| | | |
| November 7, 2025 | W | Cleveland Charge 124 at Iowa Wolves 137 | Final |
| November 8, 2025 | W | Cleveland Charge 123 at Iowa Wolves 130 | Final |
| November 13, 2025 | L | Iowa Wolves 113 at Grand Rapids Gold 121 | Final |
| November 16, 2025 | W | Noblesville Boom 133 at Iowa Wolves 137 | Final |
| November 17, 2025 | W | Noblesville Boom 120 at Iowa Wolves 133 | Final |
| November 20, 2025 | L | Windy City Bulls 144 at Iowa Wolves 140 | Final |
| November 21, 2025 | W | Windy City Bulls 128 at Iowa Wolves 156 | Final |
| November 29, 2025 | W | Iowa Wolves 156 at Motor City Cruise 137 | Final |
| December 4, 2025 | L | Iowa Wolves 124 at Grand Rapids Gold 134 | Final |
| December 6, 2025 | L | Iowa Wolves 121 at Sioux Falls Skyforce 133 | Final |
| December 7, 2025 | W | Iowa Wolves 115 at Sioux Falls Skyforce 110 | Final |
| December 12, 2025 | L | Motor City Cruise 121 at Iowa Wolves 101 | Final |
| December 14, 2025 | L | Iowa Wolves 102 at Wisconsin Herd 107 | Final |
| December 16, 2025 | W | Iowa Wolves 110 at Wisconsin Herd 108 | Final |
| December 20, 2025 | W | Birmingham Squadron 101 at Iowa Wolves 117 (Orlando) | Final |
| December 22, 2025 | W | Iowa Wolves 132 at Westchester Knicks 104 (Orlando) | Final |
| December 27, 2025 | L | Iowa Wolves 117 at Greensboro Swarm 123 | Final |
| December 29, 2025 | W | Iowa Wolves 136 at Delaware Blue Coats 115 | Final |
| December 31, 2025 | L | Iowa Wolves 118 at Delaware Blue Coats 119 | Final |
| January 3, 2026 | L | Sioux Falls Skyforce 120 at Iowa Wolves 114 | Final |
| January 4, 2026 | W | Sioux Falls Skyforce 110 at Iowa Wolves 120 | Final |
| January 9, 2026 | L | Iowa Wolves 118 at San Diego Clippers 125 | Final |
| January 10, 2026 | W | Iowa Wolves 105 at San Diego Clippers 98 | Final |
| January 13, 2026 | W | Iowa Wolves 130 at Valley Suns 123 | Final |
| January 15, 2026 | W | Iowa Wolves 137 at Valley Suns 127 | Final |
| January 18, 2026 | L | Long Island Nets 124 at Iowa Wolves 115 | Final |
| January 19, 2026 | L | Long Island Nets 108 at Iowa Wolves 106 | Final |
| January 24, 2026 | W | Memphis Hustle 109 at Iowa Wolves 127 | Final |
| January 26, 2026 | W | Rio Grande Valley Vipers 129 at Iowa Wolves 136 | Final |
| January 27, 2026 | W | Mexico City Capitanes 104 at Iowa Wolves 113 | Final |
| January 30, 2026 | L | Iowa Wolves 101 at Santa Cruz Warriors 108 | Final |
| January 31, 2026 | W | Iowa Wolves 127 at Santa Cruz Warriors 123 | Final (OT) |
| February 3, 2026 | W | Iowa Wolves 114 at Stockton Kings 109 | Final |
| February 7, 2026 | W | Maine Celtics 120 at Iowa Wolves 123 | Final |
| February 10, 2026 | L | Austin Spurs 130 at Iowa Wolves 124 | Final |
| February 11, 2026 | L | Austin Spurs 135 at Iowa Wolves 120 | Final |
| February 22, 2026 | L | Rio Grande Valley Vipers 117 at Iowa Wolves 115 | Final |
| February 25, 2026 | L | Iowa Wolves 118 at Stockton Kings 131 | Final |
| February 27, 2026 | W | Mexico City Capitanes 117 at Iowa Wolves 118 | Final |
| March 2, 2026 | W | Iowa Wolves 122 at Rip City Remix 95 | Final |
| March 4, 2026 | W | Iowa Wolves 136 at Rip City Remix 117 | Final |
| March 8, 2026 | L | Memphis Hustle 142 at Iowa Wolves 132 | Final |
| March 11, 2026 | L | Iowa Wolves 116 at South Bay Lakers 123 | Final |
| March 13, 2026 | L | Iowa Wolves 106 at South Bay Lakers 125 | Final |
| March 16, 2026 | W | Salt Lake City Stars 106 at Iowa Wolves 132 | Final |
| March 18, 2026 | W | Salt Lake City Stars 110 at Iowa Wolves 132 | Final |
| March 20, 2026 | W | Iowa Wolves 110 at Texas Legends 103 | Final |
| March 22, 2026 | L | Iowa Wolves 106 at Texas Legends 109 | Final |
| March 26, 2026 | W | Oklahoma City Blue 106 at Iowa Wolves 133 | Final |
| March 28, 2026 | | Oklahoma City Blue at Iowa Wolves | 7:30 p.m. |
Iowa Wolves Schedule
