| | | |
| March 8, 2025 | W | Hartford Athletic 0 at Lexington Sporting Club 2 | Final |
| March 15, 2025 | T | Lexington Sporting Club 2 at Orange County SC 2 | Final |
| March 22, 2025 | T | Indy Eleven 1 at Lexington Sporting Club 1 | Final |
| March 29, 2025 | L | San Antonio FC 3 at Lexington Sporting Club 2 | Final |
| April 5, 2025 | L | Lexington Sporting Club 1 at El Paso Locomotive FC 2 | Final |
| April 12, 2025 | T | Las Vegas Lights FC 0 at Lexington Sporting Club 0 | Final |
| April 19, 2025 | T | Monterey Bay FC 0 at Lexington Sporting Club 0 | Final |
| April 26, 2025 | L | Loudoun United FC 1 at Lexington Sporting Club 0 (Jagermeister Cup) | Final |
| May 1, 2025 | L | Lexington Sporting Club 0 at Louisville City FC 2 | Final |
| May 10, 2025 | L | Lexington Sporting Club 1 at Loudoun United FC 5 | Final |
| May 18, 2025 | L | FC Tulsa 2 at Lexington Sporting Club 0 | Final |
| May 24, 2025 | T | Tampa Bay Rowdies 1 at Lexington Sporting Club 1 | Final |
| May 31, 2025 | T | Lexington Sporting Club 2 at Charlotte Independence 2 (Jagermeister Cup) | Final |
| June 7, 2025 | L | Lexington Sporting Club 1 at Monterey Bay FC 2 | Final |
| June 14, 2025 | W | New Mexico United 1 at Lexington Sporting Club 2 | Final |
| June 20, 2025 | W | Colorado Springs Switchbacks FC 1 at Lexington Sporting Club 2 | Final |
| June 28, 2025 | W | Lexington Sporting Club 3 at Richmond Kickers 0 (Jagermeister Cup) | Final |
| July 4, 2025 | W | Lexington Sporting Club 1 at Phoenix Rising FC 0 | Final |
| July 12, 2025 | T | Lexington Sporting Club 1 at Miami FC 1 | Final |
| July 19, 2025 | | Lexington Sporting Club at Sacramento Republic FC | 11:00 p.m. |
| July 26, 2025 | | Louisville City FC at Lexington Sporting Club (Jagermeister Cup) | 7:00 p.m. |
| August 1, 2025 | | Lexington Sporting Club at Colorado Springs Switchbacks FC | 9:00 p.m. |
| August 9, 2025 | | Phoenix Rising FC at Lexington Sporting Club | 6:00 p.m. |
| August 16, 2025 | | Lexington Sporting Club at San Antonio FC | 9:00 p.m. |
| August 23, 2025 | | Oakland Roots at Lexington Sporting Club | 7:00 p.m. |
| August 30, 2025 | | Lexington Sporting Club at Las Vegas Lights FC | 10:30 p.m. |
| September 5, 2025 | | North Carolina FC at Lexington Sporting Club | 7:00 p.m. |
| September 12, 2025 | | Orange County SC at Lexington Sporting Club | 7:00 p.m. |
| September 20, 2025 | | Lexington Sporting Club at Detroit City FC | 7:00 p.m. |
| September 28, 2025 | | Lexington Sporting Club at New Mexico United | 6:00 p.m. |
| October 4, 2025 | | Lexington Sporting Club at FC Tulsa | 8:00 p.m. |
| October 11, 2025 | | El Paso Locomotive FC at Lexington Sporting Club | 7:00 p.m. |
| October 17, 2025 | | Sacramento Republic FC at Lexington Sporting Club | 7:00 p.m. |
| October 25, 2025 | | Lexington Sporting Club at Oakland Roots | 10:00 p.m. |
Lexington Sporting Club Schedule
