| | | |
| March 28, 2025 | L | Indianapolis Indians 0 at St. Paul Saints 11 | Final |
| March 29, 2025 | | Indianapolis Indians at St. Paul Saints | Ppd. |
| March 30, 2025 | | Indianapolis Indians at St. Paul Saints | Ppd. |
| April 1, 2025 | L | Iowa Cubs 2 at Indianapolis Indians 1 | Final |
| April 2, 2025 | | Iowa Cubs at Indianapolis Indians | Ppd. |
| April 3, 2025 | W | Iowa Cubs 6 at Indianapolis Indians 7 | Final (8) |
| April 3, 2025 | L | Iowa Cubs 6 at Indianapolis Indians 1 | Final (7) |
| April 4, 2025 | | Iowa Cubs at Indianapolis Indians | Susp. |
| April 5, 2025 | | Iowa Cubs at Indianapolis Indians (Game 2) | Cancelled |
| April 5, 2025 | | Iowa Cubs at Indianapolis Indians (Game 1) | Susp. |
| April 6, 2025 | W | Iowa Cubs 4 at Indianapolis Indians 5 (Game 1) | Final (10) |
| April 6, 2025 | L | Iowa Cubs 4 at Indianapolis Indians 1 (Game 2) | Final |
| April 8, 2025 | L | Indianapolis Indians 2 at Louisville Bats 4 | Final |
| April 9, 2025 | W | Indianapolis Indians 7 at Louisville Bats 3 | Final |
| April 10, 2025 | | Indianapolis Indians at Louisville Bats | Ppd. |
| April 11, 2025 | W | Indianapolis Indians 6 at Louisville Bats 3 | Final |
| April 12, 2025 | L | Indianapolis Indians 1 at Louisville Bats 5 (Game 1) | Final (7) |
| April 12, 2025 | L | Indianapolis Indians 2 at Louisville Bats 7 (Game 2) | Final (7) |
| April 13, 2025 | W | Indianapolis Indians 6 at Louisville Bats 5 | Final (10) |
| April 15, 2025 | L | Toledo Mud Hens 11 at Indianapolis Indians 6 | Final |
| April 16, 2025 | W | Toledo Mud Hens 4 at Indianapolis Indians 5 | Final (12) |
| April 17, 2025 | W | Toledo Mud Hens 6 at Indianapolis Indians 7 | Final |
| April 18, 2025 | W | Toledo Mud Hens 4 at Indianapolis Indians 5 | Final (11) |
| April 19, 2025 | W | Toledo Mud Hens 2 at Indianapolis Indians 6 | Final |
| April 20, 2025 | W | Toledo Mud Hens 6 at Indianapolis Indians 10 | Final |
| April 22, 2025 | L | Indianapolis Indians 4 at St. Paul Saints 16 | Final |
| April 23, 2025 | L | Indianapolis Indians 1 at St. Paul Saints 5 (Game 1) | Final (7) |
| April 23, 2025 | W | Indianapolis Indians 4 at St. Paul Saints 2 (Game 2) | Final (7) |
| April 24, 2025 | | Indianapolis Indians at St. Paul Saints | Ppd. |
| April 25, 2025 | W | Indianapolis Indians 10 at St. Paul Saints 0 (Game 1) | Final (7) |
| April 25, 2025 | L | Indianapolis Indians 0 at St. Paul Saints 3 (Game 2) | Final (7) |
| April 26, 2025 | W | Indianapolis Indians 6 at St. Paul Saints 5 | Final |
| April 27, 2025 | L | Indianapolis Indians 3 at St. Paul Saints 5 | Final |
| April 29, 2025 | W | Indianapolis Indians 9 at Omaha Storm Chasers 7 | Final |
| April 30, 2025 | L | Indianapolis Indians 6 at Omaha Storm Chasers 9 | Final |
| May 1, 2025 | W | Indianapolis Indians 7 at Omaha Storm Chasers 2 | Final |
| May 2, 2025 | W | Indianapolis Indians 6 at Omaha Storm Chasers 0 | Final |
| May 3, 2025 | L | Indianapolis Indians 1 at Omaha Storm Chasers 5 | Final |
| May 4, 2025 | L | Indianapolis Indians 1 at Omaha Storm Chasers 8 | Final |
| May 6, 2025 | W | Columbus Clippers 1 at Indianapolis Indians 4 | Final |
| May 7, 2025 | L | Columbus Clippers 4 at Indianapolis Indians 3 | Final |
| May 8, 2025 | W | Columbus Clippers 3 at Indianapolis Indians 4 | Final |
| May 9, 2025 | W | Columbus Clippers 2 at Indianapolis Indians 3 | Final |
| May 10, 2025 | L | Columbus Clippers 1 at Indianapolis Indians 0 | Final |
| May 11, 2025 | W | Columbus Clippers 0 at Indianapolis Indians 2 | Final |
| May 13, 2025 | W | Louisville Bats 1 at Indianapolis Indians 3 | Final |
| May 14, 2025 | W | Louisville Bats 8 at Indianapolis Indians 9 | Final |
| May 15, 2025 | W | Louisville Bats 4 at Indianapolis Indians 7 | Final |
| May 16, 2025 | | Louisville Bats at Indianapolis Indians | Ppd. |
| May 17, 2025 | W | Louisville Bats 4 at Indianapolis Indians 6 (Game 1) | Final (7) |
| May 17, 2025 | W | Louisville Bats 2 at Indianapolis Indians 8 (Game 2) | Final (7) |
| May 18, 2025 | W | Louisville Bats 3 at Indianapolis Indians 4 | Final |
| May 20, 2025 | | Indianapolis Indians at Toledo Mud Hens | Ppd. |
| May 21, 2025 | L | Indianapolis Indians 0 at Toledo Mud Hens 3 | Final (7) |
| May 22, 2025 | L | Indianapolis Indians 1 at Toledo Mud Hens 2 (Game 1) | Final (7) |
| May 22, 2025 | L | Indianapolis Indians 0 at Toledo Mud Hens 5 (Game 2) | Final (7) |
| May 23, 2025 | W | Indianapolis Indians 4 at Toledo Mud Hens 0 | Final |
| May 24, 2025 | L | Indianapolis Indians 4 at Toledo Mud Hens 5 | Final |
| May 25, 2025 | L | Indianapolis Indians 0 at Toledo Mud Hens 8 | Final |
| May 26, 2025 | W | Nashville Sounds 1 at Indianapolis Indians 2 | Final |
| May 28, 2025 | L | Nashville Sounds 9 at Indianapolis Indians 6 | Final |
| May 29, 2025 | W | Nashville Sounds 1 at Indianapolis Indians 7 | Final |
| May 30, 2025 | W | Nashville Sounds 4 at Indianapolis Indians 5 | Final |
| May 31, 2025 | W | Nashville Sounds 4 at Indianapolis Indians 8 | Final |
| June 1, 2025 | L | Nashville Sounds 11 at Indianapolis Indians 1 | Final |
| June 3, 2025 | L | Indianapolis Indians 2 at Memphis Redbirds 4 | Final |
| June 4, 2025 | W | Indianapolis Indians 10 at Memphis Redbirds 3 | Final |
| June 5, 2025 | W | Indianapolis Indians 10 at Memphis Redbirds 9 | Final |
| June 6, 2025 | L | Indianapolis Indians 1 at Memphis Redbirds 4 | Final |
| June 7, 2025 | L | Indianapolis Indians 2 at Memphis Redbirds 10 | Final |
| June 8, 2025 | W | Indianapolis Indians 6 at Memphis Redbirds 2 | Final |
| June 10, 2025 | W | St. Paul Saints 2 at Indianapolis Indians 3 | Final (10) |
| June 11, 2025 | L | St. Paul Saints 5 at Indianapolis Indians 4 | Final |
| June 12, 2025 | W | St. Paul Saints 2 at Indianapolis Indians 6 (Game 1) | Final (7) |
| June 12, 2025 | W | Indianapolis Indians 5 at St. Paul Saints 0 (Game 2) | Final (7) |
| June 13, 2025 | W | St. Paul Saints 6 at Indianapolis Indians 7 | Final (11) |
| June 14, 2025 | W | St. Paul Saints 2 at Indianapolis Indians 4 | Final |
| June 15, 2025 | W | St. Paul Saints 3 at Indianapolis Indians 7 | Final |
| June 17, 2025 | W | Indianapolis Indians 7 at Columbus Clippers 2 | Final |
| June 18, 2025 | | Indianapolis Indians at Columbus Clippers | Susp. |
| June 19, 2025 | L | Indianapolis Indians 7 at Columbus Clippers 8 (Game 1) | Final |
| June 19, 2025 | W | Indianapolis Indians 8 at Columbus Clippers 6 (Game 2) | Final (7) |
| June 20, 2025 | L | Indianapolis Indians 2 at Columbus Clippers 4 | Final |
| June 21, 2025 | L | Indianapolis Indians 1 at Columbus Clippers 4 | Final |
| June 22, 2025 | L | Indianapolis Indians 6 at Columbus Clippers 8 | Final |
| June 24, 2025 | W | Omaha Storm Chasers 1 at Indianapolis Indians 9 | Final |
| June 25, 2025 | L | Omaha Storm Chasers 7 at Indianapolis Indians 5 | Final (10) |
| June 26, 2025 | L | Omaha Storm Chasers 17 at Indianapolis Indians 2 | Final |
| June 27, 2025 | W | Omaha Storm Chasers 0 at Indianapolis Indians 2 | Final |
| June 28, 2025 | W | Omaha Storm Chasers 1 at Indianapolis Indians 12 | Final |
| June 29, 2025 | W | Omaha Storm Chasers 2 at Indianapolis Indians 3 | Final |
| July 1, 2025 | L | Indianapolis Indians 5 at Louisville Bats 12 | Final |
| July 2, 2025 | W | Indianapolis Indians 3 at Louisville Bats 2 | Final |
| July 3, 2025 | W | Indianapolis Indians 11 at Louisville Bats 3 | Final |
| July 4, 2025 | W | Louisville Bats 1 at Indianapolis Indians 8 | Final |
| July 5, 2025 | L | Louisville Bats 3 at Indianapolis Indians 1 | Final |
| July 6, 2025 | W | Louisville Bats 11 at Indianapolis Indians 13 | Final |
| July 8, 2025 | W | Gwinnett Stripers 1 at Indianapolis Indians 8 | Final |
| July 9, 2025 | W | Gwinnett Stripers 2 at Indianapolis Indians 3 | Final |
| July 10, 2025 | W | Gwinnett Stripers 0 at Indianapolis Indians 3 | Final |
| July 11, 2025 | L | Gwinnett Stripers 8 at Indianapolis Indians 4 | Final (10) |
| July 12, 2025 | W | Gwinnett Stripers 1 at Indianapolis Indians 6 | Final |
| July 13, 2025 | W | Gwinnett Stripers 5 at Indianapolis Indians 6 | Final |
| July 18, 2025 | L | Indianapolis Indians 1 at Nashville Sounds 6 | Final (6) |
| July 19, 2025 | L | Indianapolis Indians 4 at Nashville Sounds 7 | Final |
| July 20, 2025 | W | Indianapolis Indians 7 at Nashville Sounds 3 | Final |
| July 22, 2025 | W | Toledo Mud Hens 1 at Indianapolis Indians 7 | Final |
| July 23, 2025 | W | Toledo Mud Hens 6 at Indianapolis Indians 9 | Final |
| July 24, 2025 | W | Toledo Mud Hens 2 at Indianapolis Indians 3 | Final |
| July 25, 2025 | L | Toledo Mud Hens 4 at Indianapolis Indians 3 | Final |
| July 26, 2025 | W | Toledo Mud Hens 4 at Indianapolis Indians 5 | Final |
| July 27, 2025 | W | Toledo Mud Hens 5 at Indianapolis Indians 6 | Final |
| July 29, 2025 | W | Indianapolis Indians 5 at Iowa Cubs 3 | Final |
| July 30, 2025 | L | Indianapolis Indians 2 at Iowa Cubs 5 | Final |
| July 31, 2025 | L | Indianapolis Indians 2 at Iowa Cubs 6 | Final |
| August 1, 2025 | W | Indianapolis Indians 8 at Iowa Cubs 5 | Final (10) |
| August 2, 2025 | W | Indianapolis Indians 5 at Iowa Cubs 2 | Final |
| August 3, 2025 | W | Indianapolis Indians 12 at Iowa Cubs 4 | Final |
| August 5, 2025 | L | Omaha Storm Chasers 7 at Indianapolis Indians 6 | Final (10) |
| August 6, 2025 | L | Omaha Storm Chasers 5 at Indianapolis Indians 4 | Final |
| August 7, 2025 | W | Omaha Storm Chasers 2 at Indianapolis Indians 4 | Final |
| August 8, 2025 | L | Omaha Storm Chasers 2 at Indianapolis Indians 1 | Final |
| August 9, 2025 | L | Omaha Storm Chasers 10 at Indianapolis Indians 4 | Final |
| August 10, 2025 | L | Omaha Storm Chasers 6 at Indianapolis Indians 1 | Final |
| August 12, 2025 | W | Indianapolis Indians 6 at Scranton/Wilkes-Barre RailRiders 5 | Final |
| August 13, 2025 | L | Indianapolis Indians 5 at Scranton/Wilkes-Barre RailRiders 6 | Final |
| August 14, 2025 | W | Indianapolis Indians 9 at Scranton/Wilkes-Barre RailRiders 6 | Final |
| August 15, 2025 | W | Indianapolis Indians 6 at Scranton/Wilkes-Barre RailRiders 5 | Final (10) |
| August 16, 2025 | L | Indianapolis Indians 5 at Scranton/Wilkes-Barre RailRiders 11 | Final |
| August 17, 2025 | L | Indianapolis Indians 5 at Scranton/Wilkes-Barre RailRiders 7 | Final |
| August 19, 2025 | W | Indianapolis Indians 6 at Syracuse Mets 5 | Final |
| August 20, 2025 | W | Indianapolis Indians 6 at Syracuse Mets 0 | Final |
| August 21, 2025 | W | Indianapolis Indians 16 at Syracuse Mets 1 | Final |
| August 22, 2025 | L | Indianapolis Indians 0 at Syracuse Mets 5 | Final |
| August 23, 2025 | L | Indianapolis Indians 0 at Syracuse Mets 4 | Final |
| August 24, 2025 | W | Indianapolis Indians 12 at Syracuse Mets 9 | Final |
| August 26, 2025 | L | Buffalo Bisons 5 at Indianapolis Indians 4 | Final |
| August 27, 2025 | L | Buffalo Bisons 6 at Indianapolis Indians 3 | Final |
| August 28, 2025 | L | Buffalo Bisons 5 at Indianapolis Indians 3 | Final |
| August 29, 2025 | W | Buffalo Bisons 3 at Indianapolis Indians 5 | Final |
| August 30, 2025 | W | Buffalo Bisons 1 at Indianapolis Indians 2 | Final |
| August 31, 2025 | L | Buffalo Bisons 6 at Indianapolis Indians 2 | Final |
| September 2, 2025 | W | Indianapolis Indians 5 at Columbus Clippers 3 | Final |
| September 3, 2025 | L | Indianapolis Indians 2 at Columbus Clippers 9 | Final |
| September 4, 2025 | L | Indianapolis Indians 3 at Columbus Clippers 5 | Final |
| September 5, 2025 | W | Indianapolis Indians 6 at Columbus Clippers 5 | Final |
| September 6, 2025 | L | Indianapolis Indians 0 at Columbus Clippers 12 | Final |
| September 7, 2025 | W | Indianapolis Indians 10 at Columbus Clippers 9 | Final |
| September 9, 2025 | L | Iowa Cubs 7 at Indianapolis Indians 0 | Final (11) |
| September 10, 2025 | W | Iowa Cubs 3 at Indianapolis Indians 8 | Final |
| September 11, 2025 | L | Iowa Cubs 6 at Indianapolis Indians 2 | Final |
| September 12, 2025 | W | Iowa Cubs 0 at Indianapolis Indians 4 | Final |
| September 13, 2025 | W | Iowa Cubs 2 at Indianapolis Indians 5 | Final |
| September 14, 2025 | W | Iowa Cubs 0 at Indianapolis Indians 4 | Final |
| September 16, 2025 | W | Indianapolis Indians 8 at Gwinnett Stripers 1 | Final |
| September 17, 2025 | L | Indianapolis Indians 0 at Gwinnett Stripers 5 | Final |
| September 18, 2025 | W | Indianapolis Indians 6 at Gwinnett Stripers 3 | Final |
| September 19, 2025 | W | Indianapolis Indians 12 at Gwinnett Stripers 6 | Final |
| September 20, 2025 | W | Indianapolis Indians 5 at Gwinnett Stripers 3 | Final |
| September 21, 2025 | W | Indianapolis Indians 6 at Gwinnett Stripers 4 | Final |
Indianapolis Indians Schedule
