| | | |
| February 22, 2025 | L | Real Salt Lake 0 at San Jose Earthquakes 4 | Final |
| March 1, 2025 | W | Seattle Sounders FC 0 at Real Salt Lake 2 | Final |
| March 8, 2025 | L | San Diego FC 3 at Real Salt Lake 1 | Final |
| March 15, 2025 | W | Real Salt Lake 2 at Houston Dynamo FC 1 | Final |
| March 22, 2025 | L | FC Dallas 1 at Real Salt Lake 0 | Final |
| March 29, 2025 | L | Real Salt Lake 0 at Minnesota United FC 2 | Final |
| April 5, 2025 | W | LA Galaxy 0 at Real Salt Lake 2 | Final |
| April 12, 2025 | L | Real Salt Lake 1 at Nashville SC 2 | Final |
| April 19, 2025 | L | Toronto FC 1 at Real Salt Lake 0 | Final |
| April 26, 2025 | W | Real Salt Lake 3 at San Diego FC 1 | Final |
| May 3, 2025 | | Real Salt Lake at Vancouver Whitecaps FC | 9:30 p.m. |
| May 10, 2025 | | Real Salt Lake at FC Dallas | 8:30 p.m. |
| May 14, 2025 | | Portland Timbers at Real Salt Lake | 9:30 p.m. |
| May 17, 2025 | | Real Salt Lake at Colorado Rapids | 9:30 p.m. |
| May 24, 2025 | | Vancouver Whitecaps FC at Real Salt Lake | 9:30 p.m. |
| May 28, 2025 | | Real Salt Lake at Austin FC | 8:30 p.m. |
| May 31, 2025 | | Real Salt Lake at LA Galaxy | 10:30 p.m. |
| June 14, 2025 | | D.C. United at Real Salt Lake | 9:30 p.m. |
| June 25, 2025 | | Los Angeles FC at Real Salt Lake | 9:30 p.m. |
| June 28, 2025 | | Real Salt Lake at Sporting Kansas City | 8:30 p.m. |
| July 5, 2025 | | St. Louis City SC at Real Salt Lake | 9:30 p.m. |
| July 12, 2025 | | Houston Dynamo FC at Real Salt Lake | 9:30 p.m. |
| July 16, 2025 | | Real Salt Lake at Portland Timbers | 10:30 p.m. |
| July 19, 2025 | | FC Cincinnati at Real Salt Lake | 9:30 p.m. |
| July 26, 2025 | | San Jose Earthquakes at Real Salt Lake | 9:30 p.m. |
| August 10, 2025 | | Real Salt Lake at New York Red Bulls | 6:00 p.m. |
| August 16, 2025 | | Real Salt Lake at Charlotte FC | 7:30 p.m. |
| August 23, 2025 | | Minnesota United FC at Real Salt Lake | 9:30 p.m. |
| August 30, 2025 | | Real Salt Lake at Seattle Sounders FC | 10:30 p.m. |
| September 13, 2025 | | Sporting Kansas City at Real Salt Lake | 9:30 p.m. |
| September 21, 2025 | | Real Salt Lake at Los Angeles FC | 9:00 p.m. |
| September 27, 2025 | | Austin FC at Real Salt Lake | 9:30 p.m. |
| October 4, 2025 | | Colorado Rapids at Real Salt Lake | 9:30 p.m. |
| October 18, 2025 | | Real Salt Lake at St. Louis City SC | 9:00 p.m. |
Real Salt Lake Schedule
