| | | |
| March 14, 2025 | W | Chicago Stars FC 0 at Orlando Pride 6 | Final |
| March 23, 2025 | W | Orlando Pride 2 at NJ/NY Gotham FC 0 | Final |
| March 29, 2025 | W | San Diego Wave FC 1 at Orlando Pride 2 | Final |
| April 12, 2025 | W | Orlando Pride 1 at Seattle Reign FC 0 | Final |
| April 19, 2025 | L | Washington Spirit 1 at Orlando Pride 0 | Final |
| April 25, 2025 | W | Angel City FC 2 at Orlando Pride 3 | Final |
| May 3, 2025 | L | Orlando Pride 0 at Portland Thorns FC 1 | Final |
| May 10, 2025 | T | Orlando Pride 1 at North Carolina Courage 1 | Final |
| May 16, 2025 | L | Kansas City Current 1 at Orlando Pride 0 | Final |
| May 23, 2025 | W | Orlando Pride 3 at Utah Royals FC 1 | Final |
| June 7, 2025 | W | Houston Dash 0 at Orlando Pride 1 | Final |
| June 13, 2025 | W | Orlando Pride 1 at Bay FC 0 | Final |
| June 20, 2025 | L | Orlando Pride 0 at Racing Louisville FC 2 | Final |
| August 3, 2025 | T | Utah Royals FC 1 at Orlando Pride 1 | Final |
| August 9, 2025 | T | Racing Louisville FC 1 at Orlando Pride 1 | Final |
| August 16, 2025 | T | Orlando Pride 0 at Kansas City Current 0 | Final |
| August 21, 2025 | L | Orlando Pride 0 at Angel City FC 1 | Final |
| August 29, 2025 | L | NJ/NY Gotham FC 2 at Orlando Pride 0 | Final |
| September 7, 2025 | L | Orlando Pride 2 at Chicago Stars FC 5 | Final |
| September 13, 2025 | T | Bay FC 1 at Orlando Pride 1 | Final |
| September 19, 2025 | L | North Carolina Courage 1 at Orlando Pride 0 | Final |
| September 26, 2025 | W | Orlando Pride 2 at San Diego Wave FC 1 | Final |
| October 3, 2025 | T | Orlando Pride 1 at Houston Dash 1 | Final |
| October 10, 2025 | W | Portland Thorns FC 0 at Orlando Pride 1 | Final |
| October 18, 2025 | W | Orlando Pride 3 at Washington Spirit 2 | Final |
| November 2, 2025 | T | Seattle Reign FC 1 at Orlando Pride 1 | Final |
| November 7, 2025 | W | Seattle Reign FC 0 at Orlando Pride 2 (Playoff) | Final |
Orlando Pride Schedule
