| | | |
| March 7, 2025 | Richmond Kickers 4 at South Georgia Tormenta FC 2 | Final |
| March 8, 2025 | Westchester SC 1 at Greenville Triumph SC 1 | Final |
| March 8, 2025 | Chattanooga Red Wolves SC 1 at FC Naples 1 | Final |
| March 12, 2025 | Union Omaha 0 at Greenville Triumph SC 3 | Final |
| March 15, 2025 | Richmond Kickers 0 at Charlotte Independence 1 | Final |
| March 15, 2025 | Forward Madison FC 0 at FC Naples 2 | Final |
| March 15, 2025 | AV Alta FC 0 at South Georgia Tormenta FC 2 | Final |
| March 16, 2025 | One Knoxville SC 2 at Spokane Velocity FC 2 | Final |
| March 22, 2025 | AV Alta FC 1 at Richmond Kickers 3 | Final |
| March 22, 2025 | FC Naples 1 at Spokane Velocity FC 0 | Final |
| March 22, 2025 | One Knoxville SC 2 at Texoma FC 0 | Final |
| March 28, 2025 | Chattanooga Red Wolves SC 0 at Charlotte Independence 0 | Final |
| March 29, 2025 | Spokane Velocity FC 4 at Greenville Triumph SC 0 | Final |
| March 29, 2025 | Forward Madison FC 2 at Richmond Kickers 1 | Final |
| March 29, 2025 | Portland Hearts of Pine 0 at FC Naples 0 | Final |
| March 29, 2025 | Union Omaha 3 at South Georgia Tormenta FC 1 | Final |
| March 29, 2025 | Westchester SC 3 at Texoma FC 1 | Final |
| April 5, 2025 | South Georgia Tormenta FC 2 at Chattanooga Red Wolves SC 2 | Final |
| April 5, 2025 | Charlotte Independence 0 at Greenville Triumph SC 1 | Final |
| April 5, 2025 | FC Naples 3 at Texoma FC 0 | Final |
| April 5, 2025 | Portland Hearts of Pine 0 at Spokane Velocity FC 0 | Final |
| April 5, 2025 | Westchester SC 0 at AV Alta FC 2 | Final |
| April 9, 2025 | One Knoxville SC 1 at Greenville Triumph SC 0 | Final |
| April 9, 2025 | Union Omaha 0 at Richmond Kickers 1 | Final |
| April 11, 2025 | Forward Madison FC 1 at Charlotte Independence 1 | Final |
| April 12, 2025 | Richmond Kickers 1 at FC Naples 2 | Final |
| April 12, 2025 | Portland Hearts of Pine 1 at South Georgia Tormenta FC 2 | Final |
| April 12, 2025 | Chattanooga Red Wolves SC 2 at AV Alta FC 3 | Final |
| April 13, 2025 | Texoma FC 1 at Spokane Velocity FC 4 | Final |
| April 19, 2025 | Westchester SC 4 at Richmond Kickers 4 | Final |
| April 19, 2025 | Greenville Triumph SC 0 at Chattanooga Red Wolves SC 1 | Final |
| April 19, 2025 | One Knoxville SC 1 at FC Naples 0 | Final |
| April 19, 2025 | Texoma FC 1 at Forward Madison FC 1 | Final |
| April 19, 2025 | Spokane Velocity FC 2 at AV Alta FC 1 | Final |
| April 20, 2025 | South Georgia Tormenta FC 2 at Charlotte Independence 3 | Final |
| April 25, 2025 | Charlotte Independence 2 at North Carolina FC 1 (Jagermeister Cup) | Final |
| April 26, 2025 | Portland Hearts of Pine 0 at Hartford Athletic 2 (Jagermeister Cup) | Final |
| April 26, 2025 | Charleston Battery 0 at FC Naples 1 (Jagermeister Cup) | Final |
| April 26, 2025 | Indy Eleven 4 at Forward Madison FC 0 (Jagermeister Cup) | Final |
| April 26, 2025 | FC Tulsa 2 at One Knoxville SC 2 (Jagermeister Cup) | Final |
| April 26, 2025 | Richmond Kickers 1 at Louisville City FC 4 (Jagermeister Cup) | Final |
| April 26, 2025 | Greenville Triumph SC 1 at South Georgia Tormenta FC 2 (Jagermeister Cup) | Final |
| April 26, 2025 | El Paso Locomotive FC 0 at Texoma FC 0 (Jagermeister Cup) | Final |
| April 26, 2025 | Union Omaha 0 at New Mexico United 2 (Jagermeister Cup) | Final |
| April 26, 2025 | AV Alta FC 0 at Sacramento Republic FC 1 (Jagermeister Cup) | Final |
| April 27, 2025 | Rhode Island FC 4 at Westchester SC 1 (Jagermeister Cup) | Final |
| April 27, 2025 | Chattanooga Red Wolves SC 1 at Birmingham Legion FC 3 (Jagermeister Cup) | Final |
| April 27, 2025 | Oakland Roots 1 at Spokane Velocity FC 2 (Jagermeister Cup) | Final |
| April 30, 2025 | AV Alta FC 1 at Las Vegas Lights FC 2 (Jagermeister Cup) | Final |
| May 2, 2025 | Greenville Triumph SC 3 at Richmond Kickers 3 | Final |
| May 3, 2025 | Union Omaha 0 at Forward Madison FC 0 | Final |
| May 3, 2025 | Charlotte Independence 4 at Texoma FC 3 | Final |
| May 4, 2025 | One Knoxville SC 1 at Portland Hearts of Pine 1 | Final |
| May 4, 2025 | Westchester SC 1 at Spokane Velocity FC 3 | Final |
| May 9, 2025 | Forward Madison FC 1 at One Knoxville SC 1 | Final |
| May 10, 2025 | Charlotte Independence 3 at Westchester SC 2 | Final |
| May 10, 2025 | Richmond Kickers 0 at Chattanooga Red Wolves SC 0 | Final |
| May 10, 2025 | Spokane Velocity FC 1 at South Georgia Tormenta FC 0 | Final |
| May 10, 2025 | Portland Hearts of Pine 2 at Union Omaha 2 | Final |
| May 10, 2025 | Texoma FC 0 at AV Alta FC 0 | Final |
| May 14, 2025 | FC Naples 1 at Chattanooga Red Wolves SC 3 | Final |
| May 16, 2025 | One Knoxville SC 1 at Charlotte Independence 3 | Final |
| May 17, 2025 | Forward Madison FC 1 at Westchester SC 1 | Final |
| May 17, 2025 | FC Naples 1 at Portland Hearts of Pine 2 | Final |
| May 17, 2025 | AV Alta FC 2 at Greenville Triumph SC 2 | Final |
| May 17, 2025 | Union Omaha 1 at Texoma FC 2 | Final |
| May 18, 2025 | Richmond Kickers 0 at Spokane Velocity FC 1 | Final |
| May 24, 2025 | Portland Hearts of Pine 1 at Forward Madison FC 1 | Final |
| May 24, 2025 | Indy Eleven 1 at One Knoxville SC 0 (Jagermeister Cup) | Final |
| May 24, 2025 | Chattanooga Red Wolves SC 2 at South Georgia Tormenta FC 1 | Final |
| May 24, 2025 | Charlotte Independence 1 at AV Alta FC 2 | Final |
| May 25, 2025 | Richmond Kickers 2 at Westchester SC 2 | Final |
| May 25, 2025 | Greenville Triumph SC 0 at Texoma FC 1 | Final |
| May 25, 2025 | Union Omaha 1 at FC Naples 3 | Final |
| May 28, 2025 | Spokane Velocity FC 0 at Monterey Bay FC 1 (Jagermeister Cup) | Final |
| May 31, 2025 | Hartford Athletic 3 at Westchester SC 2 (Jagermeister Cup) | Final |
| May 31, 2025 | Greenville Triumph SC 1 at Charleston Battery 0 (Jagermeister Cup) | Final |
| May 31, 2025 | Detroit City FC 2 at Portland Hearts of Pine 4 (Jagermeister Cup) | Final |
| May 31, 2025 | FC Naples 2 at Miami FC 3 (Jagermeister Cup) | Final |
| May 31, 2025 | Lexington Sporting Club 2 at Charlotte Independence 2 (Jagermeister Cup) | Final |
| May 31, 2025 | Forward Madison FC 1 at Chattanooga Red Wolves SC 1 | Final |
| May 31, 2025 | North Carolina FC 1 at Richmond Kickers 0 (Jagermeister Cup) | Final |
| May 31, 2025 | South Georgia Tormenta FC 1 at Tampa Bay Rowdies 2 (Jagermeister Cup) | Final |
| May 31, 2025 | Oakland Roots 2 at AV Alta FC 2 (Jagermeister Cup) | Final |
| June 7, 2025 | Portland Hearts of Pine 1 at Chattanooga Red Wolves SC 2 | Final |
| June 7, 2025 | FC Naples 1 at Greenville Triumph SC 1 | Final |
| June 7, 2025 | Texoma FC 2 at Richmond Kickers 1 | Final |
| June 7, 2025 | One Knoxville SC 1 at Westchester SC 1 | Final |
| June 7, 2025 | Charlotte Independence 2 at South Georgia Tormenta FC 0 | Final |
| June 7, 2025 | Union Omaha 1 at Forward Madison FC 0 | Final |
| June 7, 2025 | Spokane Velocity FC 0 at AV Alta FC 0 | Final |
| June 11, 2025 | Charlotte Independence 1 at Spokane Velocity FC 1 | Final |
| June 12, 2025 | Greenville Triumph SC 0 at Union Omaha 1 | Final |
| June 13, 2025 | Richmond Kickers 1 at One Knoxville SC 1 | Susp. |
| June 14, 2025 | Chattanooga Red Wolves SC 2 at FC Naples 2 | Final |
| June 14, 2025 | South Georgia Tormenta FC 2 at Texoma FC 2 | Final |
| June 14, 2025 | Forward Madison FC 1 at Spokane Velocity FC 2 | Final |
| June 15, 2025 | Union Omaha 1 at Portland Hearts of Pine 3 | Final |
| June 15, 2025 | Greenville Triumph SC 0 at Charlotte Independence 1 | Final |
| June 15, 2025 | AV Alta FC 5 at Westchester SC 2 | Final |
| June 18, 2025 | Westchester SC 2 at Forward Madison FC 1 | Final |
| June 21, 2025 | Chattanooga Red Wolves SC 1 at Greenville Triumph SC 3 | Final |
| June 21, 2025 | South Georgia Tormenta FC 0 at One Knoxville SC 3 | Final |
| June 21, 2025 | Spokane Velocity FC 1 at Richmond Kickers 0 | Final |
| June 21, 2025 | Charlotte Independence 2 at Texoma FC 3 | Final |
| June 21, 2025 | Portland Hearts of Pine 1 at AV Alta FC 1 | Final |
| June 25, 2025 | FC Naples 1 at South Georgia Tormenta FC 2 | Final |
| June 25, 2025 | Richmond Kickers 4 at Union Omaha 3 | Final |
| June 27, 2025 | Portland Hearts of Pine 1 at Rhode Island FC 4 (Jagermeister Cup) | Final |
| June 28, 2025 | Charlotte Independence 1 at Loudoun United FC 1 (Jagermeister Cup) | Final |
| June 28, 2025 | Westchester SC 0 at Pittsburgh Riverhounds SC 1 (Jagermeister Cup) | Final |
| June 28, 2025 | One Knoxville SC 0 at Forward Madison FC 1 (Jagermeister Cup) | Final |
| June 28, 2025 | Miami FC 0 at Greenville Triumph SC 2 (Jagermeister Cup) | Final |
| June 28, 2025 | Lexington Sporting Club 3 at Richmond Kickers 0 (Jagermeister Cup) | Final |
| June 28, 2025 | Charleston Battery 3 at South Georgia Tormenta FC 3 (Jagermeister Cup) | Final |
| June 28, 2025 | Chattanooga Red Wolves SC 1 at FC Tulsa 4 (Jagermeister Cup) | Final |
| June 28, 2025 | Phoenix Rising FC 5 at Texoma FC 4 (Jagermeister Cup) | Final |
| June 28, 2025 | Union Omaha 0 at San Antonio FC 1 (Jagermeister Cup) | Final |
| June 28, 2025 | Spokane Velocity FC 0 at Las Vegas Lights FC 2 (Jagermeister Cup) | Final |
| June 28, 2025 | FC Naples 1 at AV Alta FC 4 | Final |
| July 2, 2025 | AV Alta FC 2 at Portland Hearts of Pine 0 | Final |
| July 2, 2025 | Greenville Triumph SC 3 at Westchester SC 0 | Final |
| July 2, 2025 | Texoma FC 1 at Spokane Velocity FC 1 | Final |
| July 4, 2025 | Tampa Bay Rowdies 2 at FC Naples 0 (Jagermeister Cup) | Final |
| July 5, 2025 | One Knoxville SC 0 at Chattanooga Red Wolves SC 1 | Final |
| July 5, 2025 | Forward Madison FC 0 at Texoma FC 2 | Final |
| July 5, 2025 | Union Omaha 1 at AV Alta FC 2 | Final |
| July 6, 2025 | South Georgia Tormenta FC 1 at Portland Hearts of Pine 1 | Final |
| July 12, 2025 | Union Omaha 2 at Charlotte Independence 1 | Final |
| July 12, 2025 | Chattanooga Red Wolves SC 2 at Richmond Kickers 0 | Final |
| July 12, 2025 | One Knoxville SC 2 at South Georgia Tormenta FC 1 | Final |
| July 12, 2025 | Westchester SC 1 at FC Naples 2 | Final |
| July 12, 2025 | Greenville Triumph SC 1 at Forward Madison FC 3 | Final |
| July 12, 2025 | Portland Hearts of Pine 1 at Texoma FC 0 | Final |
| July 16, 2025 | Greenville Triumph SC 1 at Portland Hearts of Pine 3 | Final |
| July 16, 2025 | Texoma FC 1 at Chattanooga Red Wolves SC 1 | Final |
| July 16, 2025 | AV Alta FC 1 at One Knoxville SC 3 | Final |
| July 16, 2025 | Spokane Velocity FC 3 at Westchester SC 2 | Final |
| July 16, 2025 | Charlotte Independence 1 at Forward Madison FC 1 | Final |
| July 18, 2025 | South Georgia Tormenta FC 2 at Union Omaha 1 | Final |
| July 19, 2025 | Portland Hearts of Pine 1 at Charlotte Independence 1 | Final |
| July 19, 2025 | Spokane Velocity FC 0 at Chattanooga Red Wolves SC 3 | Final |
| July 19, 2025 | Westchester SC 1 at One Knoxville SC 1 | Final |
| July 19, 2025 | FC Naples 1 at AV Alta FC 1 | Final |
| July 20, 2025 | Richmond Kickers 0 at Greenville Triumph SC 2 | Final |
| July 23, 2025 | South Georgia Tormenta FC 0 at Forward Madison FC 1 | Final |
| July 23, 2025 | Texoma FC 1 at Union Omaha 3 (Jagermeister Cup) | Final |
| July 25, 2025 | Pittsburgh Riverhounds SC 2 at Portland Hearts of Pine 2 (Jagermeister Cup) | Final |
| July 26, 2025 | Westchester SC 0 at Detroit City FC 3 (Jagermeister Cup) | Final |
| July 26, 2025 | South Georgia Tormenta FC 2 at Miami FC 1 (Jagermeister Cup) | Final |
| July 26, 2025 | Richmond Kickers 0 at Charlotte Independence 3 (Jagermeister Cup) | Final |
| July 26, 2025 | One Knoxville SC 0 at Chattanooga Red Wolves SC 1 (Jagermeister Cup) | Final |
| July 26, 2025 | FC Naples 1 at Greenville Triumph SC 2 (Jagermeister Cup) | Final |
| July 26, 2025 | Forward Madison FC 1 at Birmingham Legion FC 2 (Jagermeister Cup) | Final |
| July 26, 2025 | El Paso Locomotive FC 1 at Union Omaha 0 (Jagermeister Cup) | Final |
| July 26, 2025 | Texoma FC 0 at Colorado Springs Switchbacks FC 4 (Jagermeister Cup) | Final |
| July 26, 2025 | Sacramento Republic FC 1 at Spokane Velocity FC 0 (Jagermeister Cup) | Final |
| July 26, 2025 | Monterey Bay FC 1 at AV Alta FC 2 (Jagermeister Cup) | Final |
| July 30, 2025 | Charlotte Independence 2 at One Knoxville SC 2 | Final |
| August 1, 2025 | Chattanooga Red Wolves SC 3 at Westchester SC 1 | Final |
| August 2, 2025 | AV Alta FC 0 at Forward Madison FC 0 | Final |
| August 2, 2025 | Texoma FC 3 at Charlotte Independence 3 | Final |
| August 2, 2025 | Portland Hearts of Pine 0 at One Knoxville SC 1 | Final |
| August 2, 2025 | FC Naples 2 at Richmond Kickers 1 | Final |
| August 2, 2025 | Greenville Triumph SC 2 at South Georgia Tormenta FC 2 | Final |
| August 2, 2025 | Union Omaha 1 at Spokane Velocity FC 2 | Final |
| August 6, 2025 | Forward Madison FC 1 at Chattanooga Red Wolves SC 2 | Final |
| August 6, 2025 | South Georgia Tormenta FC 1 at FC Naples 2 | Final |
| August 6, 2025 | Westchester SC 1 at Union Omaha 2 | Final |
| August 9, 2025 | Richmond Kickers 0 at Portland Hearts of Pine 0 | Final |
| August 9, 2025 | Greenville Triumph SC 5 at Charlotte Independence 4 | Final |
| August 9, 2025 | Texoma FC 1 at FC Naples 2 | Final |
| August 9, 2025 | One Knoxville SC 2 at Forward Madison FC 2 | Final |
| August 9, 2025 | Chattanooga Red Wolves SC 2 at Union Omaha 2 | Final |
| August 9, 2025 | AV Alta FC 0 at Spokane Velocity FC 2 | Final |
| August 10, 2025 | South Georgia Tormenta FC 3 at Westchester SC 3 | Final |
| August 15, 2025 | Westchester SC 0 at Charlotte Independence 1 | Final |
| August 16, 2025 | Union Omaha 0 at One Knoxville SC 1 | Final |
| August 16, 2025 | South Georgia Tormenta FC 3 at Richmond Kickers 2 | Final |
| August 16, 2025 | FC Naples 0 at Forward Madison FC 0 | Final |
| August 16, 2025 | Chattanooga Red Wolves SC 1 at Texoma FC 0 | Final |
| August 16, 2025 | Greenville Triumph SC 1 at AV Alta FC 1 | Final |
| August 17, 2025 | Spokane Velocity FC at Portland Hearts of Pine | Ppd. |
| August 20, 2025 | Greenville Triumph SC 1 at Indy Eleven 1 (Jagermeister Cup) | Final (PK 6-5) |
| August 20, 2025 | AV Alta FC 3 at Texoma FC 3 | Final |
| August 20, 2025 | Charlotte Independence 1 at Union Omaha 4 | Final |
| August 21, 2025 | Spokane Velocity FC 1 at Forward Madison FC 0 | Final |
| August 23, 2025 | South Georgia Tormenta FC 0 at Chattanooga Red Wolves SC 2 | Final |
| August 23, 2025 | Texoma FC 1 at Greenville Triumph SC 0 | Final |
| August 23, 2025 | One Knoxville SC 0 at Richmond Kickers 1 | Final |
| August 23, 2025 | AV Alta FC 0 at Union Omaha 2 | Final |
| August 24, 2025 | Portland Hearts of Pine 3 at Westchester SC 2 | Final |
| August 27, 2025 | FC Naples 0 at One Knoxville SC 0 | Final |
| August 27, 2025 | Texoma FC 0 at Forward Madison FC 3 | Final |
| August 30, 2025 | Spokane Velocity FC 0 at One Knoxville SC 1 | Final |
| August 30, 2025 | Charlotte Independence 2 at Portland Hearts of Pine 4 | Final |
| August 30, 2025 | AV Alta FC 0 at Chattanooga Red Wolves SC 0 | Final |
| August 30, 2025 | Westchester SC 2 at FC Naples 2 | Final |
| August 30, 2025 | Forward Madison FC 0 at South Georgia Tormenta FC 4 | Final |
| September 3, 2025 | Portland Hearts of Pine 3 at Greenville Triumph SC 2 | Final |
| September 3, 2025 | Richmond Kickers 2 at Westchester SC 0 | Final |
| September 6, 2025 | Texoma FC 0 at Union Omaha 5 | Final |
| September 6, 2025 | Charlotte Independence 0 at Chattanooga Red Wolves SC 1 | Final |
| September 6, 2025 | Greenville Triumph SC 1 at FC Naples 2 | Final |
| September 6, 2025 | One Knoxville SC 1 at South Georgia Tormenta FC 2 | Final |
| September 6, 2025 | Forward Madison FC 3 at AV Alta FC 3 | Final |
| September 7, 2025 | Westchester SC 1 at Spokane Velocity FC 2 | Final |
| September 10, 2025 | Greenville Triumph SC 1 at Hartford Athletic 3 (Jagermeister Cup) | Final |
| September 12, 2025 | FC Naples 1 at Charlotte Independence 0 | Final |
| September 13, 2025 | Chattanooga Red Wolves SC 1 at Portland Hearts of Pine 1 | Final |
| September 13, 2025 | Richmond Kickers 0 at Forward Madison FC 1 | Final |
| September 13, 2025 | South Georgia Tormenta FC 2 at Greenville Triumph SC 1 | Final |
| September 13, 2025 | Union Omaha 2 at Westchester SC 1 | Final |
| September 13, 2025 | Spokane Velocity FC 3 at Texoma FC 3 | Final |
| September 13, 2025 | One Knoxville SC 2 at AV Alta FC 1 | Final |
| September 17, 2025 | Portland Hearts of Pine 5 at Richmond Kickers 2 | Final |
| September 17, 2025 | Spokane Velocity FC 2 at Union Omaha 2 | Final |
| September 20, 2025 | Charlotte Independence 3 at Richmond Kickers 2 | Final |
| September 20, 2025 | Forward Madison FC 0 at Greenville Triumph SC 3 | Final |
| September 20, 2025 | South Georgia Tormenta FC 3 at AV Alta FC 0 | Final |
| September 21, 2025 | FC Naples 0 at Portland Hearts of Pine 1 | Final |
| September 21, 2025 | One Knoxville SC 2 at Union Omaha 2 | Final |
| September 21, 2025 | Chattanooga Red Wolves SC 2 at Spokane Velocity FC 1 | Final |
| September 21, 2025 | Texoma FC 1 at Westchester SC 2 | Final |
| September 26, 2025 | Charlotte Independence 0 at One Knoxville SC 1 | Final |
| September 27, 2025 | Texoma FC 0 at Portland Hearts of Pine 1 | Final |
| September 27, 2025 | Union Omaha 3 at Chattanooga Red Wolves SC 0 | Final |
| September 27, 2025 | AV Alta FC 0 at FC Naples 4 | Final |
| September 27, 2025 | Richmond Kickers 2 at South Georgia Tormenta FC 4 | Final |
| September 27, 2025 | Greenville Triumph SC 1 at Spokane Velocity FC 0 | Final |
| September 28, 2025 | Forward Madison FC 1 at Westchester SC 0 | Final |
| October 1, 2025 | Portland Hearts of Pine at Union Omaha | 1:00 p.m. |
| October 1, 2025 | Chattanooga Red Wolves SC at One Knoxville SC | 6:30 p.m. |
| October 3, 2025 | Spokane Velocity FC at Charlotte Independence | 7:00 p.m. |
| October 3, 2025 | Westchester SC at South Georgia Tormenta FC | 7:00 p.m. |
| October 4, 2025 | Forward Madison FC at Portland Hearts of Pine | 5:00 p.m. |
| October 4, 2025 | One Knoxville SC at Richmond Kickers | 6:00 p.m. |
| October 4, 2025 | Greenville Triumph SC at Chattanooga Red Wolves SC | 7:00 p.m. |
| October 4, 2025 | AV Alta FC at Texoma FC | 8:00 p.m. |
| October 5, 2025 | FC Naples at Union Omaha | TBD |
| October 10, 2025 | Portland Hearts of Pine at One Knoxville SC | 6:30 p.m. |
| October 10, 2025 | AV Alta FC at Charlotte Independence | 7:00 p.m. |
| October 11, 2025 | Chattanooga Red Wolves SC at Forward Madison FC | 6:00 p.m. |
| October 11, 2025 | Union Omaha at Greenville Triumph SC | 7:00 p.m. |
| October 11, 2025 | Richmond Kickers at Texoma FC | 8:00 p.m. |
| October 11, 2025 | South Georgia Tormenta FC at Spokane Velocity FC | 9:00 p.m. |
| October 12, 2025 | FC Naples at Westchester SC | 2:00 p.m. |
| October 17, 2025 | Chattanooga Red Wolves SC at Charlotte Independence | 7:00 p.m. |
| October 18, 2025 | Westchester SC at Portland Hearts of Pine | 5:00 p.m. |
| October 18, 2025 | Spokane Velocity FC at FC Naples | 7:00 p.m. |
| October 18, 2025 | South Georgia Tormenta FC at Greenville Triumph SC | 7:00 p.m. |
| October 18, 2025 | Forward Madison FC at Union Omaha | 7:00 p.m. |
| October 18, 2025 | Richmond Kickers at AV Alta FC | 10:30 p.m. |
| October 19, 2025 | Texoma FC at One Knoxville SC | 3:00 p.m. |
| October 21, 2025 | Spokane Velocity FC at Portland Hearts of Pine | 6:30 p.m. |
| October 25, 2025 | Spokane Velocity FC at Union Omaha | TBD |
| October 25, 2025 | AV Alta FC at Portland Hearts of Pine | 5:00 p.m. |
| October 25, 2025 | Forward Madison FC at Richmond Kickers | 6:00 p.m. |
| October 25, 2025 | Westchester SC at Chattanooga Red Wolves SC | 7:00 p.m. |
| October 25, 2025 | Charlotte Independence at FC Naples | 7:00 p.m. |
| October 25, 2025 | Greenville Triumph SC at One Knoxville SC | 7:00 p.m. |
| October 25, 2025 | Texoma FC at South Georgia Tormenta FC | 7:00 p.m. |
United Soccer League One Schedule
