| | | |
| March 7, 2025 | L | Chattanooga FC 2 at Inter Miami CF II 1 | Final |
| March 13, 2025 | T | Carolina Core FC 1 at Inter Miami CF II 1 | Final (PK 4-2) |
| March 23, 2025 | W | Columbus Crew 2 2 at Inter Miami CF II 4 | Final |
| April 6, 2025 | | Inter Miami CF II 1 at Atlanta United 2 1 | Susp. |
| April 7, 2025 | L | Inter Miami CF II 2 at Atlanta United 2 3 | Final |
| April 10, 2025 | L | Toronto FC II 1 at Inter Miami CF II 0 | Final |
| April 15, 2025 | W | Orlando City B 2 at Inter Miami CF II 3 | Final |
| April 27, 2025 | L | Inter Miami CF II 0 at Huntsville City Football Club 4 | Final |
| May 4, 2025 | | New York City FC II at Inter Miami CF II | 7:00 p.m. |
| May 9, 2025 | | Inter Miami CF II at Crown Legacy FC | 7:00 p.m. |
| May 17, 2025 | | Inter Miami CF II at Orlando City B | 7:00 p.m. |
| May 25, 2025 | | Inter Miami CF II at Philadelphia Union II | 3:00 p.m. |
| June 1, 2025 | | Carolina Core FC at Inter Miami CF II | 7:00 p.m. |
| June 7, 2025 | | Inter Miami CF II at Chattanooga FC | 7:00 p.m. |
| June 12, 2025 | | Inter Miami CF II at Toronto FC II | 7:00 p.m. |
| June 25, 2025 | | Chicago Fire FC II at Inter Miami CF II | 7:00 p.m. |
| June 29, 2025 | | Atlanta United 2 at Inter Miami CF II | 7:00 p.m. |
| July 4, 2025 | | Inter Miami CF II at Carolina Core FC | 7:30 p.m. |
| July 13, 2025 | | Crown Legacy FC at Inter Miami CF II | 7:00 p.m. |
| July 19, 2025 | | Inter Miami CF II at Chattanooga FC | 7:00 p.m. |
| July 27, 2025 | | FC Cincinnati 2 at Inter Miami CF II | 7:00 p.m. |
| August 14, 2025 | | Huntsville City Football Club at Inter Miami CF II | 7:00 p.m. |
| August 22, 2025 | | Inter Miami CF II at Crown Legacy FC | 7:00 p.m. |
| August 27, 2025 | | Inter Miami CF II at Atlanta United 2 | 7:30 p.m. |
| September 7, 2025 | | Inter Miami CF II at Columbus Crew 2 | 3:00 p.m. |
| September 14, 2025 | | Orlando City B at Inter Miami CF II | 7:00 p.m. |
| September 21, 2025 | | Inter Miami CF II at New York Red Bulls II | 5:00 p.m. |
| September 28, 2025 | | Inter Miami CF II at Huntsville City Football Club | 8:00 p.m. |
| October 5, 2025 | | New England Revolution II at Inter Miami CF II | 1:00 p.m. |
Inter Miami CF II Schedule
