| | | |
| February 22, 2026 | L | Colorado Rapids 0 at Seattle Sounders FC 2 | Final |
| February 28, 2026 | W | Portland Timbers 0 at Colorado Rapids 2 | Final |
| March 7, 2026 | W | LA Galaxy 1 at Colorado Rapids 4 | Final |
| March 14, 2026 | L | Colorado Rapids 1 at New York City FC 3 | Final |
| March 21, 2026 | W | Colorado Rapids 4 at Sporting Kansas City 1 | Final |
| April 4, 2026 | L | Colorado Rapids 2 at Toronto FC 3 | Final |
| April 11, 2026 | W | Houston Dynamo FC 2 at Colorado Rapids 6 | Final |
| April 18, 2026 | L | Inter Miami CF 3 at Colorado Rapids 2 | Final |
| April 22, 2026 | T | Colorado Rapids 0 at Los Angeles FC 0 | Final |
| April 25, 2026 | L | Colorado Rapids 1 at Vancouver Whitecaps FC 3 | Final |
| May 2, 2026 | L | Colorado Rapids 0 at Houston Dynamo FC 1 | Final |
| May 9, 2026 | L | St. Louis City SC 1 at Colorado Rapids 0 | Final |
| May 13, 2026 | W | Colorado Rapids 1 at Minnesota United FC 0 | Final |
| May 16, 2026 | L | Colorado Rapids 1 at Real Salt Lake 2 | Final |
| May 23, 2026 | L | FC Dallas 2 at Colorado Rapids 1 | Final |
| July 22, 2026 | | San Diego FC at Colorado Rapids | 8:30 p.m. |
| July 25, 2026 | | Colorado Rapids at St. Louis City SC | 7:30 p.m. |
| August 1, 2026 | | Austin FC at Colorado Rapids | 8:30 p.m. |
| August 15, 2026 | | Sporting Kansas City at Colorado Rapids | 8:30 p.m. |
| August 19, 2026 | | Los Angeles FC at Colorado Rapids | 8:30 p.m. |
| August 22, 2026 | | Colorado Rapids at San Diego FC | 9:30 p.m. |
| August 29, 2026 | | Real Salt Lake at Colorado Rapids | 8:30 p.m. |
| September 5, 2026 | | Colorado Rapids at Columbus Crew SC | 6:30 p.m. |
| September 9, 2026 | | Colorado Rapids at Austin FC | 7:30 p.m. |
| September 12, 2026 | | Club de Foot Montreal at Colorado Rapids | 8:30 p.m. |
| September 19, 2026 | | Seattle Sounders FC at Colorado Rapids | 8:30 p.m. |
| September 26, 2026 | | Colorado Rapids at LA Galaxy | 9:30 p.m. |
| October 10, 2026 | | San Jose Earthquakes at Colorado Rapids | 8:30 p.m. |
| October 14, 2026 | | Minnesota United FC at Colorado Rapids | 8:30 p.m. |
| October 17, 2026 | | Colorado Rapids at Portland Timbers | 9:30 p.m. |
| October 24, 2026 | | Vancouver Whitecaps FC at Colorado Rapids | 8:30 p.m. |
| October 28, 2026 | | Colorado Rapids at San Jose Earthquakes | 9:30 p.m. |
| October 31, 2026 | | Chicago Fire FC at Colorado Rapids | 8:30 p.m. |
| November 7, 2026 | | Colorado Rapids at FC Dallas | 7:00 p.m. |
Colorado Rapids Schedule
