| | | |
| December 13, 2025 | L | Las Vegas Desert Dogs 9 at Vancouver Warriors 15 | Final |
| December 20, 2025 | W | Ottawa Black Bears 9 at Las Vegas Desert Dogs 10 | Final |
| December 27, 2025 | W | Las Vegas Desert Dogs 17 at Toronto Rock 11 | Final |
| January 3, 2026 | L | Las Vegas Desert Dogs 13 at Buffalo Bandits 15 | Final |
| January 9, 2026 | L | Saskatchewan Rush 21 at Las Vegas Desert Dogs 15 | Final |
| January 17, 2026 | W | Philadelphia Wings 7 at Las Vegas Desert Dogs 10 | Final |
| January 31, 2026 | W | Oshawa FireWolves 13 at Las Vegas Desert Dogs 16 | Final |
| February 7, 2026 | L | Las Vegas Desert Dogs 9 at Georgia Swarm 12 | Final |
| February 13, 2026 | L | Colorado Mammoth 13 at Las Vegas Desert Dogs 12 | Final |
| February 27, 2026 | L | Vancouver Warriors 14 at Las Vegas Desert Dogs 10 | Final |
| March 7, 2026 | L | Las Vegas Desert Dogs 11 at Halifax Thunderbirds 13 | Final |
| March 15, 2026 | W | Rochester Knighthawks 10 at Las Vegas Desert Dogs 17 | Final |
| March 21, 2026 | W | Las Vegas Desert Dogs 17 at Rochester Knighthawks 13 | Final |
| March 28, 2026 | W | Calgary Roughnecks 9 at Las Vegas Desert Dogs 10 | Final (OT) |
| April 3, 2026 | L | Las Vegas Desert Dogs 8 at Colorado Mammoth 13 | Final |
| April 11, 2026 | L | Las Vegas Desert Dogs 5 at Philadelphia Wings 11 | Final |
| April 17, 2026 | L | Las Vegas Desert Dogs 12 at San Diego Seals 14 | Final |
| April 18, 2026 | W | San Diego Seals 16 at Las Vegas Desert Dogs 18 | Final |
Las Vegas Desert Dogs Schedule
