| | | |
| April 6, 2025 | L | York United FC 2 at Vancouver FC 0 | Final |
| April 13, 2025 | L | Atletico Ottawa 4 at Vancouver FC 1 | Final |
| April 18, 2025 | T | Vancouver FC 1 at Cavalry FC 1 | Final |
| April 26, 2025 | T | Pacific FC 1 at Vancouver FC 1 | Final |
| May 3, 2025 | | Vancouver FC at Valour FC | 7:00 p.m. |
| May 17, 2025 | | HFX Wanderers FC at Vancouver FC | 8:00 p.m. |
| May 25, 2025 | | Vancouver FC at York United FC | 2:00 p.m. |
| May 30, 2025 | | Atletico Ottawa at Vancouver FC | 10:00 p.m. |
| June 4, 2025 | | Vancouver FC at Valour FC | 12:00 p.m. |
| June 15, 2025 | | Forge FC at Vancouver FC | 4:00 p.m. |
| June 21, 2025 | | Vancouver FC at HFX Wanderers FC | 3:00 p.m. |
| June 27, 2025 | | Vancouver FC at Pacific FC | 10:00 p.m. |
| July 5, 2025 | | Vancouver FC at Forge FC | 7:00 p.m. |
| July 13, 2025 | | Cavalry FC at Vancouver FC | 9:00 p.m. |
| July 19, 2025 | | Vancouver FC at York United FC | 4:00 p.m. |
| July 25, 2025 | | Valour FC at Vancouver FC | 10:00 p.m. |
| August 4, 2025 | | Vancouver FC at HFX Wanderers FC | 3:00 p.m. |
| August 10, 2025 | | Pacific FC at Vancouver FC | 6:00 p.m. |
| August 17, 2025 | | Vancouver FC at Cavalry FC | 6:00 p.m. |
| August 22, 2025 | | Forge FC at Vancouver FC | 10:00 p.m. |
| August 30, 2025 | | Vancouver FC at Atletico Ottawa | 7:00 p.m. |
| September 5, 2025 | | Valour FC at Vancouver FC | 10:30 p.m. |
| September 13, 2025 | | Vancouver FC at Pacific FC | 7:00 p.m. |
| September 21, 2025 | | York United FC at Vancouver FC | 6:00 p.m. |
| September 28, 2025 | | HFX Wanderers FC at Vancouver FC | 6:00 p.m. |
| October 4, 2025 | | Vancouver FC at Forge FC | 5:00 p.m. |
| October 12, 2025 | | Vancouver FC at Atletico Ottawa | 3:00 p.m. |
| October 18, 2025 | | Cavalry FC at Vancouver FC | 4:00 p.m. |
Vancouver FC Schedule
