| | | |
| May 19, 2025 | W | Calgary Stampeders 26 at B.C. Lions 16 (Preseason) | Final |
| May 24, 2025 | W | Edmonton Elks 4 at Calgary Stampeders 31 (Preseason) | Final |
| June 7, 2025 | W | Hamilton Tiger-Cats 26 at Calgary Stampeders 38 | Final |
| June 14, 2025 | W | Calgary Stampeders 29 at Toronto Argonauts 19 | Final |
| June 21, 2025 | L | Ottawa RedBlacks 20 at Calgary Stampeders 12 | Final |
| July 3, 2025 | W | Winnipeg Blue Bombers 16 at Calgary Stampeders 37 | Final |
| July 12, 2025 | W | Calgary Stampeders 24 at Saskatchewan Roughriders 10 | Final |
| July 18, 2025 | W | Calgary Stampeders 41 at Winnipeg Blue Bombers 20 | Final |
| July 24, 2025 | L | Montreal Alouettes 23 at Calgary Stampeders 21 | Final |
| July 31, 2025 | L | Calgary Stampeders 11 at Ottawa RedBlacks 31 | Final |
| August 9, 2025 | W | Winnipeg Blue Bombers 27 at Calgary Stampeders 28 | Final |
| August 23, 2025 | | Saskatchewan Roughriders at Calgary Stampeders | 7:00 p.m. |
| September 1, 2025 | | Edmonton Elks at Calgary Stampeders | 6:00 p.m. |
| September 6, 2025 | | Calgary Stampeders at Edmonton Elks | 7:00 p.m. |
| September 19, 2025 | | B.C. Lions at Calgary Stampeders | 9:30 p.m. |
| September 26, 2025 | | Calgary Stampeders at Montreal Alouettes | 7:00 p.m. |
| October 4, 2025 | | Calgary Stampeders at B.C. Lions | 7:00 p.m. |
| October 11, 2025 | | Calgary Stampeders at Hamilton Tiger-Cats | 3:00 p.m. |
| October 18, 2025 | | Toronto Argonauts at Calgary Stampeders | 7:00 p.m. |
| October 24, 2025 | | Calgary Stampeders at Edmonton Elks | 9:30 p.m. |
Calgary Stampeders Schedule
