| | | |
| November 30, 2024 | L | Las Vegas Desert Dogs 12 at Rochester Knighthawks 14 | Final |
| December 6, 2024 | L | Colorado Mammoth 15 at Las Vegas Desert Dogs 9 | Final |
| December 14, 2024 | L | Las Vegas Desert Dogs 10 at Philadelphia Wings 19 | Final |
| December 20, 2024 | L | Philadelphia Wings 15 at Las Vegas Desert Dogs 9 | Final |
| January 4, 2025 | W | Las Vegas Desert Dogs 12 at Albany FireWolves 11 | Final |
| January 11, 2025 | L | Las Vegas Desert Dogs 9 at Saskatchewan Rush 15 | Final |
| January 18, 2025 | W | San Diego Seals 10 at Las Vegas Desert Dogs 12 | Final |
| February 1, 2025 | L | Georgia Swarm 16 at Las Vegas Desert Dogs 14 | Final |
| February 14, 2025 | L | Vancouver Warriors 12 at Las Vegas Desert Dogs 8 | Final |
| February 16, 2025 | L | Las Vegas Desert Dogs 8 at Calgary Roughnecks 21 | Final |
| February 21, 2025 | W | Las Vegas Desert Dogs 14 at Colorado Mammoth 7 | Final |
| March 1, 2025 | L | Halifax Thunderbirds 9 at Las Vegas Desert Dogs 5 | Final |
| March 7, 2025 | L | Rochester Knighthawks 21 at Las Vegas Desert Dogs 13 | Final |
| March 16, 2025 | L | Las Vegas Desert Dogs 11 at San Diego Seals 20 | Final |
| March 21, 2025 | L | Las Vegas Desert Dogs 10 at Buffalo Bandits 13 | Final |
| April 6, 2025 | W | Toronto Rock 13 at Las Vegas Desert Dogs 14 | Final |
| April 12, 2025 | L | Las Vegas Desert Dogs 10 at Ottawa Black Bears 13 | Final |
| April 18, 2025 | L | Calgary Roughnecks 12 at Las Vegas Desert Dogs 9 | Final |
Las Vegas Desert Dogs Schedule
