| | | |
| October 23, 2021 | W | Greenville Swamp Rabbits 2 at South Carolina Stingrays 4 | Final |
| October 30, 2021 | L | South Carolina Stingrays 2 at Greenville Swamp Rabbits 4 | Final |
| November 3, 2021 | W | Greenville Swamp Rabbits 0 at South Carolina Stingrays 1 | Final |
| November 6, 2021 | W | South Carolina Stingrays 5 at Jacksonville Icemen 2 | Final |
| November 7, 2021 | W | Jacksonville Icemen 3 at South Carolina Stingrays 4 | Final (SO) |
| November 12, 2021 | L | Atlanta Gladiators 4 at South Carolina Stingrays 2 | Final |
| November 13, 2021 | W | Orlando Solar Bears 2 at South Carolina Stingrays 4 | Final |
| November 14, 2021 | L | Orlando Solar Bears 6 at South Carolina Stingrays 3 | Final |
| November 17, 2021 | L | South Carolina Stingrays 0 at Norfolk Admirals 3 | Final |
| November 19, 2021 | L | South Carolina Stingrays 0 at Greenville Swamp Rabbits 2 | Final |
| November 23, 2021 | L | South Carolina Stingrays 3 at Jacksonville Icemen 4 | Final |
| November 26, 2021 | L | Greenville Swamp Rabbits 4 at South Carolina Stingrays 3 | Final (OT) |
| November 27, 2021 | W | South Carolina Stingrays 2 at Atlanta Gladiators 1 | Final |
| November 28, 2021 | W | Atlanta Gladiators 3 at South Carolina Stingrays 4 | Final (OT) |
| December 3, 2021 | L | Greenville Swamp Rabbits 7 at South Carolina Stingrays 6 | Final (OT) |
| December 4, 2021 | W | Greenville Swamp Rabbits 3 at South Carolina Stingrays 4 | Final (SO) |
| December 5, 2021 | W | South Carolina Stingrays 2 at Greenville Swamp Rabbits 1 | Final (OT) |
| December 8, 2021 | L | South Carolina Stingrays 0 at Idaho Steelheads 3 | Final |
| December 10, 2021 | L | South Carolina Stingrays 1 at Idaho Steelheads 3 | Final |
| December 11, 2021 | L | South Carolina Stingrays 1 at Idaho Steelheads 4 | Final |
| December 17, 2021 | L | Toledo Walleye 2 at South Carolina Stingrays 1 | Final |
| December 18, 2021 | L | Jacksonville Icemen 3 at South Carolina Stingrays 1 | Final |
| December 19, 2021 | L | Jacksonville Icemen 5 at South Carolina Stingrays 2 | Final |
| December 26, 2021 | L | Jacksonville Icemen 3 at South Carolina Stingrays 1 | Final |
| December 29, 2021 | L | South Carolina Stingrays 2 at Jacksonville Icemen 6 | Final |
| December 31, 2021 | L | South Carolina Stingrays 4 at Orlando Solar Bears 5 | Final (OT) |
| January 1, 2022 | W | South Carolina Stingrays 1 at Jacksonville Icemen 0 | Final |
| January 2, 2022 | L | Jacksonville Icemen 3 at South Carolina Stingrays 1 | Final |
| January 7, 2022 | L | South Carolina Stingrays 3 at Florida Everblades 8 | Final |
| January 8, 2022 | L | South Carolina Stingrays 2 at Florida Everblades 5 | Final |
| January 10, 2022 | L | South Carolina Stingrays 1 at Orlando Solar Bears 2 | Final |
| January 14, 2022 | W | Norfolk Admirals 4 at South Carolina Stingrays 6 | Final |
| January 15, 2022 | W | Norfolk Admirals 1 at South Carolina Stingrays 2 | Final |
| January 21, 2022 | L | South Carolina Stingrays 1 at Jacksonville Icemen 2 | Final |
| January 22, 2022 | L | South Carolina Stingrays 0 at Jacksonville Icemen 1 | Final (OT) |
| January 23, 2022 | W | Jacksonville Icemen 3 at South Carolina Stingrays 6 | Final |
| January 26, 2022 | L | South Carolina Stingrays 2 at Greenville Swamp Rabbits 7 | Final |
| January 28, 2022 | L | South Carolina Stingrays 4 at Norfolk Admirals 6 | Final |
| January 29, 2022 | L | South Carolina Stingrays 1 at Norfolk Admirals 4 | Final |
| January 30, 2022 | W | South Carolina Stingrays 2 at Norfolk Admirals 1 | Final (SO) |
| February 5, 2022 | W | South Carolina Stingrays 5 at Greenville Swamp Rabbits 1 | Final |
| February 11, 2022 | W | Norfolk Admirals 1 at South Carolina Stingrays 3 | Final |
| February 12, 2022 | L | Norfolk Admirals 5 at South Carolina Stingrays 2 | Final |
| February 15, 2022 | L | Greenville Swamp Rabbits 6 at South Carolina Stingrays 2 | Final |
| February 18, 2022 | L | South Carolina Stingrays 3 at Florida Everblades 4 | Final (OT) |
| February 19, 2022 | L | South Carolina Stingrays 3 at Florida Everblades 4 | Final |
| February 20, 2022 | L | South Carolina Stingrays 2 at Jacksonville Icemen 5 | Final |
| February 23, 2022 | W | South Carolina Stingrays 4 at Greenville Swamp Rabbits 1 | Final |
| February 24, 2022 | L | South Carolina Stingrays 2 at Atlanta Gladiators 6 | Final |
| February 26, 2022 | L | Florida Everblades 6 at South Carolina Stingrays 5 | Final (OT) |
| February 27, 2022 | L | Florida Everblades 3 at South Carolina Stingrays 1 | Final |
| March 4, 2022 | L | Orlando Solar Bears 4 at South Carolina Stingrays 3 | Final |
| March 5, 2022 | W | Orlando Solar Bears 2 at South Carolina Stingrays 5 | Final |
| March 6, 2022 | L | Atlanta Gladiators 4 at South Carolina Stingrays 3 | Final |
| March 11, 2022 | L | Greenville Swamp Rabbits 4 at South Carolina Stingrays 1 | Final |
| March 12, 2022 | L | Norfolk Admirals 3 at South Carolina Stingrays 2 | Final |
| March 13, 2022 | L | South Carolina Stingrays 1 at Atlanta Gladiators 3 | Final |
| March 16, 2022 | W | Greenville Swamp Rabbits 0 at South Carolina Stingrays 1 | Final |
| March 18, 2022 | L | South Carolina Stingrays 0 at Worcester Railers HC 3 | Final |
| March 19, 2022 | W | South Carolina Stingrays 2 at Maine Mariners 0 | Final |
| March 20, 2022 | L | South Carolina Stingrays 0 at Maine Mariners 4 | Final |
| March 25, 2022 | W | Trois-Rivieres Lions 0 at South Carolina Stingrays 3 | Final |
| March 26, 2022 | L | Trois-Rivieres Lions 5 at South Carolina Stingrays 2 | Final |
| March 27, 2022 | W | Trois-Rivieres Lions 4 at South Carolina Stingrays 5 | Final (OT) |
| March 30, 2022 | W | South Carolina Stingrays 5 at Greenville Swamp Rabbits 4 | Final (OT) |
| April 1, 2022 | W | Orlando Solar Bears 3 at South Carolina Stingrays 4 | Final (OT) |
| April 2, 2022 | W | South Carolina Stingrays 7 at Orlando Solar Bears 3 | Final |
| April 6, 2022 | W | Jacksonville Icemen 2 at South Carolina Stingrays 3 | Final |
| April 8, 2022 | L | Florida Everblades 5 at South Carolina Stingrays 1 | Final |
| April 9, 2022 | W | Florida Everblades 3 at South Carolina Stingrays 6 | Final |
| April 13, 2022 | W | South Carolina Stingrays 5 at Norfolk Admirals 4 | Final (OT) |
| April 15, 2022 | L | South Carolina Stingrays 2 at Norfolk Admirals 4 | Final |
South Carolina Stingrays Schedule
