| | | |
| March 7, 2026 | | Phoenix Rising FC at San Antonio FC | 8:30 p.m. |
| March 14, 2026 | | San Antonio FC at FC Tulsa | 7:00 p.m. |
| March 21, 2026 | | New Mexico United at San Antonio FC | 7:30 p.m. |
| March 29, 2026 | | Lexington SC at San Antonio FC | 3:00 p.m. |
| April 4, 2026 | | San Antonio FC at Monterey Bay FC | 9:00 p.m. |
| April 8, 2026 | | San Antonio FC at Orange County SC | 9:00 p.m. |
| April 11, 2026 | | Miami FC at San Antonio FC | 7:30 p.m. |
| April 18, 2026 | | San Antonio FC at El Paso Locomotive FC | 8:00 p.m. |
| April 25, 2026 | | Birmingham Legion FC at San Antonio FC | 7:30 p.m. |
| May 2, 2026 | | Colorado Springs Switchbacks FC at San Antonio FC | 7:30 p.m. |
| May 9, 2026 | | San Antonio FC at Phoenix Rising FC | 9:00 p.m. |
| May 16, 2026 | | San Antonio FC at One Knoxville SC (USL Cup) | 6:00 p.m. |
| May 23, 2026 | | Sacramento Republic FC at San Antonio FC | 7:30 p.m. |
| May 27, 2026 | | San Antonio FC at Sporting Club Jacksonville | 6:30 p.m. |
| June 6, 2026 | | San Antonio FC at FC Tulsa | 7:30 p.m. |
| June 13, 2026 | | San Antonio FC at Lexington SC | 6:00 p.m. |
| June 24, 2026 | | San Antonio FC at Colorado Springs Switchbacks FC | 8:00 p.m. |
| July 4, 2026 | | Monterey Bay FC at San Antonio FC | 8:00 p.m. |
| July 11, 2026 | | Chattanooga Red Wolves SC at San Antonio FC (USL Cup) | 8:00 p.m. |
| July 18, 2026 | | Las Vegas Lights FC at San Antonio FC | 8:00 p.m. |
| July 25, 2026 | | San Antonio FC at Brooklyn FC | 6:00 p.m. |
| August 1, 2026 | | Indy Eleven at San Antonio FC | 8:00 p.m. |
| August 8, 2026 | | San Antonio FC at Louisville City FC | 7:00 p.m. |
| August 15, 2026 | | El Paso Locomotive FC at San Antonio FC | 8:00 p.m. |
| August 22, 2026 | | Oakland Roots SC at San Antonio FC | 8:00 p.m. |
| August 30, 2026 | | San Antonio FC at New Mexico United | 8:00 p.m. |
| September 5, 2026 | | FC Tulsa at San Antonio FC | 7:30 p.m. |
| September 11, 2026 | | San Antonio FC at Colorado Springs Switchbacks FC | 9:00 p.m. |
| September 20, 2026 | | San Antonio FC at Sacramento Republic FC | 6:00 p.m. |
| September 26, 2026 | | Tampa Bay Rowdies at San Antonio FC | 7:30 p.m. |
| October 3, 2026 | | San Antonio FC at Las Vegas Lights FC | 9:30 p.m. |
| October 10, 2026 | | San Antonio FC at Oakland Roots SC | 9:00 p.m. |
| October 17, 2026 | | New Mexico United at San Antonio FC | 7:30 p.m. |
| October 24, 2026 | | Orange County SC at San Antonio FC | 8:30 p.m. |
San Antonio FC Schedule
