| | | |
| April 4, 2025 | W | Portland Sea Dogs 14 at Reading Fightin Phils 6 | Final |
| April 5, 2025 | W | Portland Sea Dogs 7 at Reading Fightin Phils 4 | Final |
| April 6, 2025 | W | Portland Sea Dogs 3 at Reading Fightin Phils 2 | Final |
| April 8, 2025 | W | New Hampshire Fisher Cats 1 at Portland Sea Dogs 2 | Final (10) |
| April 9, 2025 | L | New Hampshire Fisher Cats 4 at Portland Sea Dogs 1 | Final |
| April 10, 2025 | W | New Hampshire Fisher Cats 3 at Portland Sea Dogs 14 | Final |
| April 11, 2025 | L | New Hampshire Fisher Cats 4 at Portland Sea Dogs 3 | Final (10) |
| April 12, 2025 | | New Hampshire Fisher Cats at Portland Sea Dogs | Ppd. |
| April 13, 2025 | | New Hampshire Fisher Cats at Portland Sea Dogs (Game 1) | Ppd. |
| April 13, 2025 | | New Hampshire Fisher Cats at Portland Sea Dogs (Game 2) | Ppd. |
| April 15, 2025 | W | Portland Sea Dogs 7 at Hartford Yard Goats 5 | Final |
| April 16, 2025 | W | Portland Sea Dogs 7 at Hartford Yard Goats 5 | Final (10) |
| April 17, 2025 | L | Portland Sea Dogs 3 at Hartford Yard Goats 6 | Final |
| April 18, 2025 | L | Portland Sea Dogs 4 at Hartford Yard Goats 11 | Final |
| April 19, 2025 | L | Portland Sea Dogs 2 at Hartford Yard Goats 4 | Final |
| April 20, 2025 | L | Portland Sea Dogs 1 at Hartford Yard Goats 3 | Final |
| April 22, 2025 | W | Reading Fightin Phils 8 at Portland Sea Dogs 9 | Final |
| April 23, 2025 | W | Reading Fightin Phils 1 at Portland Sea Dogs 5 | Final |
| April 24, 2025 | W | Reading Fightin Phils 3 at Portland Sea Dogs 4 | Final |
| April 25, 2025 | W | Reading Fightin Phils 1 at Portland Sea Dogs 2 | Final |
| April 26, 2025 | | Reading Fightin Phils at Portland Sea Dogs | Ppd. |
| April 27, 2025 | | Reading Fightin Phils at Portland Sea Dogs | Ppd. |
| April 29, 2025 | W | Portland Sea Dogs 9 at New Hampshire Fisher Cats 5 | Final |
| April 30, 2025 | L | Portland Sea Dogs 2 at New Hampshire Fisher Cats 3 (Game 1) | Final (7) |
| April 30, 2025 | W | New Hampshire Fisher Cats 2 at Portland Sea Dogs 3 (Game 2) | Final (7) |
| May 1, 2025 | W | Portland Sea Dogs 5 at New Hampshire Fisher Cats 3 | Final (10) |
| May 2, 2025 | L | Portland Sea Dogs 2 at New Hampshire Fisher Cats 8 | Final |
| May 3, 2025 | L | Portland Sea Dogs 0 at New Hampshire Fisher Cats 1 (Game 1) | Final (7) |
| May 3, 2025 | | New Hampshire Fisher Cats at Portland Sea Dogs (Game 2) | Ppd. |
| May 4, 2025 | W | Portland Sea Dogs 6 at New Hampshire Fisher Cats 5 (Game 1) | Final (7) |
| May 4, 2025 | W | New Hampshire Fisher Cats 1 at Portland Sea Dogs 5 (Game 2) | Final (7) |
| May 6, 2025 | | Chesapeake Baysox at Portland Sea Dogs | Ppd. |
| May 7, 2025 | L | Chesapeake Baysox 4 at Portland Sea Dogs 3 (Game 1) | Final (8) |
| May 7, 2025 | L | Chesapeake Baysox 2 at Portland Sea Dogs 1 (Game 2) | Final (7) |
| May 8, 2025 | L | Chesapeake Baysox 9 at Portland Sea Dogs 4 | Final (10) |
| May 9, 2025 | | Chesapeake Baysox at Portland Sea Dogs | Ppd. |
| May 10, 2025 | | Chesapeake Baysox at Portland Sea Dogs (Game 2) | Cancelled |
| May 10, 2025 | W | Chesapeake Baysox 3 at Portland Sea Dogs 4 (Game 1) | Final |
| May 11, 2025 | W | Chesapeake Baysox 5 at Portland Sea Dogs 6 | Final (10) |
| May 13, 2025 | | Portland Sea Dogs at Somerset Patriots | Ppd. |
| May 14, 2025 | | Portland Sea Dogs at Somerset Patriots | Ppd. |
| May 15, 2025 | W | Portland Sea Dogs 4 at Somerset Patriots 2 (Game 1) | Final (7) |
| May 15, 2025 | L | Portland Sea Dogs 0 at Somerset Patriots 3 (Game 2) | Final (7) |
| May 16, 2025 | L | Portland Sea Dogs 2 at Somerset Patriots 4 | Final (10) |
| May 17, 2025 | L | Portland Sea Dogs 5 at Somerset Patriots 11 | Final |
| May 18, 2025 | W | Portland Sea Dogs 4 at Somerset Patriots 1 | Final |
| May 20, 2025 | W | Reading Fightin Phils 3 at Portland Sea Dogs 4 | Final |
| May 21, 2025 | L | Reading Fightin Phils 5 at Portland Sea Dogs 1 (Game 1) | Final (7) |
| May 21, 2025 | L | Reading Fightin Phils 3 at Portland Sea Dogs 1 (Game 2) | Final (7) |
| May 22, 2025 | W | Reading Fightin Phils 3 at Portland Sea Dogs 6 | Final |
| May 23, 2025 | | Reading Fightin Phils at Portland Sea Dogs (Game 2) | Cancelled |
| May 23, 2025 | W | Reading Fightin Phils 0 at Portland Sea Dogs 6 (Game 1) | Final |
| May 24, 2025 | W | Reading Fightin Phils 1 at Portland Sea Dogs 4 | Final |
| May 25, 2025 | L | Reading Fightin Phils 5 at Portland Sea Dogs 3 | Final |
| May 27, 2025 | L | Portland Sea Dogs 2 at Altoona Curve 4 | Final |
| May 28, 2025 | | Portland Sea Dogs at Altoona Curve | Ppd. |
| May 29, 2025 | W | Portland Sea Dogs 3 at Altoona Curve 0 (Game 1) | Final (7) |
| May 29, 2025 | W | Portland Sea Dogs 9 at Altoona Curve 6 (Game 2) | Final (7) |
| May 30, 2025 | | Portland Sea Dogs at Altoona Curve | Susp. |
| May 31, 2025 | W | Portland Sea Dogs 9 at Altoona Curve 3 (Game 1) | Final |
| May 31, 2025 | L | Portland Sea Dogs 7 at Altoona Curve 9 (Game 2) | Final (8) |
| June 1, 2025 | L | Portland Sea Dogs 5 at Altoona Curve 7 | Final |
| June 3, 2025 | W | Hartford Yard Goats 3 at Portland Sea Dogs 6 | Final |
| June 4, 2025 | L | Hartford Yard Goats 4 at Portland Sea Dogs 2 | Final |
| June 5, 2025 | L | Hartford Yard Goats 8 at Portland Sea Dogs 6 | Final (11) |
| June 6, 2025 | | Hartford Yard Goats at Portland Sea Dogs | Susp. |
| June 7, 2025 | L | Hartford Yard Goats 9 at Portland Sea Dogs 2 (Game 1) | Final |
| June 7, 2025 | L | Hartford Yard Goats 4 at Portland Sea Dogs 0 (Game 2) | Final (7) |
| June 8, 2025 | L | Hartford Yard Goats 6 at Portland Sea Dogs 2 | Final |
| June 10, 2025 | L | Portland Sea Dogs 1 at Somerset Patriots 8 | Final |
| June 11, 2025 | W | Portland Sea Dogs 4 at Somerset Patriots 3 (Game 1) | Final (7) |
| June 11, 2025 | L | Portland Sea Dogs 2 at Somerset Patriots 9 (Game 2) | Final (7) |
| June 12, 2025 | W | Portland Sea Dogs 6 at Somerset Patriots 1 | Final |
| June 13, 2025 | L | Portland Sea Dogs 1 at Somerset Patriots 4 | Final |
| June 14, 2025 | W | Portland Sea Dogs 7 at Somerset Patriots 2 | Final |
| June 15, 2025 | L | Portland Sea Dogs 1 at Somerset Patriots 3 | Final |
| June 17, 2025 | L | Akron RubberDucks 1 at Portland Sea Dogs 0 | Final |
| June 18, 2025 | L | Akron RubberDucks 6 at Portland Sea Dogs 3 | Final |
| June 19, 2025 | L | Akron RubberDucks 7 at Portland Sea Dogs 6 | Final |
| June 20, 2025 | W | Akron RubberDucks 2 at Portland Sea Dogs 8 | Final |
| June 21, 2025 | W | Akron RubberDucks 4 at Portland Sea Dogs 5 | Final |
| June 22, 2025 | W | Akron RubberDucks 0 at Portland Sea Dogs 10 | Final |
| June 24, 2025 | W | Portland Sea Dogs 4 at Binghamton Rumble Ponies 3 | Final |
| June 25, 2025 | L | Portland Sea Dogs 1 at Binghamton Rumble Ponies 5 | Final |
| June 26, 2025 | L | Portland Sea Dogs 1 at Binghamton Rumble Ponies 2 | Final |
| June 27, 2025 | L | Portland Sea Dogs 1 at Binghamton Rumble Ponies 3 | Final |
| June 28, 2025 | L | Portland Sea Dogs 2 at Binghamton Rumble Ponies 3 | Final (11) |
| June 29, 2025 | W | Portland Sea Dogs 3 at Binghamton Rumble Ponies 1 | Final |
| July 1, 2025 | W | Portland Sea Dogs 11 at New Hampshire Fisher Cats 6 | Final (11) |
| July 2, 2025 | L | Portland Sea Dogs 1 at New Hampshire Fisher Cats 4 | Final |
| July 3, 2025 | L | Portland Sea Dogs 5 at New Hampshire Fisher Cats 7 | Final |
| July 4, 2025 | W | New Hampshire Fisher Cats 1 at Portland Sea Dogs 7 | Final |
| July 5, 2025 | L | New Hampshire Fisher Cats 4 at Portland Sea Dogs 2 | Final |
| July 6, 2025 | L | New Hampshire Fisher Cats 10 at Portland Sea Dogs 5 | Final |
| July 8, 2025 | L | Hartford Yard Goats 6 at Portland Sea Dogs 1 | Final |
| July 9, 2025 | L | Hartford Yard Goats 3 at Portland Sea Dogs 2 | Final |
| July 10, 2025 | L | Hartford Yard Goats 3 at Portland Sea Dogs 1 | Final (10) |
| July 11, 2025 | W | Hartford Yard Goats 3 at Portland Sea Dogs 4 | Final |
| July 12, 2025 | W | Hartford Yard Goats 1 at Portland Sea Dogs 7 | Final |
| July 13, 2025 | W | Hartford Yard Goats 1 at Portland Sea Dogs 5 | Final |
| July 18, 2025 | L | Portland Sea Dogs 3 at Reading Fightin Phils 6 | Final |
| July 19, 2025 | L | Portland Sea Dogs 0 at Reading Fightin Phils 3 | Final |
| July 20, 2025 | W | Portland Sea Dogs 4 at Reading Fightin Phils 3 | Final (12) |
| July 22, 2025 | W | Portland Sea Dogs 3 at Richmond Flying Squirrels 2 | Final (11) |
| July 23, 2025 | W | Portland Sea Dogs 6 at Richmond Flying Squirrels 5 | Final (10) |
| July 24, 2025 | W | Portland Sea Dogs 5 at Richmond Flying Squirrels 3 | Final |
| July 25, 2025 | L | Portland Sea Dogs 2 at Richmond Flying Squirrels 3 | Final |
| July 26, 2025 | W | Portland Sea Dogs 5 at Richmond Flying Squirrels 1 | Final |
| July 27, 2025 | | Portland Sea Dogs at Richmond Flying Squirrels | Cancelled |
| July 29, 2025 | W | Altoona Curve 3 at Portland Sea Dogs 4 | Final |
| July 30, 2025 | L | Altoona Curve 6 at Portland Sea Dogs 2 | Final |
| July 31, 2025 | W | Altoona Curve 1 at Portland Sea Dogs 2 | Final |
| August 1, 2025 | L | Altoona Curve 2 at Portland Sea Dogs 1 | Final |
| August 2, 2025 | W | Altoona Curve 1 at Portland Sea Dogs 4 | Final |
| August 3, 2025 | L | Altoona Curve 11 at Portland Sea Dogs 4 | Final |
| August 5, 2025 | W | Portland Sea Dogs 1 at Harrisburg Senators 0 | Final |
| August 6, 2025 | L | Portland Sea Dogs 3 at Harrisburg Senators 6 | Final |
| August 7, 2025 | L | Portland Sea Dogs 4 at Harrisburg Senators 5 | Final |
| August 8, 2025 | L | Portland Sea Dogs 1 at Harrisburg Senators 9 | Final |
| August 9, 2025 | W | Portland Sea Dogs 4 at Harrisburg Senators 3 | Final (11) |
| August 10, 2025 | L | Portland Sea Dogs 1 at Harrisburg Senators 3 | Final |
| August 12, 2025 | W | Somerset Patriots 3 at Portland Sea Dogs 6 | Final |
| August 13, 2025 | L | Somerset Patriots 6 at Portland Sea Dogs 3 | Final |
| August 14, 2025 | W | Somerset Patriots 2 at Portland Sea Dogs 3 | Final |
| August 15, 2025 | W | Somerset Patriots 2 at Portland Sea Dogs 3 | Final |
| August 16, 2025 | L | Somerset Patriots 8 at Portland Sea Dogs 5 | Final |
| August 17, 2025 | L | Somerset Patriots 4 at Portland Sea Dogs 3 | Final (10) |
| August 19, 2025 | W | Binghamton Rumble Ponies 3 at Portland Sea Dogs 8 | Final |
| August 20, 2025 | L | Binghamton Rumble Ponies 4 at Portland Sea Dogs 1 | Final |
| August 21, 2025 | W | Binghamton Rumble Ponies 0 at Portland Sea Dogs 2 | Final |
| August 22, 2025 | L | Binghamton Rumble Ponies 5 at Portland Sea Dogs 2 | Final |
| August 23, 2025 | W | Binghamton Rumble Ponies 2 at Portland Sea Dogs 8 | Final |
| August 24, 2025 | L | Binghamton Rumble Ponies 12 at Portland Sea Dogs 10 | Final |
| August 26, 2025 | W | Portland Sea Dogs 6 at Hartford Yard Goats 2 | Final |
| August 27, 2025 | L | Portland Sea Dogs 8 at Hartford Yard Goats 9 | Final (11) |
| August 28, 2025 | W | Portland Sea Dogs 15 at Hartford Yard Goats 3 | Final |
| August 29, 2025 | W | Portland Sea Dogs 6 at Hartford Yard Goats 2 | Final |
| August 30, 2025 | W | Portland Sea Dogs 4 at Hartford Yard Goats 3 | Final (10) |
| August 31, 2025 | L | Portland Sea Dogs 3 at Hartford Yard Goats 7 | Final |
| September 2, 2025 | W | Erie SeaWolves 1 at Portland Sea Dogs 8 | Final |
| September 3, 2025 | L | Erie SeaWolves 10 at Portland Sea Dogs 4 | Final |
| September 4, 2025 | W | Erie SeaWolves 2 at Portland Sea Dogs 13 | Final |
| September 5, 2025 | L | Erie SeaWolves 10 at Portland Sea Dogs 1 | Final |
| September 6, 2025 | L | Erie SeaWolves 8 at Portland Sea Dogs 3 | Final |
| September 7, 2025 | L | Erie SeaWolves 5 at Portland Sea Dogs 0 | Final |
| September 9, 2025 | L | Portland Sea Dogs 0 at Binghamton Rumble Ponies 1 | Final |
| September 10, 2025 | L | Portland Sea Dogs 5 at Binghamton Rumble Ponies 6 | Final (11) |
| September 11, 2025 | W | Portland Sea Dogs 8 at Binghamton Rumble Ponies 7 | Final |
| September 12, 2025 | L | Portland Sea Dogs 4 at Binghamton Rumble Ponies 5 | Final |
| September 13, 2025 | L | Portland Sea Dogs 0 at Binghamton Rumble Ponies 1 | Final |
| September 14, 2025 | L | Portland Sea Dogs 0 at Binghamton Rumble Ponies 1 | Final |
Portland Sea Dogs Schedule
