| | | |
| March 6, 2026 | L | Louisville City FC 2 at Lexington SC 1 | Final |
| March 14, 2026 | T | Sacramento Republic FC 0 at Lexington SC 0 | Final |
| March 25, 2026 | W | Brooklyn FC 0 at Lexington SC 3 | Final |
| March 29, 2026 | L | Lexington SC 0 at San Antonio FC 2 | Final |
| April 4, 2026 | T | Lexington SC 1 at Colorado Springs Switchbacks FC 1 | Final |
| April 11, 2026 | L | Rhode Island FC 3 at Lexington SC 1 | Final |
| April 18, 2026 | T | Lexington SC 0 at Orange County SC 0 | Final |
| April 25, 2026 | W | Forward Madison FC 2 at Lexington SC 4 (USL Cup) | Final |
| May 2, 2026 | L | Lexington SC 1 at Las Vegas Lights FC 2 | Final |
| May 8, 2026 | W | Monterey Bay FC 1 at Lexington SC 3 | Final |
| May 23, 2026 | L | Lexington SC 1 at Indy Eleven 3 | Final |
| May 30, 2026 | W | Lexington SC 4 at El Paso Locomotive FC 1 | Final |
| June 6, 2026 | T | Lexington SC 1 at Detroit City FC 1 (USL Cup) | Final (PK 3-1) |
| June 13, 2026 | W | San Antonio FC 0 at Lexington SC 2 | Final |
| June 20, 2026 | T | Indy Eleven 0 at Lexington SC 0 (USL Cup) | Final (PK 7-6) |
| July 4, 2026 | W | Lexington SC 4 at Tampa Bay Rowdies 1 | Final |
| July 11, 2026 | L | Lexington SC 2 at Louisville City FC 4 (USL Cup) | Final |
| July 15, 2026 | L | New Mexico United 4 at Lexington SC 1 | Final |
| July 22, 2026 | W | Oakland Roots SC 0 at Lexington SC 2 | Final |
| July 25, 2026 | T | Lexington SC 0 at FC Tulsa 0 | Final |
| August 1, 2026 | W | Monterey Bay FC 2 at Lexington SC 3 | Final |
| August 8, 2026 | W | Phoenix Rising FC 0 at Lexington SC 1 | Final |
| August 15, 2026 | L | Lexington SC 0 at Sacramento Republic FC 1 | Final |
| August 22, 2026 | W | Las Vegas Lights FC 0 at Lexington SC 2 | Final |
| August 26, 2026 | L | Lexington SC 1 at New Mexico United 2 | Final |
| August 29, 2026 | L | Colorado Springs Switchbacks FC 1 at Lexington SC 0 | Final |
| September 5, 2026 | L | Lexington SC 2 at Sporting Club Jacksonville 3 | Final |
| September 12, 2026 | W | Lexington SC 4 at Oakland Roots SC 1 | Final |
| September 19, 2026 | W | Orange County SC 0 at Lexington SC 6 | Final |
| September 26, 2026 | W | Lexington SC 3 at Monterey Bay FC 2 | Final |
| October 3, 2026 | W | El Paso Locomotive FC 1 at Lexington SC 3 | Final |
| October 9, 2026 | | FC Tulsa at Lexington SC | 7:30 p.m. |
| October 17, 2026 | | Lexington SC at Las Vegas Lights FC | 10:30 p.m. |
| October 24, 2026 | | Lexington SC at Phoenix Rising FC | 10:00 p.m. |
Lexington SC Schedule
