| | | |
| March 31, 2025 | L | Vegas Knight Hawks 48 at San Diego Strike Force 41 | Final |
| April 6, 2025 | L | San Diego Strike Force 18 at Bay Area Panthers 41 | Final |
| April 11, 2025 | W | San Diego Strike Force 35 at Vegas Knight Hawks 27 | Final |
| April 27, 2025 | W | Tucson Sugar Skulls 22 at San Diego Strike Force 45 | Final |
| May 4, 2025 | | San Diego Strike Force at Bay Area Panthers | 8:05 p.m. |
| May 11, 2025 | | Northern Arizona Wranglers at San Diego Strike Force | 9:05 p.m. |
| May 17, 2025 | | San Diego Strike Force at San Antonio Gunslingers | 7:05 p.m. |
| May 25, 2025 | | Vegas Knight Hawks at San Diego Strike Force | 9:05 p.m. |
| May 30, 2025 | | Northern Arizona Wranglers at San Diego Strike Force | 9:05 p.m. |
| June 7, 2025 | | San Diego Strike Force at Tucson Sugar Skulls | 9:05 p.m. |
| June 14, 2025 | | San Diego Strike Force at Northern Arizona Wranglers | 9:05 p.m. |
| June 22, 2025 | | San Antonio Gunslingers at San Diego Strike Force | 9:05 p.m. |
| July 7, 2025 | | Bay Area Panthers at San Diego Strike Force | 10:05 p.m. |
| July 12, 2025 | | San Diego Strike Force at Arizona Rattlers | 9:05 p.m. |
| July 19, 2025 | | San Diego Strike Force at Fishers Freight | 7:05 p.m. |
| July 27, 2025 | | Arizona Rattlers at San Diego Strike Force | 9:05 p.m. |
San Diego Strike Force Schedule
