Columbus Destroyers Schedule
All times Eastern
Complete Schedule
| April 27, 2019 | L | Columbus Destroyers 19 at Albany Empire 35 | Final |
| May 4, 2019 | L | Columbus Destroyers 35 at Atlantic City Blackjacks 42 | Final |
| May 10, 2019 | L | Columbus Destroyers 30 at Baltimore Brigade 48 | Final |
| May 18, 2019 | L | Albany Empire 56 at Columbus Destroyers 40 | Final |
| May 25, 2019 | L | Washington Valor 29 at Columbus Destroyers 27 | Final |
| June 1, 2019 | L | Columbus Destroyers 35 at Philadelphia Soul 47 | Final |
| June 7, 2019 | W | Atlantic City Blackjacks 50 at Columbus Destroyers 54 | Final |
| June 15, 2019 | L | Baltimore Brigade 44 at Columbus Destroyers 39 | Final |
| June 22, 2019 | L | Philadelphia Soul 42 at Columbus Destroyers 35 | Final |
| June 28, 2019 | L | Columbus Destroyers 12 at Baltimore Brigade 50 | Final |
| July 14, 2019 | L | Albany Empire 49 at Columbus Destroyers 18 | Final |
| July 20, 2019 | L | Columbus Destroyers 50 at Washington Valor 56 | Final |
