| | | |
| March 9, 2025 | T | Vancouver Whitecaps FC 2 3 at LAFC2 3 | Final (PK 4-2) |
| March 14, 2025 | W | Ventura County FC 1 at LAFC2 3 | Final |
| April 6, 2025 | L | LAFC2 0 at Houston Dynamo 2 1 | Final |
| April 10, 2025 | W | Tacoma Defiance 2 at LAFC2 3 | Final |
| April 23, 2025 | T | LAFC2 1 at Real Monarchs 1 | Final (PK 7-6) |
| April 27, 2025 | L | LAFC2 1 at The Town FC 5 | Final |
| May 4, 2025 | W | Colorado Rapids 2 2 at LAFC2 3 | Final |
| May 9, 2025 | L | LAFC2 1 at Ventura County FC 2 | Final |
| May 14, 2025 | L | LAFC2 0 at Portland Timbers 2 3 | Final |
| May 23, 2025 | W | LAFC2 3 at Sporting Kansas City II 0 | Final |
| June 1, 2025 | L | The Town FC 2 at LAFC2 1 | Final |
| June 12, 2025 | L | LAFC2 0 at Vancouver Whitecaps FC 2 2 | Final |
| June 25, 2025 | W | Minnesota United FC 2 0 at LAFC2 1 | Final |
| June 29, 2025 | L | Tacoma Defiance 3 at LAFC2 2 | Final |
| July 4, 2025 | L | LAFC2 1 at Austin FC II 4 | Final |
| July 13, 2025 | W | Portland Timbers 2 0 at LAFC2 1 | Final |
| July 20, 2025 | T | LAFC2 3 at Ventura County FC 3 | Final (PK 3-1) |
| July 27, 2025 | | Sporting Kansas City II at LAFC2 | 10:00 p.m. |
| August 3, 2025 | | The Town FC at LAFC2 | 10:00 p.m. |
| August 10, 2025 | | LAFC2 at Tacoma Defiance | 11:00 p.m. |
| August 17, 2025 | | LAFC2 at Real Monarchs | 9:30 p.m. |
| August 21, 2025 | | Vancouver Whitecaps FC 2 at LAFC2 | 10:00 p.m. |
| August 24, 2025 | | LAFC2 at North Texas SC | 8:45 p.m. |
| August 29, 2025 | | Austin FC II at LAFC2 | 10:00 p.m. |
| September 14, 2025 | | LAFC2 at Portland Timbers 2 | 4:00 p.m. |
| September 19, 2025 | | Real Monarchs at LAFC2 | 10:00 p.m. |
| September 28, 2025 | | LAFC2 at St. Louis City SC 2 | 5:00 p.m. |
| October 5, 2025 | | North Texas SC at LAFC2 | 4:00 p.m. |
LAFC2 Schedule
