| | | |
| February 21, 2026 | | Columbus Crew SC at Portland Timbers | 11:30 p.m. |
| February 28, 2026 | | Portland Timbers at Colorado Rapids | 5:30 p.m. |
| March 7, 2026 | | Vancouver Whitecaps FC at Portland Timbers | 11:30 p.m. |
| March 14, 2026 | | Portland Timbers at Houston Dynamo FC | 8:30 p.m. |
| March 22, 2026 | | LA Galaxy at Portland Timbers | 4:45 p.m. |
| April 4, 2026 | | Portland Timbers at Vancouver Whitecaps FC | 10:30 p.m. |
| April 11, 2026 | | Los Angeles FC at Portland Timbers | 4:45 p.m. |
| April 18, 2026 | | Portland Timbers at Minnesota United FC | 8:30 p.m. |
| April 25, 2026 | | Portland Timbers at San Diego FC | 9:30 p.m. |
| May 2, 2026 | | Portland Timbers at Real Salt Lake | 4:45 p.m. |
| May 9, 2026 | | Sporting Kansas City at Portland Timbers | 10:30 p.m. |
| May 13, 2026 | | Portland Timbers at Club de Foot Montreal | 7:30 p.m. |
| May 17, 2026 | | Portland Timbers at Inter Miami CF | 6:00 p.m. |
| May 23, 2026 | | San Jose Earthquakes at Portland Timbers | 9:30 p.m. |
| July 16, 2026 | | Portland Timbers at Seattle Sounders FC | 10:30 p.m. |
| July 22, 2026 | | FC Dallas at Portland Timbers | 10:30 p.m. |
| July 25, 2026 | | Real Salt Lake at Portland Timbers | 10:30 p.m. |
| August 1, 2026 | | Seattle Sounders FC at Portland Timbers | 10:45 p.m. |
| August 16, 2026 | | Portland Timbers at Chicago Fire FC | 6:30 p.m. |
| August 19, 2026 | | San Diego FC at Portland Timbers | 10:30 p.m. |
| August 22, 2026 | | Portland Timbers at Los Angeles FC | 10:30 p.m. |
| August 29, 2026 | | Austin FC at Portland Timbers | 10:30 p.m. |
| September 5, 2026 | | Minnesota United FC at Portland Timbers | 10:30 p.m. |
| September 9, 2026 | | St. Louis City SC at Portland Timbers | 10:30 p.m. |
| September 12, 2026 | | Portland Timbers at FC Dallas | 8:30 p.m. |
| September 19, 2026 | | Atlanta United FC at Portland Timbers | 10:30 p.m. |
| September 26, 2026 | | Portland Timbers at San Jose Earthquakes | 10:30 p.m. |
| October 10, 2026 | | Portland Timbers at Sporting Kansas City | 8:30 p.m. |
| October 14, 2026 | | Portland Timbers at LA Galaxy | 10:30 p.m. |
| October 17, 2026 | | Colorado Rapids at Portland Timbers | 10:30 p.m. |
| October 24, 2026 | | Charlotte FC at Portland Timbers | 10:30 p.m. |
| October 28, 2026 | | Portland Timbers at St. Louis City SC | 8:30 p.m. |
| November 1, 2026 | | Houston Dynamo FC at Portland Timbers | 10:15 p.m. |
| November 7, 2026 | | Portland Timbers at Austin FC | 8:00 p.m. |
Portland Timbers Schedule
