| | | |
| March 27, 2026 | L | Scranton/Wilkes-Barre RailRiders 8 at Buffalo Bisons 0 | Final |
| March 28, 2026 | | Scranton/Wilkes-Barre RailRiders at Buffalo Bisons | Ppd. |
| March 29, 2026 | L | Scranton/Wilkes-Barre RailRiders 5 at Buffalo Bisons 4 (Game 1) | Final (10) |
| March 29, 2026 | W | Scranton/Wilkes-Barre RailRiders 3 at Buffalo Bisons 7 (Game 2) | Final (7) |
| March 31, 2026 | W | Buffalo Bisons 6 at Omaha Storm Chasers 4 | Final |
| April 1, 2026 | L | Buffalo Bisons 0 at Omaha Storm Chasers 3 | Final |
| April 2, 2026 | L | Buffalo Bisons 7 at Omaha Storm Chasers 9 | Final |
| April 3, 2026 | | Buffalo Bisons at Omaha Storm Chasers | Ppd. |
| April 4, 2026 | | Buffalo Bisons at Omaha Storm Chasers | 3:05 p.m. |
| April 5, 2026 | | Buffalo Bisons at Omaha Storm Chasers | 3:05 p.m. |
| April 7, 2026 | | Syracuse Mets at Buffalo Bisons | 1:05 p.m. |
| April 8, 2026 | | Syracuse Mets at Buffalo Bisons | 1:05 p.m. |
| April 9, 2026 | | Syracuse Mets at Buffalo Bisons | 1:05 p.m. |
| April 10, 2026 | | Syracuse Mets at Buffalo Bisons | 1:05 p.m. |
| April 11, 2026 | | Syracuse Mets at Buffalo Bisons | 1:05 p.m. |
| April 12, 2026 | | Syracuse Mets at Buffalo Bisons | 1:05 p.m. |
| April 14, 2026 | | Buffalo Bisons at Rochester Red Wings | 6:05 p.m. |
| April 15, 2026 | | Buffalo Bisons at Rochester Red Wings | 1:05 p.m. |
| April 16, 2026 | | Buffalo Bisons at Rochester Red Wings | 6:05 p.m. |
| April 17, 2026 | | Buffalo Bisons at Rochester Red Wings | 6:05 p.m. |
| April 18, 2026 | | Buffalo Bisons at Rochester Red Wings | 1:05 p.m. |
| April 19, 2026 | | Buffalo Bisons at Rochester Red Wings | 1:05 p.m. |
| April 21, 2026 | | Columbus Clippers at Buffalo Bisons | 6:05 p.m. |
| April 22, 2026 | | Columbus Clippers at Buffalo Bisons | 6:05 p.m. |
| April 23, 2026 | | Columbus Clippers at Buffalo Bisons | 6:05 p.m. |
| April 24, 2026 | | Columbus Clippers at Buffalo Bisons | 6:05 p.m. |
| April 25, 2026 | | Columbus Clippers at Buffalo Bisons | 1:05 p.m. |
| April 26, 2026 | | Columbus Clippers at Buffalo Bisons | 1:05 p.m. |
| April 28, 2026 | | Buffalo Bisons at Scranton/Wilkes-Barre RailRiders | 6:35 p.m. |
| April 29, 2026 | | Buffalo Bisons at Scranton/Wilkes-Barre RailRiders | 6:35 p.m. |
| April 30, 2026 | | Buffalo Bisons at Scranton/Wilkes-Barre RailRiders | 6:35 p.m. |
| May 1, 2026 | | Buffalo Bisons at Scranton/Wilkes-Barre RailRiders | 6:35 p.m. |
| May 2, 2026 | | Buffalo Bisons at Scranton/Wilkes-Barre RailRiders | 3:05 p.m. |
| May 3, 2026 | | Buffalo Bisons at Scranton/Wilkes-Barre RailRiders | 1:35 p.m. |
| May 5, 2026 | | Buffalo Bisons at Lehigh Valley IronPigs | 11:00 a.m. |
| May 6, 2026 | | Buffalo Bisons at Lehigh Valley IronPigs | 6:45 p.m. |
| May 7, 2026 | | Buffalo Bisons at Lehigh Valley IronPigs | 6:45 p.m. |
| May 8, 2026 | | Buffalo Bisons at Lehigh Valley IronPigs | 6:45 p.m. |
| May 9, 2026 | | Buffalo Bisons at Lehigh Valley IronPigs | 6:35 p.m. |
| May 10, 2026 | | Buffalo Bisons at Lehigh Valley IronPigs | 1:15 p.m. |
| May 12, 2026 | | Worcester Red Sox at Buffalo Bisons | 6:05 p.m. |
| May 13, 2026 | | Worcester Red Sox at Buffalo Bisons | 6:05 p.m. |
| May 14, 2026 | | Worcester Red Sox at Buffalo Bisons | 6:05 p.m. |
| May 15, 2026 | | Worcester Red Sox at Buffalo Bisons | 6:05 p.m. |
| May 16, 2026 | | Worcester Red Sox at Buffalo Bisons | 1:05 p.m. |
| May 17, 2026 | | Worcester Red Sox at Buffalo Bisons | 1:05 p.m. |
| May 19, 2026 | | Buffalo Bisons at Syracuse Mets | 6:05 p.m. |
| May 20, 2026 | | Buffalo Bisons at Syracuse Mets | 11:05 a.m. |
| May 21, 2026 | | Buffalo Bisons at Syracuse Mets | 6:35 p.m. |
| May 22, 2026 | | Buffalo Bisons at Syracuse Mets | 6:35 p.m. |
| May 23, 2026 | | Buffalo Bisons at Syracuse Mets | 6:35 p.m. |
| May 24, 2026 | | Buffalo Bisons at Syracuse Mets | 6:35 p.m. |
| May 26, 2026 | | Lehigh Valley IronPigs at Buffalo Bisons | 6:05 p.m. |
| May 27, 2026 | | Lehigh Valley IronPigs at Buffalo Bisons | 1:05 p.m. |
| May 28, 2026 | | Lehigh Valley IronPigs at Buffalo Bisons | 11:05 a.m. |
| May 29, 2026 | | Lehigh Valley IronPigs at Buffalo Bisons | 6:05 p.m. |
| May 30, 2026 | | Lehigh Valley IronPigs at Buffalo Bisons | 1:05 p.m. |
| May 31, 2026 | | Lehigh Valley IronPigs at Buffalo Bisons | 1:05 p.m. |
| June 2, 2026 | | Buffalo Bisons at Worcester Red Sox | 6:05 p.m. |
| June 3, 2026 | | Buffalo Bisons at Worcester Red Sox | 11:05 a.m. |
| June 4, 2026 | | Buffalo Bisons at Worcester Red Sox | 6:05 p.m. |
| June 5, 2026 | | Buffalo Bisons at Worcester Red Sox | 6:05 p.m. |
| June 6, 2026 | | Buffalo Bisons at Worcester Red Sox | 4:05 p.m. |
| June 7, 2026 | | Buffalo Bisons at Worcester Red Sox | 1:05 p.m. |
| June 9, 2026 | | Syracuse Mets at Buffalo Bisons | 6:35 p.m. |
| June 10, 2026 | | Syracuse Mets at Buffalo Bisons | 6:35 p.m. |
| June 11, 2026 | | Syracuse Mets at Buffalo Bisons | 6:35 p.m. |
| June 12, 2026 | | Syracuse Mets at Buffalo Bisons | 6:35 p.m. |
| June 13, 2026 | | Syracuse Mets at Buffalo Bisons | 6:05 p.m. |
| June 14, 2026 | | Syracuse Mets at Buffalo Bisons | 1:05 p.m. |
| June 16, 2026 | | Charlotte Knights at Buffalo Bisons | 6:35 p.m. |
| June 17, 2026 | | Charlotte Knights at Buffalo Bisons | 1:05 p.m. |
| June 18, 2026 | | Charlotte Knights at Buffalo Bisons | 6:35 p.m. |
| June 19, 2026 | | Charlotte Knights at Buffalo Bisons | 6:35 p.m. |
| June 20, 2026 | | Charlotte Knights at Buffalo Bisons | 6:35 p.m. |
| June 21, 2026 | | Charlotte Knights at Buffalo Bisons | 1:05 p.m. |
| June 23, 2026 | | Buffalo Bisons at Iowa Cubs | 7:38 p.m. |
| June 24, 2026 | | Buffalo Bisons at Iowa Cubs | 1:08 p.m. |
| June 25, 2026 | | Buffalo Bisons at Iowa Cubs | 7:38 p.m. |
| June 26, 2026 | | Buffalo Bisons at Iowa Cubs | 8:08 p.m. |
| June 27, 2026 | | Buffalo Bisons at Iowa Cubs | 7:08 p.m. |
| June 28, 2026 | | Buffalo Bisons at Iowa Cubs | 2:08 p.m. |
| June 30, 2026 | | Buffalo Bisons at St. Paul Saints | 8:07 p.m. |
| July 1, 2026 | | Buffalo Bisons at St. Paul Saints | 8:07 p.m. |
| July 2, 2026 | | Buffalo Bisons at St. Paul Saints | 8:07 p.m. |
| July 3, 2026 | | Buffalo Bisons at St. Paul Saints | 7:07 p.m. |
| July 4, 2026 | | Buffalo Bisons at St. Paul Saints | 7:07 p.m. |
| July 5, 2026 | | Buffalo Bisons at St. Paul Saints | 3:07 p.m. |
| July 7, 2026 | | Scranton/Wilkes-Barre RailRiders at Buffalo Bisons | 6:35 p.m. |
| July 8, 2026 | | Scranton/Wilkes-Barre RailRiders at Buffalo Bisons | 6:35 p.m. |
| July 9, 2026 | | Scranton/Wilkes-Barre RailRiders at Buffalo Bisons | 6:35 p.m. |
| July 10, 2026 | | Scranton/Wilkes-Barre RailRiders at Buffalo Bisons | 6:35 p.m. |
| July 11, 2026 | | Scranton/Wilkes-Barre RailRiders at Buffalo Bisons | 6:35 p.m. |
| July 12, 2026 | | Scranton/Wilkes-Barre RailRiders at Buffalo Bisons | 1:05 p.m. |
| July 17, 2026 | | Buffalo Bisons at Syracuse Mets | 6:35 p.m. |
| July 18, 2026 | | Buffalo Bisons at Syracuse Mets | 6:35 p.m. |
| July 19, 2026 | | Buffalo Bisons at Syracuse Mets | 1:05 p.m. |
| July 21, 2026 | | Rochester Red Wings at Buffalo Bisons | 6:35 p.m. |
| July 22, 2026 | | Rochester Red Wings at Buffalo Bisons | 1:05 p.m. |
| July 23, 2026 | | Rochester Red Wings at Buffalo Bisons | 6:35 p.m. |
| July 24, 2026 | | Rochester Red Wings at Buffalo Bisons | 6:35 p.m. |
| July 25, 2026 | | Rochester Red Wings at Buffalo Bisons | 6:35 p.m. |
| July 26, 2026 | | Rochester Red Wings at Buffalo Bisons | 1:05 p.m. |
| July 28, 2026 | | Buffalo Bisons at Lehigh Valley IronPigs | 6:45 p.m. |
| July 29, 2026 | | Buffalo Bisons at Lehigh Valley IronPigs | 6:45 p.m. |
| July 30, 2026 | | Buffalo Bisons at Lehigh Valley IronPigs | 6:45 p.m. |
| July 31, 2026 | | Buffalo Bisons at Lehigh Valley IronPigs | 6:45 p.m. |
| August 1, 2026 | | Buffalo Bisons at Lehigh Valley IronPigs | 6:35 p.m. |
| August 2, 2026 | | Buffalo Bisons at Lehigh Valley IronPigs | 1:15 p.m. |
| August 4, 2026 | | Norfolk Tides at Buffalo Bisons | 6:35 p.m. |
| August 5, 2026 | | Norfolk Tides at Buffalo Bisons | 1:05 p.m. |
| August 6, 2026 | | Norfolk Tides at Buffalo Bisons | 6:35 p.m. |
| August 7, 2026 | | Norfolk Tides at Buffalo Bisons | 6:35 p.m. |
| August 8, 2026 | | Norfolk Tides at Buffalo Bisons | 6:35 p.m. |
| August 9, 2026 | | Norfolk Tides at Buffalo Bisons | 1:05 p.m. |
| August 11, 2026 | | Buffalo Bisons at Worcester Red Sox | 6:45 p.m. |
| August 12, 2026 | | Buffalo Bisons at Worcester Red Sox | 12:05 p.m. |
| August 13, 2026 | | Buffalo Bisons at Worcester Red Sox | 6:45 p.m. |
| August 14, 2026 | | Buffalo Bisons at Worcester Red Sox | 6:45 p.m. |
| August 15, 2026 | | Buffalo Bisons at Worcester Red Sox | 4:05 p.m. |
| August 16, 2026 | | Buffalo Bisons at Worcester Red Sox | 1:05 p.m. |
| August 18, 2026 | | Lehigh Valley IronPigs at Buffalo Bisons | 6:35 p.m. |
| August 19, 2026 | | Lehigh Valley IronPigs at Buffalo Bisons | 1:05 p.m. |
| August 20, 2026 | | Lehigh Valley IronPigs at Buffalo Bisons | 6:35 p.m. |
| August 21, 2026 | | Lehigh Valley IronPigs at Buffalo Bisons | 6:35 p.m. |
| August 22, 2026 | | Lehigh Valley IronPigs at Buffalo Bisons | 6:35 p.m. |
| August 23, 2026 | | Lehigh Valley IronPigs at Buffalo Bisons | 1:05 p.m. |
| August 25, 2026 | | Buffalo Bisons at Rochester Red Wings | 6:45 p.m. |
| August 26, 2026 | | Buffalo Bisons at Rochester Red Wings | 1:05 p.m. |
| August 27, 2026 | | Buffalo Bisons at Rochester Red Wings | 6:45 p.m. |
| August 28, 2026 | | Buffalo Bisons at Rochester Red Wings | 6:45 p.m. |
| August 29, 2026 | | Buffalo Bisons at Rochester Red Wings | 6:45 p.m. |
| August 30, 2026 | | Buffalo Bisons at Rochester Red Wings | 1:05 p.m. |
| September 1, 2026 | | Worcester Red Sox at Buffalo Bisons | 6:05 p.m. |
| September 2, 2026 | | Worcester Red Sox at Buffalo Bisons | 6:05 p.m. |
| September 3, 2026 | | Worcester Red Sox at Buffalo Bisons | 6:05 p.m. |
| September 4, 2026 | | Worcester Red Sox at Buffalo Bisons | 6:05 p.m. |
| September 5, 2026 | | Worcester Red Sox at Buffalo Bisons | 6:05 p.m. |
| September 6, 2026 | | Worcester Red Sox at Buffalo Bisons | 1:05 p.m. |
| September 8, 2026 | | Buffalo Bisons at Charlotte Knights | 6:35 p.m. |
| September 9, 2026 | | Buffalo Bisons at Charlotte Knights | 6:35 p.m. |
| September 10, 2026 | | Buffalo Bisons at Charlotte Knights | 7:04 p.m. |
| September 11, 2026 | | Buffalo Bisons at Charlotte Knights | 7:04 p.m. |
| September 12, 2026 | | Buffalo Bisons at Charlotte Knights | 5:35 p.m. |
| September 13, 2026 | | Buffalo Bisons at Charlotte Knights | |
| September 15, 2026 | | Rochester Red Wings at Buffalo Bisons | 6:05 p.m. |
| September 16, 2026 | | Rochester Red Wings at Buffalo Bisons | 6:05 p.m. |
| September 17, 2026 | | Rochester Red Wings at Buffalo Bisons | 6:05 p.m. |
| September 18, 2026 | | Rochester Red Wings at Buffalo Bisons | 6:05 p.m. |
| September 19, 2026 | | Rochester Red Wings at Buffalo Bisons | 1:05 p.m. |
| September 20, 2026 | | Rochester Red Wings at Buffalo Bisons | 12:05 p.m. |
Buffalo Bisons Schedule
