| | | |
| May 19, 2025 | L | Calgary Stampeders 26 at B.C. Lions 16 (Preseason) | Final |
| May 30, 2025 | L | B.C. Lions 19 at Edmonton Elks 20 (Preseason) | Final |
| June 7, 2025 | W | Edmonton Elks 14 at B.C. Lions 31 | Final |
| June 12, 2025 | L | B.C. Lions 20 at Winnipeg Blue Bombers 34 | Final |
| June 21, 2025 | L | Winnipeg Blue Bombers 27 at B.C. Lions 14 | Final |
| June 28, 2025 | L | B.C. Lions 18 at Saskatchewan Roughriders 37 | Final |
| July 5, 2025 | W | B.C. Lions 21 at Montreal Alouettes 20 | Final |
| July 13, 2025 | W | B.C. Lions 32 at Edmonton Elks 14 | Final |
| July 19, 2025 | L | Saskatchewan Roughriders 33 at B.C. Lions 27 | Final |
| July 27, 2025 | | Hamilton Tiger-Cats at B.C. Lions | 7:00 p.m. |
| August 7, 2025 | | B.C. Lions at Hamilton Tiger-Cats | 7:30 p.m. |
| August 16, 2025 | | Montreal Alouettes at B.C. Lions | 7:00 p.m. |
| August 23, 2025 | | B.C. Lions at Toronto Argonauts | 3:00 p.m. |
| September 5, 2025 | | B.C. Lions at Ottawa RedBlacks | 7:30 p.m. |
| September 12, 2025 | | Ottawa RedBlacks at B.C. Lions | 10:00 p.m. |
| September 19, 2025 | | B.C. Lions at Calgary Stampeders | 9:30 p.m. |
| September 26, 2025 | | Toronto Argonauts at B.C. Lions | 10:00 p.m. |
| October 4, 2025 | | Calgary Stampeders at B.C. Lions | 7:00 p.m. |
| October 17, 2025 | | Edmonton Elks at B.C. Lions | 10:30 p.m. |
| October 25, 2025 | | B.C. Lions at Saskatchewan Roughriders | 7:00 p.m. |
B.C. Lions Schedule
