| | | |
| April 4, 2025 | W | Amarillo Sod Poodles 4 at San Antonio Missions 5 | Final |
| April 5, 2025 | W | Amarillo Sod Poodles 2 at San Antonio Missions 8 | Final |
| April 6, 2025 | L | Amarillo Sod Poodles 4 at San Antonio Missions 3 | Final |
| April 8, 2025 | W | San Antonio Missions 4 at Corpus Christi Hooks 3 | Final |
| April 9, 2025 | W | San Antonio Missions 8 at Corpus Christi Hooks 4 | Final |
| April 10, 2025 | W | San Antonio Missions 4 at Corpus Christi Hooks 3 | Final (10) |
| April 11, 2025 | L | San Antonio Missions 3 at Corpus Christi Hooks 4 | Final |
| April 12, 2025 | L | San Antonio Missions 0 at Corpus Christi Hooks 2 | Final |
| April 13, 2025 | W | San Antonio Missions 8 at Corpus Christi Hooks 2 | Final |
| April 15, 2025 | L | Northwest Arkansas Naturals 3 at San Antonio Missions 0 | Final |
| April 16, 2025 | W | Northwest Arkansas Naturals 1 at San Antonio Missions 4 | Final |
| April 17, 2025 | W | Northwest Arkansas Naturals 4 at San Antonio Missions 7 | Final |
| April 18, 2025 | W | Northwest Arkansas Naturals 3 at San Antonio Missions 4 | Final (10) |
| April 19, 2025 | L | Northwest Arkansas Naturals 6 at San Antonio Missions 0 | Final (12) |
| April 20, 2025 | L | Northwest Arkansas Naturals 12 at San Antonio Missions 7 | Final |
| April 22, 2025 | L | San Antonio Missions 4 at Amarillo Sod Poodles 15 | Final |
| April 23, 2025 | L | San Antonio Missions 2 at Amarillo Sod Poodles 4 | Final |
| April 24, 2025 | W | San Antonio Missions 13 at Amarillo Sod Poodles 11 | Final (10) |
| April 25, 2025 | | San Antonio Missions at Amarillo Sod Poodles | Ppd. |
| April 26, 2025 | L | San Antonio Missions 4 at Amarillo Sod Poodles 6 (Game 1) | Final (7) |
| April 26, 2025 | L | San Antonio Missions 3 at Amarillo Sod Poodles 5 (Game 2) | Final (7) |
| April 27, 2025 | W | San Antonio Missions 5 at Amarillo Sod Poodles 4 | Final |
| April 29, 2025 | W | Corpus Christi Hooks 0 at San Antonio Missions 2 | Final |
| April 30, 2025 | L | Corpus Christi Hooks 8 at San Antonio Missions 2 | Final |
| May 1, 2025 | L | Corpus Christi Hooks 3 at San Antonio Missions 1 | Final |
| May 2, 2025 | L | Corpus Christi Hooks 5 at San Antonio Missions 3 | Final |
| May 3, 2025 | W | Corpus Christi Hooks 1 at San Antonio Missions 4 | Final |
| May 4, 2025 | W | Corpus Christi Hooks 4 at San Antonio Missions 5 | Final |
| May 6, 2025 | W | Frisco RoughRiders 2 at San Antonio Missions 9 | Final |
| May 7, 2025 | L | Frisco RoughRiders 6 at San Antonio Missions 1 | Final |
| May 8, 2025 | L | Frisco RoughRiders 12 at San Antonio Missions 6 | Final |
| May 9, 2025 | L | Frisco RoughRiders 4 at San Antonio Missions 3 | Final |
| May 10, 2025 | W | Frisco RoughRiders 1 at San Antonio Missions 2 | Final |
| May 11, 2025 | W | Frisco RoughRiders 1 at San Antonio Missions 2 | Final |
| May 13, 2025 | L | San Antonio Missions 6 at Midland RockHounds 14 | Final |
| May 14, 2025 | L | San Antonio Missions 0 at Midland RockHounds 6 | Final |
| May 15, 2025 | L | San Antonio Missions 6 at Midland RockHounds 9 | Final |
| May 16, 2025 | W | San Antonio Missions 14 at Midland RockHounds 11 | Final |
| May 17, 2025 | W | San Antonio Missions 7 at Midland RockHounds 6 | Final |
| May 18, 2025 | L | San Antonio Missions 1 at Midland RockHounds 10 | Final |
| May 20, 2025 | W | Wichita Wind Surge 4 at San Antonio Missions 5 | Final |
| May 21, 2025 | L | Wichita Wind Surge 6 at San Antonio Missions 4 | Final |
| May 22, 2025 | W | Wichita Wind Surge 1 at San Antonio Missions 2 | Final |
| May 23, 2025 | W | Wichita Wind Surge 1 at San Antonio Missions 2 | Final |
| May 24, 2025 | W | Wichita Wind Surge 2 at San Antonio Missions 5 | Final |
| May 25, 2025 | W | Wichita Wind Surge 2 at San Antonio Missions 3 | Final |
| May 27, 2025 | | San Antonio Missions at Arkansas Travelers | Ppd. |
| May 28, 2025 | W | San Antonio Missions 4 at Arkansas Travelers 1 (Game 1) | Final (7) |
| May 28, 2025 | W | San Antonio Missions 1 at Arkansas Travelers 0 (Game 2) | Final (8) |
| May 29, 2025 | L | San Antonio Missions 4 at Arkansas Travelers 6 | Final |
| May 30, 2025 | W | San Antonio Missions 4 at Arkansas Travelers 2 | Final |
| May 31, 2025 | L | San Antonio Missions 2 at Arkansas Travelers 3 | Final (10) |
| June 1, 2025 | W | San Antonio Missions 4 at Arkansas Travelers 2 | Final (10) |
| June 3, 2025 | L | Midland RockHounds 1 at San Antonio Missions 0 | Final |
| June 4, 2025 | L | Midland RockHounds 10 at San Antonio Missions 7 | Final (10) |
| June 5, 2025 | W | Midland RockHounds 2 at San Antonio Missions 4 | Final |
| June 6, 2025 | W | Midland RockHounds 2 at San Antonio Missions 4 | Final |
| June 7, 2025 | W | Midland RockHounds 2 at San Antonio Missions 5 | Final |
| June 8, 2025 | L | Midland RockHounds 3 at San Antonio Missions 0 | Final |
| June 10, 2025 | L | San Antonio Missions 1 at Amarillo Sod Poodles 3 | Final |
| June 11, 2025 | W | San Antonio Missions 8 at Amarillo Sod Poodles 2 | Final |
| June 12, 2025 | W | San Antonio Missions 11 at Amarillo Sod Poodles 3 | Final |
| June 13, 2025 | W | San Antonio Missions 10 at Amarillo Sod Poodles 9 | Final |
| June 14, 2025 | L | San Antonio Missions 4 at Amarillo Sod Poodles 5 | Final |
| June 15, 2025 | W | San Antonio Missions 8 at Amarillo Sod Poodles 5 | Final |
| June 17, 2025 | W | Frisco RoughRiders 2 at San Antonio Missions 4 | Final |
| June 18, 2025 | W | Frisco RoughRiders 0 at San Antonio Missions 1 | Final |
| June 19, 2025 | L | Frisco RoughRiders 2 at San Antonio Missions 1 | Final |
| June 20, 2025 | W | Frisco RoughRiders 1 at San Antonio Missions 2 | Final |
| June 21, 2025 | W | Frisco RoughRiders 2 at San Antonio Missions 3 | Final |
| June 22, 2025 | L | Frisco RoughRiders 8 at San Antonio Missions 1 | Final |
| June 24, 2025 | W | San Antonio Missions 3 at Midland RockHounds 2 | Final |
| June 25, 2025 | L | San Antonio Missions 4 at Midland RockHounds 18 | Final |
| June 26, 2025 | | San Antonio Missions at Midland RockHounds | Susp. |
| June 27, 2025 | W | San Antonio Missions 6 at Midland RockHounds 2 (Game 1) | Final |
| June 27, 2025 | L | San Antonio Missions 4 at Midland RockHounds 5 (Game 2) | Final (8) |
| June 28, 2025 | W | San Antonio Missions 2 at Midland RockHounds 0 | Final |
| June 29, 2025 | L | San Antonio Missions 1 at Midland RockHounds 2 | Final |
| July 1, 2025 | W | Corpus Christi Hooks 6 at San Antonio Missions 7 | Final (10) |
| July 2, 2025 | L | Corpus Christi Hooks 9 at San Antonio Missions 3 | Final |
| July 3, 2025 | | Corpus Christi Hooks at San Antonio Missions | Susp. |
| July 4, 2025 | L | Corpus Christi Hooks 5 at San Antonio Missions 4 (Game 1) | Final |
| July 4, 2025 | L | San Antonio Missions 0 at Corpus Christi Hooks 7 (Game 2) | Final (7) |
| July 5, 2025 | L | San Antonio Missions 2 at Corpus Christi Hooks 8 | Final |
| July 6, 2025 | W | San Antonio Missions 5 at Corpus Christi Hooks 0 | Final |
| July 8, 2025 | L | San Antonio Missions 2 at Wichita Wind Surge 6 | Final |
| July 9, 2025 | W | San Antonio Missions 6 at Wichita Wind Surge 4 | Final |
| July 10, 2025 | W | San Antonio Missions 8 at Wichita Wind Surge 6 | Final |
| July 11, 2025 | W | San Antonio Missions 7 at Wichita Wind Surge 2 | Final |
| July 12, 2025 | W | San Antonio Missions 4 at Wichita Wind Surge 2 | Final |
| July 13, 2025 | W | San Antonio Missions 7 at Wichita Wind Surge 3 | Final |
| July 18, 2025 | L | Amarillo Sod Poodles 6 at San Antonio Missions 0 | Final |
| July 19, 2025 | L | Amarillo Sod Poodles 5 at San Antonio Missions 0 | Final |
| July 20, 2025 | W | Amarillo Sod Poodles 0 at San Antonio Missions 2 | Final |
| July 22, 2025 | L | Midland RockHounds 1 at San Antonio Missions 0 | Final |
| July 23, 2025 | L | Midland RockHounds 5 at San Antonio Missions 0 | Final |
| July 24, 2025 | L | Midland RockHounds 2 at San Antonio Missions 1 | Final |
| July 25, 2025 | L | Midland RockHounds 8 at San Antonio Missions 4 | Final |
| July 26, 2025 | L | Midland RockHounds 8 at San Antonio Missions 6 | Final (10) |
| July 27, 2025 | W | Midland RockHounds 1 at San Antonio Missions 6 | Final |
| July 29, 2025 | L | San Antonio Missions 2 at Frisco RoughRiders 4 | Final |
| July 30, 2025 | W | San Antonio Missions 7 at Frisco RoughRiders 4 | Final |
| July 31, 2025 | L | San Antonio Missions 3 at Frisco RoughRiders 12 | Final |
| August 1, 2025 | L | San Antonio Missions 1 at Frisco RoughRiders 3 | Final |
| August 2, 2025 | W | San Antonio Missions 4 at Frisco RoughRiders 2 | Final |
| August 3, 2025 | W | San Antonio Missions 4 at Frisco RoughRiders 0 | Final |
| August 5, 2025 | W | Springfield Cardinals 4 at San Antonio Missions 5 | Final |
| August 6, 2025 | L | Springfield Cardinals 8 at San Antonio Missions 5 | Final |
| August 7, 2025 | L | Springfield Cardinals 6 at San Antonio Missions 2 | Final |
| August 8, 2025 | L | Springfield Cardinals 2 at San Antonio Missions 0 | Final |
| August 9, 2025 | L | Springfield Cardinals 6 at San Antonio Missions 2 | Final |
| August 10, 2025 | L | Springfield Cardinals 5 at San Antonio Missions 3 | Final (10) |
| August 12, 2025 | | San Antonio Missions at Tulsa Drillers | 8:00 p.m. |
| August 13, 2025 | | San Antonio Missions at Tulsa Drillers | 8:00 p.m. |
| August 14, 2025 | | San Antonio Missions at Tulsa Drillers | 8:00 p.m. |
| August 15, 2025 | | San Antonio Missions at Tulsa Drillers | 8:00 p.m. |
| August 16, 2025 | | San Antonio Missions at Tulsa Drillers | 8:00 p.m. |
| August 17, 2025 | | San Antonio Missions at Tulsa Drillers | 1:00 p.m. |
| August 19, 2025 | | Amarillo Sod Poodles at San Antonio Missions | 8:05 p.m. |
| August 20, 2025 | | Amarillo Sod Poodles at San Antonio Missions | 8:05 p.m. |
| August 21, 2025 | | Amarillo Sod Poodles at San Antonio Missions | 8:05 p.m. |
| August 22, 2025 | | Amarillo Sod Poodles at San Antonio Missions | 8:05 p.m. |
| August 23, 2025 | | Amarillo Sod Poodles at San Antonio Missions | 8:05 p.m. |
| August 24, 2025 | | Amarillo Sod Poodles at San Antonio Missions | 8:05 p.m. |
| August 26, 2025 | | San Antonio Missions at Frisco RoughRiders | 8:05 p.m. |
| August 27, 2025 | | San Antonio Missions at Frisco RoughRiders | 8:05 p.m. |
| August 28, 2025 | | San Antonio Missions at Frisco RoughRiders | 8:05 p.m. |
| August 29, 2025 | | San Antonio Missions at Frisco RoughRiders | 8:05 p.m. |
| August 30, 2025 | | San Antonio Missions at Frisco RoughRiders | 8:05 p.m. |
| August 31, 2025 | | San Antonio Missions at Frisco RoughRiders | 7:05 p.m. |
| September 2, 2025 | | Corpus Christi Hooks at San Antonio Missions | 8:05 p.m. |
| September 3, 2025 | | Corpus Christi Hooks at San Antonio Missions | 8:05 p.m. |
| September 4, 2025 | | Corpus Christi Hooks at San Antonio Missions | 8:05 p.m. |
| September 5, 2025 | | Corpus Christi Hooks at San Antonio Missions | 8:05 p.m. |
| September 6, 2025 | | Corpus Christi Hooks at San Antonio Missions | 8:05 p.m. |
| September 7, 2025 | | Corpus Christi Hooks at San Antonio Missions | 7:05 p.m. |
| September 9, 2025 | | San Antonio Missions at Springfield Cardinals | 7:35 p.m. |
| September 10, 2025 | | San Antonio Missions at Springfield Cardinals | 7:35 p.m. |
| September 11, 2025 | | San Antonio Missions at Springfield Cardinals | 7:35 p.m. |
| September 12, 2025 | | San Antonio Missions at Springfield Cardinals | 8:05 p.m. |
| September 13, 2025 | | San Antonio Missions at Springfield Cardinals | 7:35 p.m. |
| September 14, 2025 | | San Antonio Missions at Springfield Cardinals | 2:05 p.m. |
San Antonio Missions Schedule
