| | | |
| February 21, 2026 | W | Atlanta United FC 0 at FC Cincinnati 2 | Final |
| February 28, 2026 | L | FC Cincinnati 0 at Minnesota United FC 1 | Final |
| March 8, 2026 | L | Toronto FC 1 at FC Cincinnati 0 | Final |
| March 15, 2026 | L | FC Cincinnati 1 at New England Revolution 6 | Final |
| March 22, 2026 | W | Club de Foot Montreal 3 at FC Cincinnati 4 | Final |
| April 4, 2026 | L | FC Cincinnati 2 at Red Bull New York 4 | Final |
| April 11, 2026 | | FC Cincinnati at Toronto FC | 12:00 p.m. |
| April 18, 2026 | | Chicago Fire FC at FC Cincinnati | 6:30 p.m. |
| April 22, 2026 | | FC Cincinnati at New York City FC | 6:30 p.m. |
| April 25, 2026 | | Red Bull New York at FC Cincinnati | 6:30 p.m. |
| May 2, 2026 | | FC Cincinnati at Chicago Fire FC | 7:30 p.m. |
| May 9, 2026 | | FC Cincinnati at Charlotte FC | 6:30 p.m. |
| May 13, 2026 | | Inter Miami CF at FC Cincinnati | 6:30 p.m. |
| May 16, 2026 | | FC Cincinnati at San Diego FC | 8:30 p.m. |
| May 23, 2026 | | Orlando City SC at FC Cincinnati | 6:30 p.m. |
| July 22, 2026 | | Vancouver Whitecaps FC at FC Cincinnati | 6:30 p.m. |
| July 25, 2026 | | FC Cincinnati at Columbus Crew SC | 6:00 p.m. |
| August 1, 2026 | | San Jose Earthquakes at FC Cincinnati | 6:30 p.m. |
| August 15, 2026 | | FC Cincinnati at Orlando City SC | 6:30 p.m. |
| August 19, 2026 | | New York City FC at FC Cincinnati | 6:30 p.m. |
| August 22, 2026 | | Seattle Sounders FC at FC Cincinnati | 6:30 p.m. |
| August 29, 2026 | | FC Cincinnati at Nashville SC | 7:30 p.m. |
| September 5, 2026 | | D.C. United at FC Cincinnati | 6:30 p.m. |
| September 9, 2026 | | FC Cincinnati at Philadelphia Union | 6:30 p.m. |
| September 12, 2026 | | Charlotte FC at FC Cincinnati | 6:30 p.m. |
| September 19, 2026 | | FC Cincinnati at Houston Dynamo FC | 7:30 p.m. |
| September 26, 2026 | | FC Cincinnati at Club de Foot Montreal | 6:30 p.m. |
| October 10, 2026 | | FC Cincinnati at Atlanta United FC | 6:30 p.m. |
| October 14, 2026 | | New England Revolution at FC Cincinnati | 6:30 p.m. |
| October 18, 2026 | | Columbus Crew SC at FC Cincinnati | 6:00 p.m. |
| October 24, 2026 | | FC Cincinnati at D.C. United | 6:30 p.m. |
| October 28, 2026 | | FC Cincinnati at Inter Miami CF | 6:30 p.m. |
| October 31, 2026 | | Philadelphia Union at FC Cincinnati | 1:00 p.m. |
| November 7, 2026 | | Nashville SC at FC Cincinnati | 4:00 p.m. |
FC Cincinnati Schedule
