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| November 29, 2025 | | San Diego Seals at Ottawa Black Bears | 7:00 p.m. |
| December 14, 2025 | | Rochester Knighthawks at San Diego Seals | 6:00 p.m. |
| January 3, 2026 | | Calgary Roughnecks at San Diego Seals | 10:00 p.m. |
| January 9, 2026 | | Toronto Rock at San Diego Seals | 10:30 p.m. |
| January 16, 2026 | | San Diego Seals at Vancouver Warriors | 10:00 p.m. |
| January 23, 2026 | | San Diego Seals at Philadelphia Wings | 7:00 p.m. |
| January 30, 2026 | | Philadelphia Wings at San Diego Seals | 10:30 p.m. |
| February 7, 2026 | | Saskatchewan Rush at San Diego Seals | 10:00 p.m. |
| February 14, 2026 | | San Diego Seals at Oshawa FireWolves | 7:00 p.m. |
| February 21, 2026 | | Halifax Thunderbirds at San Diego Seals | 10:00 p.m. |
| February 27, 2026 | | San Diego Seals at Colorado Mammoth | 9:00 p.m. |
| March 1, 2026 | | Vancouver Warriors at San Diego Seals | 6:00 p.m. |
| March 14, 2026 | | San Diego Seals at Saskatchewan Rush | 9:00 p.m. |
| March 21, 2026 | | Buffalo Bandits at San Diego Seals | 10:00 p.m. |
| April 4, 2026 | | San Diego Seals at Toronto Rock | 7:00 p.m. |
| April 12, 2026 | | San Diego Seals at Georgia Swarm | 4:00 p.m. |
| April 17, 2026 | | Las Vegas Desert Dogs at San Diego Seals | 10:30 p.m. |
| April 18, 2026 | | San Diego Seals at Las Vegas Desert Dogs | 10:00 p.m. |
San Diego Seals Schedule
