| | | |
| March 6, 2026 | L | Louisville City FC 2 at Lexington SC 1 | Final |
| March 14, 2026 | T | Sacramento Republic FC 0 at Lexington SC 0 | Final |
| March 25, 2026 | W | Brooklyn FC 0 at Lexington SC 3 | Final |
| March 29, 2026 | L | Lexington SC 0 at San Antonio FC 2 | Final |
| April 4, 2026 | T | Lexington SC 1 at Colorado Springs Switchbacks FC 1 | Final |
| April 11, 2026 | L | Rhode Island FC 3 at Lexington SC 1 | Final |
| April 18, 2026 | T | Lexington SC 0 at Orange County SC 0 | Final |
| April 25, 2026 | W | Forward Madison FC 2 at Lexington SC 4 (USL Cup) | Final |
| May 2, 2026 | L | Lexington SC 1 at Las Vegas Lights FC 2 | Final |
| May 8, 2026 | W | Monterey Bay FC 1 at Lexington SC 3 | Final |
| May 23, 2026 | | Lexington SC at Indy Eleven | 7:00 p.m. |
| May 30, 2026 | | Lexington SC at El Paso Locomotive FC | 9:00 p.m. |
| June 6, 2026 | | Lexington SC at Detroit City FC | 7:00 p.m. |
| June 13, 2026 | | San Antonio FC at Lexington SC | 7:00 p.m. |
| June 20, 2026 | | Indy Eleven at Lexington SC | 7:00 p.m. |
| July 4, 2026 | | Lexington SC at Tampa Bay Rowdies | 6:00 p.m. |
| July 11, 2026 | | Lexington SC at Louisville City FC | 8:00 p.m. |
| July 15, 2026 | | New Mexico United at Lexington SC | 7:00 p.m. |
| July 22, 2026 | | Oakland Roots SC at Lexington SC | 7:00 p.m. |
| July 25, 2026 | | Lexington SC at FC Tulsa | 8:30 p.m. |
| August 1, 2026 | | Monterey Bay FC at Lexington SC | 7:00 p.m. |
| August 8, 2026 | | Phoenix Rising FC at Lexington SC | 7:00 p.m. |
| August 15, 2026 | | Lexington SC at Sacramento Republic FC | 11:00 p.m. |
| August 22, 2026 | | Las Vegas Lights FC at Lexington SC | 7:00 p.m. |
| August 26, 2026 | | Lexington SC at New Mexico United | 9:30 p.m. |
| August 29, 2026 | | Colorado Springs Switchbacks FC at Lexington SC | 7:00 p.m. |
| September 5, 2026 | | Lexington SC at Sporting Club Jacksonville | 7:00 p.m. |
| September 12, 2026 | | Lexington SC at Oakland Roots SC | 10:00 p.m. |
| September 19, 2026 | | Orange County SC at Lexington SC | 7:00 p.m. |
| September 26, 2026 | | Lexington SC at Monterey Bay FC | 10:00 p.m. |
| October 3, 2026 | | El Paso Locomotive FC at Lexington SC | 7:00 p.m. |
| October 9, 2026 | | FC Tulsa at Lexington SC | 7:30 p.m. |
| October 17, 2026 | | Lexington SC at Las Vegas Lights FC | 10:30 p.m. |
| October 24, 2026 | | Lexington SC at Phoenix Rising FC | 10:00 p.m. |
Lexington SC Schedule
