| | | |
| May 18, 2026 | L | Niagara River Lions 85 at Ottawa BlackJacks 91 | Final |
| May 22, 2026 | L | Niagara River Lions 71 at Winnipeg Sea Bears 97 | Final |
| May 24, 2026 | W | Niagara River Lions 101 at Edmonton Stingers 99 | Final |
| May 26, 2026 | W | Niagara River Lions 87 at Montreal Alliance 72 | Final |
| May 29, 2026 | L | Vancouver Bandits 110 at Niagara River Lions 100 | Final |
| June 3, 2026 | W | Calgary Surge 76 at Niagara River Lions 88 | Final |
| June 5, 2026 | L | Brampton Honey Badgers 97 at Niagara River Lions 86 | Final |
| June 10, 2026 | L | Scarborough Shooting Stars 104 at Niagara River Lions 93 | Final |
| June 13, 2026 | W | Montreal Alliance 75 at Niagara River Lions 93 | Final |
| June 15, 2026 | W | Niagara River Lions 101 at Brampton Honey Badgers 84 | Final |
| June 19, 2026 | L | Saskatoon Mamba 104 at Niagara River Lions 77 | Final |
| June 21, 2026 | L | Niagara River Lions 69 at Scarborough Shooting Stars 75 | Final |
| June 26, 2026 | L | Niagara River Lions 86 at Montreal Alliance 96 | Final |
| June 28, 2026 | L | Niagara River Lions 69 at Ottawa BlackJacks 92 | Final |
| July 4, 2026 | L | Ottawa BlackJacks 86 at Niagara River Lions 77 | Final |
| July 10, 2026 | W | Scarborough Shooting Stars 89 at Niagara River Lions 98 | Final |
| July 12, 2026 | W | Montreal Alliance 87 at Niagara River Lions 90 | Final |
| July 14, 2026 | W | Niagara River Lions 91 at Brampton Honey Badgers 81 | Final |
| July 16, 2026 | W | Brampton Honey Badgers 90 at Niagara River Lions 99 | Final |
| July 18, 2026 | L | Edmonton Stingers 102 at Niagara River Lions 91 | Final |
| July 24, 2026 | L | Niagara River Lions 75 at Scarborough Shooting Stars 82 | Final |
| July 26, 2026 | W | Ottawa BlackJacks 102 at Niagara River Lions 106 | Final |
| July 29, 2026 | L | Niagara River Lions 83 at Saskatoon Mamba 94 | Final |
| July 31, 2026 | L | Niagara River Lions 76 at Calgary Surge 81 | Final |
| August 6, 2026 | W | Niagara River Lions 86 at Scarborough Shooting Stars 84 (Playoff) | Final |
| August 8, 2026 | L | Niagara River Lions 81 at Brampton Honey Badgers 91 (Playoff) | Final |
Niagara River Lions Schedule
