| | | |
| February 22, 2025 | L | Minnesota United FC 0 at Los Angeles FC 1 | Final |
| March 1, 2025 | W | Club de Foot Montreal 0 at Minnesota United FC 1 | Final |
| March 8, 2025 | W | Minnesota United FC 1 at San Jose Earthquakes 0 | Final |
| March 15, 2025 | T | Minnesota United FC 3 at Sporting Kansas City 3 | Final |
| March 22, 2025 | T | LA Galaxy 2 at Minnesota United FC 2 | Final |
| March 29, 2025 | W | Real Salt Lake 0 at Minnesota United FC 2 | Final |
| April 6, 2025 | W | Minnesota United FC 2 at New York City FC 1 | Final |
| April 12, 2025 | T | Minnesota United FC 0 at Toronto FC 0 | Final |
| April 19, 2025 | T | FC Dallas 0 at Minnesota United FC 0 | Final |
| April 27, 2025 | L | Vancouver Whitecaps FC 3 at Minnesota United FC 1 | Final |
| May 3, 2025 | W | Minnesota United FC 3 at Austin FC 0 | Final |
| May 10, 2025 | W | Inter Miami CF 1 at Minnesota United FC 4 | Final |
| May 14, 2025 | L | Minnesota United FC 0 at Houston Dynamo FC 2 | Final |
| May 17, 2025 | W | St. Louis City SC 0 at Minnesota United FC 3 | Final |
| May 24, 2025 | T | Austin FC 1 at Minnesota United FC 1 | Final |
| May 28, 2025 | T | Minnesota United FC 0 at Vancouver Whitecaps FC 0 | Final |
| June 1, 2025 | W | Minnesota United FC 3 at Seattle Sounders FC 2 | Final |
| June 14, 2025 | L | San Diego FC 4 at Minnesota United FC 2 | Final |
| June 25, 2025 | W | Houston Dynamo FC 1 at Minnesota United FC 3 | Final |
| June 28, 2025 | T | Minnesota United FC 2 at New York Red Bulls 2 | Final |
| July 4, 2025 | W | Minnesota United FC 2 at FC Dallas 1 | Final |
| July 12, 2025 | W | San Jose Earthquakes 1 at Minnesota United FC 4 | Final |
| July 16, 2025 | L | Los Angeles FC 1 at Minnesota United FC 0 | Final |
| July 19, 2025 | T | Minnesota United FC 1 at Portland Timbers 1 | Final |
| July 26, 2025 | W | Minnesota United FC 2 at St. Louis City SC 1 | Final |
| August 10, 2025 | L | Colorado Rapids 2 at Minnesota United FC 1 | Final |
| August 16, 2025 | W | Seattle Sounders FC 0 at Minnesota United FC 1 | Final |
| August 23, 2025 | W | Minnesota United FC 3 at Real Salt Lake 1 | Final |
| August 30, 2025 | T | Portland Timbers 1 at Minnesota United FC 1 | Final |
| September 13, 2025 | W | Minnesota United FC 3 at San Diego FC 1 | Final |
| September 20, 2025 | L | Chicago Fire FC 3 at Minnesota United FC 0 | Final |
| September 27, 2025 | T | Minnesota United FC 1 at Colorado Rapids 1 | Final |
| October 4, 2025 | W | Sporting Kansas City 0 at Minnesota United FC 3 | Final |
| October 18, 2025 | L | Minnesota United FC 1 at LA Galaxy 2 | Final |
| October 27, 2025 | T | Seattle Sounders FC 0 at Minnesota United FC 0 (Playoff Gm. 1) | Final (PK 2-3) |
| November 3, 2025 | L | Minnesota United FC 2 at Seattle Sounders FC 4 (Playoff Gm. 2) | Final |
| November 8, 2025 | T | Seattle Sounders FC 3 at Minnesota United FC 3 (Playoff Gm. 3) | Final (PK 6-7) |
| November 24, 2025 | L | Minnesota United FC 0 at San Diego FC 1 (Playoff) | Final |
Minnesota United FC Schedule
