| | | |
| February 22, 2025 | L | Sporting Kansas City 0 at Austin FC 1 | Final |
| March 1, 2025 | L | San Jose Earthquakes 2 at Sporting Kansas City 1 | Final |
| March 8, 2025 | L | Sporting Kansas City 1 at D.C. United 2 | Final |
| March 15, 2025 | T | Minnesota United FC 3 at Sporting Kansas City 3 | Final |
| March 22, 2025 | L | Los Angeles FC 2 at Sporting Kansas City 0 | Final |
| March 29, 2025 | L | Sporting Kansas City 1 at FC Dallas 2 | Final |
| April 5, 2025 | W | St. Louis City SC 0 at Sporting Kansas City 2 | Final |
| April 13, 2025 | L | Portland Timbers 4 at Sporting Kansas City 2 | Final |
| April 19, 2025 | W | Sporting Kansas City 5 at San Jose Earthquakes 3 | Final |
| April 26, 2025 | L | Sporting Kansas City 1 at FC Cincinnati 2 | Final |
| May 4, 2025 | | LA Galaxy at Sporting Kansas City | 7:00 p.m. |
| May 10, 2025 | | Sporting Kansas City at Portland Timbers | 10:30 p.m. |
| May 14, 2025 | | Sporting Kansas City at St. Louis City SC | 8:30 p.m. |
| May 17, 2025 | | Sporting Kansas City at San Diego FC | 10:30 p.m. |
| May 24, 2025 | | New England Revolution at Sporting Kansas City | 8:30 p.m. |
| May 28, 2025 | | Sporting Kansas City at Los Angeles FC | 10:30 p.m. |
| May 31, 2025 | | Sporting Kansas City at Houston Dynamo FC | 8:30 p.m. |
| June 14, 2025 | | FC Dallas at Sporting Kansas City | 8:30 p.m. |
| June 25, 2025 | | Charlotte FC at Sporting Kansas City | 8:30 p.m. |
| June 28, 2025 | | Real Salt Lake at Sporting Kansas City | 8:30 p.m. |
| July 4, 2025 | | Sporting Kansas City at Colorado Rapids | 9:30 p.m. |
| July 12, 2025 | | Seattle Sounders FC at Sporting Kansas City | 8:30 p.m. |
| July 19, 2025 | | New York City FC at Sporting Kansas City | 8:30 p.m. |
| July 26, 2025 | | Sporting Kansas City at Vancouver Whitecaps FC | 10:30 p.m. |
| August 9, 2025 | | San Diego FC at Sporting Kansas City | 8:30 p.m. |
| August 16, 2025 | | Sporting Kansas City at Orlando City SC | 7:30 p.m. |
| August 24, 2025 | | Sporting Kansas City at Seattle Sounders FC | 9:00 p.m. |
| August 30, 2025 | | Colorado Rapids at Sporting Kansas City | 8:30 p.m. |
| September 7, 2025 | | Austin FC at Sporting Kansas City | 7:00 p.m. |
| September 13, 2025 | | Sporting Kansas City at Real Salt Lake | 9:30 p.m. |
| September 20, 2025 | | Vancouver Whitecaps FC at Sporting Kansas City | 8:30 p.m. |
| September 27, 2025 | | Sporting Kansas City at LA Galaxy | 10:30 p.m. |
| October 4, 2025 | | Sporting Kansas City at Minnesota United FC | 8:30 p.m. |
| October 18, 2025 | | Houston Dynamo FC at Sporting Kansas City | 9:00 p.m. |
Sporting Kansas City Schedule
