OKC Energy FC Schedule
All times Eastern
| April 24, 2021 | L | FC Tulsa 3 at OKC Energy FC 1 | Final |
| May 1, 2021 | L | Atlanta United 2 1 at OKC Energy FC 0 | Final |
| May 7, 2021 | T | OKC Energy FC 1 at Sporting Kansas City II 1 | Final |
| May 16, 2021 | T | Atlanta United 2 2 at OKC Energy FC 2 | Final |
| May 26, 2021 | L | OKC Energy FC 0 at Birmingham Legion FC 1 | Final |
| May 29, 2021 | T | Memphis 901 FC 0 at OKC Energy FC 0 | Final |
| June 2, 2021 | T | OKC Energy FC 1 at Indy Eleven 1 | Final |
| June 12, 2021 | L | Birmingham Legion FC 2 at OKC Energy FC 1 | Final |
| June 19, 2021 | W | OKC Energy FC 1 at Memphis 901 FC 0 | Final |
| June 23, 2021 | W | Sporting Kansas City II 0 at OKC Energy FC 1 | Final |
| June 27, 2021 | W | OKC Energy FC 2 at Atlanta United 2 1 | Final |
| July 2, 2021 | T | FC Tulsa 0 at OKC Energy FC 0 | Final |
| July 10, 2021 | Indy Eleven at OKC Energy FC | Ppd. | |
| July 14, 2021 | L | OKC Energy FC 1 at Louisville City FC 3 | Final |
| July 17, 2021 | W | OKC Energy FC 2 at FC Tulsa 1 | Final |
| July 24, 2021 | T | Sporting Kansas City II 0 at OKC Energy FC 0 | Final |
| July 31, 2021 | L | OKC Energy FC 1 at Louisville City FC 2 | Final |
| August 7, 2021 | W | Memphis 901 FC 1 at OKC Energy FC 4 | Final |
| August 11, 2021 | T | OKC Energy FC 2 at Atlanta United 2 2 | Final |
| August 14, 2021 | L | OKC Energy FC 1 at Indy Eleven 2 | Final |
| August 22, 2021 | T | Louisville City FC 0 at OKC Energy FC 0 | Final |
| August 29, 2021 | W | Rio Grande Valley FC Toros 1 at OKC Energy FC 2 | Final |
| September 1, 2021 | W | OKC Energy FC 1 at Memphis 901 FC 0 | Final |
| September 4, 2021 | L | OKC Energy FC 0 at Sporting Kansas City II 3 | Final |
| September 12, 2021 | T | Louisville City FC 1 at OKC Energy FC 1 | Final |
| September 18, 2021 | T | OKC Energy FC 1 at Birmingham Legion FC 1 | Final |
| September 26, 2021 | W | Indy Eleven 0 at OKC Energy FC 2 | Final |
| September 29, 2021 | T | Indy Eleven 1 at OKC Energy FC 1 | Final |
| October 3, 2021 | L | San Antonio FC 1 at OKC Energy FC 0 | Final |
| October 10, 2021 | T | OKC Energy FC 1 at Austin Bold FC 1 | Final |
| October 17, 2021 | T | Birmingham Legion FC 0 at OKC Energy FC 0 | Final |
| October 24, 2021 | L | OKC Energy FC 0 at El Paso Locomotive FC 4 | Final |
| October 30, 2021 | L | OKC Energy FC 0 at FC Tulsa 2 | Final |
