| | | |
| March 8, 2025 | W | Tampa Bay Rowdies 0 at Las Vegas Lights FC 1 | Final |
| March 15, 2025 | L | New Mexico United 3 at Las Vegas Lights FC 2 | Final |
| March 29, 2025 | T | Las Vegas Lights FC 0 at Oakland Roots 0 | Final |
| April 5, 2025 | W | Orange County SC 0 at Las Vegas Lights FC 1 | Final |
| April 12, 2025 | T | Las Vegas Lights FC 0 at Lexington Sporting Club 0 | Final |
| April 19, 2025 | L | FC Tulsa 4 at Las Vegas Lights FC 1 | Final |
| April 26, 2025 | W | Las Vegas Lights FC 3 at Orange County SC 1 (Jagermeister Cup) | Final |
| April 30, 2025 | W | AV Alta FC 1 at Las Vegas Lights FC 2 (Jagermeister Cup) | Final |
| May 3, 2025 | W | Loudoun United FC 0 at Las Vegas Lights FC 1 | Final |
| May 10, 2025 | T | Colorado Springs Switchbacks FC 0 at Las Vegas Lights FC 0 | Final |
| May 17, 2025 | L | Las Vegas Lights FC 0 at Sacramento Republic FC 5 | Final |
| May 24, 2025 | L | El Paso Locomotive FC 2 at Las Vegas Lights FC 1 | Final |
| May 28, 2025 | L | Phoenix Rising FC 1 at Las Vegas Lights FC 0 | Final |
| May 31, 2025 | L | Las Vegas Lights FC 0 at Sacramento Republic FC 4 | Final |
| June 7, 2025 | L | Las Vegas Lights FC 0 at San Antonio FC 3 | Final |
| June 14, 2025 | W | Monterey Bay FC 0 at Las Vegas Lights FC 2 | Final |
| June 21, 2025 | | Las Vegas Lights FC at Indy Eleven | 7:00 p.m. |
| June 28, 2025 | | Spokane Velocity FC at Las Vegas Lights FC | 10:30 p.m. |
| July 4, 2025 | | Sacramento Republic FC at Las Vegas Lights FC | 10:30 p.m. |
| July 12, 2025 | | Las Vegas Lights FC at FC Tulsa | 8:30 p.m. |
| July 19, 2025 | | Las Vegas Lights FC at Orange County SC | 10:00 p.m. |
| August 2, 2025 | | Las Vegas Lights FC at El Paso Locomotive FC | 9:00 p.m. |
| August 9, 2025 | | San Antonio FC at Las Vegas Lights FC | 10:30 p.m. |
| August 16, 2025 | | Las Vegas Lights FC at New Mexico United | 9:00 p.m. |
| August 23, 2025 | | North Carolina FC at Las Vegas Lights FC | 10:30 p.m. |
| August 30, 2025 | | Lexington Sporting Club at Las Vegas Lights FC | 10:30 p.m. |
| September 5, 2025 | | Las Vegas Lights FC at Phoenix Rising FC | 10:30 p.m. |
| September 13, 2025 | | Miami FC at Las Vegas Lights FC | 10:30 p.m. |
| September 20, 2025 | | Las Vegas Lights FC at Louisville City FC | 7:30 p.m. |
| September 27, 2025 | | Las Vegas Lights FC at Pittsburgh Riverhounds SC | 7:00 p.m. |
| October 5, 2025 | | Las Vegas Lights FC at Rhode Island FC | 4:00 p.m. |
| October 11, 2025 | | Oakland Roots at Las Vegas Lights FC | 10:30 p.m. |
| October 18, 2025 | | Las Vegas Lights FC at Colorado Springs Switchbacks FC | 8:00 p.m. |
| October 25, 2025 | | Las Vegas Lights FC at Monterey Bay FC | 10:00 p.m. |
Las Vegas Lights FC Schedule
