| | | |
| March 9, 2025 | T | Vancouver Whitecaps FC 2 3 at LAFC2 3 | Final (PK 4-2) |
| March 14, 2025 | L | Vancouver Whitecaps FC 2 2 at North Texas SC 3 | Final |
| March 29, 2025 | T | Portland Timbers 2 1 at Vancouver Whitecaps FC 2 1 | Final (PK 4-5) |
| April 6, 2025 | L | Vancouver Whitecaps FC 2 3 at Tacoma Defiance 5 | Final |
| April 19, 2025 | W | Austin FC II 0 at Vancouver Whitecaps FC 2 4 | Final |
| April 23, 2025 | L | Houston Dynamo 2 3 at Vancouver Whitecaps FC 2 1 | Final |
| April 27, 2025 | L | Ventura County FC 3 at Vancouver Whitecaps FC 2 2 | Final |
| May 3, 2025 | T | Real Monarchs 1 at Vancouver Whitecaps FC 2 1 | Final (PK 1-3) |
| May 9, 2025 | L | Vancouver Whitecaps FC 2 0 at Portland Timbers 2 1 | Final |
| May 14, 2025 | W | Tacoma Defiance 0 at Vancouver Whitecaps FC 2 5 | Final |
| May 18, 2025 | L | Ventura County FC 2 at Vancouver Whitecaps FC 2 0 | Final |
| May 28, 2025 | W | Vancouver Whitecaps FC 2 3 at Minnesota United FC 2 2 | Final |
| June 8, 2025 | | Vancouver Whitecaps FC 2 at The Town FC | Ppd. |
| June 12, 2025 | W | LAFC2 0 at Vancouver Whitecaps FC 2 2 | Final |
| June 21, 2025 | W | North Texas SC 3 at Vancouver Whitecaps FC 2 4 | Final |
| June 29, 2025 | L | Real Monarchs 3 at Vancouver Whitecaps FC 2 2 | Final |
| July 3, 2025 | W | Vancouver Whitecaps FC 2 2 at Ventura County FC 1 | Final |
| July 13, 2025 | T | Vancouver Whitecaps FC 2 0 at Colorado Rapids 2 0 | Final (PK 6-7) |
| July 17, 2025 | W | Vancouver Whitecaps FC 2 4 at Houston Dynamo 2 2 | Final |
| July 31, 2025 | L | Sporting Kansas City II 3 at Vancouver Whitecaps FC 2 2 | Final |
| August 6, 2025 | L | St. Louis City SC 2 4 at Vancouver Whitecaps FC 2 2 | Final |
| August 9, 2025 | L | Vancouver Whitecaps FC 2 1 at The Town FC 2 | Final |
| August 21, 2025 | W | Vancouver Whitecaps FC 2 3 at LAFC2 1 | Final |
| August 31, 2025 | W | Portland Timbers 2 1 at Vancouver Whitecaps FC 2 4 | Final |
| September 4, 2025 | W | Vancouver Whitecaps FC 2 3 at Tacoma Defiance 1 | Final |
| September 13, 2025 | W | The Town FC 1 at Vancouver Whitecaps FC 2 3 | Final |
| September 19, 2025 | T | Vancouver Whitecaps FC 2 2 at Sporting Kansas City II 2 | Final (PK 4-2) |
| October 5, 2025 | L | Vancouver Whitecaps FC 2 1 at Real Monarchs 4 | Final |
| October 19, 2025 | L | Vancouver Whitecaps FC 2 2 at Colorado Rapids 2 3 (Playoff) | Final |
Vancouver Whitecaps FC 2 Schedule
