| | | |
| February 22, 2026 | W | Colorado Rapids 0 at Seattle Sounders FC 2 | Final |
| February 28, 2026 | L | Seattle Sounders FC 1 at Real Salt Lake 2 | Final |
| March 7, 2026 | W | Seattle Sounders FC 1 at St. Louis City SC 0 | Final |
| March 15, 2026 | W | Seattle Sounders FC 1 at San Jose Earthquakes 0 | Final |
| March 22, 2026 | T | Seattle Sounders FC 0 at Minnesota United FC 0 | Final |
| April 4, 2026 | | Seattle Sounders FC at Houston Dynamo FC | 7:30 p.m. |
| April 18, 2026 | | St. Louis City SC at Seattle Sounders FC | 8:30 p.m. |
| April 25, 2026 | | FC Dallas at Seattle Sounders FC | 9:30 p.m. |
| May 2, 2026 | | Seattle Sounders FC at Sporting Kansas City | 1:30 p.m. |
| May 9, 2026 | | San Diego FC at Seattle Sounders FC | 9:30 p.m. |
| May 13, 2026 | | San Jose Earthquakes at Seattle Sounders FC | 8:30 p.m. |
| May 16, 2026 | | LA Galaxy at Seattle Sounders FC | 8:00 p.m. |
| May 24, 2026 | | Seattle Sounders FC at Los Angeles FC | 8:00 p.m. |
| July 16, 2026 | | Portland Timbers at Seattle Sounders FC | 9:30 p.m. |
| July 22, 2026 | | Seattle Sounders FC at Austin FC | 7:30 p.m. |
| July 25, 2026 | | Seattle Sounders FC at Philadelphia Union | 6:30 p.m. |
| August 1, 2026 | | Seattle Sounders FC at Portland Timbers | 9:45 p.m. |
| August 16, 2026 | | Vancouver Whitecaps FC at Seattle Sounders FC | 8:00 p.m. |
| August 19, 2026 | | Austin FC at Seattle Sounders FC | 8:30 p.m. |
| August 22, 2026 | | Seattle Sounders FC at FC Cincinnati | 6:30 p.m. |
| August 29, 2026 | | Chicago Fire FC at Seattle Sounders FC | 3:30 p.m. |
| September 5, 2026 | | Red Bull New York at Seattle Sounders FC | 7:30 p.m. |
| September 12, 2026 | | Seattle Sounders FC at LA Galaxy | 9:30 p.m. |
| September 19, 2026 | | Seattle Sounders FC at Colorado Rapids | 8:30 p.m. |
| September 23, 2026 | | Real Salt Lake at Seattle Sounders FC | 9:30 p.m. |
| September 26, 2026 | | Minnesota United FC at Seattle Sounders FC | 7:30 p.m. |
| October 1, 2026 | | Sporting Kansas City at Seattle Sounders FC | 9:30 p.m. |
| October 10, 2026 | | Seattle Sounders FC at New England Revolution | 6:30 p.m. |
| October 14, 2026 | | Seattle Sounders FC at FC Dallas | 7:30 p.m. |
| October 17, 2026 | | Club de Foot Montreal at Seattle Sounders FC | 9:30 p.m. |
| October 24, 2026 | | Seattle Sounders FC at San Diego FC | 9:30 p.m. |
| October 28, 2026 | | Houston Dynamo FC at Seattle Sounders FC | 9:30 p.m. |
| November 1, 2026 | | Seattle Sounders FC at Vancouver Whitecaps FC | 4:30 p.m. |
| November 7, 2026 | | Los Angeles FC at Seattle Sounders FC | 7:00 p.m. |
Seattle Sounders FC Schedule
