| | | |
| March 8, 2025 | W | Oakland Roots 2 at Orange County SC 4 | Final |
| March 15, 2025 | T | Lexington Sporting Club 2 at Orange County SC 2 | Final |
| March 22, 2025 | L | Monterey Bay FC 3 at Orange County SC 0 | Final |
| April 5, 2025 | L | Orange County SC 0 at Las Vegas Lights FC 1 | Final |
| April 12, 2025 | W | Sacramento Republic FC 1 at Orange County SC 2 | Final |
| April 19, 2025 | L | Orange County SC 0 at Oakland Roots 2 | Final |
| April 26, 2025 | L | Las Vegas Lights FC 3 at Orange County SC 1 (Jagermeister Cup) | Final |
| May 3, 2025 | W | FC Tulsa 1 at Orange County SC 2 | Final |
| May 9, 2025 | L | Orange County SC 0 at North Carolina FC 1 | Final |
| May 17, 2025 | L | New Mexico United 3 at Orange County SC 0 | Final |
| May 24, 2025 | W | Colorado Springs Switchbacks FC 1 at Orange County SC 3 | Final |
| May 31, 2025 | L | Orange County SC 2 at Monterey Bay FC 3 | Final |
| June 7, 2025 | L | Orange County SC 1 at Phoenix Rising FC 3 | Final |
| June 14, 2025 | W | Orange County SC 3 at El Paso Locomotive FC 0 | Final |
| June 28, 2025 | W | Sacramento Republic FC 0 at Orange County SC 1 | Final |
| July 3, 2025 | T | Orange County SC 0 at Loudoun United FC 0 | Final |
| July 11, 2025 | L | Orange County SC 1 at Monterey Bay FC 2 | Final |
| July 19, 2025 | W | Las Vegas Lights FC 0 at Orange County SC 4 | Final |
| July 26, 2025 | W | Orange County SC 1 at Oakland Roots 0 (Jagermeister Cup) | Final |
| July 30, 2025 | W | Phoenix Rising FC 1 at Orange County SC 4 | Final |
| August 9, 2025 | T | Orange County SC 1 at Pittsburgh Riverhounds SC 1 | Final |
| August 16, 2025 | W | Orange County SC 1 at Colorado Springs Switchbacks FC 0 | Final |
| August 23, 2025 | L | Orange County SC 0 at FC Tulsa 1 | Final |
| August 30, 2025 | T | Birmingham Legion FC 4 at Orange County SC 4 | Final |
| September 6, 2025 | L | Orange County SC 1 at Detroit City FC 4 | Final |
| September 12, 2025 | T | Orange County SC 1 at Lexington Sporting Club 1 | Final |
| September 20, 2025 | | Orange County SC at San Antonio FC | 8:30 p.m. |
| September 27, 2025 | | Charleston Battery at Orange County SC | 10:00 p.m. |
| October 1, 2025 | | Orange County SC at Sacramento Republic FC | 10:15 p.m. |
| October 4, 2025 | | El Paso Locomotive FC at Orange County SC | 10:00 p.m. |
| October 11, 2025 | | Orange County SC at New Mexico United | 9:00 p.m. |
| October 15, 2025 | | San Antonio FC at Orange County SC | 10:00 p.m. |
| October 18, 2025 | | Louisville City FC at Orange County SC | 10:00 p.m. |
| October 25, 2025 | | Indy Eleven at Orange County SC | 10:00 p.m. |
Orange County SC Schedule
