Houston Gamblers Schedule
All times Eastern
Complete Schedule
| March 28, 2025 | L | St. Louis Battlehawks 31 at Houston Gamblers 6 | Final |
| April 6, 2025 | L | Houston Gamblers 9 at Dallas Renegades 11 | Final |
| April 12, 2025 | W | Houston Gamblers 18 at Memphis Showboats 17 | Final |
| April 19, 2025 | L | Birmingham Stallions 23 at Houston Gamblers 16 | Final |
| April 27, 2025 | W | Houston Gamblers 27 at San Antonio Brahmas 3 | Final |
| May 3, 2025 | W | Memphis Showboats 20 at Houston Gamblers 21 | Final |
| May 11, 2025 | L | Houston Gamblers 25 at Birmingham Stallions 33 | Final |
| May 17, 2025 | L | Michigan Panthers 30 at Houston Gamblers 18 | Final |
| May 25, 2025 | W | DC Defenders 21 at Houston Gamblers 24 | Final |
| May 31, 2025 | W | Houston Gamblers 19 at Michigan Panthers 12 | Final |
