| | | |
| April 25, 2025 | L | Charleston Dirty Birds 1 at Lexington Legends 2 | Final |
| April 26, 2025 | L | Charleston Dirty Birds 5 at Lexington Legends 9 | Final |
| April 27, 2025 | L | Charleston Dirty Birds 3 at Lexington Legends 17 | Final |
| April 29, 2025 | W | Charleston Dirty Birds 6 at Southern Maryland Blue Crabs 3 | Final |
| April 30, 2025 | W | Charleston Dirty Birds 12 at Southern Maryland Blue Crabs 8 | Final |
| May 1, 2025 | L | Charleston Dirty Birds 1 at Southern Maryland Blue Crabs 3 | Final |
| May 2, 2025 | L | Southern Maryland Blue Crabs 7 at Charleston Dirty Birds 5 | Final |
| May 3, 2025 | | Southern Maryland Blue Crabs 1 at Charleston Dirty Birds 1 | Susp. |
| May 4, 2025 | L | Southern Maryland Blue Crabs 7 at Charleston Dirty Birds 2 | Final |
| May 6, 2025 | W | Lexington Legends 0 at Charleston Dirty Birds 4 | Final |
| May 7, 2025 | L | Lexington Legends 4 at Charleston Dirty Birds 3 | Final |
| May 8, 2025 | L | Lexington Legends 2 at Charleston Dirty Birds 1 | Final |
| May 9, 2025 | L | Charleston Dirty Birds 6 at Southern Maryland Blue Crabs 7 | Final |
| May 10, 2025 | W | Charleston Dirty Birds 7 at Southern Maryland Blue Crabs 2 | Final |
| May 11, 2025 | L | Charleston Dirty Birds 2 at Southern Maryland Blue Crabs 3 | Final |
| May 13, 2025 | W | Staten Island FerryHawks 3 at Charleston Dirty Birds 7 | Final |
| May 14, 2025 | W | Staten Island FerryHawks 5 at Charleston Dirty Birds 7 | Final |
| May 15, 2025 | L | Staten Island FerryHawks 9 at Charleston Dirty Birds 2 | Final |
| May 16, 2025 | W | Southern Maryland Blue Crabs 0 at Charleston Dirty Birds 3 | Final |
| May 17, 2025 | W | Southern Maryland Blue Crabs 3 at Charleston Dirty Birds 9 | Final |
| May 18, 2025 | W | Southern Maryland Blue Crabs 5 at Charleston Dirty Birds 8 | Final |
| May 20, 2025 | L | High Point Rockers 8 at Charleston Dirty Birds 2 | Final |
| May 21, 2025 | L | High Point Rockers 12 at Charleston Dirty Birds 4 | Final |
| May 22, 2025 | W | High Point Rockers 2 at Charleston Dirty Birds 7 | Final |
| May 23, 2025 | W | Charleston Dirty Birds 3 at Lexington Legends 1 | Final |
| May 24, 2025 | L | Charleston Dirty Birds 4 at Lexington Legends 5 | Final |
| May 25, 2025 | W | Charleston Dirty Birds 4 at Lexington Legends 2 | Final |
| May 27, 2025 | L | High Point Rockers 5 at Charleston Dirty Birds 0 | Final |
| May 28, 2025 | W | High Point Rockers 1 at Charleston Dirty Birds 7 | Final |
| May 29, 2025 | L | High Point Rockers 6 at Charleston Dirty Birds 2 | Final |
| May 30, 2025 | W | Lexington Legends 6 at Charleston Dirty Birds 7 | Final |
| May 31, 2025 | W | Lexington Legends 4 at Charleston Dirty Birds 11 | Final |
| June 1, 2025 | W | Lexington Legends 2 at Charleston Dirty Birds 3 | Final |
| June 3, 2025 | W | Charleston Dirty Birds 5 at High Point Rockers 4 | Final |
| June 4, 2025 | L | Charleston Dirty Birds 2 at High Point Rockers 3 | Final |
| June 5, 2025 | W | Charleston Dirty Birds 2 at High Point Rockers 1 | Final |
| June 6, 2025 | L | Charleston Dirty Birds 4 at Gastonia Ghost Peppers 15 | Final |
| June 7, 2025 | L | Charleston Dirty Birds 6 at Gastonia Ghost Peppers 7 | Final |
| June 8, 2025 | W | Charleston Dirty Birds 11 at Gastonia Ghost Peppers 8 | Final |
| June 10, 2025 | L | Long Island Ducks 8 at Charleston Dirty Birds 5 | Final |
| June 11, 2025 | W | Long Island Ducks 4 at Charleston Dirty Birds 5 | Final |
| June 12, 2025 | L | Long Island Ducks 4 at Charleston Dirty Birds 3 | Final |
| June 13, 2025 | L | Lancaster Stormers 15 at Charleston Dirty Birds 6 | Final |
| June 14, 2025 | W | Lancaster Stormers 1 at Charleston Dirty Birds 10 | Final |
| June 15, 2025 | W | Lancaster Stormers 3 at Charleston Dirty Birds 4 | Final |
| June 17, 2025 | | Charleston Dirty Birds at Southern Maryland Blue Crabs | 6:35 p.m. |
| June 18, 2025 | | Charleston Dirty Birds at Southern Maryland Blue Crabs | 6:35 p.m. |
| June 19, 2025 | | Charleston Dirty Birds at Southern Maryland Blue Crabs | 6:35 p.m. |
| June 20, 2025 | | Charleston Dirty Birds at Hagerstown Flying Boxcars | 6:30 p.m. |
| June 21, 2025 | | Charleston Dirty Birds at Hagerstown Flying Boxcars | 6:00 p.m. |
| June 22, 2025 | | Charleston Dirty Birds at Hagerstown Flying Boxcars | 2:00 p.m. |
| June 24, 2025 | | Charleston Dirty Birds at Lexington Legends | 6:45 p.m. |
| June 25, 2025 | | Charleston Dirty Birds at Lexington Legends | 11:00 a.m. |
| June 26, 2025 | | Charleston Dirty Birds at Lexington Legends | 6:45 p.m. |
| June 27, 2025 | | Gastonia Ghost Peppers at Charleston Dirty Birds | 6:35 p.m. |
| June 28, 2025 | | Gastonia Ghost Peppers at Charleston Dirty Birds | 6:35 p.m. |
| June 29, 2025 | | Gastonia Ghost Peppers at Charleston Dirty Birds | 3:04 p.m. |
| July 1, 2025 | | Lexington Legends at Charleston Dirty Birds | 6:35 p.m. |
| July 2, 2025 | | Lexington Legends at Charleston Dirty Birds | 6:35 p.m. |
| July 3, 2025 | | Lexington Legends at Charleston Dirty Birds | 6:35 p.m. |
| July 4, 2025 | | Charleston Dirty Birds at Lancaster Stormers | 6:45 p.m. |
| July 5, 2025 | | Charleston Dirty Birds at Lancaster Stormers | 6:45 p.m. |
| July 6, 2025 | | Charleston Dirty Birds at Lancaster Stormers | 2:00 p.m. |
| July 8, 2025 | | Charleston Dirty Birds at Gastonia Ghost Peppers | 6:30 p.m. |
| July 9, 2025 | | Charleston Dirty Birds at Gastonia Ghost Peppers | 12:30 p.m. |
| July 10, 2025 | | Charleston Dirty Birds at Gastonia Ghost Peppers | 6:30 p.m. |
| July 11, 2025 | | Hagerstown Flying Boxcars at Charleston Dirty Birds | 6:35 p.m. |
| July 12, 2025 | | Hagerstown Flying Boxcars at Charleston Dirty Birds | 6:35 p.m. |
| July 13, 2025 | | Hagerstown Flying Boxcars at Charleston Dirty Birds | 3:04 p.m. |
| July 15, 2025 | | Southern Maryland Blue Crabs at Charleston Dirty Birds | 6:35 p.m. |
| July 16, 2025 | | Southern Maryland Blue Crabs at Charleston Dirty Birds | 12:05 p.m. |
| July 17, 2025 | | Southern Maryland Blue Crabs at Charleston Dirty Birds | 6:35 p.m. |
| July 18, 2025 | | Charleston Dirty Birds at Long Island Ducks | 6:35 p.m. |
| July 19, 2025 | | Charleston Dirty Birds at Long Island Ducks | 6:35 p.m. |
| July 20, 2025 | | Charleston Dirty Birds at Long Island Ducks | 5:05 p.m. |
| July 22, 2025 | | Charleston Dirty Birds at High Point Rockers | 6:35 p.m. |
| July 23, 2025 | | Charleston Dirty Birds at High Point Rockers | 6:35 p.m. |
| July 24, 2025 | | Charleston Dirty Birds at High Point Rockers | 6:35 p.m. |
| July 25, 2025 | | Lexington Legends at Charleston Dirty Birds | 6:35 p.m. |
| July 26, 2025 | | Lexington Legends at Charleston Dirty Birds | 6:35 p.m. |
| July 27, 2025 | | Lexington Legends at Charleston Dirty Birds | 3:04 p.m. |
| July 29, 2025 | | Southern Maryland Blue Crabs at Charleston Dirty Birds | 6:35 p.m. |
| July 30, 2025 | | Southern Maryland Blue Crabs at Charleston Dirty Birds | 6:35 p.m. |
| July 31, 2025 | | Southern Maryland Blue Crabs at Charleston Dirty Birds | 6:35 p.m. |
| August 1, 2025 | | York Revolution at Charleston Dirty Birds | 6:35 p.m. |
| August 2, 2025 | | York Revolution at Charleston Dirty Birds | 6:35 p.m. |
| August 3, 2025 | | York Revolution at Charleston Dirty Birds | 3:04 p.m. |
| August 5, 2025 | | Charleston Dirty Birds at Gastonia Ghost Peppers | 6:30 p.m. |
| August 7, 2025 | | Charleston Dirty Birds at Gastonia Ghost Peppers | 12:30 p.m. |
| August 7, 2025 | | Charleston Dirty Birds at Gastonia Ghost Peppers | 6:30 p.m. |
| August 8, 2025 | | Charleston Dirty Birds at Gastonia Ghost Peppers | 7:00 p.m. |
| August 9, 2025 | | Charleston Dirty Birds at Gastonia Ghost Peppers | 7:00 p.m. |
| August 10, 2025 | | Charleston Dirty Birds at Gastonia Ghost Peppers | 4:00 p.m. |
| August 12, 2025 | | High Point Rockers at Charleston Dirty Birds | 6:35 p.m. |
| August 13, 2025 | | High Point Rockers at Charleston Dirty Birds | 12:05 p.m. |
| August 14, 2025 | | High Point Rockers at Charleston Dirty Birds | 6:35 p.m. |
| August 15, 2025 | | High Point Rockers at Charleston Dirty Birds | 6:35 p.m. |
| August 16, 2025 | | High Point Rockers at Charleston Dirty Birds | 6:35 p.m. |
| August 17, 2025 | | High Point Rockers at Charleston Dirty Birds | 3:04 p.m. |
| August 19, 2025 | | Charleston Dirty Birds at Staten Island FerryHawks | 6:30 p.m. |
| August 20, 2025 | | Charleston Dirty Birds at Staten Island FerryHawks | 6:30 p.m. |
| August 21, 2025 | | Charleston Dirty Birds at Staten Island FerryHawks | 6:30 p.m. |
| August 22, 2025 | | Charleston Dirty Birds at York Revolution | 6:30 p.m. |
| August 23, 2025 | | Charleston Dirty Birds at York Revolution | 6:30 p.m. |
| August 24, 2025 | | Charleston Dirty Birds at York Revolution | 1:00 p.m. |
| August 26, 2025 | | Charleston Dirty Birds at High Point Rockers | 6:35 p.m. |
| August 27, 2025 | | Charleston Dirty Birds at High Point Rockers | 6:35 p.m. |
| August 28, 2025 | | Charleston Dirty Birds at High Point Rockers | 6:35 p.m. |
| August 29, 2025 | | Gastonia Ghost Peppers at Charleston Dirty Birds | 6:35 p.m. |
| August 30, 2025 | | Gastonia Ghost Peppers at Charleston Dirty Birds | 6:35 p.m. |
| August 31, 2025 | | Gastonia Ghost Peppers at Charleston Dirty Birds | 3:04 p.m. |
| September 2, 2025 | | Charleston Dirty Birds at Lexington Legends | 6:45 p.m. |
| September 3, 2025 | | Charleston Dirty Birds at Lexington Legends | 6:45 p.m. |
| September 4, 2025 | | Charleston Dirty Birds at Lexington Legends | 6:45 p.m. |
| September 5, 2025 | | Charleston Dirty Birds at Lexington Legends | 7:00 p.m. |
| September 6, 2025 | | Charleston Dirty Birds at Lexington Legends | 7:00 p.m. |
| September 7, 2025 | | Charleston Dirty Birds at Lexington Legends | 2:00 p.m. |
| September 9, 2025 | | Gastonia Ghost Peppers at Charleston Dirty Birds | 6:35 p.m. |
| September 10, 2025 | | Gastonia Ghost Peppers at Charleston Dirty Birds | 6:35 p.m. |
| September 11, 2025 | | Gastonia Ghost Peppers at Charleston Dirty Birds | 6:35 p.m. |
| September 12, 2025 | | Gastonia Ghost Peppers at Charleston Dirty Birds | 6:35 p.m. |
| September 13, 2025 | | Gastonia Ghost Peppers at Charleston Dirty Birds | 6:35 p.m. |
| September 14, 2025 | | Gastonia Ghost Peppers at Charleston Dirty Birds | 3:04 p.m. |
| September 16, 2025 | | Charleston Dirty Birds at High Point Rockers | 6:35 p.m. |
| September 17, 2025 | | Charleston Dirty Birds at High Point Rockers | 6:35 p.m. |
| September 18, 2025 | | Charleston Dirty Birds at High Point Rockers | 6:35 p.m. |
Charleston Dirty Birds Schedule
