DC Defenders Schedule
All times Eastern
Complete Schedule
| March 30, 2025 | W | Birmingham Stallions 11 at DC Defenders 18 | Final |
| April 5, 2025 | W | Memphis Showboats 12 at DC Defenders 17 | Final |
| April 13, 2025 | W | DC Defenders 27 at St. Louis Battlehawks 15 | Final |
| April 20, 2025 | L | San Antonio Brahmas 24 at DC Defenders 18 | Final |
| April 27, 2025 | W | DC Defenders 37 at Arlington Renegades 33 | Final |
| May 4, 2025 | L | DC Defenders 14 at Michigan Panthers 38 | Final |
| May 9, 2025 | W | DC Defenders 32 at San Antonio Brahmas 24 | Final |
| May 18, 2025 | W | Arlington Renegades 30 at DC Defenders 33 | Final |
| May 25, 2025 | L | DC Defenders 21 at Houston Roughnecks 24 | Final |
| May 30, 2025 | L | St. Louis Battlehawks 13 at DC Defenders 8 | Final |
| June 8, 2025 | W | DC Defenders 36 at St. Louis Battlehawks 18 (Playoff) | Final |
| June 14, 2025 | W | DC Defenders 58 at Michigan Panthers 34 (Championship; St. Louis) | Final |
