| | | |
| September 25, 2024 | L | Windsor Spitfires 5 at Saginaw Spirit 4 | Final (OT) |
| September 27, 2024 | W | Saginaw Spirit 6 at Soo Greyhounds 4 | Final |
| September 28, 2024 | W | Sarnia Sting 1 at Saginaw Spirit 6 | Final |
| October 4, 2024 | W | Saginaw Spirit 5 at Sarnia Sting 4 | Final (SO) |
| October 5, 2024 | W | Erie Otters 3 at Saginaw Spirit 7 | Final |
| October 12, 2024 | | Kitchener Rangers at Saginaw Spirit | 7:05 p.m. |
| October 13, 2024 | | Soo Greyhounds at Saginaw Spirit | 5:30 p.m. |
| October 18, 2024 | | Saginaw Spirit at London Knights | 7:00 p.m. |
| October 19, 2024 | | Saginaw Spirit at Brampton Steelheads | 4:00 p.m. |
| October 20, 2024 | | Saginaw Spirit at Oshawa Generals | 6:05 p.m. |
| October 23, 2024 | | Saginaw Spirit at Soo Greyhounds | 7:07 p.m. |
| October 26, 2024 | | London Knights at Saginaw Spirit | 7:05 p.m. |
| October 27, 2024 | | Owen Sound Attack at Saginaw Spirit | 5:30 p.m. |
| November 2, 2024 | | Saginaw Spirit at Owen Sound Attack | 4:00 p.m. |
| November 3, 2024 | | Saginaw Spirit at Kitchener Rangers | 2:00 p.m. |
| November 7, 2024 | | Peterborough Petes at Saginaw Spirit | 7:05 p.m. |
| November 9, 2024 | | Windsor Spitfires at Saginaw Spirit | 7:05 p.m. |
| November 10, 2024 | | Flint Firebirds at Saginaw Spirit | 5:30 p.m. |
| November 13, 2024 | | Saginaw Spirit at Flint Firebirds | 7:00 p.m. |
| November 15, 2024 | | Erie Otters at Saginaw Spirit | 7:05 p.m. |
| November 16, 2024 | | Sarnia Sting at Saginaw Spirit | 7:05 p.m. |
| November 22, 2024 | | Flint Firebirds at Saginaw Spirit | 7:05 p.m. |
| November 23, 2024 | | London Knights at Saginaw Spirit | 7:05 p.m. |
| November 27, 2024 | | Saginaw Spirit at Windsor Spitfires | 7:05 p.m. |
| November 30, 2024 | | Brampton Steelheads at Saginaw Spirit | 7:05 p.m. |
| December 1, 2024 | | Saginaw Spirit at Sarnia Sting | 2:05 p.m. |
| December 4, 2024 | | Soo Greyhounds at Saginaw Spirit | 7:05 p.m. |
| December 7, 2024 | | Oshawa Generals at Saginaw Spirit | 7:05 p.m. |
| December 8, 2024 | | Saginaw Spirit at Windsor Spitfires | 4:05 p.m. |
| December 13, 2024 | | Saginaw Spirit at Guelph Storm | 7:07 p.m. |
| December 14, 2024 | | Saginaw Spirit at Erie Otters | 7:00 p.m. |
| December 18, 2024 | | Saginaw Spirit at Flint Firebirds | 7:00 p.m. |
| December 20, 2024 | | Flint Firebirds at Saginaw Spirit | 7:05 p.m. |
| December 28, 2024 | | Sarnia Sting at Saginaw Spirit | 7:05 p.m. |
| December 29, 2024 | | Niagara IceDogs at Saginaw Spirit | 5:30 p.m. |
| January 2, 2025 | | Ottawa 67's at Saginaw Spirit | 7:05 p.m. |
| January 4, 2025 | | Soo Greyhounds at Saginaw Spirit | 7:05 p.m. |
| January 9, 2025 | | Saginaw Spirit at Niagara IceDogs | 7:00 p.m. |
| January 10, 2025 | | Saginaw Spirit at Erie Otters | 7:00 p.m. |
| January 12, 2025 | | Saginaw Spirit at Kitchener Rangers | 6:00 p.m. |
| January 18, 2025 | | Guelph Storm at Saginaw Spirit | 7:05 p.m. |
| January 23, 2025 | | Saginaw Spirit at Peterborough Petes | 7:05 p.m. |
| January 24, 2025 | | Saginaw Spirit at Kingston Frontenacs | 7:00 p.m. |
| January 26, 2025 | | Saginaw Spirit at Ottawa 67's | 2:00 p.m. |
| January 30, 2025 | | Kingston Frontenacs at Saginaw Spirit | 7:05 p.m. |
| February 1, 2025 | | Kitchener Rangers at Saginaw Spirit | 7:05 p.m. |
| February 2, 2025 | | Soo Greyhounds at Saginaw Spirit | 5:30 p.m. |
| February 5, 2025 | | Saginaw Spirit at Windsor Spitfires | 7:05 p.m. |
| February 7, 2025 | | Saginaw Spirit at Brantford Bulldogs | 7:00 p.m. |
| February 8, 2025 | | Saginaw Spirit at Guelph Storm | 7:07 p.m. |
| February 12, 2025 | | Saginaw Spirit at Soo Greyhounds | 7:07 p.m. |
| February 14, 2025 | | Windsor Spitfires at Saginaw Spirit | 7:05 p.m. |
| February 15, 2025 | | Sudbury Wolves at Saginaw Spirit | 7:05 p.m. |
| February 17, 2025 | | Saginaw Spirit at Sarnia Sting | 2:05 p.m. |
| February 20, 2025 | | North Bay Battalion at Saginaw Spirit | 7:05 p.m. |
| February 22, 2025 | | Guelph Storm at Saginaw Spirit | 7:05 p.m. |
| February 23, 2025 | | Saginaw Spirit at Windsor Spitfires | 4:05 p.m. |
| February 27, 2025 | | Saginaw Spirit at Barrie Colts | 7:00 p.m. |
| February 28, 2025 | | Saginaw Spirit at Sudbury Wolves | 7:05 p.m. |
| March 2, 2025 | | Saginaw Spirit at North Bay Battalion | 2:00 p.m. |
| March 5, 2025 | | Saginaw Spirit at Flint Firebirds | 7:00 p.m. |
| March 6, 2025 | | Barrie Colts at Saginaw Spirit | 7:05 p.m. |
| March 8, 2025 | | Brantford Bulldogs at Saginaw Spirit | 7:05 p.m. |
| March 14, 2025 | | Saginaw Spirit at London Knights | 7:00 p.m. |
| March 15, 2025 | | Windsor Spitfires at Saginaw Spirit | 7:05 p.m. |
| March 21, 2025 | | Saginaw Spirit at Soo Greyhounds | 7:07 p.m. |
| March 22, 2025 | | Saginaw Spirit at Flint Firebirds | 7:00 p.m. |
| March 23, 2025 | | Flint Firebirds at Saginaw Spirit | 5:30 p.m. |
Saginaw Spirit Schedule
