| | | |
| February 21, 2026 | T | Charlotte FC 1 at St. Louis City SC 1 | Final |
| February 28, 2026 | L | Charlotte FC 0 at LA Galaxy 3 | Final |
| March 7, 2026 | W | Austin FC 1 at Charlotte FC 3 | Final |
| March 14, 2026 | T | Inter Miami CF 0 at Charlotte FC 0 | Final |
| March 21, 2026 | W | Red Bull New York 1 at Charlotte FC 6 | Final |
| April 4, 2026 | W | Philadelphia Union 1 at Charlotte FC 2 | Final |
| April 11, 2026 | | Nashville SC at Charlotte FC | 6:30 p.m. |
| April 18, 2026 | | Charlotte FC at New York City FC | 6:30 p.m. |
| April 22, 2026 | | Charlotte FC at Orlando City SC | 6:30 p.m. |
| April 25, 2026 | | Charlotte FC at Nashville SC | 7:30 p.m. |
| May 2, 2026 | | Charlotte FC at New England Revolution | 6:30 p.m. |
| May 9, 2026 | | FC Cincinnati at Charlotte FC | 6:30 p.m. |
| May 13, 2026 | | New York City FC at Charlotte FC | 6:00 p.m. |
| May 16, 2026 | | Toronto FC at Charlotte FC | 6:30 p.m. |
| May 23, 2026 | | New England Revolution at Charlotte FC | 6:30 p.m. |
| July 22, 2026 | | Atlanta United FC at Charlotte FC | 7:00 p.m. |
| July 25, 2026 | | Charlotte FC at Red Bull New York | 6:30 p.m. |
| August 1, 2026 | | Charlotte FC at Chicago Fire FC | 7:30 p.m. |
| August 15, 2026 | | Columbus Crew SC at Charlotte FC | 6:30 p.m. |
| August 19, 2026 | | Charlotte FC at Toronto FC | 6:30 p.m. |
| August 22, 2026 | | D.C. United at Charlotte FC | 6:30 p.m. |
| August 29, 2026 | | Charlotte FC at Atlanta United FC | 6:30 p.m. |
| September 5, 2026 | | Houston Dynamo FC at Charlotte FC | 6:30 p.m. |
| September 9, 2026 | | Charlotte FC at Club de Foot Montreal | 6:30 p.m. |
| September 12, 2026 | | Charlotte FC at FC Cincinnati | 6:30 p.m. |
| September 19, 2026 | | Charlotte FC at D.C. United | 6:30 p.m. |
| September 26, 2026 | | Chicago Fire FC at Charlotte FC | 6:30 p.m. |
| October 10, 2026 | | FC Dallas at Charlotte FC | 6:30 p.m. |
| October 14, 2026 | | Charlotte FC at Columbus Crew SC | 6:30 p.m. |
| October 17, 2026 | | Charlotte FC at Philadelphia Union | 1:30 p.m. |
| October 24, 2026 | | Charlotte FC at Portland Timbers | 9:30 p.m. |
| October 28, 2026 | | Club de Foot Montreal at Charlotte FC | 6:30 p.m. |
| October 31, 2026 | | Orlando City SC at Charlotte FC | 12:00 p.m. |
| November 7, 2026 | | Charlotte FC at Inter Miami CF | 4:00 p.m. |
Charlotte FC Schedule
