| | | |
| September 19, 2025 | W | Saginaw Spirit 5 at Soo Greyhounds 3 | Final |
| September 20, 2025 | L | Flint Firebirds 6 at Saginaw Spirit 5 | Final (OT) |
| September 26, 2025 | L | Niagara IceDogs 5 at Saginaw Spirit 4 | Final (SO) |
| September 27, 2025 | L | Guelph Storm 7 at Saginaw Spirit 3 | Final |
| October 3, 2025 | L | Saginaw Spirit 2 at Guelph Storm 3 | Final (OT) |
| October 4, 2025 | W | Saginaw Spirit 7 at Owen Sound Attack 5 | Final |
| October 5, 2025 | L | Saginaw Spirit 2 at Oshawa Generals 3 | Final (OT) |
| October 11, 2025 | L | Kitchener Rangers 3 at Saginaw Spirit 1 | Final |
| October 15, 2025 | L | Saginaw Spirit 2 at Soo Greyhounds 5 | Final |
| October 18, 2025 | L | Saginaw Spirit 4 at Flint Firebirds 5 | Final |
| October 19, 2025 | L | Flint Firebirds 4 at Saginaw Spirit 3 | Final (SO) |
| October 24, 2025 | W | Erie Otters 3 at Saginaw Spirit 5 | Final |
| October 25, 2025 | W | Owen Sound Attack 2 at Saginaw Spirit 4 | Final |
| October 26, 2025 | W | Saginaw Spirit 6 at Windsor Spitfires 5 | Final (SO) |
| October 30, 2025 | L | Flint Firebirds 5 at Saginaw Spirit 1 | Final |
| November 1, 2025 | W | Windsor Spitfires 3 at Saginaw Spirit 6 | Final |
| November 2, 2025 | L | Brantford Bulldogs 6 at Saginaw Spirit 2 | Final |
| November 7, 2025 | | Saginaw Spirit at Kitchener Rangers | 7:00 p.m. |
| November 8, 2025 | | North Bay Battalion at Saginaw Spirit | 7:05 p.m. |
| November 13, 2025 | | Saginaw Spirit at Barrie Colts | 7:00 p.m. |
| November 15, 2025 | | Saginaw Spirit at Sudbury Wolves | 7:05 p.m. |
| November 16, 2025 | | Saginaw Spirit at North Bay Battalion | 3:00 p.m. |
| November 21, 2025 | | Saginaw Spirit at Windsor Spitfires | 7:05 p.m. |
| November 22, 2025 | | Windsor Spitfires at Saginaw Spirit | 7:05 p.m. |
| November 26, 2025 | | Saginaw Spirit at Flint Firebirds | 7:00 p.m. |
| November 28, 2025 | | Saginaw Spirit at London Knights | 7:00 p.m. |
| November 29, 2025 | | London Knights at Saginaw Spirit | 7:05 p.m. |
| December 5, 2025 | | Saginaw Spirit at Guelph Storm | 7:07 p.m. |
| December 6, 2025 | | Saginaw Spirit at Brampton Steelheads | 4:00 p.m. |
| December 12, 2025 | | Saginaw Spirit at London Knights | 7:00 p.m. |
| December 13, 2025 | | Kitchener Rangers at Saginaw Spirit | 7:05 p.m. |
| December 17, 2025 | | Soo Greyhounds at Saginaw Spirit | 7:05 p.m. |
| December 20, 2025 | | Oshawa Generals at Saginaw Spirit | 7:05 p.m. |
| December 28, 2025 | | Saginaw Spirit at Soo Greyhounds | 2:07 p.m. |
| December 30, 2025 | | Sarnia Sting at Saginaw Spirit | 7:05 p.m. |
| December 31, 2025 | | Saginaw Spirit at Windsor Spitfires | 2:05 p.m. |
| January 3, 2026 | | Soo Greyhounds at Saginaw Spirit | 7:05 p.m. |
| January 4, 2026 | | Brampton Steelheads at Saginaw Spirit | 5:30 p.m. |
| January 8, 2026 | | Kingston Frontenacs at Saginaw Spirit | 7:05 p.m. |
| January 9, 2026 | | Saginaw Spirit at Flint Firebirds | 7:00 p.m. |
| January 10, 2026 | | Windsor Spitfires at Saginaw Spirit | 7:05 p.m. |
| January 16, 2026 | | Saginaw Spirit at Kitchener Rangers | 7:00 p.m. |
| January 17, 2026 | | Saginaw Spirit at Erie Otters | 7:00 p.m. |
| January 22, 2026 | | Saginaw Spirit at Peterborough Petes | 7:05 p.m. |
| January 23, 2026 | | Saginaw Spirit at Kingston Frontenacs | 7:05 p.m. |
| January 25, 2026 | | Saginaw Spirit at Ottawa 67's | 3:00 p.m. |
| January 30, 2026 | | Saginaw Spirit at Sarnia Sting | 7:05 p.m. |
| January 31, 2026 | | Barrie Colts at Saginaw Spirit | 7:05 p.m. |
| February 4, 2026 | | Soo Greyhounds at Saginaw Spirit | 7:05 p.m. |
| February 6, 2026 | | Erie Otters at Saginaw Spirit | 7:05 p.m. |
| February 7, 2026 | | London Knights at Saginaw Spirit | 7:05 p.m. |
| February 11, 2026 | | Saginaw Spirit at Flint Firebirds | 7:00 p.m. |
| February 13, 2026 | | Saginaw Spirit at Sarnia Sting | 7:05 p.m. |
| February 14, 2026 | | Windsor Spitfires at Saginaw Spirit | 7:05 p.m. |
| February 16, 2026 | | Saginaw Spirit at Windsor Spitfires | 2:05 p.m. |
| February 19, 2026 | | Sudbury Wolves at Saginaw Spirit | 7:05 p.m. |
| February 21, 2026 | | Sarnia Sting at Saginaw Spirit | 7:05 p.m. |
| February 22, 2026 | | Guelph Storm at Saginaw Spirit | 5:30 p.m. |
| February 26, 2026 | | Ottawa 67's at Saginaw Spirit | 7:05 p.m. |
| February 28, 2026 | | Peterborough Petes at Saginaw Spirit | 7:05 p.m. |
| March 5, 2026 | | Saginaw Spirit at Niagara IceDogs | 7:00 p.m. |
| March 6, 2026 | | Saginaw Spirit at Brantford Bulldogs | 7:00 p.m. |
| March 8, 2026 | | Saginaw Spirit at Erie Otters | 4:00 p.m. |
| March 14, 2026 | | Flint Firebirds at Saginaw Spirit | 7:05 p.m. |
| March 15, 2026 | | Saginaw Spirit at Sarnia Sting | 2:05 p.m. |
| March 18, 2026 | | Soo Greyhounds at Saginaw Spirit | 7:05 p.m. |
| March 20, 2026 | | Saginaw Spirit at Soo Greyhounds | 7:07 p.m. |
| March 21, 2026 | | Sarnia Sting at Saginaw Spirit | 7:05 p.m. |
Saginaw Spirit Schedule
