| | | |
| March 16, 2019 | L | Pittsburgh Riverhounds SC 0 at Tampa Bay Rowdies 2 | Final |
| March 23, 2019 | T | Pittsburgh Riverhounds SC 2 at Swope Park Rangers 2 | Final |
| March 30, 2019 | T | Pittsburgh Riverhounds SC 2 at Bethlehem Steel FC 2 | Final |
| April 6, 2019 | W | Pittsburgh Riverhounds SC 1 at Louisville City FC 0 | Final |
| April 13, 2019 | W | Hartford Athletic 1 at Pittsburgh Riverhounds SC 3 | Final |
| April 20, 2019 | | Saint Louis FC at Pittsburgh Riverhounds SC | 7:00 p.m. |
| April 27, 2019 | | Nashville SC at Pittsburgh Riverhounds SC | 7:00 p.m. |
| May 4, 2019 | | Pittsburgh Riverhounds SC at Charleston Battery | 7:30 p.m. |
| May 18, 2019 | | Pittsburgh Riverhounds SC at Memphis 901 FC | 8:00 p.m. |
| May 25, 2019 | | Charlotte Independence at Pittsburgh Riverhounds SC | 7:00 p.m. |
| June 1, 2019 | | Pittsburgh Riverhounds SC at Indy Eleven | 7:00 p.m. |
| June 8, 2019 | | Ottawa Fury FC at Pittsburgh Riverhounds SC | 7:00 p.m. |
| June 15, 2019 | | Pittsburgh Riverhounds SC at Atlanta United 2 | 7:30 p.m. |
| June 22, 2019 | | New York Red Bulls II at Pittsburgh Riverhounds SC | 7:00 p.m. |
| June 29, 2019 | | Birmingham Legion FC at Pittsburgh Riverhounds SC | 7:00 p.m. |
| July 4, 2019 | | Bethlehem Steel FC at Pittsburgh Riverhounds SC | 7:00 p.m. |
| July 7, 2019 | | Pittsburgh Riverhounds SC at Charlotte Independence | 7:00 p.m. |
| July 13, 2019 | | Tampa Bay Rowdies at Pittsburgh Riverhounds SC | 7:00 p.m. |
| July 20, 2019 | | North Carolina FC at Pittsburgh Riverhounds SC | 7:00 p.m. |
| July 27, 2019 | | Pittsburgh Riverhounds SC at Hartford Athletic | 7:00 p.m. |
| August 3, 2019 | | Memphis 901 FC at Pittsburgh Riverhounds SC | 7:00 p.m. |
| August 10, 2019 | | Swope Park Rangers at Pittsburgh Riverhounds SC | 7:00 p.m. |
| August 14, 2019 | | Pittsburgh Riverhounds SC at New York Red Bulls II | 7:00 p.m. |
| August 17, 2019 | | Pittsburgh Riverhounds SC at North Carolina FC | 7:00 p.m. |
| August 23, 2019 | | Loudoun United at Pittsburgh Riverhounds SC | 7:00 p.m. |
| August 30, 2019 | | Pittsburgh Riverhounds SC at Ottawa Fury FC | 7:00 p.m. |
| September 7, 2019 | | Louisville City FC at Pittsburgh Riverhounds SC | 7:00 p.m. |
| September 14, 2019 | | Charleston Battery at Pittsburgh Riverhounds SC | 7:00 p.m. |
| September 21, 2019 | | Pittsburgh Riverhounds SC at Nashville SC | 8:00 p.m. |
| September 28, 2019 | | Indy Eleven at Pittsburgh Riverhounds SC | 7:00 p.m. |
| October 1, 2019 | | Pittsburgh Riverhounds SC at Loudoun United | 7:30 p.m. |
| October 5, 2019 | | Atlanta United 2 at Pittsburgh Riverhounds SC | 7:00 p.m. |
| October 12, 2019 | | Pittsburgh Riverhounds SC at Saint Louis FC | 8:30 p.m. |
| October 20, 2019 | | Pittsburgh Riverhounds SC at Birmingham Legion FC | 4:30 p.m. |
Pittsburgh Riverhounds SC Schedule
