| | | |
| September 19, 2025 | L | Owen Sound Attack 3 at London Knights 2 | Final (OT) |
| September 20, 2025 | L | London Knights 1 at Windsor Spitfires 4 | Final |
| September 26, 2025 | L | Brampton Steelheads 2 at London Knights 1 | Final |
| September 27, 2025 | L | London Knights 3 at Erie Otters 4 | Final (OT) |
| October 3, 2025 | W | Flint Firebirds 4 at London Knights 5 | Final (OT) |
| October 4, 2025 | W | London Knights 3 at Guelph Storm 2 | Final (OT) |
| October 10, 2025 | W | Erie Otters 1 at London Knights 6 | Final |
| October 11, 2025 | W | Sarnia Sting 4 at London Knights 5 | Final (OT) |
| October 17, 2025 | W | London Knights 6 at Kitchener Rangers 1 | Final |
| October 19, 2025 | L | Kitchener Rangers 3 at London Knights 2 | Final (OT) |
| October 24, 2025 | W | Ottawa 67's 2 at London Knights 3 | Final (OT) |
| October 26, 2025 | W | London Knights 3 at Sarnia Sting 0 | Final |
| October 30, 2025 | W | London Knights 6 at Peterborough Petes 1 | Final |
| October 31, 2025 | L | London Knights 1 at Ottawa 67's 5 | Final |
| November 2, 2025 | W | London Knights 6 at Kingston Frontenacs 1 | Final |
| November 5, 2025 | L | London Knights 4 at Guelph Storm 6 | Final |
| November 7, 2025 | W | Kingston Frontenacs 1 at London Knights 2 | Final |
| November 8, 2025 | W | London Knights 3 at Owen Sound Attack 2 | Final (SO) |
| November 12, 2025 | L | London Knights 2 at Flint Firebirds 3 | Final |
| November 14, 2025 | W | Owen Sound Attack 2 at London Knights 5 | Final |
| November 16, 2025 | W | Soo Greyhounds 2 at London Knights 3 | Final (SO) |
| November 20, 2025 | L | London Knights 2 at North Bay Battalion 5 | Final |
| November 21, 2025 | L | London Knights 3 at Sudbury Wolves 6 | Final |
| November 22, 2025 | W | London Knights 4 at Soo Greyhounds 3 | Final |
| November 28, 2025 | L | Saginaw Spirit 4 at London Knights 2 | Final |
| November 29, 2025 | W | London Knights 8 at Saginaw Spirit 5 | Final |
| December 3, 2025 | L | Kitchener Rangers 4 at London Knights 3 | Final |
| December 5, 2025 | L | Windsor Spitfires 4 at London Knights 1 | Final |
| December 6, 2025 | W | London Knights 3 at Windsor Spitfires 2 | Final (OT) |
| December 11, 2025 | L | London Knights 3 at Niagara IceDogs 4 | Final |
| December 12, 2025 | W | Saginaw Spirit 3 at London Knights 5 | Final |
| December 14, 2025 | L | London Knights 0 at Brantford Bulldogs 2 | Final |
| December 17, 2025 | W | London Knights 5 at Owen Sound Attack 4 | Final (OT) |
| December 19, 2025 | W | Oshawa Generals 3 at London Knights 5 | Final |
| December 20, 2025 | W | London Knights 4 at Barrie Colts 0 | Final |
| December 28, 2025 | W | London Knights 3 at Sarnia Sting 1 | Final |
| December 31, 2025 | L | Sarnia Sting 5 at London Knights 1 | Final |
| January 2, 2026 | L | Flint Firebirds 5 at London Knights 0 | Final |
| January 4, 2026 | W | London Knights 5 at Oshawa Generals 4 | Final |
| January 9, 2026 | L | Brantford Bulldogs 4 at London Knights 1 | Final |
| January 10, 2026 | W | Erie Otters 1 at London Knights 4 | Final |
| January 16, 2026 | W | London Knights 4 at Sarnia Sting 1 | Final |
| January 17, 2026 | W | London Knights 5 at Owen Sound Attack 4 | Final |
| January 21, 2026 | L | London Knights 2 at Soo Greyhounds 5 | Final |
| January 23, 2026 | W | Sarnia Sting 2 at London Knights 3 | Final (OT) |
| January 25, 2026 | W | Peterborough Petes 2 at London Knights 10 | Final |
| January 30, 2026 | L | North Bay Battalion 3 at London Knights 2 | Final (SO) |
| January 31, 2026 | W | London Knights 6 at Erie Otters 1 | Final |
| February 4, 2026 | L | Kitchener Rangers 4 at London Knights 3 | Final (OT) |
| February 6, 2026 | W | Niagara IceDogs 4 at London Knights 5 | Final (OT) |
| February 7, 2026 | W | London Knights 5 at Saginaw Spirit 3 | Final |
| February 10, 2026 | L | London Knights 2 at Kitchener Rangers 5 | Final |
| February 11, 2026 | L | Guelph Storm 4 at London Knights 2 | Final |
| February 13, 2026 | W | Soo Greyhounds 3 at London Knights 4 | Final (SO) |
| February 16, 2026 | W | Owen Sound Attack 2 at London Knights 6 | Final |
| February 20, 2026 | L | Barrie Colts 5 at London Knights 1 | Final |
| February 22, 2026 | W | Sudbury Wolves 2 at London Knights 4 | Final |
| February 27, 2026 | L | Windsor Spitfires 6 at London Knights 1 | Final |
| February 28, 2026 | W | London Knights 5 at Brampton Steelheads 0 | Final |
| March 1, 2026 | L | London Knights 1 at Kitchener Rangers 4 | Final |
| March 4, 2026 | W | Guelph Storm 2 at London Knights 5 | Final |
| March 6, 2026 | W | Erie Otters 2 at London Knights 10 | Final |
| March 7, 2026 | W | London Knights 3 at Erie Otters 1 | Final |
| March 13, 2026 | W | Guelph Storm 3 at London Knights 4 | Final |
| March 15, 2026 | | London Knights at Windsor Spitfires | 4:05 p.m. |
| March 18, 2026 | | London Knights at Guelph Storm | 6:37 p.m. |
| March 20, 2026 | | Windsor Spitfires at London Knights | 7:00 p.m. |
| March 21, 2026 | | London Knights at Flint Firebirds | 7:00 p.m. |
London Knights Schedule
