| | | |
| March 21, 2025 | L | Jacksonville Sharks 46 at Massachusetts Pirates 25 | Final |
| March 28, 2025 | L | Quad City Steamwheelers 37 at Massachusetts Pirates 33 | Final |
| April 12, 2025 | W | Fishers Freight 47 at Massachusetts Pirates 50 | Final |
| April 19, 2025 | W | Massachusetts Pirates 42 at Jacksonville Sharks 35 | Final |
| April 27, 2025 | L | Green Bay Blizzard 47 at Massachusetts Pirates 35 | Final |
| May 10, 2025 | L | Massachusetts Pirates 26 at Tucson Sugar Skulls 47 | Final |
| May 18, 2025 | L | Massachusetts Pirates 24 at Northern Arizona Wranglers 33 | Final |
| May 29, 2025 | W | Jacksonville Sharks 29 at Massachusetts Pirates 43 | Final |
| June 7, 2025 | W | Massachusetts Pirates 40 at Fishers Freight 23 | Final |
| June 14, 2025 | W | Massachusetts Pirates 66 at Iowa Barnstormers 35 | Final |
| June 21, 2025 | W | Tulsa Oilers 37 at Massachusetts Pirates 58 | Final |
| June 28, 2025 | L | Massachusetts Pirates 35 at Quad City Steamwheelers 56 | Final |
| July 3, 2025 | W | Iowa Barnstormers 31 at Massachusetts Pirates 54 | Final |
| July 12, 2025 | L | Massachusetts Pirates 28 at Tulsa Oilers 35 | Final (OT) |
| July 18, 2025 | L | Massachusetts Pirates 27 at Green Bay Blizzard 56 | Final |
| July 25, 2025 | L | Bay Area Panthers 45 at Massachusetts Pirates 30 | Final |
Massachusetts Pirates Schedule
