| | | |
| October 18, 2024 | W | Columbus River Dragons 1 at Monroe Moccasins 0 | Final (OT) |
| October 19, 2024 | W | Columbus River Dragons 2 at Monroe Moccasins 1 | Final |
| November 1, 2024 | W | Mississippi Sea Wolves 0 at Columbus River Dragons 5 | Final |
| November 2, 2024 | W | Mississippi Sea Wolves 0 at Columbus River Dragons 4 | Final |
| November 7, 2024 | W | Columbus River Dragons 2 at Baton Rouge Zydeco 1 | Final |
| November 8, 2024 | W | Columbus River Dragons 2 at Baton Rouge Zydeco 1 | Final |
| November 16, 2024 | L | Athens Rock Lobsters 6 at Columbus River Dragons 5 | Final |
| November 22, 2024 | L | Carolina Thunderbirds 6 at Columbus River Dragons 0 | Final |
| November 23, 2024 | L | Carolina Thunderbirds 3 at Columbus River Dragons 2 | Final (SO) |
| November 27, 2024 | L | Baton Rouge Zydeco 5 at Columbus River Dragons 4 | Final (SO) |
| November 29, 2024 | W | Columbus River Dragons 5 at Baton Rouge Zydeco 3 | Final |
| November 30, 2024 | W | Columbus River Dragons 3 at Mississippi Sea Wolves 1 | Final |
| December 1, 2024 | W | Columbus River Dragons 5 at Mississippi Sea Wolves 2 | Final |
| December 6, 2024 | W | Columbus River Dragons 5 at Mississippi Sea Wolves 2 | Final |
| December 7, 2024 | W | Mississippi Sea Wolves 1 at Columbus River Dragons 3 | Final |
| December 13, 2024 | L | Monroe Moccasins 7 at Columbus River Dragons 3 | Final |
| December 14, 2024 | W | Monroe Moccasins 3 at Columbus River Dragons 6 | Final |
| December 20, 2024 | W | Athens Rock Lobsters 1 at Columbus River Dragons 2 | Final (OT) |
| December 21, 2024 | W | Columbus River Dragons 4 at Athens Rock Lobsters 3 | Final (SO) |
| December 27, 2024 | W | Blue Ridge Bobcats 4 at Columbus River Dragons 7 | Final |
| December 28, 2024 | L | Blue Ridge Bobcats 2 at Columbus River Dragons 1 | Final |
| December 29, 2024 | W | Columbus River Dragons 4 at Mississippi Sea Wolves 0 | Final |
| January 3, 2025 | L | Columbus River Dragons 1 at Athens Rock Lobsters 5 | Final |
| January 4, 2025 | W | Columbus River Dragons 5 at Athens Rock Lobsters 2 | Final |
| January 10, 2025 | W | Carolina Thunderbirds 2 at Columbus River Dragons 5 | Final |
| January 11, 2025 | L | Carolina Thunderbirds 5 at Columbus River Dragons 3 | Final |
| January 17, 2025 | | Columbus River Dragons at HC Venom | Ppd. |
| January 24, 2025 | W | Athens Rock Lobsters 1 at Columbus River Dragons 4 | Final |
| January 25, 2025 | L | Athens Rock Lobsters 1 at Columbus River Dragons 0 | Final (SO) |
| January 31, 2025 | L | Columbus River Dragons 4 at Binghamton Black Bears 11 | Final |
| February 1, 2025 | L | Columbus River Dragons 1 at Binghamton Black Bears 5 | Final |
| February 5, 2025 | L | Columbus River Dragons 3 at Athens Rock Lobsters 6 | Final |
| February 7, 2025 | W | Mississippi Sea Wolves 4 at Columbus River Dragons 7 | Final |
| February 8, 2025 | W | Mississippi Sea Wolves 1 at Columbus River Dragons 9 | Final |
| February 12, 2025 | L | Columbus River Dragons 4 at Athens Rock Lobsters 6 | Final |
| February 14, 2025 | W | Blue Ridge Bobcats 1 at Columbus River Dragons 3 | Final |
| February 15, 2025 | W | Blue Ridge Bobcats 1 at Columbus River Dragons 4 | Final |
| February 19, 2025 | L | Columbus River Dragons 1 at Athens Rock Lobsters 6 | Final |
| February 21, 2025 | W | Monroe Moccasins 3 at Columbus River Dragons 6 | Final |
| February 28, 2025 | W | Columbus River Dragons 6 at Motor City Rockers 3 | Final |
| March 1, 2025 | W | Columbus River Dragons 7 at Motor City Rockers 6 | Final |
| March 7, 2025 | W | Columbus River Dragons 7 at Carolina Thunderbirds 6 | Final |
| March 8, 2025 | L | Columbus River Dragons 1 at Carolina Thunderbirds 4 | Final |
| March 14, 2025 | W | Monroe Moccasins 3 at Columbus River Dragons 6 | Final |
| March 15, 2025 | W | Monroe Moccasins 1 at Columbus River Dragons 5 | Final |
| March 21, 2025 | L | Columbus River Dragons 1 at Carolina Thunderbirds 3 | Final |
| March 22, 2025 | W | Columbus River Dragons 5 at Carolina Thunderbirds 2 | Final |
| March 28, 2025 | L | HC Venom 3 at Columbus River Dragons 2 | Final |
| March 29, 2025 | L | HC Venom 1 at Columbus River Dragons 0 | Final |
| March 30, 2025 | W | HC Venom 0 at Columbus River Dragons 3 | Final |
| April 3, 2025 | W | Columbus River Dragons 4 at Monroe Moccasins 3 | Final (SO) |
| April 4, 2025 | W | Columbus River Dragons 4 at Monroe Moccasins 2 | Final |
| April 5, 2025 | W | Columbus River Dragons 4 at Monroe Moccasins 2 | Final |
| April 11, 2025 | W | Athens Rock Lobsters 1 at Columbus River Dragons 3 | Final |
| April 12, 2025 | L | Athens Rock Lobsters 5 at Columbus River Dragons 2 | Final |
| April 16, 2025 | W | Athens Rock Lobsters 4 at Columbus River Dragons 7 (Playoff Gm. 1) | Final |
| April 18, 2025 | L | Columbus River Dragons 3 at Athens Rock Lobsters 5 (Playoff Gm. 2) | Final |
| April 19, 2025 | W | Columbus River Dragons 4 at Athens Rock Lobsters 2 (Playoff Gm. 3) | Final |
| April 23, 2025 | W | Carolina Thunderbirds 1 at Columbus River Dragons 4 (Playoff Gm. 1) | Final |
| April 25, 2025 | W | Columbus River Dragons 4 at Carolina Thunderbirds 1 (Playoff Gm. 2) | Final |
| April 26, 2025 | L | Columbus River Dragons 2 at Carolina Thunderbirds 3 (Playoff Gm. 3) | Final |
Columbus River Dragons Schedule
