| | | |
| October 10, 2025 | W | Columbus River Dragons 3 at Pee Dee IceCats 2 | Final (SO) |
| October 11, 2025 | L | Columbus River Dragons 5 at Pee Dee IceCats 7 | Final |
| October 17, 2025 | L | Columbus River Dragons 2 at Blue Ridge Bobcats 4 | Final |
| October 18, 2025 | L | Columbus River Dragons 5 at Blue Ridge Bobcats 6 | Final |
| October 31, 2025 | W | Columbus River Dragons 7 at Baton Rouge Zydeco 1 | Final |
| November 1, 2025 | W | Columbus River Dragons 4 at Baton Rouge Zydeco 3 | Final |
| November 7, 2025 | | Columbus River Dragons at Twin City Thunderbirds | 7:35 p.m. |
| November 8, 2025 | | Columbus River Dragons at Twin City Thunderbirds | 6:05 p.m. |
| November 14, 2025 | | Pee Dee IceCats at Columbus River Dragons | 7:35 p.m. |
| November 15, 2025 | | Biloxi Breakers at Columbus River Dragons | 7:05 p.m. |
| November 21, 2025 | | Biloxi Breakers at Columbus River Dragons | 7:35 p.m. |
| November 22, 2025 | | Biloxi Breakers at Columbus River Dragons | 7:05 p.m. |
| November 26, 2025 | | Columbus River Dragons at Biloxi Breakers | 8:05 p.m. |
| November 28, 2025 | | Columbus River Dragons at Pee Dee IceCats | 7:15 p.m. |
| November 29, 2025 | | Columbus River Dragons at Pee Dee IceCats | 7:15 p.m. |
| December 5, 2025 | | Athens Rock Lobsters at Columbus River Dragons | 7:35 p.m. |
| December 6, 2025 | | Athens Rock Lobsters at Columbus River Dragons | 7:05 p.m. |
| December 12, 2025 | | Columbus River Dragons at Twin City Thunderbirds | 7:35 p.m. |
| December 13, 2025 | | Columbus River Dragons at Twin City Thunderbirds | 6:05 p.m. |
| December 19, 2025 | | Athens Rock Lobsters at Columbus River Dragons | 7:35 p.m. |
| December 20, 2025 | | Athens Rock Lobsters at Columbus River Dragons | 7:05 p.m. |
| December 26, 2025 | | Twin City Thunderbirds at Columbus River Dragons | 7:35 p.m. |
| December 27, 2025 | | Twin City Thunderbirds at Columbus River Dragons | 7:05 p.m. |
| December 31, 2025 | | Columbus River Dragons at Athens Rock Lobsters | 7:05 p.m. |
| January 2, 2026 | | Columbus River Dragons at Monroe Moccasins | 8:05 p.m. |
| January 3, 2026 | | Columbus River Dragons at Monroe Moccasins | 8:05 p.m. |
| January 9, 2026 | | Blue Ridge Bobcats at Columbus River Dragons | 7:35 p.m. |
| January 10, 2026 | | Blue Ridge Bobcats at Columbus River Dragons | 7:05 p.m. |
| January 11, 2026 | | Columbus River Dragons at Athens Rock Lobsters | 4:05 p.m. |
| January 16, 2026 | | Columbus River Dragons at Indiana Sentinels | 7:30 p.m. |
| January 17, 2026 | | Columbus River Dragons at Indiana Sentinels | 7:30 p.m. |
| January 23, 2026 | | Baton Rouge Zydeco at Columbus River Dragons | 7:35 p.m. |
| January 24, 2026 | | Baton Rouge Zydeco at Columbus River Dragons | 7:05 p.m. |
| January 30, 2026 | | Biloxi Breakers at Columbus River Dragons | 7:35 p.m. |
| January 31, 2026 | | Biloxi Breakers at Columbus River Dragons | 7:05 p.m. |
| February 1, 2026 | | Columbus River Dragons at Athens Rock Lobsters | 4:05 p.m. |
| February 6, 2026 | | Columbus River Dragons at Biloxi Breakers | 8:05 p.m. |
| February 7, 2026 | | Pee Dee IceCats at Columbus River Dragons | 7:05 p.m. |
| February 13, 2026 | | Baton Rouge Zydeco at Columbus River Dragons | 7:35 p.m. |
| February 14, 2026 | | Baton Rouge Zydeco at Columbus River Dragons | 7:05 p.m. |
| February 18, 2026 | | Columbus River Dragons at Athens Rock Lobsters | 10:35 a.m. |
| February 20, 2026 | | Pee Dee IceCats at Columbus River Dragons | 7:35 p.m. |
| February 21, 2026 | | Pee Dee IceCats at Columbus River Dragons | 7:05 p.m. |
| February 27, 2026 | | Biloxi Breakers at Columbus River Dragons | 7:35 p.m. |
| February 28, 2026 | | Columbus River Dragons at Biloxi Breakers | 8:05 p.m. |
| March 6, 2026 | | Monroe Moccasins at Columbus River Dragons | 7:35 p.m. |
| March 7, 2026 | | Monroe Moccasins at Columbus River Dragons | 7:05 p.m. |
| March 13, 2026 | | Columbus River Dragons at Pee Dee IceCats | 7:15 p.m. |
| March 14, 2026 | | Columbus River Dragons at Pee Dee IceCats | 7:15 p.m. |
| March 15, 2026 | | Columbus River Dragons at Pee Dee IceCats | 3:15 p.m. |
| March 27, 2026 | | Monroe Moccasins at Columbus River Dragons | 7:35 p.m. |
| March 28, 2026 | | Monroe Moccasins at Columbus River Dragons | 7:05 p.m. |
| April 3, 2026 | | Columbus River Dragons at Monroe Moccasins | 8:05 p.m. |
| April 4, 2026 | | Columbus River Dragons at Monroe Moccasins | 8:05 p.m. |
| April 10, 2026 | | Pee Dee IceCats at Columbus River Dragons | 7:35 p.m. |
| April 11, 2026 | | Pee Dee IceCats at Columbus River Dragons | 7:05 p.m. |
Columbus River Dragons Schedule
