| | | |
| April 4, 2025 | L | Fort Myers Mighty Mussels 2 at Palm Beach Cardinals 8 | Final |
| April 5, 2025 | W | Fort Myers Mighty Mussels 6 at Palm Beach Cardinals 4 | Final |
| April 6, 2025 | L | Fort Myers Mighty Mussels 10 at Palm Beach Cardinals 11 | Final |
| April 8, 2025 | L | Tampa Tarpons 5 at Fort Myers Mighty Mussels 3 | Final |
| April 9, 2025 | W | Tampa Tarpons 1 at Fort Myers Mighty Mussels 5 | Final |
| April 10, 2025 | L | Tampa Tarpons 4 at Fort Myers Mighty Mussels 1 | Final |
| April 11, 2025 | W | Tampa Tarpons 3 at Fort Myers Mighty Mussels 6 | Final |
| April 12, 2025 | W | Tampa Tarpons 1 at Fort Myers Mighty Mussels 2 | Final |
| April 13, 2025 | L | Tampa Tarpons 4 at Fort Myers Mighty Mussels 2 | Final |
| April 15, 2025 | W | Bradenton Marauders 4 at Fort Myers Mighty Mussels 9 | Final |
| April 16, 2025 | W | Bradenton Marauders 0 at Fort Myers Mighty Mussels 1 | Final |
| April 17, 2025 | L | Bradenton Marauders 6 at Fort Myers Mighty Mussels 3 | Final |
| April 18, 2025 | L | Bradenton Marauders 6 at Fort Myers Mighty Mussels 1 | Final |
| April 19, 2025 | W | Bradenton Marauders 0 at Fort Myers Mighty Mussels 8 | Final |
| April 20, 2025 | W | Bradenton Marauders 0 at Fort Myers Mighty Mussels 1 | Final |
| April 22, 2025 | W | Fort Myers Mighty Mussels 8 at Clearwater Threshers 3 | Final |
| April 23, 2025 | L | Fort Myers Mighty Mussels 3 at Clearwater Threshers 4 | Final |
| April 24, 2025 | W | Fort Myers Mighty Mussels 5 at Clearwater Threshers 3 | Final (10) |
| April 25, 2025 | L | Fort Myers Mighty Mussels 3 at Clearwater Threshers 4 | Final |
| April 26, 2025 | W | Fort Myers Mighty Mussels 5 at Clearwater Threshers 3 | Final |
| April 27, 2025 | W | Fort Myers Mighty Mussels 10 at Clearwater Threshers 1 | Final |
| April 29, 2025 | L | Jupiter Hammerheads 14 at Fort Myers Mighty Mussels 1 | Final |
| April 30, 2025 | W | Jupiter Hammerheads 5 at Fort Myers Mighty Mussels 6 | Final |
| May 1, 2025 | L | Jupiter Hammerheads 5 at Fort Myers Mighty Mussels 1 | Final |
| May 2, 2025 | W | Fort Myers Mighty Mussels 9 at Tampa Tarpons 2 | Final |
| May 3, 2025 | L | Fort Myers Mighty Mussels 5 at Tampa Tarpons 12 | Final |
| May 4, 2025 | L | Fort Myers Mighty Mussels 4 at Tampa Tarpons 12 | Final |
| May 6, 2025 | W | Dunedin Blue Jays 12 at Fort Myers Mighty Mussels 13 | Final (11) |
| May 7, 2025 | L | Dunedin Blue Jays 7 at Fort Myers Mighty Mussels 3 | Final |
| May 8, 2025 | L | Dunedin Blue Jays 5 at Fort Myers Mighty Mussels 4 | Final |
| May 9, 2025 | L | Dunedin Blue Jays 9 at Fort Myers Mighty Mussels 1 | Final |
| May 10, 2025 | L | Dunedin Blue Jays 3 at Fort Myers Mighty Mussels 0 | Final |
| May 11, 2025 | L | Dunedin Blue Jays 7 at Fort Myers Mighty Mussels 4 | Final |
| May 13, 2025 | L | Fort Myers Mighty Mussels 4 at Jupiter Hammerheads 5 | Final |
| May 14, 2025 | W | Fort Myers Mighty Mussels 4 at Jupiter Hammerheads 3 | Final (10) |
| May 15, 2025 | L | Fort Myers Mighty Mussels 6 at Jupiter Hammerheads 12 | Final |
| May 16, 2025 | W | Fort Myers Mighty Mussels 9 at Jupiter Hammerheads 4 | Final |
| May 17, 2025 | W | Fort Myers Mighty Mussels 6 at Jupiter Hammerheads 5 | Final (12) |
| May 18, 2025 | W | Fort Myers Mighty Mussels 8 at Jupiter Hammerheads 4 | Final |
| May 20, 2025 | L | Fort Myers Mighty Mussels 3 at Lakeland Flying Tigers 13 | Final |
| May 21, 2025 | L | Fort Myers Mighty Mussels 3 at Lakeland Flying Tigers 5 | Final |
| May 22, 2025 | L | Fort Myers Mighty Mussels 1 at Lakeland Flying Tigers 4 | Final |
| May 23, 2025 | L | Fort Myers Mighty Mussels 3 at Lakeland Flying Tigers 6 | Final |
| May 24, 2025 | W | Fort Myers Mighty Mussels 5 at Lakeland Flying Tigers 4 | Final (10) |
| May 25, 2025 | L | Fort Myers Mighty Mussels 12 at Lakeland Flying Tigers 15 | Final |
| May 27, 2025 | W | Bradenton Marauders 3 at Fort Myers Mighty Mussels 6 | Final |
| May 28, 2025 | L | Bradenton Marauders 8 at Fort Myers Mighty Mussels 5 | Final |
| May 29, 2025 | L | Bradenton Marauders 6 at Fort Myers Mighty Mussels 4 | Final |
| May 30, 2025 | L | Fort Myers Mighty Mussels 3 at Tampa Tarpons 9 | Final |
| May 31, 2025 | W | Fort Myers Mighty Mussels 11 at Tampa Tarpons 1 | Final |
| June 1, 2025 | W | Fort Myers Mighty Mussels 3 at Tampa Tarpons 2 | Final |
| June 3, 2025 | W | Palm Beach Cardinals 3 at Fort Myers Mighty Mussels 4 | Final |
| June 4, 2025 | L | Palm Beach Cardinals 8 at Fort Myers Mighty Mussels 1 | Final |
| June 5, 2025 | L | Palm Beach Cardinals 2 at Fort Myers Mighty Mussels 1 | Final |
| June 6, 2025 | W | Palm Beach Cardinals 2 at Fort Myers Mighty Mussels 6 | Final |
| June 7, 2025 | W | Palm Beach Cardinals 1 at Fort Myers Mighty Mussels 3 | Final |
| June 8, 2025 | L | Palm Beach Cardinals 4 at Fort Myers Mighty Mussels 0 | Final |
| June 10, 2025 | W | Fort Myers Mighty Mussels 5 at Dunedin Blue Jays 4 | Final |
| June 11, 2025 | | Fort Myers Mighty Mussels at Dunedin Blue Jays | Ppd. |
| June 12, 2025 | | Fort Myers Mighty Mussels at Dunedin Blue Jays (Game 2) | Ppd. |
| June 12, 2025 | | Fort Myers Mighty Mussels at Dunedin Blue Jays (Game 1) | Susp. |
| June 13, 2025 | L | Fort Myers Mighty Mussels 2 at Dunedin Blue Jays 3 (Game 1) | Final (7) |
| June 13, 2025 | L | Fort Myers Mighty Mussels 0 at Dunedin Blue Jays 1 (Game 2) | Final (7) |
| June 14, 2025 | L | Fort Myers Mighty Mussels 7 at Dunedin Blue Jays 8 | Final (11) |
| June 15, 2025 | | Fort Myers Mighty Mussels at Dunedin Blue Jays (Game 2) | Cancelled |
| June 15, 2025 | L | Fort Myers Mighty Mussels 0 at Dunedin Blue Jays 3 (Game 1) | Final (5) |
| June 17, 2025 | | Lakeland Flying Tigers at Fort Myers Mighty Mussels | Susp. |
| June 18, 2025 | L | Lakeland Flying Tigers 5 at Fort Myers Mighty Mussels 2 (Game 1) | Final |
| June 18, 2025 | L | Lakeland Flying Tigers 6 at Fort Myers Mighty Mussels 1 (Game 2) | Final (7) |
| June 19, 2025 | | Lakeland Flying Tigers at Fort Myers Mighty Mussels | Cancelled |
| June 20, 2025 | W | Lakeland Flying Tigers 5 at Fort Myers Mighty Mussels 6 | Final |
| June 21, 2025 | W | Lakeland Flying Tigers 2 at Fort Myers Mighty Mussels 5 | Final |
| June 22, 2025 | L | Lakeland Flying Tigers 8 at Fort Myers Mighty Mussels 4 | Final |
| June 24, 2025 | L | Fort Myers Mighty Mussels 3 at Tampa Tarpons 6 | Final |
| June 25, 2025 | W | Fort Myers Mighty Mussels 3 at Tampa Tarpons 1 | Final |
| June 26, 2025 | W | Fort Myers Mighty Mussels 12 at Tampa Tarpons 7 | Final |
| June 27, 2025 | L | Fort Myers Mighty Mussels 3 at Tampa Tarpons 5 | Final |
| June 28, 2025 | L | Fort Myers Mighty Mussels 4 at Tampa Tarpons 7 | Final |
| June 29, 2025 | L | Fort Myers Mighty Mussels 1 at Tampa Tarpons 3 | Final |
| July 1, 2025 | L | Fort Myers Mighty Mussels 3 at Bradenton Marauders 4 | Final |
| July 2, 2025 | L | Fort Myers Mighty Mussels 1 at Bradenton Marauders 2 | Final |
| July 3, 2025 | W | Fort Myers Mighty Mussels 9 at Bradenton Marauders 2 | Final |
| July 4, 2025 | L | Bradenton Marauders 14 at Fort Myers Mighty Mussels 1 | Final |
| July 5, 2025 | L | Bradenton Marauders 5 at Fort Myers Mighty Mussels 3 | Final |
| July 6, 2025 | W | Bradenton Marauders 5 at Fort Myers Mighty Mussels 7 | Final |
| July 8, 2025 | W | Fort Myers Mighty Mussels 7 at Clearwater Threshers 1 | Final |
| July 9, 2025 | L | Fort Myers Mighty Mussels 2 at Clearwater Threshers 3 | Final |
| July 10, 2025 | L | Fort Myers Mighty Mussels 4 at Clearwater Threshers 7 | Final |
| July 11, 2025 | W | Fort Myers Mighty Mussels 4 at Clearwater Threshers 1 | Final |
| July 12, 2025 | W | Fort Myers Mighty Mussels 7 at Clearwater Threshers 2 | Final |
| July 13, 2025 | L | Fort Myers Mighty Mussels 0 at Clearwater Threshers 7 | Final |
| July 18, 2025 | W | Daytona Tortugas 6 at Fort Myers Mighty Mussels 8 | Final |
| July 19, 2025 | W | Daytona Tortugas 4 at Fort Myers Mighty Mussels 5 | Final (10) |
| July 20, 2025 | W | Daytona Tortugas 3 at Fort Myers Mighty Mussels 9 | Final |
| July 22, 2025 | L | Fort Myers Mighty Mussels 3 at Lakeland Flying Tigers 7 | Final |
| July 23, 2025 | L | Fort Myers Mighty Mussels 1 at Lakeland Flying Tigers 4 | Final |
| July 24, 2025 | W | Fort Myers Mighty Mussels 5 at Lakeland Flying Tigers 4 | Final (10) |
| July 25, 2025 | W | Lakeland Flying Tigers 6 at Fort Myers Mighty Mussels 8 | Final |
| July 26, 2025 | W | Lakeland Flying Tigers 0 at Fort Myers Mighty Mussels 6 | Final |
| July 27, 2025 | L | Lakeland Flying Tigers 2 at Fort Myers Mighty Mussels 0 | Final |
| July 29, 2025 | W | Fort Myers Mighty Mussels 6 at Bradenton Marauders 4 | Final (10) |
| July 30, 2025 | L | Fort Myers Mighty Mussels 3 at Bradenton Marauders 4 | Final |
| July 31, 2025 | L | Fort Myers Mighty Mussels 3 at Bradenton Marauders 5 | Final |
| August 1, 2025 | W | Dunedin Blue Jays 0 at Fort Myers Mighty Mussels 4 | Final |
| August 2, 2025 | W | Dunedin Blue Jays 2 at Fort Myers Mighty Mussels 3 | Final (10) |
| August 3, 2025 | L | Dunedin Blue Jays 7 at Fort Myers Mighty Mussels 1 | Final (11) |
| August 5, 2025 | L | Clearwater Threshers 7 at Fort Myers Mighty Mussels 6 | Final (10) |
| August 6, 2025 | L | Clearwater Threshers 6 at Fort Myers Mighty Mussels 4 | Final |
| August 7, 2025 | L | Clearwater Threshers 7 at Fort Myers Mighty Mussels 6 | Final |
| August 8, 2025 | | Clearwater Threshers at Fort Myers Mighty Mussels | 7:05 p.m. |
| August 9, 2025 | | Clearwater Threshers at Fort Myers Mighty Mussels | 6:05 p.m. |
| August 10, 2025 | | Clearwater Threshers at Fort Myers Mighty Mussels | 12:05 p.m. |
| August 12, 2025 | | Fort Myers Mighty Mussels at Daytona Tortugas | 6:35 p.m. |
| August 13, 2025 | | Fort Myers Mighty Mussels at Daytona Tortugas | 6:35 p.m. |
| August 14, 2025 | | Fort Myers Mighty Mussels at Daytona Tortugas | 6:35 p.m. |
| August 15, 2025 | | Fort Myers Mighty Mussels at Daytona Tortugas | 6:35 p.m. |
| August 16, 2025 | | Fort Myers Mighty Mussels at Daytona Tortugas | 6:35 p.m. |
| August 17, 2025 | | Fort Myers Mighty Mussels at Daytona Tortugas | 5:00 p.m. |
| August 19, 2025 | | Tampa Tarpons at Fort Myers Mighty Mussels | 7:05 p.m. |
| August 20, 2025 | | Tampa Tarpons at Fort Myers Mighty Mussels | 7:05 p.m. |
| August 21, 2025 | | Tampa Tarpons at Fort Myers Mighty Mussels | 7:05 p.m. |
| August 22, 2025 | | Tampa Tarpons at Fort Myers Mighty Mussels | 7:05 p.m. |
| August 23, 2025 | | Tampa Tarpons at Fort Myers Mighty Mussels | 6:05 p.m. |
| August 24, 2025 | | Tampa Tarpons at Fort Myers Mighty Mussels | 12:05 p.m. |
| August 26, 2025 | | Fort Myers Mighty Mussels at Dunedin Blue Jays | 6:30 p.m. |
| August 27, 2025 | | Fort Myers Mighty Mussels at Dunedin Blue Jays | 6:30 p.m. |
| August 28, 2025 | | Fort Myers Mighty Mussels at Dunedin Blue Jays | 6:30 p.m. |
| August 29, 2025 | | Fort Myers Mighty Mussels at Dunedin Blue Jays | 6:30 p.m. |
| August 30, 2025 | | Fort Myers Mighty Mussels at Dunedin Blue Jays | 6:30 p.m. |
| August 31, 2025 | | Fort Myers Mighty Mussels at Dunedin Blue Jays | 12:00 p.m. |
| September 2, 2025 | | St. Lucie Mets at Fort Myers Mighty Mussels | 7:05 p.m. |
| September 3, 2025 | | St. Lucie Mets at Fort Myers Mighty Mussels | 7:05 p.m. |
| September 4, 2025 | | St. Lucie Mets at Fort Myers Mighty Mussels | 7:05 p.m. |
| September 5, 2025 | | St. Lucie Mets at Fort Myers Mighty Mussels | 7:05 p.m. |
| September 6, 2025 | | St. Lucie Mets at Fort Myers Mighty Mussels | 6:05 p.m. |
| September 7, 2025 | | St. Lucie Mets at Fort Myers Mighty Mussels | 12:05 p.m. |
Fort Myers Mighty Mussels Schedule
