| | | |
| March 28, 2025 | W | Gwinnett Stripers 1 at Charlotte Knights 9 | Final |
| March 29, 2025 | W | Gwinnett Stripers 4 at Charlotte Knights 12 | Final |
| March 30, 2025 | W | Gwinnett Stripers 6 at Charlotte Knights 9 | Final |
| April 1, 2025 | W | Norfolk Tides 3 at Charlotte Knights 4 | Final |
| April 2, 2025 | L | Norfolk Tides 3 at Charlotte Knights 1 | Final |
| April 3, 2025 | L | Norfolk Tides 6 at Charlotte Knights 3 | Final |
| April 4, 2025 | W | Norfolk Tides 6 at Charlotte Knights 7 | Final |
| April 5, 2025 | L | Norfolk Tides 3 at Charlotte Knights 2 | Final |
| April 6, 2025 | W | Norfolk Tides 8 at Charlotte Knights 9 | Final |
| April 8, 2025 | L | Charlotte Knights 0 at Jacksonville Jumbo Shrimp 3 | Final |
| April 9, 2025 | L | Charlotte Knights 1 at Jacksonville Jumbo Shrimp 2 | Final |
| April 10, 2025 | L | Charlotte Knights 5 at Jacksonville Jumbo Shrimp 8 | Final |
| April 11, 2025 | | Charlotte Knights at Jacksonville Jumbo Shrimp | Ppd. |
| April 12, 2025 | L | Charlotte Knights 3 at Jacksonville Jumbo Shrimp 4 (Game 1) | Final (7) |
| April 12, 2025 | L | Charlotte Knights 1 at Jacksonville Jumbo Shrimp 3 (Game 2) | Final (7) |
| April 13, 2025 | L | Charlotte Knights 3 at Jacksonville Jumbo Shrimp 4 | Final |
| April 15, 2025 | L | Nashville Sounds 6 at Charlotte Knights 3 | Final |
| April 16, 2025 | L | Nashville Sounds 11 at Charlotte Knights 7 | Final (10) |
| April 17, 2025 | L | Nashville Sounds 5 at Charlotte Knights 4 | Final |
| April 18, 2025 | W | Nashville Sounds 1 at Charlotte Knights 2 | Final |
| April 19, 2025 | L | Nashville Sounds 10 at Charlotte Knights 4 | Final |
| April 20, 2025 | L | Nashville Sounds 14 at Charlotte Knights 11 | Final |
| April 22, 2025 | W | Charlotte Knights 5 at Scranton/Wilkes-Barre RailRiders 4 | Final (11) |
| April 23, 2025 | L | Charlotte Knights 0 at Scranton/Wilkes-Barre RailRiders 5 | Final |
| April 24, 2025 | W | Charlotte Knights 10 at Scranton/Wilkes-Barre RailRiders 3 | Final |
| April 25, 2025 | W | Charlotte Knights 4 at Scranton/Wilkes-Barre RailRiders 1 | Final (7) |
| April 26, 2025 | W | Charlotte Knights 8 at Scranton/Wilkes-Barre RailRiders 7 | Final |
| April 27, 2025 | W | Charlotte Knights 13 at Scranton/Wilkes-Barre RailRiders 12 | Final (12) |
| April 29, 2025 | W | Norfolk Tides 1 at Charlotte Knights 6 | Final |
| April 30, 2025 | W | Norfolk Tides 8 at Charlotte Knights 9 | Final |
| May 1, 2025 | W | Norfolk Tides 4 at Charlotte Knights 7 | Final |
| May 2, 2025 | L | Norfolk Tides 11 at Charlotte Knights 3 | Final |
| May 3, 2025 | L | Norfolk Tides 11 at Charlotte Knights 1 | Final |
| May 4, 2025 | L | Norfolk Tides 9 at Charlotte Knights 3 | Final |
| May 6, 2025 | W | Memphis Redbirds 3 at Charlotte Knights 5 | Final (11) |
| May 7, 2025 | W | Memphis Redbirds 11 at Charlotte Knights 12 | Final (10) |
| May 8, 2025 | | Memphis Redbirds at Charlotte Knights | Ppd. |
| May 9, 2025 | L | Memphis Redbirds 13 at Charlotte Knights 10 | Final |
| May 10, 2025 | L | Memphis Redbirds 8 at Charlotte Knights 4 (Game 1) | Final (7) |
| May 10, 2025 | W | Memphis Redbirds 2 at Charlotte Knights 3 (Game 2) | Final (7) |
| May 11, 2025 | W | Memphis Redbirds 5 at Charlotte Knights 6 | Final |
| May 13, 2025 | W | Charlotte Knights 8 at Gwinnett Stripers 5 | Final |
| May 14, 2025 | L | Charlotte Knights 4 at Gwinnett Stripers 7 | Final |
| May 15, 2025 | W | Charlotte Knights 7 at Gwinnett Stripers 1 | Final |
| May 16, 2025 | L | Charlotte Knights 6 at Gwinnett Stripers 7 | Final |
| May 17, 2025 | W | Charlotte Knights 5 at Gwinnett Stripers 3 | Final |
| May 18, 2025 | L | Charlotte Knights 0 at Gwinnett Stripers 6 | Final |
| May 20, 2025 | L | Round Rock Express 5 at Charlotte Knights 1 | Final |
| May 21, 2025 | W | Round Rock Express 3 at Charlotte Knights 7 | Final |
| May 22, 2025 | W | Round Rock Express 0 at Charlotte Knights 8 | Final |
| May 23, 2025 | L | Round Rock Express 22 at Charlotte Knights 13 | Final |
| May 24, 2025 | L | Round Rock Express 8 at Charlotte Knights 6 | Final |
| May 25, 2025 | W | Round Rock Express 4 at Charlotte Knights 7 | Final |
| May 27, 2025 | L | Charlotte Knights 9 at Buffalo Bisons 10 | Final |
| May 28, 2025 | | Charlotte Knights at Buffalo Bisons | Ppd. |
| May 29, 2025 | L | Charlotte Knights 2 at Buffalo Bisons 3 (Game 1) | Final (7) |
| May 29, 2025 | L | Charlotte Knights 2 at Buffalo Bisons 5 (Game 2) | Final (7) |
| May 30, 2025 | W | Charlotte Knights 5 at Buffalo Bisons 3 | Final |
| May 31, 2025 | L | Charlotte Knights 4 at Buffalo Bisons 5 | Final |
| June 1, 2025 | W | Charlotte Knights 8 at Buffalo Bisons 4 | Final |
| June 3, 2025 | L | Lehigh Valley IronPigs 10 at Charlotte Knights 6 | Final |
| June 4, 2025 | W | Lehigh Valley IronPigs 3 at Charlotte Knights 8 | Final |
| June 5, 2025 | L | Lehigh Valley IronPigs 11 at Charlotte Knights 4 | Final |
| June 6, 2025 | W | Lehigh Valley IronPigs 2 at Charlotte Knights 14 | Final |
| June 7, 2025 | W | Lehigh Valley IronPigs 4 at Charlotte Knights 7 | Final |
| June 8, 2025 | W | Lehigh Valley IronPigs 9 at Charlotte Knights 10 | Final |
| June 10, 2025 | W | Charlotte Knights 7 at Durham Bulls 6 | Final |
| June 11, 2025 | L | Charlotte Knights 1 at Durham Bulls 5 | Final |
| June 12, 2025 | L | Charlotte Knights 1 at Durham Bulls 2 | Final |
| June 13, 2025 | L | Charlotte Knights 5 at Durham Bulls 6 | Final |
| June 14, 2025 | L | Charlotte Knights 1 at Durham Bulls 3 | Final |
| June 15, 2025 | W | Charlotte Knights 6 at Durham Bulls 3 | Final |
| June 17, 2025 | W | Gwinnett Stripers 3 at Charlotte Knights 6 | Final |
| June 18, 2025 | W | Gwinnett Stripers 3 at Charlotte Knights 9 | Final |
| June 19, 2025 | L | Gwinnett Stripers 8 at Charlotte Knights 1 | Final |
| June 20, 2025 | L | Gwinnett Stripers 7 at Charlotte Knights 3 | Final |
| June 21, 2025 | W | Gwinnett Stripers 1 at Charlotte Knights 4 | Final |
| June 22, 2025 | L | Gwinnett Stripers 5 at Charlotte Knights 4 | Final |
| June 24, 2025 | L | Charlotte Knights 3 at Toledo Mud Hens 4 | Final |
| June 25, 2025 | W | Charlotte Knights 4 at Toledo Mud Hens 3 | Final (10) |
| June 26, 2025 | W | Charlotte Knights 12 at Toledo Mud Hens 9 | Final |
| June 27, 2025 | W | Charlotte Knights 7 at Toledo Mud Hens 5 | Final |
| June 28, 2025 | W | Charlotte Knights 9 at Toledo Mud Hens 0 | Final |
| June 29, 2025 | L | Charlotte Knights 3 at Toledo Mud Hens 5 | Final |
| July 1, 2025 | L | Jacksonville Jumbo Shrimp 5 at Charlotte Knights 0 | Final |
| July 2, 2025 | W | Jacksonville Jumbo Shrimp 3 at Charlotte Knights 4 | Final |
| July 3, 2025 | W | Jacksonville Jumbo Shrimp 5 at Charlotte Knights 10 | Final |
| July 4, 2025 | L | Charlotte Knights 0 at Jacksonville Jumbo Shrimp 4 | Final |
| July 5, 2025 | W | Charlotte Knights 7 at Jacksonville Jumbo Shrimp 2 | Final |
| July 6, 2025 | | Charlotte Knights at Jacksonville Jumbo Shrimp | Ppd. |
| July 8, 2025 | | Charlotte Knights at Memphis Redbirds | Ppd. |
| July 9, 2025 | W | Charlotte Knights 10 at Memphis Redbirds 4 (Game 1) | Final (7) |
| July 9, 2025 | W | Charlotte Knights 9 at Memphis Redbirds 4 (Game 2) | Final (7) |
| July 10, 2025 | L | Charlotte Knights 1 at Memphis Redbirds 8 | Final |
| July 11, 2025 | L | Charlotte Knights 1 at Memphis Redbirds 4 | Final |
| July 12, 2025 | W | Charlotte Knights 10 at Memphis Redbirds 9 | Final |
| July 13, 2025 | W | Charlotte Knights 4 at Memphis Redbirds 2 | Final |
| July 18, 2025 | L | Durham Bulls 7 at Charlotte Knights 5 | Final |
| July 19, 2025 | L | Durham Bulls 7 at Charlotte Knights 4 | Final |
| July 20, 2025 | L | Durham Bulls 10 at Charlotte Knights 7 | Final (10) |
| July 22, 2025 | L | Charlotte Knights 7 at Nashville Sounds 10 | Final |
| July 23, 2025 | L | Charlotte Knights 13 at Nashville Sounds 14 | Final (11) |
| July 24, 2025 | W | Charlotte Knights 2 at Nashville Sounds 0 | Final |
| July 25, 2025 | W | Charlotte Knights 3 at Nashville Sounds 0 | Final |
| July 26, 2025 | L | Charlotte Knights 4 at Nashville Sounds 5 | Final |
| July 27, 2025 | L | Charlotte Knights 2 at Nashville Sounds 3 | Final (10) |
| July 29, 2025 | L | Rochester Red Wings 16 at Charlotte Knights 1 | Final |
| July 30, 2025 | L | Rochester Red Wings 13 at Charlotte Knights 8 | Final |
| July 31, 2025 | W | Rochester Red Wings 5 at Charlotte Knights 7 | Final |
| August 1, 2025 | W | Rochester Red Wings 3 at Charlotte Knights 4 | Final |
| August 2, 2025 | L | Rochester Red Wings 9 at Charlotte Knights 8 | Final |
| August 3, 2025 | L | Rochester Red Wings 12 at Charlotte Knights 7 | Final |
| August 5, 2025 | L | Charlotte Knights 0 at Syracuse Mets 11 | Final |
| August 6, 2025 | W | Charlotte Knights 6 at Syracuse Mets 0 | Final (5) |
| August 7, 2025 | L | Charlotte Knights 3 at Syracuse Mets 10 | Final |
| August 8, 2025 | L | Charlotte Knights 5 at Syracuse Mets 9 | Final |
| August 9, 2025 | W | Charlotte Knights 12 at Syracuse Mets 6 | Final |
| August 10, 2025 | W | Charlotte Knights 5 at Syracuse Mets 1 | Final |
| August 12, 2025 | W | Memphis Redbirds 6 at Charlotte Knights 13 | Final |
| August 13, 2025 | L | Memphis Redbirds 14 at Charlotte Knights 5 | Final |
| August 14, 2025 | | Memphis Redbirds at Charlotte Knights | 7:04 p.m. |
| August 15, 2025 | | Memphis Redbirds at Charlotte Knights | 7:04 p.m. |
| August 16, 2025 | | Memphis Redbirds at Charlotte Knights | 6:05 p.m. |
| August 17, 2025 | | Memphis Redbirds at Charlotte Knights | 5:05 p.m. |
| August 19, 2025 | | Charlotte Knights at Norfolk Tides | 6:35 p.m. |
| August 20, 2025 | | Charlotte Knights at Norfolk Tides | 6:35 p.m. |
| August 21, 2025 | | Charlotte Knights at Norfolk Tides | 12:05 p.m. |
| August 22, 2025 | | Charlotte Knights at Norfolk Tides | 6:35 p.m. |
| August 23, 2025 | | Charlotte Knights at Norfolk Tides | 6:35 p.m. |
| August 24, 2025 | | Charlotte Knights at Norfolk Tides | 1:05 p.m. |
| August 26, 2025 | | Charlotte Knights at Nashville Sounds | 7:35 p.m. |
| August 27, 2025 | | Charlotte Knights at Nashville Sounds | 7:35 p.m. |
| August 28, 2025 | | Charlotte Knights at Nashville Sounds | 7:35 p.m. |
| August 29, 2025 | | Charlotte Knights at Nashville Sounds | 7:35 p.m. |
| August 30, 2025 | | Charlotte Knights at Nashville Sounds | 7:35 p.m. |
| August 31, 2025 | | Charlotte Knights at Nashville Sounds | 7:05 p.m. |
| September 2, 2025 | | Jacksonville Jumbo Shrimp at Charlotte Knights | 6:35 p.m. |
| September 3, 2025 | | Jacksonville Jumbo Shrimp at Charlotte Knights | 6:35 p.m. |
| September 4, 2025 | | Jacksonville Jumbo Shrimp at Charlotte Knights | 7:04 p.m. |
| September 5, 2025 | | Jacksonville Jumbo Shrimp at Charlotte Knights | 7:04 p.m. |
| September 6, 2025 | | Jacksonville Jumbo Shrimp at Charlotte Knights | 5:35 p.m. |
| September 7, 2025 | | Jacksonville Jumbo Shrimp at Charlotte Knights | 1:05 p.m. |
| September 9, 2025 | | Charlotte Knights at Omaha Storm Chasers | 1:05 p.m. |
| September 10, 2025 | | Charlotte Knights at Omaha Storm Chasers | 7:35 p.m. |
| September 11, 2025 | | Charlotte Knights at Omaha Storm Chasers | 7:35 p.m. |
| September 12, 2025 | | Charlotte Knights at Omaha Storm Chasers | 7:35 p.m. |
| September 13, 2025 | | Charlotte Knights at Omaha Storm Chasers | 7:05 p.m. |
| September 14, 2025 | | Charlotte Knights at Omaha Storm Chasers | 3:05 p.m. |
| September 16, 2025 | | Durham Bulls at Charlotte Knights | 6:35 p.m. |
| September 17, 2025 | | Durham Bulls at Charlotte Knights | 6:35 p.m. |
| September 18, 2025 | | Durham Bulls at Charlotte Knights | 7:04 p.m. |
| September 19, 2025 | | Durham Bulls at Charlotte Knights | 7:04 p.m. |
| September 20, 2025 | | Durham Bulls at Charlotte Knights | 5:35 p.m. |
| September 21, 2025 | | Durham Bulls at Charlotte Knights | TBD |
Charlotte Knights Schedule
