Orlando City SC Schedule
All times Eastern
Complete Schedule
| February 22, 2025 | L | Philadelphia Union 4 at Orlando City SC 2 | Final |
| March 1, 2025 | W | Toronto FC 2 at Orlando City SC 4 | Final |
| March 8, 2025 | L | Orlando City SC 1 at New York City FC 2 | Final |
| March 15, 2025 | T | Orlando City SC 2 at New York Red Bulls 2 | Final |
| March 22, 2025 | W | D.C. United 1 at Orlando City SC 4 | Final |
| March 29, 2025 | W | Orlando City SC 2 at LA Galaxy 1 | Final |
| April 5, 2025 | T | Orlando City SC 0 at Philadelphia Union 0 | Final |
| April 12, 2025 | T | New York Red Bulls 0 at Orlando City SC 0 | Final |
| April 19, 2025 | T | Orlando City SC 0 at Club de Foot Montreal 0 | Final |
| April 26, 2025 | W | Atlanta United FC 0 at Orlando City SC 3 | Final |
| May 3, 2025 | T | Orlando City SC 0 at Chicago Fire FC 0 | Final |
| May 10, 2025 | T | New England Revolution 3 at Orlando City SC 3 | Final |
| May 14, 2025 | W | Charlotte FC 1 at Orlando City SC 3 | Final |
| May 18, 2025 | W | Orlando City SC 3 at Inter Miami CF 0 | Final |
| May 24, 2025 | W | Portland Timbers 0 at Orlando City SC 1 | Final |
| May 28, 2025 | L | Orlando City SC 2 at Atlanta United FC 3 | Final |
| May 31, 2025 | L | Chicago Fire FC 3 at Orlando City SC 1 | Final |
| June 14, 2025 | W | Orlando City SC 1 at Colorado Rapids 0 | Final |
| June 25, 2025 | W | Orlando City SC 4 at St. Louis City SC 2 | Final |
| June 28, 2025 | L | FC Cincinnati 2 at Orlando City SC 1 | Final |
| July 5, 2025 | T | Orlando City SC 2 at Charlotte FC 2 | Final |
| July 12, 2025 | T | Club de Foot Montreal 1 at Orlando City SC 1 | Final |
| July 16, 2025 | L | New York City FC 2 at Orlando City SC 1 | Final |
| July 19, 2025 | W | Orlando City SC 2 at New England Revolution 1 | Final |
| July 25, 2025 | W | Orlando City SC 3 at Columbus Crew SC 1 | Final |
| August 10, 2025 | W | Inter Miami CF 1 at Orlando City SC 4 | Final |
| August 16, 2025 | W | Sporting Kansas City 1 at Orlando City SC 3 | Final |
| August 23, 2025 | L | Orlando City SC 1 at Nashville SC 5 | Final |
| September 13, 2025 | T | Orlando City SC 1 at D.C. United 1 | Final |
| September 20, 2025 | W | Nashville SC 2 at Orlando City SC 3 | Final |
| September 28, 2025 | T | Orlando City SC 1 at FC Cincinnati 1 | Final |
| October 4, 2025 | T | Columbus Crew SC 1 at Orlando City SC 1 | Final |
| October 11, 2025 | L | Vancouver Whitecaps FC 2 at Orlando City SC 1 | Final |
| October 18, 2025 | L | Orlando City SC 2 at Toronto FC 4 | Final |
| October 22, 2025 | L | Orlando City SC 1 at Chicago Fire FC 3 (Playoff) | Final |
