| | | |
| March 28, 2025 | L | Scranton/Wilkes-Barre RailRiders 4 at Lehigh Valley IronPigs 5 | Final |
| March 29, 2025 | L | Scranton/Wilkes-Barre RailRiders 4 at Lehigh Valley IronPigs 5 | Final |
| March 30, 2025 | W | Scranton/Wilkes-Barre RailRiders 14 at Lehigh Valley IronPigs 3 | Final |
| April 1, 2025 | W | Scranton/Wilkes-Barre RailRiders 6 at Syracuse Mets 2 | Final |
| April 2, 2025 | L | Scranton/Wilkes-Barre RailRiders 1 at Syracuse Mets 5 | Final |
| April 3, 2025 | W | Scranton/Wilkes-Barre RailRiders 5 at Syracuse Mets 1 | Final |
| April 4, 2025 | W | Scranton/Wilkes-Barre RailRiders 12 at Syracuse Mets 4 | Final |
| April 5, 2025 | L | Scranton/Wilkes-Barre RailRiders 4 at Syracuse Mets 7 | Final |
| April 6, 2025 | W | Scranton/Wilkes-Barre RailRiders 8 at Syracuse Mets 4 | Final |
| April 8, 2025 | | Rochester Red Wings at Scranton/Wilkes-Barre RailRiders | Ppd. |
| April 9, 2025 | L | Rochester Red Wings 7 at Scranton/Wilkes-Barre RailRiders 4 (Game 1) | Final (7) |
| April 9, 2025 | W | Rochester Red Wings 3 at Scranton/Wilkes-Barre RailRiders 4 (Game 2) | Final (7) |
| April 10, 2025 | | Rochester Red Wings at Scranton/Wilkes-Barre RailRiders | Ppd. |
| April 11, 2025 | W | Rochester Red Wings 7 at Scranton/Wilkes-Barre RailRiders 8 | Final (11) |
| April 12, 2025 | | Rochester Red Wings at Scranton/Wilkes-Barre RailRiders | Ppd. |
| April 13, 2025 | W | Rochester Red Wings 2 at Scranton/Wilkes-Barre RailRiders 3 (Game 1) | Final (7) |
| April 13, 2025 | W | Rochester Red Wings 0 at Scranton/Wilkes-Barre RailRiders 8 (Game 2) | Final (7) |
| April 15, 2025 | W | Scranton/Wilkes-Barre RailRiders 9 at Durham Bulls 1 | Final |
| April 16, 2025 | L | Scranton/Wilkes-Barre RailRiders 3 at Durham Bulls 4 | Final |
| April 17, 2025 | L | Scranton/Wilkes-Barre RailRiders 1 at Durham Bulls 7 | Final |
| April 18, 2025 | W | Scranton/Wilkes-Barre RailRiders 5 at Durham Bulls 0 | Final |
| April 19, 2025 | L | Scranton/Wilkes-Barre RailRiders 0 at Durham Bulls 4 | Final |
| April 20, 2025 | L | Scranton/Wilkes-Barre RailRiders 3 at Durham Bulls 4 | Final |
| April 22, 2025 | L | Charlotte Knights 5 at Scranton/Wilkes-Barre RailRiders 4 | Final (11) |
| April 23, 2025 | W | Charlotte Knights 0 at Scranton/Wilkes-Barre RailRiders 5 | Final |
| April 24, 2025 | L | Charlotte Knights 10 at Scranton/Wilkes-Barre RailRiders 3 | Final |
| April 25, 2025 | L | Charlotte Knights 4 at Scranton/Wilkes-Barre RailRiders 1 | Final (7) |
| April 26, 2025 | L | Charlotte Knights 8 at Scranton/Wilkes-Barre RailRiders 7 | Final |
| April 27, 2025 | L | Charlotte Knights 13 at Scranton/Wilkes-Barre RailRiders 12 | Final (12) |
| April 29, 2025 | | Scranton/Wilkes-Barre RailRiders at Syracuse Mets | Ppd. |
| April 30, 2025 | W | Scranton/Wilkes-Barre RailRiders 5 at Syracuse Mets 0 (Game 1) | Final (7) |
| April 30, 2025 | W | Scranton/Wilkes-Barre RailRiders 2 at Syracuse Mets 0 (Game 2) | Final (7) |
| May 1, 2025 | W | Scranton/Wilkes-Barre RailRiders 19 at Syracuse Mets 8 | Final |
| May 2, 2025 | L | Scranton/Wilkes-Barre RailRiders 3 at Syracuse Mets 6 | Final |
| May 3, 2025 | L | Scranton/Wilkes-Barre RailRiders 2 at Syracuse Mets 8 | Final |
| May 4, 2025 | W | Scranton/Wilkes-Barre RailRiders 4 at Syracuse Mets 2 | Final |
| May 6, 2025 | | Rochester Red Wings at Scranton/Wilkes-Barre RailRiders | Ppd. |
| May 7, 2025 | W | Rochester Red Wings 3 at Scranton/Wilkes-Barre RailRiders 5 (Game 1) | Final (7) |
| May 7, 2025 | L | Rochester Red Wings 8 at Scranton/Wilkes-Barre RailRiders 5 (Game 2) | Final (7) |
| May 8, 2025 | | Rochester Red Wings at Scranton/Wilkes-Barre RailRiders | Cancelled |
| May 9, 2025 | | Rochester Red Wings at Scranton/Wilkes-Barre RailRiders | Cancelled |
| May 10, 2025 | W | Rochester Red Wings 6 at Scranton/Wilkes-Barre RailRiders 7 (Game 1) | Final (8) |
| May 10, 2025 | L | Rochester Red Wings 5 at Scranton/Wilkes-Barre RailRiders 4 (Game 2) | Final (7) |
| May 11, 2025 | W | Rochester Red Wings 0 at Scranton/Wilkes-Barre RailRiders 12 | Final |
| May 13, 2025 | L | Toledo Mud Hens 7 at Scranton/Wilkes-Barre RailRiders 0 | Final |
| May 14, 2025 | W | Toledo Mud Hens 4 at Scranton/Wilkes-Barre RailRiders 5 | Final |
| May 15, 2025 | L | Toledo Mud Hens 20 at Scranton/Wilkes-Barre RailRiders 7 | Final |
| May 16, 2025 | L | Toledo Mud Hens 6 at Scranton/Wilkes-Barre RailRiders 3 | Final |
| May 17, 2025 | W | Toledo Mud Hens 2 at Scranton/Wilkes-Barre RailRiders 7 | Final |
| May 18, 2025 | L | Toledo Mud Hens 10 at Scranton/Wilkes-Barre RailRiders 8 | Final |
| May 20, 2025 | | Scranton/Wilkes-Barre RailRiders at Nashville Sounds | Ppd. |
| May 21, 2025 | L | Scranton/Wilkes-Barre RailRiders 0 at Nashville Sounds 3 (Game 1) | Final (7) |
| May 21, 2025 | L | Scranton/Wilkes-Barre RailRiders 1 at Nashville Sounds 2 (Game 2) | Final (7) |
| May 22, 2025 | L | Scranton/Wilkes-Barre RailRiders 6 at Nashville Sounds 7 | Final (11) |
| May 23, 2025 | W | Scranton/Wilkes-Barre RailRiders 10 at Nashville Sounds 5 | Final |
| May 24, 2025 | L | Scranton/Wilkes-Barre RailRiders 5 at Nashville Sounds 12 | Final |
| May 25, 2025 | | Scranton/Wilkes-Barre RailRiders at Nashville Sounds | Cancelled |
| May 27, 2025 | W | Worcester Red Sox 6 at Scranton/Wilkes-Barre RailRiders 11 | Final |
| May 28, 2025 | L | Worcester Red Sox 5 at Scranton/Wilkes-Barre RailRiders 4 | Final |
| May 29, 2025 | L | Worcester Red Sox 3 at Scranton/Wilkes-Barre RailRiders 2 | Final |
| May 30, 2025 | W | Worcester Red Sox 1 at Scranton/Wilkes-Barre RailRiders 3 | Final |
| May 31, 2025 | W | Worcester Red Sox 0 at Scranton/Wilkes-Barre RailRiders 3 | Final |
| June 1, 2025 | L | Worcester Red Sox 7 at Scranton/Wilkes-Barre RailRiders 4 | Final |
| June 3, 2025 | W | Scranton/Wilkes-Barre RailRiders 8 at St. Paul Saints 5 | Final |
| June 4, 2025 | L | Scranton/Wilkes-Barre RailRiders 5 at St. Paul Saints 7 | Final |
| June 5, 2025 | W | Scranton/Wilkes-Barre RailRiders 11 at St. Paul Saints 8 | Final |
| June 6, 2025 | W | Scranton/Wilkes-Barre RailRiders 5 at St. Paul Saints 1 | Final |
| June 7, 2025 | L | Scranton/Wilkes-Barre RailRiders 1 at St. Paul Saints 4 | Final |
| June 8, 2025 | W | Scranton/Wilkes-Barre RailRiders 7 at St. Paul Saints 2 | Final |
| June 10, 2025 | W | Syracuse Mets 3 at Scranton/Wilkes-Barre RailRiders 5 | Final |
| June 11, 2025 | W | Syracuse Mets 5 at Scranton/Wilkes-Barre RailRiders 7 | Final |
| June 12, 2025 | W | Syracuse Mets 1 at Scranton/Wilkes-Barre RailRiders 6 | Final |
| June 13, 2025 | W | Syracuse Mets 3 at Scranton/Wilkes-Barre RailRiders 10 | Final |
| June 14, 2025 | W | Syracuse Mets 1 at Scranton/Wilkes-Barre RailRiders 5 | Final |
| June 15, 2025 | W | Syracuse Mets 6 at Scranton/Wilkes-Barre RailRiders 8 | Final |
| June 17, 2025 | W | Scranton/Wilkes-Barre RailRiders 4 at Louisville Bats 3 | Final |
| June 18, 2025 | L | Scranton/Wilkes-Barre RailRiders 1 at Louisville Bats 8 | Final |
| June 19, 2025 | L | Scranton/Wilkes-Barre RailRiders 3 at Louisville Bats 6 | Final |
| June 20, 2025 | L | Scranton/Wilkes-Barre RailRiders 1 at Louisville Bats 5 | Final |
| June 21, 2025 | W | Scranton/Wilkes-Barre RailRiders 4 at Louisville Bats 3 | Final (10) |
| June 22, 2025 | W | Scranton/Wilkes-Barre RailRiders 3 at Louisville Bats 2 | Final |
| June 24, 2025 | W | Worcester Red Sox 5 at Scranton/Wilkes-Barre RailRiders 6 | Final |
| June 25, 2025 | W | Worcester Red Sox 0 at Scranton/Wilkes-Barre RailRiders 4 | Final |
| June 26, 2025 | W | Worcester Red Sox 2 at Scranton/Wilkes-Barre RailRiders 4 | Final |
| June 27, 2025 | W | Worcester Red Sox 2 at Scranton/Wilkes-Barre RailRiders 4 | Final |
| June 28, 2025 | L | Worcester Red Sox 5 at Scranton/Wilkes-Barre RailRiders 3 | Final (10) |
| June 29, 2025 | W | Worcester Red Sox 1 at Scranton/Wilkes-Barre RailRiders 6 | Final |
| July 1, 2025 | | Scranton/Wilkes-Barre RailRiders at Lehigh Valley IronPigs | Ppd. |
| July 2, 2025 | W | Scranton/Wilkes-Barre RailRiders 9 at Lehigh Valley IronPigs 8 | Final |
| July 3, 2025 | L | Scranton/Wilkes-Barre RailRiders 5 at Lehigh Valley IronPigs 6 | Final |
| July 4, 2025 | L | Lehigh Valley IronPigs 5 at Scranton/Wilkes-Barre RailRiders 4 | Final |
| July 5, 2025 | W | Lehigh Valley IronPigs 6 at Scranton/Wilkes-Barre RailRiders 16 | Final |
| July 6, 2025 | W | Lehigh Valley IronPigs 6 at Scranton/Wilkes-Barre RailRiders 9 | Final |
| July 8, 2025 | W | Buffalo Bisons 2 at Scranton/Wilkes-Barre RailRiders 5 | Final |
| July 9, 2025 | W | Buffalo Bisons 2 at Scranton/Wilkes-Barre RailRiders 7 | Final |
| July 10, 2025 | W | Buffalo Bisons 7 at Scranton/Wilkes-Barre RailRiders 11 | Final |
| July 11, 2025 | W | Buffalo Bisons 1 at Scranton/Wilkes-Barre RailRiders 10 | Final |
| July 12, 2025 | W | Buffalo Bisons 3 at Scranton/Wilkes-Barre RailRiders 6 | Final |
| July 13, 2025 | W | Buffalo Bisons 4 at Scranton/Wilkes-Barre RailRiders 5 | Final |
| July 18, 2025 | W | Scranton/Wilkes-Barre RailRiders 11 at Worcester Red Sox 3 | Final |
| July 19, 2025 | W | Scranton/Wilkes-Barre RailRiders 10 at Worcester Red Sox 8 | Final |
| July 20, 2025 | W | Scranton/Wilkes-Barre RailRiders 8 at Worcester Red Sox 2 | Final |
| July 22, 2025 | L | Scranton/Wilkes-Barre RailRiders 1 at Rochester Red Wings 7 | Final |
| July 23, 2025 | W | Scranton/Wilkes-Barre RailRiders 8 at Rochester Red Wings 6 | Final (12) |
| July 24, 2025 | L | Scranton/Wilkes-Barre RailRiders 8 at Rochester Red Wings 10 | Final |
| July 25, 2025 | W | Scranton/Wilkes-Barre RailRiders 7 at Rochester Red Wings 5 | Final |
| July 26, 2025 | W | Scranton/Wilkes-Barre RailRiders 6 at Rochester Red Wings 2 | Final |
| July 27, 2025 | W | Scranton/Wilkes-Barre RailRiders 8 at Rochester Red Wings 7 | Final |
| July 29, 2025 | L | Nashville Sounds 7 at Scranton/Wilkes-Barre RailRiders 3 | Final |
| July 30, 2025 | W | Nashville Sounds 0 at Scranton/Wilkes-Barre RailRiders 1 | Final |
| July 31, 2025 | | Nashville Sounds at Scranton/Wilkes-Barre RailRiders | Ppd. |
| August 1, 2025 | W | Nashville Sounds 0 at Scranton/Wilkes-Barre RailRiders 2 (Game 1) | Final (7) |
| August 1, 2025 | W | Nashville Sounds 3 at Scranton/Wilkes-Barre RailRiders 8 (Game 2) | Final (7) |
| August 2, 2025 | L | Nashville Sounds 7 at Scranton/Wilkes-Barre RailRiders 5 | Final |
| August 3, 2025 | W | Nashville Sounds 7 at Scranton/Wilkes-Barre RailRiders 8 | Final |
| August 5, 2025 | W | Scranton/Wilkes-Barre RailRiders 7 at Lehigh Valley IronPigs 1 | Final |
| August 6, 2025 | L | Scranton/Wilkes-Barre RailRiders 1 at Lehigh Valley IronPigs 12 (Game 1) | Final (7) |
| August 6, 2025 | W | Scranton/Wilkes-Barre RailRiders 12 at Lehigh Valley IronPigs 9 (Game 2) | Final |
| August 7, 2025 | W | Scranton/Wilkes-Barre RailRiders 4 at Lehigh Valley IronPigs 1 | Final |
| August 8, 2025 | L | Scranton/Wilkes-Barre RailRiders 5 at Lehigh Valley IronPigs 10 | Final |
| August 9, 2025 | L | Scranton/Wilkes-Barre RailRiders 0 at Lehigh Valley IronPigs 3 | Final |
| August 10, 2025 | W | Scranton/Wilkes-Barre RailRiders 9 at Lehigh Valley IronPigs 7 | Final |
| August 12, 2025 | L | Indianapolis Indians 6 at Scranton/Wilkes-Barre RailRiders 5 | Final |
| August 13, 2025 | W | Indianapolis Indians 5 at Scranton/Wilkes-Barre RailRiders 6 | Final |
| August 14, 2025 | L | Indianapolis Indians 9 at Scranton/Wilkes-Barre RailRiders 6 | Final |
| August 15, 2025 | L | Indianapolis Indians 6 at Scranton/Wilkes-Barre RailRiders 5 | Final (10) |
| August 16, 2025 | W | Indianapolis Indians 5 at Scranton/Wilkes-Barre RailRiders 11 | Final |
| August 17, 2025 | W | Indianapolis Indians 5 at Scranton/Wilkes-Barre RailRiders 7 | Final |
| August 19, 2025 | | Scranton/Wilkes-Barre RailRiders at Buffalo Bisons | Ppd. |
| August 20, 2025 | L | Scranton/Wilkes-Barre RailRiders 1 at Buffalo Bisons 4 | Final |
| August 21, 2025 | W | Scranton/Wilkes-Barre RailRiders 5 at Buffalo Bisons 3 (Game 1) | Final (7) |
| August 21, 2025 | L | Scranton/Wilkes-Barre RailRiders 3 at Buffalo Bisons 4 (Game 2) | Final |
| August 22, 2025 | W | Scranton/Wilkes-Barre RailRiders 7 at Buffalo Bisons 4 | Final |
| August 23, 2025 | W | Scranton/Wilkes-Barre RailRiders 10 at Buffalo Bisons 3 | Final |
| August 24, 2025 | W | Scranton/Wilkes-Barre RailRiders 5 at Buffalo Bisons 3 | Final |
| August 26, 2025 | W | Syracuse Mets 4 at Scranton/Wilkes-Barre RailRiders 9 | Final |
| August 27, 2025 | W | Syracuse Mets 1 at Scranton/Wilkes-Barre RailRiders 6 | Final |
| August 28, 2025 | L | Syracuse Mets 11 at Scranton/Wilkes-Barre RailRiders 8 | Final |
| August 29, 2025 | W | Syracuse Mets 2 at Scranton/Wilkes-Barre RailRiders 6 | Final |
| August 30, 2025 | L | Syracuse Mets 2 at Scranton/Wilkes-Barre RailRiders 0 | Final |
| August 31, 2025 | L | Syracuse Mets 3 at Scranton/Wilkes-Barre RailRiders 0 | Final |
| September 2, 2025 | W | Scranton/Wilkes-Barre RailRiders 8 at Worcester Red Sox 7 | Final |
| September 3, 2025 | W | Scranton/Wilkes-Barre RailRiders 5 at Worcester Red Sox 1 | Final |
| September 4, 2025 | W | Scranton/Wilkes-Barre RailRiders 6 at Worcester Red Sox 2 | Final |
| September 5, 2025 | L | Scranton/Wilkes-Barre RailRiders 4 at Worcester Red Sox 7 | Final |
| September 6, 2025 | | Scranton/Wilkes-Barre RailRiders at Worcester Red Sox | Ppd. |
| September 7, 2025 | L | Scranton/Wilkes-Barre RailRiders 5 at Worcester Red Sox 6 (Game 1) | Final (8) |
| September 7, 2025 | W | Scranton/Wilkes-Barre RailRiders 5 at Worcester Red Sox 0 (Game 2) | Final (7) |
| September 9, 2025 | L | Lehigh Valley IronPigs 5 at Scranton/Wilkes-Barre RailRiders 4 | Final |
| September 10, 2025 | L | Lehigh Valley IronPigs 4 at Scranton/Wilkes-Barre RailRiders 1 | Final |
| September 11, 2025 | W | Lehigh Valley IronPigs 2 at Scranton/Wilkes-Barre RailRiders 3 | Final |
| September 12, 2025 | L | Lehigh Valley IronPigs 9 at Scranton/Wilkes-Barre RailRiders 5 | Final |
| September 13, 2025 | W | Lehigh Valley IronPigs 5 at Scranton/Wilkes-Barre RailRiders 8 | Final |
| September 14, 2025 | L | Lehigh Valley IronPigs 6 at Scranton/Wilkes-Barre RailRiders 1 | Final |
| September 16, 2025 | W | Scranton/Wilkes-Barre RailRiders 3 at Buffalo Bisons 1 | Final |
| September 17, 2025 | W | Scranton/Wilkes-Barre RailRiders 6 at Buffalo Bisons 1 | Final |
| September 18, 2025 | L | Scranton/Wilkes-Barre RailRiders 0 at Buffalo Bisons 2 | Final |
| September 19, 2025 | W | Scranton/Wilkes-Barre RailRiders 10 at Buffalo Bisons 2 | Final |
| September 20, 2025 | L | Scranton/Wilkes-Barre RailRiders 2 at Buffalo Bisons 4 | Final |
| September 21, 2025 | W | Scranton/Wilkes-Barre RailRiders 2 at Buffalo Bisons 1 | Final |
| September 23, 2025 | W | Scranton/Wilkes-Barre RailRiders 5 at Jacksonville Jumbo Shrimp 4 (Champ. Gm. 1) | Final (10) |
| September 24, 2025 | L | Scranton/Wilkes-Barre RailRiders 4 at Jacksonville Jumbo Shrimp 6 (Champ. Gm. 2) | Final |
| September 25, 2025 | L | Scranton/Wilkes-Barre RailRiders 4 at Jacksonville Jumbo Shrimp 7 (Champ. Gm. 3) | Final |
Scranton/Wilkes-Barre RailRiders Schedule
