| | | |
| February 22, 2025 | L | Minnesota United FC 0 at Los Angeles FC 1 | Final |
| March 1, 2025 | W | Club de Foot Montreal 0 at Minnesota United FC 1 | Final |
| March 8, 2025 | W | Minnesota United FC 1 at San Jose Earthquakes 0 | Final |
| March 15, 2025 | T | Minnesota United FC 3 at Sporting Kansas City 3 | Final |
| March 22, 2025 | T | LA Galaxy 2 at Minnesota United FC 2 | Final |
| March 29, 2025 | W | Real Salt Lake 0 at Minnesota United FC 2 | Final |
| April 6, 2025 | W | Minnesota United FC 2 at New York City FC 1 | Final |
| April 12, 2025 | T | Minnesota United FC 0 at Toronto FC 0 | Final |
| April 19, 2025 | T | FC Dallas 0 at Minnesota United FC 0 | Final |
| April 27, 2025 | L | Vancouver Whitecaps FC 3 at Minnesota United FC 1 | Final |
| May 3, 2025 | W | Minnesota United FC 3 at Austin FC 0 | Final |
| May 10, 2025 | W | Inter Miami CF 1 at Minnesota United FC 4 | Final |
| May 14, 2025 | L | Minnesota United FC 0 at Houston Dynamo FC 2 | Final |
| May 17, 2025 | W | St. Louis City SC 0 at Minnesota United FC 3 | Final |
| May 24, 2025 | T | Austin FC 1 at Minnesota United FC 1 | Final |
| May 28, 2025 | T | Minnesota United FC 0 at Vancouver Whitecaps FC 0 | Final |
| June 1, 2025 | W | Minnesota United FC 3 at Seattle Sounders FC 2 | Final |
| June 14, 2025 | L | San Diego FC 4 at Minnesota United FC 2 | Final |
| June 25, 2025 | | Houston Dynamo FC at Minnesota United FC | 8:30 p.m. |
| June 28, 2025 | | Minnesota United FC at New York Red Bulls | 7:30 p.m. |
| July 4, 2025 | | Minnesota United FC at FC Dallas | 8:30 p.m. |
| July 12, 2025 | | San Jose Earthquakes at Minnesota United FC | 8:30 p.m. |
| July 16, 2025 | | Los Angeles FC at Minnesota United FC | 8:30 p.m. |
| July 19, 2025 | | Minnesota United FC at Portland Timbers | 10:30 p.m. |
| July 26, 2025 | | Minnesota United FC at St. Louis City SC | 8:30 p.m. |
| August 10, 2025 | | Colorado Rapids at Minnesota United FC | 6:00 p.m. |
| August 16, 2025 | | Seattle Sounders FC at Minnesota United FC | 8:30 p.m. |
| August 23, 2025 | | Minnesota United FC at Real Salt Lake | 9:30 p.m. |
| August 30, 2025 | | Portland Timbers at Minnesota United FC | 8:30 p.m. |
| September 13, 2025 | | Minnesota United FC at San Diego FC | 10:30 p.m. |
| September 20, 2025 | | Chicago Fire FC at Minnesota United FC | 8:30 p.m. |
| September 27, 2025 | | Minnesota United FC at Colorado Rapids | 9:30 p.m. |
| October 4, 2025 | | Sporting Kansas City at Minnesota United FC | 8:30 p.m. |
| October 18, 2025 | | Minnesota United FC at LA Galaxy | 9:00 p.m. |
Minnesota United FC Schedule
