| | | |
| October 10, 2025 | W | Toronto Marlies 3 at Rochester Americans 4 | Final |
| October 11, 2025 | L | Rochester Americans 1 at Toronto Marlies 4 | Final |
| October 17, 2025 | W | Rochester Americans 7 at Utica Comets 4 | Final |
| October 18, 2025 | L | Rochester Americans 0 at Syracuse Crunch 3 | Final |
| October 22, 2025 | W | Syracuse Crunch 2 at Rochester Americans 4 | Final |
| October 24, 2025 | W | Laval Rocket 0 at Rochester Americans 4 | Final |
| October 25, 2025 | W | Rochester Americans 4 at Cleveland Monsters 3 | Final (OT) |
| October 29, 2025 | W | Rochester Americans 4 at Belleville Senators 1 | Final |
| October 31, 2025 | W | Rochester Americans 2 at Laval Rocket 1 | Final |
| November 1, 2025 | L | Rochester Americans 2 at Laval Rocket 5 | Final |
| November 5, 2025 | L | Syracuse Crunch 5 at Rochester Americans 3 | Final |
| November 7, 2025 | W | Wilkes-Barre/Scranton Penguins 4 at Rochester Americans 6 | Final |
| November 9, 2025 | L | Rochester Americans 1 at Hershey Bears 2 | Final |
| November 12, 2025 | L | Belleville Senators 6 at Rochester Americans 4 | Final |
| November 14, 2025 | W | Rochester Americans 4 at Hartford Wolf Pack 3 | Final (OT) |
| November 15, 2025 | W | Rochester Americans 5 at Bridgeport Islanders 3 | Final |
| November 19, 2025 | L | Rochester Americans 2 at Lehigh Valley Phantoms 4 | Final |
| November 21, 2025 | L | Bridgeport Islanders 5 at Rochester Americans 4 | Final |
| November 22, 2025 | W | Rochester Americans 4 at Utica Comets 3 | Final |
| November 26, 2025 | L | Cleveland Monsters 3 at Rochester Americans 1 | Final |
| November 28, 2025 | W | Syracuse Crunch 3 at Rochester Americans 4 | Final |
| December 3, 2025 | L | Utica Comets 4 at Rochester Americans 3 | Final (OT) |
| December 5, 2025 | W | Rochester Americans 6 at Charlotte Checkers 3 | Final |
| December 6, 2025 | L | Rochester Americans 3 at Charlotte Checkers 4 | Final (OT) |
| December 10, 2025 | W | Rochester Americans 6 at Belleville Senators 1 | Final |
| December 13, 2025 | L | Lehigh Valley Phantoms 2 at Rochester Americans 1 | Final (SO) |
| December 17, 2025 | L | Utica Comets 3 at Rochester Americans 2 | Final |
| December 19, 2025 | W | Belleville Senators 2 at Rochester Americans 3 | Final (OT) |
| December 27, 2025 | L | Cleveland Monsters 4 at Rochester Americans 3 | Final (OT) |
| December 29, 2025 | W | Rochester Americans 4 at Cleveland Monsters 3 | Final (OT) |
| January 3, 2026 | L | Rochester Americans 4 at Toronto Marlies 6 | Final |
| January 7, 2026 | W | Rochester Americans 3 at Syracuse Crunch 2 | Final |
| January 9, 2026 | L | Laval Rocket 3 at Rochester Americans 2 | Final |
| January 11, 2026 | W | Rochester Americans 6 at Belleville Senators 5 | Final (OT) |
| January 14, 2026 | W | Syracuse Crunch 0 at Rochester Americans 3 | Final |
| January 16, 2026 | L | Rochester Americans 4 at Belleville Senators 5 | Final (OT) |
| January 17, 2026 | L | Rochester Americans 0 at Utica Comets 3 | Final |
| January 19, 2026 | L | Rochester Americans 2 at Syracuse Crunch 3 | Final (SO) |
| January 23, 2026 | W | Utica Comets 0 at Rochester Americans 3 | Final |
| January 24, 2026 | L | Cleveland Monsters 2 at Rochester Americans 1 | Final |
| January 28, 2026 | L | Hershey Bears 3 at Rochester Americans 1 | Final |
| January 30, 2026 | W | Hershey Bears 1 at Rochester Americans 3 | Final |
| February 4, 2026 | L | Belleville Senators 3 at Rochester Americans 1 | Final |
| February 6, 2026 | W | Springfield Thunderbirds 0 at Rochester Americans 4 | Final |
| February 7, 2026 | W | Rochester Americans 5 at Utica Comets 1 | Final |
| February 14, 2026 | W | Rochester Americans 4 at Utica Comets 1 | Final |
| February 15, 2026 | L | Utica Comets 7 at Rochester Americans 4 | Final |
| February 18, 2026 | L | Charlotte Checkers 3 at Rochester Americans 2 | Final (SO) |
| February 20, 2026 | L | Laval Rocket 3 at Rochester Americans 2 | Final (OT) |
| February 25, 2026 | L | Rochester Americans 2 at Cleveland Monsters 4 | Final |
| February 27, 2026 | L | Laval Rocket 9 at Rochester Americans 3 | Final |
| March 1, 2026 | L | Rochester Americans 1 at Syracuse Crunch 3 | Final |
| March 6, 2026 | L | Rochester Americans 2 at Laval Rocket 4 | Final |
| March 7, 2026 | L | Rochester Americans 3 at Laval Rocket 4 | Final (SO) |
| March 11, 2026 | L | Utica Comets 4 at Rochester Americans 1 | Final |
| March 13, 2026 | W | Toronto Marlies 3 at Rochester Americans 4 | Final (OT) |
| March 14, 2026 | L | Rochester Americans 0 at Toronto Marlies 3 | Final |
| March 20, 2026 | L | Syracuse Crunch 5 at Rochester Americans 3 | Final |
| March 22, 2026 | W | Hartford Wolf Pack 3 at Rochester Americans 6 | Final |
| March 27, 2026 | W | Toronto Marlies 2 at Rochester Americans 5 | Final |
| March 28, 2026 | L | Rochester Americans 3 at Syracuse Crunch 5 | Final |
| March 29, 2026 | W | Syracuse Crunch 2 at Rochester Americans 3 | Final (SO) |
| April 1, 2026 | | Charlotte Checkers at Rochester Americans | 7:05 p.m. |
| April 3, 2026 | | Belleville Senators at Rochester Americans | 7:05 p.m. |
| April 4, 2026 | | Providence Bruins at Rochester Americans | 5:05 p.m. |
| April 6, 2026 | | Rochester Americans at Cleveland Monsters | 7:00 p.m. |
| April 8, 2026 | | Rochester Americans at Syracuse Crunch | 7:00 p.m. |
| April 10, 2026 | | Rochester Americans at Springfield Thunderbirds | 7:05 p.m. |
| April 11, 2026 | | Rochester Americans at Providence Bruins | 7:05 p.m. |
| April 17, 2026 | | Cleveland Monsters at Rochester Americans | 7:05 p.m. |
| April 18, 2026 | | Rochester Americans at Wilkes-Barre/Scranton Penguins | 6:05 p.m. |
| April 19, 2026 | | Rochester Americans at Hershey Bears | 3:00 p.m. |
Rochester Americans Schedule
