| | | |
| April 4, 2025 | W | Harrisburg Senators 1 at Erie SeaWolves 5 | Final |
| April 5, 2025 | W | Harrisburg Senators 1 at Erie SeaWolves 10 | Final |
| April 6, 2025 | W | Harrisburg Senators 2 at Erie SeaWolves 5 | Final |
| April 8, 2025 | L | Erie SeaWolves 4 at Chesapeake Baysox 5 | Final |
| April 9, 2025 | W | Erie SeaWolves 7 at Chesapeake Baysox 4 | Final |
| April 10, 2025 | L | Erie SeaWolves 2 at Chesapeake Baysox 3 | Final |
| April 11, 2025 | | Erie SeaWolves at Chesapeake Baysox | Ppd. |
| April 12, 2025 | W | Erie SeaWolves 18 at Chesapeake Baysox 2 (Game 1) | Final (7) |
| April 12, 2025 | L | Erie SeaWolves 3 at Chesapeake Baysox 4 (Game 2) | Final (7) |
| April 13, 2025 | W | Erie SeaWolves 1 at Chesapeake Baysox 0 | Final |
| April 15, 2025 | W | Akron RubberDucks 7 at Erie SeaWolves 8 | Final |
| April 16, 2025 | W | Akron RubberDucks 0 at Erie SeaWolves 4 | Final |
| April 17, 2025 | L | Akron RubberDucks 6 at Erie SeaWolves 3 | Final |
| April 18, 2025 | L | Akron RubberDucks 9 at Erie SeaWolves 6 | Final |
| April 19, 2025 | W | Akron RubberDucks 2 at Erie SeaWolves 6 | Final |
| April 20, 2025 | W | Akron RubberDucks 1 at Erie SeaWolves 5 | Final |
| April 22, 2025 | W | Erie SeaWolves 6 at Harrisburg Senators 2 | Final |
| April 23, 2025 | W | Erie SeaWolves 10 at Harrisburg Senators 3 | Final |
| April 24, 2025 | L | Erie SeaWolves 2 at Harrisburg Senators 4 | Final |
| April 25, 2025 | W | Erie SeaWolves 8 at Harrisburg Senators 5 | Final |
| April 26, 2025 | W | Erie SeaWolves 8 at Harrisburg Senators 3 | Final |
| April 27, 2025 | L | Erie SeaWolves 4 at Harrisburg Senators 5 | Final (10) |
| April 29, 2025 | W | Binghamton Rumble Ponies 3 at Erie SeaWolves 13 | Final (8) |
| April 30, 2025 | L | Binghamton Rumble Ponies 3 at Erie SeaWolves 2 | Final |
| May 1, 2025 | | Binghamton Rumble Ponies at Erie SeaWolves | Ppd. |
| May 2, 2025 | L | Binghamton Rumble Ponies 4 at Erie SeaWolves 1 (Game 1) | Final (7) |
| May 2, 2025 | W | Binghamton Rumble Ponies 0 at Erie SeaWolves 3 (Game 2) | Final (7) |
| May 3, 2025 | | Binghamton Rumble Ponies at Erie SeaWolves | Ppd. |
| May 4, 2025 | W | Binghamton Rumble Ponies 0 at Erie SeaWolves 1 (Game 1) | Final (7) |
| May 4, 2025 | L | Binghamton Rumble Ponies 6 at Erie SeaWolves 4 (Game 2) | Final (7) |
| May 6, 2025 | W | Altoona Curve 0 at Erie SeaWolves 3 | Final |
| May 7, 2025 | W | Altoona Curve 4 at Erie SeaWolves 6 | Final (12) |
| May 8, 2025 | W | Altoona Curve 3 at Erie SeaWolves 4 | Final |
| May 9, 2025 | W | Altoona Curve 0 at Erie SeaWolves 7 | Final |
| May 10, 2025 | L | Altoona Curve 6 at Erie SeaWolves 4 | Final |
| May 11, 2025 | L | Altoona Curve 3 at Erie SeaWolves 2 | Final |
| May 13, 2025 | W | Erie SeaWolves 3 at Richmond Flying Squirrels 1 | Final |
| May 14, 2025 | | Erie SeaWolves at Richmond Flying Squirrels | Ppd. |
| May 15, 2025 | L | Erie SeaWolves 1 at Richmond Flying Squirrels 3 (Game 1) | Final (7) |
| May 15, 2025 | W | Erie SeaWolves 3 at Richmond Flying Squirrels 2 (Game 2) | Final (7) |
| May 16, 2025 | L | Erie SeaWolves 1 at Richmond Flying Squirrels 5 | Final |
| May 17, 2025 | W | Erie SeaWolves 8 at Richmond Flying Squirrels 0 | Final |
| May 18, 2025 | W | Erie SeaWolves 7 at Richmond Flying Squirrels 4 | Final |
| May 20, 2025 | W | Hartford Yard Goats 0 at Erie SeaWolves 5 | Final |
| May 21, 2025 | W | Hartford Yard Goats 3 at Erie SeaWolves 18 | Final |
| May 22, 2025 | W | Hartford Yard Goats 2 at Erie SeaWolves 11 | Final |
| May 23, 2025 | W | Hartford Yard Goats 4 at Erie SeaWolves 5 | Final |
| May 24, 2025 | W | Hartford Yard Goats 3 at Erie SeaWolves 5 | Final |
| May 25, 2025 | L | Hartford Yard Goats 3 at Erie SeaWolves 0 | Final |
| May 27, 2025 | L | Erie SeaWolves 0 at Reading Fightin Phils 1 | Final |
| May 28, 2025 | | Erie SeaWolves at Reading Fightin Phils | Ppd. |
| May 29, 2025 | W | Erie SeaWolves 7 at Reading Fightin Phils 2 (Game 1) | Final (7) |
| May 29, 2025 | W | Erie SeaWolves 5 at Reading Fightin Phils 4 (Game 2) | Final (7) |
| May 30, 2025 | L | Erie SeaWolves 4 at Reading Fightin Phils 5 | Final |
| May 31, 2025 | W | Erie SeaWolves 11 at Reading Fightin Phils 1 | Final |
| June 1, 2025 | W | Erie SeaWolves 5 at Reading Fightin Phils 0 | Final |
| June 3, 2025 | W | Richmond Flying Squirrels 3 at Erie SeaWolves 8 | Final |
| June 4, 2025 | W | Richmond Flying Squirrels 6 at Erie SeaWolves 7 | Final |
| June 5, 2025 | W | Richmond Flying Squirrels 4 at Erie SeaWolves 12 | Final |
| June 6, 2025 | L | Richmond Flying Squirrels 4 at Erie SeaWolves 3 | Final (12) |
| June 7, 2025 | W | Richmond Flying Squirrels 2 at Erie SeaWolves 4 | Final |
| June 8, 2025 | L | Richmond Flying Squirrels 11 at Erie SeaWolves 9 | Final |
| June 10, 2025 | W | Erie SeaWolves 3 at Altoona Curve 0 | Final |
| June 11, 2025 | W | Erie SeaWolves 5 at Altoona Curve 2 | Final |
| June 12, 2025 | L | Erie SeaWolves 6 at Altoona Curve 10 | Final |
| June 13, 2025 | L | Erie SeaWolves 1 at Altoona Curve 4 | Final |
| June 14, 2025 | W | Erie SeaWolves 7 at Altoona Curve 2 | Final |
| June 15, 2025 | | Erie SeaWolves at Altoona Curve | 6:00 p.m. |
| June 17, 2025 | | Chesapeake Baysox at Erie SeaWolves | 6:05 p.m. |
| June 18, 2025 | | Chesapeake Baysox at Erie SeaWolves | 1:05 p.m. |
| June 19, 2025 | | Chesapeake Baysox at Erie SeaWolves | 6:05 p.m. |
| June 20, 2025 | | Chesapeake Baysox at Erie SeaWolves | 6:35 p.m. |
| June 21, 2025 | | Chesapeake Baysox at Erie SeaWolves | 6:05 p.m. |
| June 22, 2025 | | Chesapeake Baysox at Erie SeaWolves | 1:35 p.m. |
| June 24, 2025 | | Erie SeaWolves at Somerset Patriots | 6:35 p.m. |
| June 25, 2025 | | Erie SeaWolves at Somerset Patriots | 6:35 p.m. |
| June 26, 2025 | | Erie SeaWolves at Somerset Patriots | 6:35 p.m. |
| June 27, 2025 | | Erie SeaWolves at Somerset Patriots | 7:05 p.m. |
| June 28, 2025 | | Erie SeaWolves at Somerset Patriots | 7:05 p.m. |
| June 29, 2025 | | Erie SeaWolves at Somerset Patriots | 1:05 p.m. |
| July 1, 2025 | | Akron RubberDucks at Erie SeaWolves | 6:05 p.m. |
| July 2, 2025 | | Akron RubberDucks at Erie SeaWolves | 6:35 p.m. |
| July 3, 2025 | | Akron RubberDucks at Erie SeaWolves | 6:35 p.m. |
| July 4, 2025 | | Erie SeaWolves at Akron RubberDucks | 7:05 p.m. |
| July 5, 2025 | | Erie SeaWolves at Akron RubberDucks | 7:05 p.m. |
| July 6, 2025 | | Erie SeaWolves at Akron RubberDucks | 1:05 p.m. |
| July 8, 2025 | | Erie SeaWolves at Harrisburg Senators | 6:30 p.m. |
| July 9, 2025 | | Erie SeaWolves at Harrisburg Senators | 6:30 p.m. |
| July 10, 2025 | | Erie SeaWolves at Harrisburg Senators | 12:00 p.m. |
| July 11, 2025 | | Erie SeaWolves at Harrisburg Senators | 7:00 p.m. |
| July 12, 2025 | | Erie SeaWolves at Harrisburg Senators | 6:00 p.m. |
| July 13, 2025 | | Erie SeaWolves at Harrisburg Senators | 1:00 p.m. |
| July 18, 2025 | | Chesapeake Baysox at Erie SeaWolves | 6:35 p.m. |
| July 19, 2025 | | Chesapeake Baysox at Erie SeaWolves | 6:05 p.m. |
| July 20, 2025 | | Chesapeake Baysox at Erie SeaWolves | 1:35 p.m. |
| July 22, 2025 | | Somerset Patriots at Erie SeaWolves | 6:05 p.m. |
| July 23, 2025 | | Somerset Patriots at Erie SeaWolves | 1:05 p.m. |
| July 24, 2025 | | Somerset Patriots at Erie SeaWolves | 6:05 p.m. |
| July 25, 2025 | | Somerset Patriots at Erie SeaWolves | 6:35 p.m. |
| July 26, 2025 | | Somerset Patriots at Erie SeaWolves | 6:05 p.m. |
| July 27, 2025 | | Somerset Patriots at Erie SeaWolves | 1:35 p.m. |
| July 29, 2025 | | Erie SeaWolves at Akron RubberDucks | 12:05 p.m. |
| July 30, 2025 | | Erie SeaWolves at Akron RubberDucks | 6:35 p.m. |
| July 31, 2025 | | Erie SeaWolves at Akron RubberDucks | 6:35 p.m. |
| August 1, 2025 | | Erie SeaWolves at Akron RubberDucks | 7:05 p.m. |
| August 2, 2025 | | Erie SeaWolves at Akron RubberDucks | 7:05 p.m. |
| August 3, 2025 | | Erie SeaWolves at Akron RubberDucks | 1:05 p.m. |
| August 5, 2025 | | Richmond Flying Squirrels at Erie SeaWolves | 6:05 p.m. |
| August 6, 2025 | | Richmond Flying Squirrels at Erie SeaWolves | 1:05 p.m. |
| August 7, 2025 | | Richmond Flying Squirrels at Erie SeaWolves | 6:05 p.m. |
| August 8, 2025 | | Richmond Flying Squirrels at Erie SeaWolves | 6:05 p.m. |
| August 9, 2025 | | Richmond Flying Squirrels at Erie SeaWolves | 6:05 p.m. |
| August 10, 2025 | | Richmond Flying Squirrels at Erie SeaWolves | 1:35 p.m. |
| August 12, 2025 | | Erie SeaWolves at Chesapeake Baysox | 6:35 p.m. |
| August 13, 2025 | | Erie SeaWolves at Chesapeake Baysox | 6:35 p.m. |
| August 14, 2025 | | Erie SeaWolves at Chesapeake Baysox | 6:35 p.m. |
| August 15, 2025 | | Erie SeaWolves at Chesapeake Baysox | 7:05 p.m. |
| August 16, 2025 | | Erie SeaWolves at Chesapeake Baysox | 6:35 p.m. |
| August 17, 2025 | | Erie SeaWolves at Chesapeake Baysox | 1:05 p.m. |
| August 19, 2025 | | Harrisburg Senators at Erie SeaWolves | 6:05 p.m. |
| August 20, 2025 | | Harrisburg Senators at Erie SeaWolves | 6:05 p.m. |
| August 21, 2025 | | Harrisburg Senators at Erie SeaWolves | 6:05 p.m. |
| August 22, 2025 | | Harrisburg Senators at Erie SeaWolves | 6:05 p.m. |
| August 23, 2025 | | Harrisburg Senators at Erie SeaWolves | 6:05 p.m. |
| August 24, 2025 | | Harrisburg Senators at Erie SeaWolves | 1:35 p.m. |
| August 26, 2025 | | Erie SeaWolves at New Hampshire Fisher Cats | 6:35 p.m. |
| August 27, 2025 | | Erie SeaWolves at New Hampshire Fisher Cats | 6:35 p.m. |
| August 28, 2025 | | Erie SeaWolves at New Hampshire Fisher Cats | 6:35 p.m. |
| August 29, 2025 | | Erie SeaWolves at New Hampshire Fisher Cats | 6:35 p.m. |
| August 30, 2025 | | Erie SeaWolves at New Hampshire Fisher Cats | 6:35 p.m. |
| August 31, 2025 | | Erie SeaWolves at New Hampshire Fisher Cats | 1:35 p.m. |
| September 2, 2025 | | Erie SeaWolves at Portland Sea Dogs | 6:00 p.m. |
| September 3, 2025 | | Erie SeaWolves at Portland Sea Dogs | 6:00 p.m. |
| September 4, 2025 | | Erie SeaWolves at Portland Sea Dogs | 6:00 p.m. |
| September 5, 2025 | | Erie SeaWolves at Portland Sea Dogs | 6:00 p.m. |
| September 6, 2025 | | Erie SeaWolves at Portland Sea Dogs | 6:00 p.m. |
| September 7, 2025 | | Erie SeaWolves at Portland Sea Dogs | 1:00 p.m. |
| September 9, 2025 | | Altoona Curve at Erie SeaWolves | 6:05 p.m. |
| September 10, 2025 | | Altoona Curve at Erie SeaWolves | 6:05 p.m. |
| September 11, 2025 | | Altoona Curve at Erie SeaWolves | 6:05 p.m. |
| September 12, 2025 | | Altoona Curve at Erie SeaWolves | 6:05 p.m. |
| September 13, 2025 | | Altoona Curve at Erie SeaWolves | 6:05 p.m. |
| September 14, 2025 | | Altoona Curve at Erie SeaWolves | 1:35 p.m. |
Erie SeaWolves Schedule
