 7:00 p.m. |
| October 18, 2025 | Loudoun United FC at Indy Eleven | 7:00 p.m. |
| October 18, 2025 | Rhode Island FC at North Carolina FC | 7:00 p.m. |
| October 18, 2025 | Detroit City FC at Charleston Battery | 7:30 p.m. |
| October 18, 2025 | Hartford Athletic at Tampa Bay Rowdies | 7:30 p.m. |
| October 18, 2025 | Las Vegas Lights FC at Colorado Springs Switchbacks FC | 8:00 p.m. |
| October 18, 2025 | FC Tulsa at El Paso Locomotive FC | 9:00 p.m. |
| October 18, 2025 | Pittsburgh Riverhounds SC at Monterey Bay FC | 10:00 p.m. |
| October 18, 2025 | Louisville City FC at Orange County SC | 10:00 p.m. |
| October 18, 2025 | San Antonio FC at Phoenix Rising FC | 10:00 p.m. |
| October 19, 2025 | Miami FC at Birmingham Legion FC | 5:00 p.m. |
| October 19, 2025 | Oakland Roots at New Mexico United | 5:00 p.m. |
| October 24, 2025 | Rhode Island FC at New Mexico United | 9:00 p.m. |
| October 25, 2025 | Birmingham Legion FC at Charleston Battery | 5:00 p.m. |
| October 25, 2025 | North Carolina FC at Loudoun United FC | 5:00 p.m. |
| October 25, 2025 | Phoenix Rising FC at Pittsburgh Riverhounds SC | 7:00 p.m. |
| October 25, 2025 | Hartford Athletic at Louisville City FC | 7:30 p.m. |
| October 25, 2025 | Detroit City FC at Tampa Bay Rowdies | 7:30 p.m. |
| October 25, 2025 | Colorado Springs Switchbacks FC at FC Tulsa | 8:00 p.m. |
| October 25, 2025 | El Paso Locomotive FC at San Antonio FC | 8:30 p.m. |
| October 25, 2025 | Las Vegas Lights FC at Monterey Bay FC | 10:00 p.m. |
| October 25, 2025 | Lexington Sporting Club at Oakland Roots | 10:00 p.m. |
| October 25, 2025 | Indy Eleven at Orange County SC | 10:00 p.m. |
| October 25, 2025 | Miami FC at Sacramento Republic FC | 10:00 p.m. |
United Soccer League Championship Schedule
